ATE468107T1 - Verfahren und zusammensetzung zur behandlung von trockenen augen - Google Patents

Verfahren und zusammensetzung zur behandlung von trockenen augen

Info

Publication number: ATE468107T1
Authority: AT; Austria
Prior art keywords: film; eye; composition; mixture; emulsion
Prior art date: 2001-11-01

Application number

AT01982692T

Other languages

English (en)

Inventor

Simon Benita

Gregory Lambert

Original Assignee

Yissum Res Dev Co

Novagali Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-01

Filing date

2001-11-01

Publication date

2010-06-15

2001-11-01 Application filed by Yissum Res Dev Co, Novagali Pharma Sa filed Critical Yissum Res Dev Co

2010-06-15 Application granted granted Critical

2010-06-15 Publication of ATE468107T1 publication Critical patent/ATE468107T1/de

Links

239000000203 mixture Substances 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 2
239000000839 emulsion Substances 0.000 abstract 2
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
229930105110 Cyclosporin A Natural products 0.000 abstract 1
108010036949 Cyclosporine Proteins 0.000 abstract 1
208000003556 Dry Eye Syndromes Diseases 0.000 abstract 1
206010013774 Dry eye Diseases 0.000 abstract 1
125000000129 anionic group Chemical group 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
229930182912 cyclosporin Natural products 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000003995 emulsifying agent Substances 0.000 abstract 1
230000008020 evaporation Effects 0.000 abstract 1
238000001704 evaporation Methods 0.000 abstract 1
208000030533 eye disease Diseases 0.000 abstract 1
150000002632 lipids Chemical class 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
150000003904 phospholipids Chemical class 0.000 abstract 1
229940124597 therapeutic agent Drugs 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Ophthalmology & Optometry (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)

AT01982692T 2001-11-01 2001-11-01 Verfahren und zusammensetzung zur behandlung von trockenen augen ATE468107T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/IL2001/001015 WO2003053405A1 (en)	2001-11-01	2001-11-01	Method and composition for dry eye treatment

Publications (1)

Publication Number	Publication Date
ATE468107T1 true ATE468107T1 (de)	2010-06-15

Family

ID=11043109

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01982692T ATE468107T1 (de)	2001-11-01	2001-11-01	Verfahren und zusammensetzung zur behandlung von trockenen augen

Country Status (10)

