DK1392256T3 - Forbedret transdermalt behandlingssystem til behandling af Parkinsons sygdom - Google Patents

Forbedret transdermalt behandlingssystem til behandling af Parkinsons sygdom

Info

Publication number: DK1392256T3
Authority: DK; Denmark
Prior art keywords: disease; parkinson; treatment system; treat parkinson; transdermal treatment
Prior art date: 2001-05-08

Application number

DK02735338.2T

Other languages

English (en)

Inventor

Dietrich Wilhelm Schacht

Hans-Michael Wolff

Walter Mueller

Thomas Lauterbach

Original Assignee

Ucb Pharma Gmbh

Lohmann Therapie Syst Lts

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-08

Filing date

2002-05-06

Publication date

2010-08-02

2002-05-06 Application filed by Ucb Pharma Gmbh, Lohmann Therapie Syst Lts filed Critical Ucb Pharma Gmbh

2010-08-02 Application granted granted Critical

2010-08-02 Publication of DK1392256T3 publication Critical patent/DK1392256T3/da

Links

208000018737 Parkinson disease Diseases 0.000 title abstract 2
239000004480 active ingredient Substances 0.000 abstract 1
230000000648 anti-parkinson Effects 0.000 abstract 1
239000000939 antiparkinson agent Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
239000000902 placebo Substances 0.000 abstract 1
229940068196 placebo Drugs 0.000 abstract 1
229920001296 polysiloxane Polymers 0.000 abstract 1
KFQYTPMOWPVWEJ-INIZCTEOSA-N rotigotine Chemical compound CCCN([C@@H]1CC2=CC=CC(O)=C2CC1)CCC1=CC=CS1 KFQYTPMOWPVWEJ-INIZCTEOSA-N 0.000 abstract 1
229960003179 rotigotine Drugs 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Dermatology (AREA)
Neurosurgery (AREA)
Psychology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)

DK02735338.2T 2001-05-08 2002-05-06 Forbedret transdermalt behandlingssystem til behandling af Parkinsons sygdom DK1392256T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01111110A EP1256340B1 (en)	2001-05-08	2001-05-08	Improved transdermal therapeutic system for the treatment of Parkinson's disease
PCT/EP2002/004975 WO2002089777A1 (en)	2001-05-08	2002-05-06	Improved transdermal therapeutic system for the treatment of parkinson's disese

Publications (1)

Publication Number	Publication Date
DK1392256T3 true DK1392256T3 (da)	2010-08-02

Family

ID=8177357

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK01111110T DK1256340T3 (da)	2001-05-08	2001-05-08	Forbedret transdermalt, terapeutisk system til behandlingen af Parkinsons sygdom
DK02735338.2T DK1392256T3 (da)	2001-05-08	2002-05-06	Forbedret transdermalt behandlingssystem til behandling af Parkinsons sygdom

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK01111110T DK1256340T3 (da)	2001-05-08	2001-05-08	Forbedret transdermalt, terapeutisk system til behandlingen af Parkinsons sygdom

Country Status (17)

Country	Link
EP (3)	EP1256340B1 (da)
JP (1)	JP2004528359A (da)
KR (1)	KR100968293B1 (da)
CN (1)	CN100457095C (da)
AT (2)	ATE246919T1 (da)
AU (1)	AU2002310805B8 (da)
CY (1)	CY1111880T1 (da)
DE (2)	DE60100595T2 (da)
DK (2)	DK1256340T3 (da)
ES (2)	ES2203563T3 (da)
HK (1)	HK1049448B (da)
HU (1)	HU229353B1 (da)
PT (2)	PT1256340E (da)
RU (1)	RU2273477C2 (da)
SI (1)	SI1256340T1 (da)
WO (1)	WO2002089777A1 (da)
ZA (1)	ZA200209980B (da)

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DE10041478A1 (de)	2000-08-24	2002-03-14	Sanol Arznei Schwarz Gmbh	Neue pharmazeutische Zusammensetzung
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US8246979B2 (en)	2002-07-30	2012-08-21	Ucb Pharma Gmbh	Transdermal delivery system for the administration of rotigotine
US8246980B2 (en)	2002-07-30	2012-08-21	Ucb Pharma Gmbh	Transdermal delivery system
DE10234673B4 (de)	2002-07-30	2007-08-16	Schwarz Pharma Ag	Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren
EP1386605A1 (en) *	2002-07-30	2004-02-04	Schwarz Pharma Ag	Improved transdermal delivery system for the administration of rotigotine
DE10261696A1 (de) *	2002-12-30	2004-07-15	Schwarz Pharma Ag	Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base
DE10334187A1 (de) *	2003-07-26	2005-03-03	Schwarz Pharma Ag	Substituierte 2-Aminotetraline zur Behandlung von Depressionen
DE10334188B4 (de)	2003-07-26	2007-07-05	Schwarz Pharma Ag	Verwendung von Rotigotin zur Behandlung von Depressionen
US8815215B2 (en) †	2003-08-15	2014-08-26	Colgate-Palmolive Company	Hydrophobic tooth whitening system and methods of use
DE10338174A1 (de) *	2003-08-20	2005-03-24	Lts Lohmann Therapie-Systeme Ag	Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit
DE10359528A1 (de)	2003-12-18	2005-07-28	Schwarz Pharma Ag	(S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum
DE10361258A1 (de) *	2003-12-24	2005-07-28	Schwarz Pharma Ag	Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson
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US8344165B2 (en)	2007-05-30	2013-01-01	Chemagis Ltd.	Crystalline rotigotine base and preparation process therefor
RS54235B1 (sr)	2007-11-28	2015-12-31	Ucb Pharma Gmbh	Polimorfni oblik rotigotina
DE102008060203A1 (de)	2008-12-07	2010-06-10	Dietrich Wilhelm Schacht	Wirkstoffstabilisierende flächenförmige Vorrichtung
EP2201941A1 (de) *	2008-12-29	2010-06-30	UCB Pharma GmbH	Pflaster-Herstellungstechnologie
EP2281559A1 (en)	2009-06-26	2011-02-09	UCB Pharma GmbH	Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis
DE102009052972A1 (de)	2009-11-12	2011-09-15	Lts Lohmann Therapie-Systeme Ag	Verfahren zur Verhinderung der Kristallisation von Arzneistoffen in einem Polymerfilm
HRP20181173T1 (hr)	2009-12-22	2018-09-21	Ucb Biopharma Sprl	Polivinilpirolidon za stabilizaciju čvrste disperzije nekristalnog oblika rotigotina
IN2012DN06562A (da)	2010-02-05	2015-10-23	Ucb Pharma Gmbh
AU2011268871C1 (en)	2010-06-25	2015-06-04	Ucb Pharma Gmbh	Processes for the resolution of nitrogen substituted (S) - 5 -alkoxy- 2 -aminotetralin derivatives
CN102475692A (zh) *	2010-11-29	2012-05-30	重庆医药工业研究院有限责任公司	一种防止雷沙吉兰挥发的透皮贴片
EP2559435A1 (en)	2011-08-19	2013-02-20	UCB Pharma GmbH	Rotigotine in the treatment of hemispatial neglect, stroke and deficits following stroke
CN102499906B (zh) *	2011-10-12	2013-04-17	长春健欣生物医药科技开发有限公司	一种罗替戈汀盐酸盐或自由碱成膜凝胶制剂及其制备方法
DE102012013421A1 (de)	2012-07-03	2014-01-09	Alfred E. Tiefenbacher (Gmbh & Co. Kg)	Transdermales therapeutisches System (TTS) mit Rotigotin
DE102012013439A1 (de)	2012-07-03	2014-01-23	Alfred E. Tiefenbacher (Gmbh & Co. Kg)	Transdermales therapeutisches System umfassend Rotigotin und Kristallisationsinhibitor
WO2013075822A1 (en)	2011-11-22	2013-05-30	Alfred E. Tiefenbacher (Gmbh & Co. Kg)	Transdermal therapeutic system (tts) with rotigotine
CA2878376C (en) *	2012-07-05	2018-08-07	Sk Chemicals Co., Ltd.	Transdermally absorbable preparation containing rotigotine
TW201431570A (zh)	2012-11-22	2014-08-16	Ucb Pharma Gmbh	用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片
WO2014198422A1 (de) *	2013-06-14	2014-12-18	Tesa Labtec Gmbh	Transdermales therapiesystem (tts) mit rotigotin
CA2916183C (en)	2013-07-03	2022-03-29	Lts Lohmann Therapie-Systeme Ag	Transdermal therapeutic system with electronic component
JP6895755B2 (ja)	2014-05-20	2021-06-30	エルテーエスローマンテラピー−ジステーメアーゲー	経皮送達システムにおける活性薬剤の放出を調節するための方法
EP4238580A3 (en)	2014-05-20	2023-10-25	LTS Lohmann Therapie-Systeme AG	Transdermal delivery system including an interface mediator
JP6573913B2 (ja) *	2014-05-20	2019-09-11	エルテーエスローマンテラピー−ジステーメアーゲー	ロチゴチンを含む経皮送達システム
PL3854388T3 (pl)	2020-01-24	2024-02-26	Luye Pharma Switzerland Ag	Transdermalny system terapeutyczny z substancją czynną rotygotyną i co najmniej jednym klejem silikonowym nieodpornym na działanie amin

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2001
- 2001-05-08 AT AT01111110T patent/ATE246919T1/de active
- 2001-05-08 DE DE60100595T patent/DE60100595T2/de not_active Expired - Lifetime
- 2001-05-08 SI SI200130030T patent/SI1256340T1/xx unknown
- 2001-05-08 PT PT01111110T patent/PT1256340E/pt unknown
- 2001-05-08 ES ES01111110T patent/ES2203563T3/es not_active Expired - Lifetime
- 2001-05-08 EP EP01111110A patent/EP1256340B1/en not_active Expired - Lifetime
- 2001-05-08 DK DK01111110T patent/DK1256340T3/da active
- 2001-05-08 EP EP03002051A patent/EP1325742A1/en not_active Withdrawn
2002
- 2002-05-06 ES ES02735338T patent/ES2344782T3/es not_active Expired - Lifetime
- 2002-05-06 WO PCT/EP2002/004975 patent/WO2002089777A1/en not_active Ceased
- 2002-05-06 DE DE60236078T patent/DE60236078D1/de not_active Expired - Lifetime
- 2002-05-06 DK DK02735338.2T patent/DK1392256T3/da active
- 2002-05-06 KR KR1020027018012A patent/KR100968293B1/ko not_active Expired - Lifetime
- 2002-05-06 JP JP2002586914A patent/JP2004528359A/ja not_active Withdrawn
- 2002-05-06 HU HU0302897A patent/HU229353B1/hu unknown
- 2002-05-06 EP EP02735338A patent/EP1392256B1/en not_active Expired - Lifetime
- 2002-05-06 RU RU2003128642/14A patent/RU2273477C2/ru active IP Right Revival
- 2002-05-06 AT AT02735338T patent/ATE464886T1/de active
- 2002-05-06 AU AU2002310805A patent/AU2002310805B8/en not_active Ceased
- 2002-05-06 CN CNB028015827A patent/CN100457095C/zh not_active Expired - Lifetime
- 2002-05-06 PT PT02735338T patent/PT1392256E/pt unknown
- 2002-12-10 ZA ZA200209980A patent/ZA200209980B/xx unknown
2003
- 2003-03-05 HK HK03101634.7A patent/HK1049448B/en unknown
2010
- 2010-07-06 CY CY20101100624T patent/CY1111880T1/el unknown

Also Published As

Publication number	Publication date
KR100968293B1 (ko)	2010-07-07
AU2002310805B8 (en)	2006-01-12
EP1256340A1 (en)	2002-11-13
DE60100595T2 (de)	2004-06-24
EP1392256B1 (en)	2010-04-21
WO2002089777A1 (en)	2002-11-14
HK1061194A1 (en)	2004-09-10
ES2344782T3 (es)	2010-09-07
ZA200209980B (en)	2003-02-24
HU229353B1 (en)	2013-11-28
DE60100595D1 (de)	2003-09-18
DE60236078D1 (de)	2010-06-02
JP2004528359A (ja)	2004-09-16
RU2273477C2 (ru)	2006-04-10
PT1392256E (pt)	2010-07-13
KR20030025941A (ko)	2003-03-29
ATE246919T1 (de)	2003-08-15
HUP0302897A3 (en)	2005-02-28
EP1392256A1 (en)	2004-03-03
CY1111880T1 (el)	2015-11-04
EP1256340B1 (en)	2003-08-13
RU2003128642A (ru)	2005-03-27
HK1049448B (en)	2003-12-12
AU2002310805B2 (en)	2005-09-08
EP1325742A1 (en)	2003-07-09
PT1256340E (pt)	2003-12-31
CN100457095C (zh)	2009-02-04
HK1049448A1 (en)	2003-05-16
ES2203563T3 (es)	2004-04-16
ATE464886T1 (de)	2010-05-15
HUP0302897A2 (hu)	2003-12-29
CN1462185A (zh)	2003-12-17
DK1256340T3 (da)	2003-12-01
SI1256340T1 (en)	2003-12-31

Publication	Publication Date	Title
DK1256340T3 (da)	2003-12-01	Forbedret transdermalt, terapeutisk system til behandlingen af Parkinsons sygdom
DK1256339T3 (da)	2004-02-09	Transdermalt terapeutisk system for opnåelse af høje plasmaniveauer af rotigotin i behandlingen af Parkinsons sygdom
HUP0102728A2 (hu)	2002-03-28	Módszerek és transzdermális készítmények fájdalom csillapítására
DE60121301D1 (de)	2006-08-17	Flibanserin zur Behandlung extrapyramidaler Bewegungsstörungen
DE60331236D1 (de)	2010-03-25	Orale zusammensetzungen zur behandlung von diabetes
DK1623703T3 (da)	2011-11-28	Hydrocodonformuleringer med kontrolleret frigivelse
BR0205722A (pt)	2005-04-05	Formulação de liberação prolongada e método para o tratamento de um paciente que sofre de dor
ATE387912T1 (de)	2008-03-15	Transepikutane darreichungsform zur behandlung des restless leg syndroms
DK0998287T3 (da)	2003-09-01	Anvendelse af levobupivacain
PT1383752E (pt)	2005-11-30	3-piperidinopropiofenonas deuteradas assim como farmacos contendo estes compostos
DE60126980D1 (de)	2007-04-12	Therapeutische agentien und methoden ihrer verwendung zur behandlung von amyloidogenen erkrankungen
DK1311249T3 (da)	2010-01-25	Sæt af transdermale terapeutiske systemer
ATE404192T1 (de)	2008-08-15	Verwendung von nefiracetam zur behandlung von postischemischer neurodegeneration
BR0104586A (pt)	2002-01-08	Método para tratamento de neurodegeneração
DK1492539T3 (da)	2006-10-30	Statin-terapi til forögelse af kognitiv funktion
DK1196176T3 (da)	2004-06-14	Anvendelse af beta-naphthoquinonderivater til fremstilling af lægemidler, der har en hæmmende virkning på hjernens afgivelse af glutamat
ECSP045056A (es)	2004-08-27	Composiciones de valdecoxib de disgregación intraoral preparadas mediante un procedimiento de desecación por pulverizacion
SE0102888D0 (sv)	2001-08-29	New formulation
TR200301916T4 (tr)	2004-01-21	Rotigotinin yüksek plazma seviyelerini kapsayan parkinson hastalığına yönelik transdermal terapötik sistem.