IT8423896A0 - Diacilderivati della glicerilfosforilcolina ad attivita' terapeutica, procedimento per laloro preparazione e relative composizioni farmaceutiche. - Google Patents

Diacilderivati della glicerilfosforilcolina ad attivita' terapeutica, procedimento per laloro preparazione e relative composizioni farmaceutiche.

Info

Publication number
IT8423896A0
IT8423896A0 IT8423896A IT2389684A IT8423896A0 IT 8423896 A0 IT8423896 A0 IT 8423896A0 IT 8423896 A IT8423896 A IT 8423896A IT 2389684 A IT2389684 A IT 2389684A IT 8423896 A0 IT8423896 A0 IT 8423896A0
Authority
IT
Italy
Prior art keywords
diacylderivatives
glycerylphosphorylcholine
procedure
preparation
pharmaceutical compositions
Prior art date
Application number
IT8423896A
Other languages
English (en)
Other versions
IT1178709B (it
IT8423896A1 (it
Inventor
Carlo Scolastico
Giovanni Tronconi
Original Assignee
Neopharmed Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neopharmed Spa filed Critical Neopharmed Spa
Publication of IT8423896A0 publication Critical patent/IT8423896A0/it
Priority to IT23896/84A priority Critical patent/IT1178709B/it
Priority to US06/803,474 priority patent/US4699901A/en
Priority to EP85115414A priority patent/EP0186803B1/en
Priority to CA000496835A priority patent/CA1300152C/en
Priority to DE8585115414T priority patent/DE3573121D1/de
Priority to AT85115414T priority patent/ATE46517T1/de
Priority to ES549645A priority patent/ES8606372A1/es
Priority to PT81621A priority patent/PT81621B/pt
Priority to JP60272642A priority patent/JPS61171490A/ja
Publication of IT8423896A1 publication Critical patent/IT8423896A1/it
Priority to US07/070,542 priority patent/US4824978A/en
Application granted granted Critical
Publication of IT1178709B publication Critical patent/IT1178709B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C07F9/106—Adducts, complexes, salts of phosphatides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT23896/84A 1984-12-05 1984-12-05 Diacilderivati della glicerilfosforilcolina ad attivita'terapeutica, procedimento per la loro preparazione e relative composizioni farmaceutiche IT1178709B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT23896/84A IT1178709B (it) 1984-12-05 1984-12-05 Diacilderivati della glicerilfosforilcolina ad attivita'terapeutica, procedimento per la loro preparazione e relative composizioni farmaceutiche
US06/803,474 US4699901A (en) 1984-12-05 1985-12-02 Diacyl derivatives of glycerylphosphorylcholine, their preparation, and antihyperlipidemic compositions
DE8585115414T DE3573121D1 (en) 1984-12-05 1985-12-04 Diacylderivatives of glycerylphosphorylcholine having therapeutical activity, a process for their preparation and related pharmaceutical compositions
CA000496835A CA1300152C (en) 1984-12-05 1985-12-04 Diacylderivatives of glycerylphosphorylcholine having therapeutical activity, a process for their preparation and related pharmaceutical compositions
EP85115414A EP0186803B1 (en) 1984-12-05 1985-12-04 Diacylderivatives of glycerylphosphorylcholine having therapeutical activity, a process for their preparation and related pharmaceutical compositions
AT85115414T ATE46517T1 (de) 1984-12-05 1985-12-04 Diacylderivate von glycerylphosphorylcholin mit therapeutischen eigenschaften, verfahren zu ihrer herstellung und entsprechende pharmazeutische zusammensetzungen.
ES549645A ES8606372A1 (es) 1984-12-05 1985-12-05 Procedimiento para preparar derivados diacilicos de glice- rilfosforilcolina opticamente activa o racemica
PT81621A PT81621B (pt) 1984-12-05 1985-12-05 Processo para a preparacao de derivados da glicerilfosforilcolina possuindo actividade terapeutica e de suas composicoes farmaceuticas
JP60272642A JPS61171490A (ja) 1984-12-05 1985-12-05 グリセリルホスホリルコリンのジアシル誘導体
US07/070,542 US4824978A (en) 1984-12-05 1987-07-07 Complexes of glycerylphosphorylcholine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23896/84A IT1178709B (it) 1984-12-05 1984-12-05 Diacilderivati della glicerilfosforilcolina ad attivita'terapeutica, procedimento per la loro preparazione e relative composizioni farmaceutiche

Publications (3)

Publication Number Publication Date
IT8423896A0 true IT8423896A0 (it) 1984-12-05
IT8423896A1 IT8423896A1 (it) 1986-06-05
IT1178709B IT1178709B (it) 1987-09-16

Family

ID=11210716

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23896/84A IT1178709B (it) 1984-12-05 1984-12-05 Diacilderivati della glicerilfosforilcolina ad attivita'terapeutica, procedimento per la loro preparazione e relative composizioni farmaceutiche

Country Status (9)

Country Link
US (2) US4699901A (it)
EP (1) EP0186803B1 (it)
JP (1) JPS61171490A (it)
AT (1) ATE46517T1 (it)
CA (1) CA1300152C (it)
DE (1) DE3573121D1 (it)
ES (1) ES8606372A1 (it)
IT (1) IT1178709B (it)
PT (1) PT81621B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1178709B (it) * 1984-12-05 1987-09-16 Neopharmed Spa Diacilderivati della glicerilfosforilcolina ad attivita'terapeutica, procedimento per la loro preparazione e relative composizioni farmaceutiche
IT1201477B (it) * 1985-10-04 1989-02-02 Istituto Chemioterapico Procedimento per la preparazione di l-alfa-glicerilfosforilcolina,l-alfa-glicerilfosforiletanolommina e l-alfa-glicerilfosforilinositolo da lecitine grezze e/o deoleate
EP0329053A1 (en) * 1988-02-15 1989-08-23 MAGIS FARMACEUTICI S.p.A. Choline esters of glycerophosphoric acids
IT1216535B (it) * 1988-03-28 1990-03-08 Magis Farmaceutici O_(1,2_di_0_acetilglicero_3_fosforil)etanolamina, procedimento per la sua preparazione e suo uso terapeutico.
JPH0745507B2 (ja) * 1988-06-02 1995-05-17 和光純薬工業株式会社 ホスファチジルコリン誘導体の製造方法
US4983592A (en) * 1988-12-19 1991-01-08 American Cyanamid Co. Bis-arylphosphate ester antagonists of platelet activating factor
US20110015154A1 (en) * 2009-07-20 2011-01-20 Kellermann Gottfried H Supporting acetylcholine function
US20110098265A1 (en) * 2009-10-28 2011-04-28 Neuroscience, Inc. Methods for reducing cravings and impulses associated with addictive and compulsive behaviors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2864848A (en) * 1954-07-19 1958-12-16 Ca Nat Research Council Method of producing l-alpha-glycerylphosphorylcholine
DK104583A (da) * 1982-03-22 1983-09-23 Fujisawa Pharmaceutical Co Fremgangsmaade til fremstilling af phospholipider
IT1178709B (it) * 1984-12-05 1987-09-16 Neopharmed Spa Diacilderivati della glicerilfosforilcolina ad attivita'terapeutica, procedimento per la loro preparazione e relative composizioni farmaceutiche

Also Published As

Publication number Publication date
DE3573121D1 (en) 1989-10-26
ES549645A0 (es) 1986-04-16
EP0186803B1 (en) 1989-09-20
US4824978A (en) 1989-04-25
US4699901A (en) 1987-10-13
EP0186803A2 (en) 1986-07-09
IT1178709B (it) 1987-09-16
ATE46517T1 (de) 1989-10-15
IT8423896A1 (it) 1986-06-05
PT81621B (pt) 1987-10-20
EP0186803A3 (en) 1987-06-16
ES8606372A1 (es) 1986-04-16
JPS61171490A (ja) 1986-08-02
PT81621A (en) 1986-01-02
CA1300152C (en) 1992-05-05

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