Country	Link
EP (1)	EP1441696B1 (de)
JP (1)	JP2005513097A (de)
CN (1)	CN100335036C (de)
AT (1)	ATE468107T1 (de)
AU (1)	AU2002214233A1 (de)
CA (1)	CA2464243C (de)
DE (1)	DE60142187D1 (de)
ES (1)	ES2343512T3 (de)
IL (1)	IL161588A0 (de)
WO (1)	WO2003053405A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20050059583A1 (en)	2003-09-15	2005-03-17	Allergan, Inc.	Methods of providing therapeutic effects using cyclosporin components
WO2006003519A2 (en) *	2004-07-02	2006-01-12	Novagali Pharma Sa	Use of emulsions for intra: and periocular injection
EP1611879B1 (de) *	2004-07-02	2009-08-12	Novagali Pharma SA	Verwendung von Emulsionen zur intra- und periocularen Injection
JP5272307B2 (ja) *	2004-07-16	2013-08-28	大正製薬株式会社	水性点眼剤
ES2314354T3 (es)	2004-11-09	2009-03-16	Novagali Pharma S.A.	Emulsion de tipo aceite en agua con baja concentracion de agente cationico y potencial zeta positivo.
AU2005304035B2 (en) *	2004-11-09	2010-07-22	Santen Sas	Ophthalmic oil-in-water type emulsion with stable positive zeta potential
BRPI0609227A2 (pt) *	2005-05-10	2010-03-09	Alcon Inc	composições de suspensão de nepafenac e outros fármacos oftálmicos, bem como uso das referidas composições no tratamento tópico de distúrbios oftálmicos
US7288520B2 (en) *	2005-07-13	2007-10-30	Allergan, Inc.	Cyclosporin compositions
US8288348B2 (en)	2005-07-13	2012-10-16	Allergan, Inc.	Cyclosporin compositions
PT1937212E (pt)	2005-10-10	2010-11-30	Novagali Pharma Sa	Emulsões oftálmicas contendo prostaglandinas
US11311477B2 (en)	2006-03-07	2022-04-26	Sgn Nanopharma Inc.	Ophthalmic preparations
US10137083B2 (en)	2006-03-07	2018-11-27	SGN Nanopharma Inc	Ophthalmic preparations
EP1834635B1 (de) *	2006-03-13	2011-07-06	Advanced in Vitro Cell Technologies, S.L.	Stabile Nanokapselsysteme für die Verabreichung von Wirkstoffen
US20070280902A1 (en)	2006-06-01	2007-12-06	Laura Rabinovich-Guilatt	Method for treating eye disease or conditions affecting the posterior segment of the eye
WO2008035246A2 (en)	2006-07-28	2008-03-27	Novagali Pharma Sa	Compositions containing quaternary ammonium compounds
CN101130058B (zh) *	2006-08-23	2011-10-05	华北制药集团新药研究开发有限责任公司	一种环孢菌素a眼用乳剂及其制备方法
WO2008120249A1 (en) *	2007-03-30	2008-10-09	Sifi S.P.A.	Pharmaceutical formulations based on apolar and polar lipids for ophthalmic use
EP2228058A1 (de)	2009-03-04	2010-09-15	Novagali Pharma S.A.	Anionische Öl-in-Wasser-Emulsion mit Prostaglandinen und Verwendungen dafür
EP2308468A1 (de) *	2009-10-08	2011-04-13	Novaliq GmbH	Neuartige pharmazeutische Zusammensetzung mit einem Makrolid-Immunosuppressivum
EP2389939A1 (de)	2010-05-28	2011-11-30	Novagali Pharma S.A.	Verwendung von Prostaglandinen F2alpha und Analoga zur Heilung von Horn- und Bindehautläsionen
AU2014209141B2 (en)	2013-01-24	2018-05-10	Palvella Therapeutics, Inc.	Compositions for transdermal delivery of mTOR inhibitors
EP3565520B1 (de)	2017-01-06	2026-02-25	Palvella Therapeutics, Inc.	Wasserfreie zusammensetzungen von mtor-hemmern und verfahren zur verwendung
US11000513B2 (en)	2018-07-02	2021-05-11	Palvella Therapeutics, Inc.	Anhydrous compositions of mTOR inhibitors and methods of use
CN109010270B (zh) *	2018-09-03	2021-07-30	辅必成（上海）医药科技有限公司	一种阳离子材料制备的眼用乳

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL101241A (en) *	1992-03-16	1997-11-20	Yissum Res Dev Co	Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier
ZA966579B (en) *	1995-08-04	1998-02-02	Wakamoto Pharma Co Ltd	O/W emulsion composition for eye drops.
DE10036871A1 (de) *	2000-07-28	2002-02-14	Pharmasol Gmbh	Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe

2001
- 2001-11-01 AT AT01982692T patent/ATE468107T1/de not_active IP Right Cessation
- 2001-11-01 WO PCT/IL2001/001015 patent/WO2003053405A1/en not_active Ceased
- 2001-11-01 AU AU2002214233A patent/AU2002214233A1/en not_active Abandoned
- 2001-11-01 EP EP01982692A patent/EP1441696B1/de not_active Expired - Lifetime
- 2001-11-01 IL IL16158801A patent/IL161588A0/xx active IP Right Grant
- 2001-11-01 ES ES01982692T patent/ES2343512T3/es not_active Expired - Lifetime
- 2001-11-01 JP JP2003554164A patent/JP2005513097A/ja active Pending
- 2001-11-01 CN CNB018237576A patent/CN100335036C/zh not_active Expired - Lifetime
- 2001-11-01 DE DE60142187T patent/DE60142187D1/de not_active Expired - Lifetime
- 2001-11-01 CA CA002464243A patent/CA2464243C/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JP2005513097A (ja)	2005-05-12
AU2002214233A1 (en)	2003-07-09
WO2003053405A1 (en)	2003-07-03
DE60142187D1 (de)	2010-07-01
HK1067316A1 (en)	2005-04-08
EP1441696B1 (de)	2010-05-19
IL161588A0 (en)	2004-09-27
CA2464243C (en)	2010-01-19
CA2464243A1 (en)	2003-07-03
CN100335036C (zh)	2007-09-05
CN1558751A (zh)	2004-12-29
ES2343512T3 (es)	2010-08-03
EP1441696A1 (de)	2004-08-04

Legal Events

Date	Code	Title	Description
2010-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE468107T1 (de)	2010-06-15	Verfahren und zusammensetzung zur behandlung von trockenen augen
ATE80290T1 (de)	1992-09-15	Loesung zur behandlung von ''dry-eye''erkrankungen.
JP2005513097A5 (de)	2005-12-22
BR0011883A (pt)	2002-03-05	Composição, produto para cabelos, produto para pele, e, processo de tratamento dos cabelos ou da pele
ES2159024T3 (es)	2001-09-16	Base que forma pelicula.
KR970704421A (ko)	1997-09-06	비누 조성물(Soap Composition)
BR9610849A (pt)	1999-07-13	Composição de limpeza pessoal e processo para a inibiçao da perda de umidade pela pele e proteção da pele
ES2161895T3 (es)	2001-12-16	Emulsiones especificas de la glandula lagrimal para aplicacion topica a tejidos oculares.
TR199800437T1 (xx)	1998-05-21	Mikro em�lsiyonlar.
NO20032664D0 (no)	2003-06-12	Vesikkeldannende hudolje inneholdende W/O-emulgeringsmidler med en hydrofil-lipofil balanse på 2-6, fremgangsmåte for fremstilling oganvendelse derav
ATE314451T1 (de)	2006-01-15	Zusammensetzung und verfahren zur textilpflege
BR9812071A (pt)	2000-09-26	Composição de limpeza de pele, proteção solar, processo para concomitantemente limpar a pele e depositar um agente de proteção solar sobre a mesma, e, produto
JPH05503527A (ja)	1993-06-10	人工涙液
US4814109A (en)	1989-03-21	Method of cleaning contact lenses
US5866145A (en)	1999-02-02	Body polisher
MX2022014226A (es)	2023-04-14	Composiciones para la administracion de agentes bioactivos en foliculos pilosos.
ATE326207T1 (de)	2006-06-15	Kosmetische zusammensetzung zur schminkproduktenentfernung und/oder zur hautreinigung in der form einer wasser-in-öl emulsion
ATE160936T1 (de)	1997-12-15	Wasser-in-öl emulsionen, die ein wasserlösliches alkylglycosid enthalten
US20040016410A1 (en)	2004-01-29	Method for neutralizing offensive chemical odors
YU2792A (sh)	1995-01-31	Disperzije finih čestica, antihelmintno efikasnih derivata, benzimidazola ili benztiazola ili pro-benzimidazola u vodi
FI4294360T3 (fi)	2025-07-11	Epidermaalisille lipideille ja fosfatidyyliglyserolille optimoituja ulkoisesti käytettäviä koostumuksia
US20090011050A1 (en)	2009-01-08	Skin Treatment Composition And Method
DE59901941D1 (de)	2002-08-08	Haarverformungsmittel
FR2799968B1 (fr)	2002-07-12	Emulsion eau-dans-huile et ses utilisations notamment dans le domaine cosmetique
ATE329570T1 (de)	2006-07-15	Emulsion enthaltend siliconöl- und co- lösungsmittelsystem enhaltend fettlösliche kosmetische wirkstoffe und daraus hergestelleten kosmetischen zubereitungen