ATE473743T1 - Arzneimittel und dessen herstellungsprozess - Google Patents

Arzneimittel und dessen herstellungsprozess

Info

Publication number: ATE473743T1
Authority: AT; Austria
Prior art keywords: dione; dihydrophthalazine; preparation; amino; nitro
Prior art date: 2000-03-28

Application number

AT01915966T

Other languages

English (en)

Inventor

Musa Tazhudinovich Abidov

Alexandr Petrovich Khokhlov

Original Assignee

Musa Tazhudinovich Abidov

Pavlov Anatoliy Ivanovich

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-03-28

Filing date

2001-02-28

Publication date

2010-07-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26654045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE473743(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2000-03-28 Priority claimed from RU2000107351A external-priority patent/RU2155043C1/ru

2000-08-01 Priority claimed from RU2000120270A external-priority patent/RU2163122C1/ru

2001-02-28 Application filed by Musa Tazhudinovich Abidov, Pavlov Anatoliy Ivanovich filed Critical Musa Tazhudinovich Abidov

2010-07-15 Application granted granted Critical

2010-07-15 Publication of ATE473743T1 publication Critical patent/ATE473743T1/de

Links

238000004519 manufacturing process Methods 0.000 title abstract 2
229940126601 medicinal product Drugs 0.000 title 1
238000002360 preparation method Methods 0.000 abstract 4
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
239000013067 intermediate product Substances 0.000 abstract 2
JKEBMURXLKGPLR-UHFFFAOYSA-N 5-amino-2,3-dihydrophthalazine-1,4-dione;sodium Chemical compound [Na].O=C1NNC(=O)C2=C1C(N)=CC=C2 JKEBMURXLKGPLR-UHFFFAOYSA-N 0.000 abstract 1
YVOBBFQJMOGQOU-UHFFFAOYSA-N 5-nitro-2,3-dihydrophthalazine-1,4-dione Chemical compound O=C1NNC(=O)C2=C1C([N+](=O)[O-])=CC=C2 YVOBBFQJMOGQOU-UHFFFAOYSA-N 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
230000003078 antioxidant effect Effects 0.000 abstract 1
239000007795 chemical reaction product Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000002519 immonomodulatory effect Effects 0.000 abstract 1
210000000987 immune system Anatomy 0.000 abstract 1
238000002955 isolation Methods 0.000 abstract 1
HWYHZTIRURJOHG-UHFFFAOYSA-N luminol Chemical compound O=C1NNC(=O)C2=C1C(N)=CC=C2 HWYHZTIRURJOHG-UHFFFAOYSA-N 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000047 product Substances 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Medicinal Preparation (AREA)

AT01915966T 2000-03-28 2001-02-28 Arzneimittel und dessen herstellungsprozess ATE473743T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
RU2000107351A RU2155043C1 (ru)	2000-03-28	2000-03-28	Способ получения лекарственного препарата
RU2000120270A RU2163122C1 (ru)	2000-08-01	2000-08-01	Лекарственное средство
PCT/RU2001/000086 WO2001072305A1 (en)	2000-03-28	2001-02-28	A medicament and method for the production thereof

Publications (1)

Publication Number	Publication Date
ATE473743T1 true ATE473743T1 (de)	2010-07-15

Family

ID=26654045

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01915966T ATE473743T1 (de)	2000-03-28	2001-02-28	Arzneimittel und dessen herstellungsprozess

Country Status (9)

Country	Link
US (1)	US6489326B1 (de)
EP (1)	EP1203587B1 (de)
AT (1)	ATE473743T1 (de)
AU (1)	AU4291201A (de)
BG (1)	BG106394A (de)
CZ (1)	CZ2002235A3 (de)
DE (1)	DE60142541D1 (de)
EA (1)	EA004056B1 (de)
WO (1)	WO2001072305A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2167659C1 (ru) *	2000-08-02	2001-05-27	Закрытое акционерное общество "Центр современной медицины "Медикор"	Способ коррекции иммунной системы живого организма
US7326690B2 (en) *	2002-10-30	2008-02-05	Bach Pharma, Inc.	Modulation of cell fates and activities by phthalazinediones
US8592421B2 (en)	2003-08-04	2013-11-26	Valery Khazhmuratovich Zhilov	Cyclic bioisosters of purine system derivatives and a pharmaceutical composition based thereon
RU2326870C2 (ru) *	2003-08-04	2008-06-20	Валерий Хажмуратович ЖИЛОВ	Применение циклических биоизостеров производных пуриновой системы для лечения расстройств, вызванных нарушениями нитрергической и дофаминергической систем
BRPI0307864B1 (pt) *	2003-11-25	2016-01-12	Univ Rio De Janeiro	processo para formação de hidrazidas a partir de hidrazinas e ácido dicarboxílicos
PL231885B1 (pl)	2009-01-16	2019-04-30	Abidopharma Spolka Z Ograniczona Odpowiedzialnoscia	Sposób wytwarzania soli 5-amino-2,3-dihydroftalazyno-1,4-di onu z metalami alkalicznymi, ich kompozycje farmaceutyczne i ich zastosowanie
EP2393361B1 (de) *	2009-02-06	2016-12-07	Bach Pharma, Inc.	Pharmazeutisch reine phthalazindione, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen
PT2542535E (pt)	2010-03-01	2014-08-25	Metriopharm Ag	Formas cristalinas para sal de sódio de 5-amino-2,3-di hidroftalazino-1,4-diona, preparações farmacêuticas contendo o mesmo e processo para a produção das ditas formas
WO2016096143A1 (de)	2014-12-18	2016-06-23	Metriopharm Ag	Kristalline form von 5-amino-2,3-dihydrophthalazin-1,4-dion natriumsalz, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung
RU2625267C1 (ru) *	2016-09-22	2017-07-12	Общество с ограниченной ответственностью "АБИДАФАРМА"	Способ производства нестерильных субстанций безводного "тамерита" и/или двухводного "галавита" - натриевых солей 5-амино-2,3-дигидрофталазин-1,4-диона (варианты) и способы дальнейшей их переработки в стерильные лекарственные препараты
US20210379063A1 (en) *	2018-10-26	2021-12-09	Immunopharma Plus D.O.O.	Oral aminodihydrophthalazinedione compositions and their use in the treatment of non-viral hepatitis
RU2747467C1 (ru) *	2020-07-17	2021-05-05	Муса Тажудинович Абидов	Способ защиты от коронавирусной инфекции

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SU130903A1 (ru) *	1959-11-21	1959-11-30	Е.П. Крысин	Способ получени 5-амино-2,3-дигидрофталазиндиона-1,4 (люминола)
GB1480591A (en) *	1973-10-31	1977-07-20	Boots Co Ltd	Substituted phthalazines and their use as therapeutic agents
US4226993A (en) *	1978-07-24	1980-10-07	Miles Laboratories, Inc.	Amino-functionalized phthalhydrazides
CH683965A5 (it)	1993-02-19	1994-06-30	Limad Marketing Exp & Imp	Composti della classe dei ftalidrazidici come sostanza attiva in agenti antinfiammatori ed antitossici.
CH683966A5 (it)	1993-02-19	1994-06-30	Limad Marketing Exp & Imp	Composti della classe dei ftalidrazidici come sostanze attive in agenti anti-ipossici e di difesa.
RU2113222C1 (ru) *	1997-09-30	1998-06-20	Закрытое акционерное общество "Центр современной медицины "Медикор"	Иммуномодулирующее средство
RU2138264C1 (ru)	1999-05-06	1999-09-27	Абидов Муса Тажудинович	Способ получения лекарственного препарата галавит
RU2155043C1 (ru) *	2000-03-28	2000-08-27	Абидов Муса Тажудинович	Способ получения лекарственного препарата
RU2167659C1 (ru) *	2000-08-02	2001-05-27	Закрытое акционерное общество "Центр современной медицины "Медикор"	Способ коррекции иммунной системы живого организма

2001
- 2001-02-28 EP EP01915966A patent/EP1203587B1/de not_active Revoked
- 2001-02-28 US US09/979,846 patent/US6489326B1/en not_active Expired - Lifetime
- 2001-02-28 WO PCT/RU2001/000086 patent/WO2001072305A1/ru not_active Ceased
- 2001-02-28 EA EA200101261A patent/EA004056B1/ru not_active IP Right Cessation
- 2001-02-28 AU AU42912/01A patent/AU4291201A/en not_active Abandoned
- 2001-02-28 CZ CZ2002235A patent/CZ2002235A3/cs unknown
- 2001-02-28 DE DE60142541T patent/DE60142541D1/de not_active Expired - Lifetime
- 2001-02-28 AT AT01915966T patent/ATE473743T1/de not_active IP Right Cessation
2002
- 2002-02-06 BG BG106394A patent/BG106394A/xx unknown

Also Published As

Publication number	Publication date
EP1203587B1 (de)	2010-07-14
US6489326B1 (en)	2002-12-03
EP1203587A4 (de)	2006-11-08
BG106394A (en)	2002-12-29
WO2001072305A1 (en)	2001-10-04
AU4291201A (en)	2001-10-08
EA200101261A1 (ru)	2002-06-27
EP1203587A1 (de)	2002-05-08
EA004056B1 (ru)	2003-12-25
CZ2002235A3 (cs)	2002-05-15
US20020198208A1 (en)	2002-12-26
DE60142541D1 (de)	2010-08-26

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Legal Events

Date	Code	Title	Description
2011-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties