ATE80290T1 - Loesung zur behandlung von ''dry-eye''erkrankungen. - Google Patents

Loesung zur behandlung von ''dry-eye''erkrankungen.

Info

Publication number
ATE80290T1
ATE80290T1 AT88115984T AT88115984T ATE80290T1 AT E80290 T1 ATE80290 T1 AT E80290T1 AT 88115984 T AT88115984 T AT 88115984T AT 88115984 T AT88115984 T AT 88115984T AT E80290 T1 ATE80290 T1 AT E80290T1
Authority
AT
Austria
Prior art keywords
dry eye
diseases
treat
solution
phospholipid
Prior art date
Application number
AT88115984T
Other languages
English (en)
Inventor
Thomas Glonek
Jack V Greiner
Donald R Korb
Original Assignee
Boston Ocular Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Ocular Res filed Critical Boston Ocular Res
Application granted granted Critical
Publication of ATE80290T1 publication Critical patent/ATE80290T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
AT88115984T 1987-10-23 1988-09-28 Loesung zur behandlung von ''dry-eye''erkrankungen. ATE80290T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/111,874 US4914088A (en) 1987-04-02 1987-10-23 Dry eye treatment solution and method
EP88115984A EP0312814B1 (de) 1987-10-23 1988-09-28 Lösung zur Behandlung von "Dry-Eye"-Erkrankungen

Publications (1)

Publication Number Publication Date
ATE80290T1 true ATE80290T1 (de) 1992-09-15

Family

ID=22340899

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88115984T ATE80290T1 (de) 1987-10-23 1988-09-28 Loesung zur behandlung von ''dry-eye''erkrankungen.

Country Status (6)

Country Link
US (1) US4914088A (de)
EP (1) EP0312814B1 (de)
JP (1) JP3036749B2 (de)
AT (1) ATE80290T1 (de)
DE (1) DE3874479T2 (de)
ES (1) ES2052664T3 (de)

Families Citing this family (142)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5278151A (en) * 1987-04-02 1994-01-11 Ocular Research Of Boston, Inc. Dry eye treatment solution
US5364632A (en) * 1989-04-05 1994-11-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions
AU655919B2 (en) * 1990-02-22 1995-01-19 Macnaught Pty Limited Artificial tears
ZA912797B (en) * 1990-05-29 1992-12-30 Boston Ocular Res Dry eye treatment process and solution
ATE132366T1 (de) * 1990-05-29 1996-01-15 Boston Ocular Res Zusammensetzung zur behandlung von dry eye erkrankungen
FR2673513B1 (fr) * 1991-03-05 1993-10-29 Institut Recherche Biologique Sa Nouvelles compositions dietetiques a base de lipides phosphoryles et leur utilisation dans l'amelioration des troubles de la vision.
ZA927277B (en) * 1991-10-02 1993-05-19 Boston Ocular Res Dry eye treatment process and solution.
US5290572A (en) * 1992-08-06 1994-03-01 Deo Corporation Opthalmic composition for treating dry eye
US5830508A (en) * 1992-08-06 1998-11-03 Deo Corporation Composition for treating dry eye
US5496811A (en) * 1992-08-28 1996-03-05 Pharmos Corp. Submicron emulsions as ocular drug delivery vehicles
TW274516B (de) * 1993-11-12 1996-04-21 Ciba Geigy Ag
DE69629230D1 (de) * 1995-03-24 2003-09-04 Ocular Res Of Bonton Inc Hydrogellinse mit Lipid-Vorbeschichtigung
DE19511322C2 (de) 1995-03-28 1999-09-02 Mann Gerhard Chem Pharm Fab Sterile Augengele mit einem Gehalt an mittelkettigen Triglyceriden und Verfahren zu deren Herstellung
US5616342A (en) * 1995-04-11 1997-04-01 Pdt, Inc. Emulsioin suitable for administering a poorly water-soluble photosensitizing compound and use thereof
US5696166A (en) * 1995-10-31 1997-12-09 Yanni; John M. Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders
US5738856A (en) * 1995-11-03 1998-04-14 Ocular Research Of Boston, Inc. Skin care preparation and method
IL120005A (en) 1997-01-14 2000-08-31 Ramot University Authority Of Pharmaceutical compositions for the treatment of the eye
ZA989513B (en) 1997-10-21 1999-04-21 Alcon Lab Inc Compositions containing histamine H2 agonists and methods of use in treating dry eye
EP0982025A1 (de) * 1998-08-28 2000-03-01 Wilhelm Prof. Dr. Stoffel Künstliche Tränen
WO2000038690A2 (en) 1998-12-24 2000-07-06 Alcon Laboratories, Inc. Prostaglandin e agonists for treatment of dry eye
AU2183900A (en) 1998-12-24 2000-07-31 Alcon Laboratories, Inc. Ep4 receptor agonists for treatment of dry eye
US6429194B1 (en) * 1999-03-01 2002-08-06 Vista Scientific Llc Mucin containing ophthalmic preparation
JP2002538124A (ja) 1999-03-01 2002-11-12 ヴィスタ サイエンティフィック エルエルシー ムチンを含む眼科用調合物
BR0015436A (pt) 1999-11-09 2002-07-16 Alcon Inc Sais de hidroxieicosatetraenoato, composições e métodos de uso no tratamento de distúrbios dos olhos secos
WO2001034553A2 (en) 1999-11-09 2001-05-17 Alcon Universal Ltd. 2,2-difluoro 15-hydroxyeicosatetraenoic acid analogs and methods of use
ES2220561T3 (es) 1999-11-09 2004-12-16 Alcon Inc. Composiciones que contienen derivados de acido hidroxieicosa tetraenoico y metodo de uso para tratar trastornos de la xeroftalmia.
US6458854B2 (en) 1999-11-09 2002-10-01 Alcon Universal Ltd. Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
US6552084B2 (en) 1999-11-09 2003-04-22 Alcon Universal Ltd. Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
EP1227809B1 (de) 1999-11-09 2005-04-06 Alcon Inc. Heteroatomunterbrochene analoge von15-hydroxyeicosatetraensäure und verfahren zu deren verwendung
ES2208440T3 (es) 1999-11-09 2004-06-16 Alcon Inc. Derivados del acido 15-hidroxieicosatetraenoico con cadena omega modificada utiles para el tratamiento del ojo seco.
PT1228030E (pt) 1999-11-09 2005-08-31 Alcon Inc Derivados benzenoidicos do acido 15-hidroxieicosatetraenoico e metodos para a sua utilizacao no tratamento das perturbacoes do olho seco
ATE258791T1 (de) 1999-11-09 2004-02-15 Alcon Inc Lipoxin-a4 und deren analoge zur behandlung von trockenen augen
DK1228027T3 (da) 1999-11-09 2004-07-19 Alcon Inc 3-heteroatomsubstituerede og to carbonhomologe af 15-HETE og fremgangsmåder til anvendelse
US6353032B1 (en) 1999-11-09 2002-03-05 Alcon Universal Ltd. Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
US6803385B2 (en) 1999-11-09 2004-10-12 Alcon, Inc. Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
MXPA02004700A (es) 1999-11-09 2004-09-10 Alcon Inc Compuestos relacionados con acido 15-hidroxieicosatetraenoico y metodos de uso.
WO2001034550A2 (en) 1999-11-09 2001-05-17 Alcon Universal Ltd. 15-hydroxyeicosatetraenoic acid analogs with enhanced metabolic stability and methods of their use in treating dry eye disorders
WO2001046134A1 (en) 1999-12-22 2001-06-28 Alcon Universal Ltd. 6-KETO PROSTAGLANDIN F1α AND ANALOGS FOR TREATING DRY EYE
DK1393277T3 (da) 2001-05-21 2006-10-30 Alcon Inc Anvendelse af NF-Kappa-B inhibitorer til behandling af öjentörhedslidelser
BR0209882A (pt) * 2001-05-21 2004-06-08 Alcon Inc Método para o tratamento de distúrbios de olho seco
US7112588B2 (en) * 2001-05-21 2006-09-26 Alcon, Inc. Use of proteasome inhibitors to treat dry eye disorders
ES2278049T3 (es) 2001-05-21 2007-08-01 Alcon, Inc. Uso de inhibidores de proteasoma para tratar trastornos de ojo seco.
US6872382B1 (en) 2001-05-21 2005-03-29 Alcon, Inc. Use of selective PDE IV inhibitors to treat dry eye disorders
US6645994B1 (en) 2001-06-01 2003-11-11 Alcon, Inc. Method of treating dry eye disorders
US6750250B1 (en) * 2001-07-12 2004-06-15 Alcon, Inc. 11,12-oxidoarachidonic acid derivatives and methods of their use in treating dry eye disorders
DE10141018A1 (de) * 2001-08-22 2003-03-13 Eth Zuerich Eidgenoessische Te Verwendung von negativ geladenen Phospholipiden, sowie Zusammensetzungen umfassend Phospholipide zur Behandlung des Auges
US20040214754A1 (en) * 2001-10-03 2004-10-28 Ellis Edward J. Ophthalmic preparation containing glycomacropeptide
US20040220089A1 (en) * 2001-10-03 2004-11-04 Ellis Edward J. Ophthalmic preparation containing glycoprotein
WO2003030894A1 (en) * 2001-10-11 2003-04-17 Alcon, Inc. Methods for treating dry eye
WO2003030892A1 (en) * 2001-10-11 2003-04-17 Alcon, Inc. Methods for treating dry eye
CA2462272A1 (en) * 2001-10-11 2003-04-17 Alcon, Inc. Methods for treating dry eye by a combination of an antiinflammatory steroid and a muc-1 secretagogue
US6656460B2 (en) 2001-11-01 2003-12-02 Yissum Research Development Method and composition for dry eye treatment
AU2003243282B2 (en) * 2002-05-17 2008-05-01 Othera Holding, Inc. Amelioration of the development of cataracts and other opthalmic diseases
US7897642B1 (en) * 2002-06-19 2011-03-01 Dr. Irvine Dubow Compositions and methods for dry eye syndrome
US8420699B1 (en) 2002-06-19 2013-04-16 Irvine L. Dubow Composition and methods of treatment using deionized and ozonated solution
JP2006502183A (ja) * 2002-09-20 2006-01-19 アルコン，インコーポレイテッド ドライアイ障害の処置のためのサイトカイン合成インヒビターの使用
PT1551417E (pt) * 2002-10-18 2008-10-31 Aqueous Pharma Ltd Formulação de lágrimas com três camadas
US7051156B2 (en) 2002-11-06 2006-05-23 Synology Inc. Raid-5 disk having cache memory
WO2004060274A2 (en) * 2002-12-20 2004-07-22 Alcon, Inc. Treatment of dry eye by restoring 15-lipoxygenase activity to ocular surface cells
US7235556B2 (en) * 2003-04-16 2007-06-26 Alcon, Inc. Methods of treating dry eye disorders
US7825134B2 (en) * 2003-05-19 2010-11-02 Othera Holding, Inc. Amelioration of cataracts, macular degeneration and other ophthalmic diseases
US20050182039A1 (en) * 2004-02-13 2005-08-18 Bausch & Lomb Incorporated Use of Loteprednol etabonate for the treatment of dry eye
US8455016B2 (en) 2004-03-12 2013-06-04 Melbj Holdings, Llc Treatment for meibomian gland dysfunction or obstruction
US20050202097A1 (en) * 2004-03-12 2005-09-15 Melbj Holdings, Llc, Florida Lubricant for the ocular surface
AU2005229006B9 (en) 2004-03-25 2011-05-19 Bausch & Lomb Incorporated Use of loteprednol etabonate for the treatment of dry eye
US7923471B2 (en) * 2004-05-14 2011-04-12 Alcon, Inc. Method of treating dry eye disorders and uveitis
PL1744736T3 (pl) * 2004-05-14 2010-03-31 Alcon Inc Sposób leczenia zespołu suchego oka i zapalenia błony naczyniowej oka
US20070265341A1 (en) * 2004-07-01 2007-11-15 The Schepens Eye Research Institute Inc. Compositions and methods for treating eye disorders and conditions
AU2005262392A1 (en) * 2004-07-01 2006-01-19 Johnson & Johnson Vision Care, Inc. Compositions and methods for treating eye disorders and conditions
US7223737B1 (en) 2004-08-13 2007-05-29 Alcon, Inc. Method of treating dry eye disorders using glycosides
WO2006065916A1 (en) * 2004-12-14 2006-06-22 Alcon, Inc. Method of treating dry eye disorders using 13(s)-hode and its analogs
US9161905B2 (en) 2005-01-12 2015-10-20 Ocular Research Of Boston, Inc. Dry eye treatment
EA035619B1 (ru) 2005-06-01 2020-07-16 ПиТиСи ТЕРАПЬЮТИКС, ИНК. Композиции для использования в способе лечения митохондриальных нарушений
US7981145B2 (en) 2005-07-18 2011-07-19 Tearscience Inc. Treatment of meibomian glands
WO2013003594A2 (en) 2011-06-28 2013-01-03 Tearscience, Inc. Methods and systems for treating meibomian gland dysfunction using radio-frequency energy
US8083787B2 (en) * 2005-07-18 2011-12-27 Tearscience, Inc. Method and apparatus for treating meibomian gland dysfunction
US7981146B2 (en) * 2006-05-15 2011-07-19 Tearscience Inc. Inner eyelid treatment for treating meibomian gland dysfunction
US20090043365A1 (en) * 2005-07-18 2009-02-12 Kolis Scientific, Inc. Methods, apparatuses, and systems for reducing intraocular pressure as a means of preventing or treating open-angle glaucoma
US8950405B2 (en) * 2006-05-15 2015-02-10 Tearscience, Inc. Treatment of obstructive disorders of the eye or eyelid
US7981095B2 (en) * 2005-07-18 2011-07-19 Tearscience, Inc. Methods for treating meibomian gland dysfunction employing fluid jet
US20070060988A1 (en) 2005-07-18 2007-03-15 Grenon Stephen M Melting meibomian gland obstructions
US20080114423A1 (en) 2006-05-15 2008-05-15 Grenon Stephen M Apparatus for inner eyelid treatment of meibomian gland dysfunction
WO2007058935A2 (en) * 2005-11-14 2007-05-24 Bausch & Lomb Incorporated Ophthalmic composition for dry eye therapy
RU2302231C1 (ru) * 2006-02-08 2007-07-10 Александр Егорович Петренко Глазные капли для лечения синдрома сухого глаза
EP1986636B1 (de) 2006-02-22 2013-04-24 Edison Pharmaceuticals, Inc. Phenol- und 1,4-benzochinon-derivate zur verwendung in der behandlung von erkrankungen der mitochondrien
US7745461B1 (en) 2006-02-27 2010-06-29 Alcon Research, Ltd. Method of treating dry eye disorders
ES2284398B2 (es) 2006-04-27 2008-12-16 Universidad Complutense De Madrid Formulacion de vesiculas liposomales en soluciones acuosas con caracteristicas de pelicula lagrimal.
US8007524B2 (en) * 2006-05-15 2011-08-30 Tearscience, Inc. Heat treatment and heat loss reduction for treating meibomian gland dysfunction
US8137390B2 (en) 2006-05-15 2012-03-20 Tearscience, Inc. System for providing heat treatment and heat loss reduction for treating meibomian gland dysfunction
US7981147B2 (en) * 2006-05-15 2011-07-19 Tearscience, Inc. Outer eyelid heat and pressure treatment for treating meibomian gland dysfunction
US9314369B2 (en) * 2006-05-15 2016-04-19 Tearscience, Inc. System for inner eyelid treatment of meibomian gland dysfunction
US7976573B2 (en) * 2006-05-15 2011-07-12 Tearscience, Inc. Inner eyelid heat and pressure treatment for treating meibomian gland dysfunction
US8128673B2 (en) 2006-05-15 2012-03-06 Tearscience, Inc. System for inner eyelid heat and pressure treatment for treating meibomian gland dysfunction
US8128674B2 (en) 2006-05-15 2012-03-06 Tearscience, Inc. System for outer eyelid heat and pressure treatment for treating meibomian gland dysfunction
CA2650478C (en) * 2006-07-07 2013-08-13 Bausch & Lomb Incorporated Compositions comprising a dissociated glucocorticoid receptor agonist and an immunosuppressive agent for treating dry eye
WO2008027069A1 (en) * 2006-08-21 2008-03-06 Tearscience, Inc. Method and apparatus for treating meibomian gland dysfunction employing fluid
US20080057022A1 (en) * 2006-08-30 2008-03-06 Erning Xia Ophthalmic Pharmaceutical Compositions and Uses Thereof
WO2008052037A2 (en) * 2006-10-24 2008-05-02 Alcon Research, Ltd. Packaging materials for formulations containing 2-pyrrolidone derivatives
US20080095863A1 (en) * 2006-10-24 2008-04-24 Alcon Manufacturing Ltd. 2-pyrrolidone derivatives for preservation of ophthalmic, otic and nasal compositions
US20080132475A1 (en) * 2006-12-05 2008-06-05 Charles Gerald Connor Treatment for dry eye
US20080188573A1 (en) * 2007-02-02 2008-08-07 Alcon Research, Ltd. Use of thy1-fp transgenic mouse for the identification of ophthalmic agents
WO2008154129A1 (en) * 2007-06-08 2008-12-18 Bausch & Lomb Incorporated Pharmaceutical compositions and method for treating, reducing, ameliorating, alleviating, or preventing dry eye
USD614303S1 (en) 2008-02-06 2010-04-20 Tearscience, Inc. Eye treatment apparatus
USD613408S1 (en) 2008-02-06 2010-04-06 Tearscience, Inc. Eye treatment head gear
USD617443S1 (en) 2008-02-06 2010-06-08 Tearscience, Inc. Eye treatment goggles
EP2344142B1 (de) 2008-09-10 2024-06-26 PTC Therapeutics, Inc. Behandlung von pervasiven entwicklungsstörungen mit redox-aktiven therapeutika
US8539938B2 (en) * 2009-03-12 2013-09-24 Ford Global Technologies, Llc Fuel systems and methods for controlling fuel systems in a vehicle with multiple fuel tanks
CA2777479C (en) 2009-04-28 2017-10-17 Ptc Therapeutics, Inc. Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones
USD638128S1 (en) 2009-10-06 2011-05-17 Tearscience, Inc. Ocular device design
TWI478730B (zh) * 2009-12-03 2015-04-01 Alcon Res Ltd 眼科乳劑
US8658614B2 (en) 2010-08-13 2014-02-25 The University of Texas Health Science Center Aptamer-containing compositions and methods for targeting E-selectin
US9161531B2 (en) 2011-02-23 2015-10-20 Donald R. Korb High alcohol content sanitizer
RU2460517C1 (ru) * 2011-07-14 2012-09-10 Федеральное государственное учреждение "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по высокотехнологичной медицинской помощи" Фармацевтическая композиция для комплексного лечения заболеваний глазной поверхности у больных с первичной открытоугольной глаукомой
US8859525B2 (en) 2011-07-19 2014-10-14 Bausch & Lomb Incorporated Pharmaceutical compositions comprising mushroom-based polysaccharides and uses thereof
RU2470630C1 (ru) * 2011-07-28 2012-12-27 Общество с ограниченной ответственностью "Научно-производственная компания "ФАРМАСОФТ" (ООО "НПК "ФАРМАСОФТ") Средство для лечения воспалительных заболеваний глаз человека и животных, для стимуляции репаративных процессов и эпителизации
CA2851492A1 (en) 2011-09-22 2013-03-28 Bausch & Lomb Incorporated Ophthalmic gel compositions
US10842670B2 (en) 2012-08-22 2020-11-24 Johnson & Johnson Vision Care, Inc. Apparatuses and methods for diagnosing and/or treating lipid transport deficiency in ocular tear films, and related components and devices
US9763827B2 (en) 2013-04-30 2017-09-19 Tear Film Innovations, Inc. Systems and methods for the treatment of eye conditions
WO2014179356A1 (en) 2013-04-30 2014-11-06 Tear Film Innovations Llc Systems and methods for the treatment of eye conditions
WO2015138604A1 (en) 2014-03-12 2015-09-17 University Of Virginia Patent Foundation Compositions and methods for treating eye infections and disease
WO2015171516A1 (en) 2014-05-05 2015-11-12 Thetis Pharmaceuticals Llc Compositions and methods relating to ionic salts of peptides
CN107074884A (zh) 2014-06-18 2017-08-18 西蒂斯制药有限责任公司 活性剂的矿物质氨基酸复合物
US12414937B2 (en) 2015-11-05 2025-09-16 University Of Louisville Research Foundation, Inc. Local and regional anesthesia and analgesia
EP3389646A1 (de) 2015-12-17 2018-10-24 BioElectron Technology Corporation Flouralkyl, flouralkoxy, phenoxy, heteroaryloxy, alkoxy und amin-1,4-benzochinon-derivate zur behandlung von oxidativen stresserkrankungen
KR102437682B1 (ko) 2016-06-03 2022-08-29 테티스 파마수티컬스 엘엘씨 특화된 사전 해소 매개체의 염에 관한 조성물 및 방법
US10974063B2 (en) 2016-06-30 2021-04-13 Alcon Inc. Light therapy for eyelash growth
US12233017B2 (en) 2016-10-14 2025-02-25 Olympic Ophthalmics, Inc. Quiet handheld devices and methods for treatment of disorders
TWI913170B (zh) 2018-02-21 2026-01-21 瑞士商愛爾康公司 基於脂質的眼用乳劑
US11147735B2 (en) 2018-02-26 2021-10-19 Olympic Ophthalmics, Inc. Therapeutic handheld devices for disorders
US11253395B2 (en) 2018-06-01 2022-02-22 Aurora Tears Technology, Inc. Systems and methods for generating and applying biomimicry tear films
US12558258B2 (en) 2018-06-01 2026-02-24 Aurora Tears Technology, Inc. Systems and methods for administering fluid compositions
US11464672B2 (en) 2018-06-01 2022-10-11 Aurora Tears Technology, Inc. Systems and methods for generating and applying biomimicry tear films
CN113056353B (zh) * 2018-09-25 2022-11-01 奥尔德拉医疗公司 用于治疗干眼病的调配物
WO2020123362A1 (en) 2018-12-10 2020-06-18 EternaTear, Inc. Ophthalmic formulations providing durable ocular lubrication
EP4104818A1 (de) 2021-06-17 2022-12-21 Skeye Pharma GbR Ophthalmische zusammensetzung mit xanthohumol
EP4104817A1 (de) 2021-06-17 2022-12-21 Skeye Pharma GbR Ophthalmische zusammensetzung mit astragalosid iv
US11679078B1 (en) 2022-03-08 2023-06-20 EternaTear, Inc. Ophthalmic formulations and related methods
US11471475B1 (en) 2022-03-08 2022-10-18 Ralph P. Stone Ophthalmic suspension vehicles and related methods for pharmaceutical ingredient delivery
WO2023187672A1 (en) 2022-03-31 2023-10-05 Alcon Inc. Ophthalmic compositions
EP4302767B1 (de) 2022-07-04 2024-10-02 Skeye Pharma GmbH Eriocitrin enthaltende ophthalmische zusammensetzung zur behandlung von trockenem-augen-syndrom
US20260144812A1 (en) 2024-11-27 2026-05-28 Alcon Inc. Antioxidant ophthalmic emulsion
WO2026115440A1 (en) 2024-11-27 2026-06-04 Alcon Inc. Stable ophthalmic emulsion

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3869482A (en) * 1972-07-31 1975-03-04 Etapharm Chem Pharm Lab G M B Method of producing highly purified phosphatides
US4677099A (en) * 1981-09-04 1987-06-30 Yeda Research And Development Co., Ltd. Medical processes employing a novel lipid fraction
JPS59500952A (ja) * 1982-03-29 1984-05-31 ザ　リポソ−ム　カンパニ−、インコ−ポレ−テッド 安定なプルリラメラベシクル類
WO1983003383A1 (en) * 1982-03-29 1983-10-13 Liposome Co Inc Stable plurilamellar vesicles
US4421748A (en) * 1982-07-13 1983-12-20 Trager Seymour F Artificial tear aid
FR2596651B1 (fr) * 1986-04-08 1989-11-10 Centre Nat Rech Scient Nouveaux liposomes a base de phosphatidylinositolmannosides, et compositions pharmaceutiques les contenant
EP0316345A1 (de) * 1986-07-28 1989-05-24 Liposome Technology, Inc. Liposome mit verbesserter bindung an schleimgewebe

Also Published As

Publication number Publication date
EP0312814A1 (de) 1989-04-26
US4914088A (en) 1990-04-03
JPH01146824A (ja) 1989-06-08
JP3036749B2 (ja) 2000-04-24
DE3874479D1 (de) 1992-10-15
ES2052664T3 (es) 1994-07-16
DE3874479T2 (de) 1993-02-18
EP0312814B1 (de) 1992-09-09

Similar Documents

Publication Publication Date Title
DE3874479D1 (de) Loesung zur behandlung von "dry-eye"-erkrankungen.
DE69115990D1 (de) Zusammensetzung zur Behandlung von Dry Eye Erkrankungen
DE69739792D1 (de) Verfahren zur Behandlung von Augenerkrankungen
DE69535758D1 (de) Lipid-analoge zur behandlung von viralen infektionen
ATE175348T1 (de) L - deprenyl zur behandlung von makulärer degeneration
ATE258796T1 (de) Verwendung von vitamin d4-derivaten zur behandlung von hauterkrankungen
DE69121561D1 (de) Verwendung von 3-guanidinopropionsäure zur herstellung eines medikaments zur behandlung und prävention von fettsucht
ATE179888T1 (de) Ophthalmische zubereitung zur behandlung oder prävention von trockenem auge und krankheiten, die dadurch verursacht werden, enthaltend 12- sulfodehydroabietsäure
DE3865368D1 (de) Thiophensulfonamide zur behandlung von glaukom.
DE69202019D1 (de) Verwendung von essentiellen Fettsäuren zur Herstellung eines Arzneimittels zur Behandlung von AIDS.
DE68904462D1 (de) 4-chinolincarbonsaeure-derivate, brauchbar zur behandlung von haut- und muco-epithelial-gewebekrankheiten.
DE3872701D1 (de) Prostaglandin-derivate zur behandlung von glaucoma oder augenueberdruck.
ATE148628T1 (de) 5-methylisoxazol-4-carbonsäure-anilide und 2- hydroxyethyliden-cyanoessigsäure-anilide zur behandlung von augenkrankheiten
ES2032529T3 (es) Una emulsion de agua y aceite termo-esterilizable.
ATE106736T1 (de) Verwendung von dimethylpolysiloxan zur behandlung von erkrankungen des gastrointestinaltraktes.
SE8801710L (sv) New ophtalmological composition of matter
ATE143804T1 (de) Zusammensetzung zur behandlung von mastitis und metritis
ATE112960T1 (de) Anthocyanidine zur behandlung von augenkrankheiten.
DE58902451D1 (de) (s)-emopamil zur anwendung bei der behandlung von migraene.
ATE58456T1 (de) Zusammensetzung zur behandlung von laeuseplagen.
EP0329948A3 (de) Verwendung von Betablockern zur Behandlung der Progression der kindlichen Achsenmyopie
ATE33555T1 (de) Therapeutische zusammensetzung fuer die behandlung von schwierigkeiten des anpassungsvermoegens des auges.
DE69525631D1 (de) Verwendung von prostaglandinen zur herstellung eines arzneimittels zur prävention und behandlung des sekundären katarakts
KR930702015A (ko) 각막 장해 치료제
DE69307702D1 (de) Verwendung von (e) - 2 - (p -fluorophenethyl)- 3 - fluoroallylamine zur behandlung der alzheimerschen krankheit

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee