ATE468863T1 - Gentherapie für zerebrale gefässerkrankungen - Google Patents
Gentherapie für zerebrale gefässerkrankungenInfo
- Publication number
- ATE468863T1 ATE468863T1 AT00961050T AT00961050T ATE468863T1 AT E468863 T1 ATE468863 T1 AT E468863T1 AT 00961050 T AT00961050 T AT 00961050T AT 00961050 T AT00961050 T AT 00961050T AT E468863 T1 ATE468863 T1 AT E468863T1
- Authority
- AT
- Austria
- Prior art keywords
- cerebral
- gene therapy
- vascular diseases
- cerebrovascular
- cerebral vascular
- Prior art date
Links
- 230000002490 cerebral effect Effects 0.000 title 1
- 238000001415 gene therapy Methods 0.000 title 1
- 208000019553 vascular disease Diseases 0.000 title 1
- 102000003745 Hepatocyte Growth Factor Human genes 0.000 abstract 2
- 108090000100 Hepatocyte Growth Factor Proteins 0.000 abstract 2
- 108010073929 Vascular Endothelial Growth Factor A Proteins 0.000 abstract 2
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 abstract 2
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 abstract 2
- 208000026106 cerebrovascular disease Diseases 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 206010008088 Cerebral artery embolism Diseases 0.000 abstract 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 abstract 1
- 206010008132 Cerebral thrombosis Diseases 0.000 abstract 1
- 201000001429 Intracranial Thrombosis Diseases 0.000 abstract 1
- 208000009433 Moyamoya Disease Diseases 0.000 abstract 1
- 206010061876 Obstruction Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 206010008118 cerebral infarction Diseases 0.000 abstract 1
- 208000013677 cerebrovascular dementia Diseases 0.000 abstract 1
- 201000010849 intracranial embolism Diseases 0.000 abstract 1
- 210000002330 subarachnoid space Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
- A61K38/1866—Vascular endothelial growth factor [VEGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP26702499 | 1999-09-21 | ||
| JP2000241205 | 2000-08-09 | ||
| PCT/JP2000/006347 WO2001021214A1 (en) | 1999-09-21 | 2000-09-18 | Gene therapy for cerebrovascular disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE468863T1 true ATE468863T1 (de) | 2010-06-15 |
Family
ID=26547690
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00961050T ATE468863T1 (de) | 1999-09-21 | 2000-09-18 | Gentherapie für zerebrale gefässerkrankungen |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6936594B1 (de) |
| EP (1) | EP1132098B1 (de) |
| JP (1) | JP4642303B2 (de) |
| KR (1) | KR100768023B1 (de) |
| CN (1) | CN1194762C (de) |
| AT (1) | ATE468863T1 (de) |
| AU (1) | AU774990B2 (de) |
| CA (1) | CA2348906A1 (de) |
| DE (1) | DE60044453D1 (de) |
| HK (1) | HK1042645A1 (de) |
| TW (1) | TWI250875B (de) |
| WO (1) | WO2001021214A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2230819C (en) * | 1995-08-29 | 2009-04-14 | Sumitomo Pharmaceuticals Co., Ltd. | Medicament comprising hgf gene |
| KR20010093804A (ko) | 1999-10-08 | 2001-10-29 | 무라야마 마사노리 | 심근증 유전자 치료 |
| US20020164310A1 (en) | 2001-03-02 | 2002-11-07 | Mgvs Ltd. | Nucleic acid constructs, cells transformed therewith and methods utilizing same for inducing liver regeneration and alleviation of portal hypertension |
| US7981863B2 (en) | 2001-09-19 | 2011-07-19 | Neuronova Ab | Treatment of Parkinson's disease with PDGF |
| AU2002349583B2 (en) * | 2001-11-28 | 2007-11-22 | Anges Mg, Inc. | Genetic remedies for neurodegenerative diseases |
| JP2003238439A (ja) * | 2002-02-13 | 2003-08-27 | Yasuhiko Tabata | 虚血治療剤 |
| EP1532987A4 (de) * | 2002-06-06 | 2005-12-28 | Anges Mg Inc | Mittel für die gentherapie bei zerebrovaskulären erkrankungen |
| US20080213348A1 (en) * | 2002-06-06 | 2008-09-04 | Anges Mg, Inc. | Agents for gene therapy of cerebrovascular disorders |
| CA2541603A1 (en) * | 2003-10-14 | 2005-04-21 | Kringle Pharma Inc. | Agent for improving mental disorders |
| JP4775940B2 (ja) * | 2004-06-29 | 2011-09-21 | アンジェスMg株式会社 | アロディニアの治療、改善、予防剤 |
| US20090082263A1 (en) * | 2004-07-29 | 2009-03-26 | Anges, Mg, Inc. | Drug and method for improving brain function |
| US20080025962A1 (en) * | 2004-11-30 | 2008-01-31 | Angesmg,Inc. | Remedy for Alzheimer's Disease |
| EP1863519B1 (de) * | 2005-03-31 | 2013-09-25 | The General Hospital Corporation | Modulation von hgf/hgfr-aktivität zur behandlung von lymphödem |
| US7977314B2 (en) | 2005-12-02 | 2011-07-12 | Amorfix Life Sciences Limited | Methods and compositions to treat and detect misfolded-SOD1 mediated diseases |
| WO2016069760A1 (en) * | 2014-10-31 | 2016-05-06 | Steven Yu | Method of treating dementia by intranasal administration of vegf gene therapy |
| WO2017210343A1 (en) * | 2016-06-01 | 2017-12-07 | The University Of Virginia Patent Foundation | Methods and compositions for modulating lymphatic vessels in the central nervous system |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4686085A (en) | 1980-04-14 | 1987-08-11 | Thomas Jefferson University | Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders |
| JPH0741429A (ja) * | 1993-07-30 | 1995-02-10 | Mitsubishi Chem Corp | 神経障害改善薬 |
| JP3680114B2 (ja) | 1993-09-17 | 2005-08-10 | 敏一 中村 | 脳神経障害治療剤 |
| US5652225A (en) * | 1994-10-04 | 1997-07-29 | St. Elizabeth's Medical Center Of Boston, Inc. | Methods and products for nucleic acid delivery |
| JPH08231416A (ja) * | 1995-02-24 | 1996-09-10 | Mitsubishi Chem Corp | 血栓症治療剤 |
| EA001616B1 (ru) * | 1995-02-28 | 2001-06-25 | Зе Риджентс Оф Зи Юнивесити Оф Кэлифоньэ | Способ лечения болезни сердца, способ лечения недостаточности периферических сосудов и способ ограничения доставки и экспрессии трансгенной конструкции в определенном органе или структуре |
| CA2230819C (en) * | 1995-08-29 | 2009-04-14 | Sumitomo Pharmaceuticals Co., Ltd. | Medicament comprising hgf gene |
| US5732654A (en) * | 1995-10-20 | 1998-03-31 | The First Republic Corporation Of America | Open air mariculture system and method of culturing marine animals |
| US6121246A (en) | 1995-10-20 | 2000-09-19 | St. Elizabeth's Medical Center Of Boston, Inc. | Method for treating ischemic tissue |
| WO1997030155A1 (en) * | 1996-02-15 | 1997-08-21 | Chiron Corporation | Gene therapy method using fgf-5 |
| CA2307953A1 (en) | 1997-10-27 | 1999-05-06 | Merck & Co., Inc. | Gene therapy for stimulation of angiogenesis |
| WO1999036103A1 (en) * | 1998-01-16 | 1999-07-22 | Mcgill University | Prevention and treatment of neuropathy by hepatocyte growth factor |
| JPH11246434A (ja) * | 1998-02-25 | 1999-09-14 | Sumitomo Pharmaceut Co Ltd | baxの低下及び/又はbcl−2の増加誘導剤 |
| US6199554B1 (en) * | 1998-03-27 | 2001-03-13 | The Brigham And Women's Hospital, Inc. | Method and apparatus for combining injury-mediated therapy and drug delivery |
-
2000
- 2000-09-18 EP EP00961050A patent/EP1132098B1/de not_active Expired - Lifetime
- 2000-09-18 DE DE60044453T patent/DE60044453D1/de not_active Expired - Lifetime
- 2000-09-18 KR KR1020017006211A patent/KR100768023B1/ko not_active Expired - Fee Related
- 2000-09-18 AU AU73148/00A patent/AU774990B2/en not_active Ceased
- 2000-09-18 CN CNB008020043A patent/CN1194762C/zh not_active Expired - Lifetime
- 2000-09-18 AT AT00961050T patent/ATE468863T1/de not_active IP Right Cessation
- 2000-09-18 US US09/856,374 patent/US6936594B1/en not_active Expired - Lifetime
- 2000-09-18 CA CA002348906A patent/CA2348906A1/en not_active Abandoned
- 2000-09-18 WO PCT/JP2000/006347 patent/WO2001021214A1/ja not_active Ceased
- 2000-09-18 HK HK02101912.1A patent/HK1042645A1/en unknown
- 2000-09-18 JP JP2001524637A patent/JP4642303B2/ja not_active Expired - Lifetime
- 2000-09-19 TW TW089119259A patent/TWI250875B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1132098A4 (de) | 2002-07-31 |
| KR20010089469A (ko) | 2001-10-06 |
| US6936594B1 (en) | 2005-08-30 |
| CN1322143A (zh) | 2001-11-14 |
| EP1132098B1 (de) | 2010-05-26 |
| TWI250875B (en) | 2006-03-11 |
| AU7314800A (en) | 2001-04-24 |
| JP4642303B2 (ja) | 2011-03-02 |
| DE60044453D1 (de) | 2010-07-08 |
| CN1194762C (zh) | 2005-03-30 |
| EP1132098A1 (de) | 2001-09-12 |
| AU774990B2 (en) | 2004-07-15 |
| KR100768023B1 (ko) | 2007-10-17 |
| HK1042645A1 (en) | 2002-08-23 |
| CA2348906A1 (en) | 2001-03-29 |
| WO2001021214A1 (en) | 2001-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |