ATE474064T1 - Probenaufbereitung zur genotypisierung mittels massenspektroskopie - Google Patents

Probenaufbereitung zur genotypisierung mittels massenspektroskopie

Info

Publication number
ATE474064T1
ATE474064T1 AT01954272T AT01954272T ATE474064T1 AT E474064 T1 ATE474064 T1 AT E474064T1 AT 01954272 T AT01954272 T AT 01954272T AT 01954272 T AT01954272 T AT 01954272T AT E474064 T1 ATE474064 T1 AT E474064T1
Authority
AT
Austria
Prior art keywords
genotyping
sample preparation
mass spectroscopy
mass spectrometry
products
Prior art date
Application number
AT01954272T
Other languages
English (en)
Inventor
Ivo Gut
Doris Lechner
Sascha Sauer
Original Assignee
Commissariat Energie Atomique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat Energie Atomique filed Critical Commissariat Energie Atomique
Application granted granted Critical
Publication of ATE474064T1 publication Critical patent/ATE474064T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
AT01954272T 2000-06-30 2001-06-29 Probenaufbereitung zur genotypisierung mittels massenspektroskopie ATE474064T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00401886A EP1170379A1 (de) 2000-06-30 2000-06-30 Erstellung von Proben zur Genotypisierung mittels Massenspektroskopie
PCT/IB2001/001439 WO2002000931A2 (en) 2000-06-30 2001-06-29 Sample generation for genotyping by mass spectrometry

Publications (1)

Publication Number Publication Date
ATE474064T1 true ATE474064T1 (de) 2010-07-15

Family

ID=8173746

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01954272T ATE474064T1 (de) 2000-06-30 2001-06-29 Probenaufbereitung zur genotypisierung mittels massenspektroskopie

Country Status (9)

Country Link
US (1) US20040038234A1 (de)
EP (2) EP1170379A1 (de)
AT (1) ATE474064T1 (de)
AU (1) AU2001276613A1 (de)
CA (1) CA2414585A1 (de)
DE (1) DE60142566D1 (de)
DK (1) DK1297181T3 (de)
ES (1) ES2347416T3 (de)
WO (1) WO2002000931A2 (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7534568B2 (en) * 1999-10-29 2009-05-19 Hologic Inc. Methods for detection of a target nucleic acid by forming a cleavage structure with a cleavage resistant probe
EP1364046B1 (de) * 2000-05-23 2011-11-30 Variagenics, Inc. Methode zur genetischen analyse von dna und zur detektion von sequenzvarianten
DE10108453B4 (de) * 2001-02-22 2005-10-20 Bruker Daltonik Gmbh Massenspektrometrische Mutationsanalyse mit photolytisch spaltbaren Primern
US7226739B2 (en) 2001-03-02 2007-06-05 Isis Pharmaceuticals, Inc Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations
US7666588B2 (en) * 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
US20040121309A1 (en) * 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in blood, bodily fluids, and bodily tissues
US7718354B2 (en) 2001-03-02 2010-05-18 Ibis Biosciences, Inc. Methods for rapid identification of pathogens in humans and animals
US20030027135A1 (en) * 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
WO2004060278A2 (en) 2002-12-06 2004-07-22 Isis Pharmaceuticals, Inc. Methods for rapid identification of pathogens in humans and animals
US8073627B2 (en) 2001-06-26 2011-12-06 Ibis Biosciences, Inc. System for indentification of pathogens
US7217510B2 (en) * 2001-06-26 2007-05-15 Isis Pharmaceuticals, Inc. Methods for providing bacterial bioagent characterizing information
US8046171B2 (en) * 2003-04-18 2011-10-25 Ibis Biosciences, Inc. Methods and apparatus for genetic evaluation
US8057993B2 (en) 2003-04-26 2011-11-15 Ibis Biosciences, Inc. Methods for identification of coronaviruses
US7964343B2 (en) * 2003-05-13 2011-06-21 Ibis Biosciences, Inc. Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8158354B2 (en) 2003-05-13 2012-04-17 Ibis Biosciences, Inc. Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US20100035239A1 (en) * 2003-09-11 2010-02-11 Isis Pharmaceuticals, Inc. Compositions for use in identification of bacteria
US20080138808A1 (en) * 2003-09-11 2008-06-12 Hall Thomas A Methods for identification of sepsis-causing bacteria
US8097416B2 (en) 2003-09-11 2012-01-17 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US20060240412A1 (en) * 2003-09-11 2006-10-26 Hall Thomas A Compositions for use in identification of adenoviruses
US8546082B2 (en) 2003-09-11 2013-10-01 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US20120122102A1 (en) 2003-09-11 2012-05-17 Rangarajan Sampath Compositions for use in identification of bacteria
US8163895B2 (en) 2003-12-05 2012-04-24 Ibis Biosciences, Inc. Compositions for use in identification of orthopoxviruses
US7666592B2 (en) 2004-02-18 2010-02-23 Ibis Biosciences, Inc. Methods for concurrent identification and quantification of an unknown bioagent
US8119336B2 (en) * 2004-03-03 2012-02-21 Ibis Biosciences, Inc. Compositions for use in identification of alphaviruses
WO2005113804A1 (en) * 2004-05-20 2005-12-01 Trillion Genomics Limited Use of mass labelled probes to detect target nucleic acids using mass spectrometry
JP4810533B2 (ja) 2004-05-24 2011-11-09 アイビス バイオサイエンシズ インコーポレイティッド ディジタルスレショルド化による選択的イオン濾過作用を用いた質量分光測定法
US20050266411A1 (en) * 2004-05-25 2005-12-01 Hofstadler Steven A Methods for rapid forensic analysis of mitochondrial DNA
US7811753B2 (en) 2004-07-14 2010-10-12 Ibis Biosciences, Inc. Methods for repairing degraded DNA
US8084207B2 (en) * 2005-03-03 2011-12-27 Ibis Bioscience, Inc. Compositions for use in identification of papillomavirus
US20060205040A1 (en) * 2005-03-03 2006-09-14 Rangarajan Sampath Compositions for use in identification of adventitious viruses
US8026084B2 (en) * 2005-07-21 2011-09-27 Ibis Biosciences, Inc. Methods for rapid identification and quantitation of nucleic acid variants
DE102006003415A1 (de) * 2006-01-24 2007-08-02 Siemens Ag Verfahren zur Analyse einer Probe
WO2008143627A2 (en) * 2006-09-14 2008-11-27 Ibis Biosciences, Inc. Targeted whole genome amplification method for identification of pathogens
JP5680304B2 (ja) * 2007-02-23 2015-03-04 アイビス バイオサイエンシズ インコーポレイティッド 迅速な法医学的dna分析法
WO2008118809A1 (en) * 2007-03-23 2008-10-02 Ibis Biosciences, Inc. Compositions for use in identification of mixed populations of bioagents
US9598724B2 (en) 2007-06-01 2017-03-21 Ibis Biosciences, Inc. Methods and compositions for multiple displacement amplification of nucleic acids
JP2009047956A (ja) * 2007-08-21 2009-03-05 Sony Corp 撮像装置
EP2344893B1 (de) 2008-09-16 2014-10-15 Ibis Biosciences, Inc. Mikroplatten-handhabungssysteme und verfahren
EP2347254A2 (de) 2008-09-16 2011-07-27 Ibis Biosciences, Inc. Probenverarbeitungseinheiten, -systeme und damit verbundene verfahren
EP2349549B1 (de) 2008-09-16 2012-07-18 Ibis Biosciences, Inc. Mischpatronen, mischstationen und verwandte ausrüstungen, und system
EP2396803A4 (de) 2009-02-12 2016-10-26 Ibis Biosciences Inc Ionisationssondenanordnungen
EP2233580A1 (de) 2009-03-05 2010-09-29 The Ohio State University Schnelle SNP-Genotypisierung
US8950604B2 (en) * 2009-07-17 2015-02-10 Ibis Biosciences, Inc. Lift and mount apparatus
WO2011008972A1 (en) 2009-07-17 2011-01-20 Ibis Biosciences, Inc. Systems for bioagent identification
US20110091882A1 (en) * 2009-10-02 2011-04-21 Ibis Biosciences, Inc. Determination of methylation status of polynucleotides
US9890408B2 (en) * 2009-10-15 2018-02-13 Ibis Biosciences, Inc. Multiple displacement amplification
NL2022038B1 (en) * 2018-11-21 2020-06-05 Biosparq B V Method for analysing an analyte sample and matrix material therefore

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5130538A (en) * 1989-05-19 1992-07-14 John B. Fenn Method of producing multiply charged ions and for determining molecular weights of molecules by use of the multiply charged ions of molecules
GB2236184B (en) * 1989-09-12 1993-07-28 Finnigan Mat Ltd Method of preparing samples for laser spectrometry analysis
US5605798A (en) * 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
JPH10509594A (ja) * 1994-11-28 1998-09-22 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 遺伝的多型の検出のための複合ミクロサテライトプライマー
GB9504598D0 (en) * 1995-03-03 1995-04-26 Imp Cancer Res Tech Method of nucleic acid analysis
US6004770A (en) * 1995-06-07 1999-12-21 Arizona State University Board Of Regents Sample presentation apparatus for mass spectrometry
PT840804E (pt) * 1996-01-23 2000-10-31 Qiagen Genomics Inc Metodos e composicoes para a analise de moleculas de acidos nocleicos usando tecnicas de separacao por dimensoes
US5885775A (en) * 1996-10-04 1999-03-23 Perseptive Biosystems, Inc. Methods for determining sequences information in polynucleotides using mass spectrometry
DE19824280B4 (de) * 1998-05-29 2004-08-19 Bruker Daltonik Gmbh Mutationsanalyse mittels Massenspektrometrie
US6703228B1 (en) * 1998-09-25 2004-03-09 Massachusetts Institute Of Technology Methods and products related to genotyping and DNA analysis
US6440705B1 (en) * 1998-10-01 2002-08-27 Vincent P. Stanton, Jr. Method for analyzing polynucleotides

Also Published As

Publication number Publication date
EP1297181B1 (de) 2010-07-14
ES2347416T3 (es) 2010-10-29
WO2002000931A2 (en) 2002-01-03
AU2001276613A1 (en) 2002-01-08
EP1170379A1 (de) 2002-01-09
EP1297181A2 (de) 2003-04-02
US20040038234A1 (en) 2004-02-26
DK1297181T3 (da) 2010-09-20
CA2414585A1 (en) 2002-01-03
WO2002000931A3 (en) 2002-05-23
DE60142566D1 (de) 2010-08-26

Similar Documents

Publication Publication Date Title
DE60142566D1 (de) Probenaufbereitung zur genotypisierung mittels massenspektroskopie
EP2088210A3 (de) Verbesserte Bisulfit-Umwandlung von DNA
DE60219132D1 (de) Mutationsanalyse Mittels PCR und Massenspektrometrie
DE69929542D1 (de) Komplexitätsmanagement und analyse genomischer dna
AU6163399A (en) Methods and products related to genotyping and dna analysis
WO2003027326A3 (en) Nucleic acid sequencing by raman monitoring of molecular deconstruction
DE60116651D1 (de) Methode zur amplifizierung und möglicher charakterisierung von nukleinsäuren
Fei et al. Analysis of single nucleotide polymorphisms by primer extension and matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry
WO2002072880A3 (de) Verfahren zum nachweis von cytosin-methylierungsmustern mit hoher sensitivität
EP1234888A3 (de) Mutationsanalyse nach Massenspektrometrie mit photolytically spaltbaren Primer
WO2003031649A3 (de) Verfahren zum nachweis von cytosin-methylierung in cpg-inseln
US20160298183A1 (en) High-throughput sequencing detection method for methylated cpg islands
WO2003057909A3 (de) Verfahren zum nachweis von cytosin-methylierungsmustern durch exponentielle ligation hybridisierter sondenoligonukleotide (mla)
EP1362929A3 (de) Methoden zur Genotypisierung
DE69940623D1 (de) Prozess zur Synthetisierung von Nukleinsäure
WO2003036434A3 (en) A system and method for consensus-calling with per-base quality values for sample assemblies
WO2003002760A3 (de) Verfahren zum nachweis von cytosin-methylierung durch vergleichende analyse der einzelstränge von amplifikaten
DE60122899D1 (de) Verfahren zur detektion von haplotypen mittels massenspektrometrie
Azhikina et al. Study of tissue-specific CpG methylation of DNA in extended genomic loci
WO2004067764A2 (en) Nucleic acid sequencing using nicking agents
Bus et al. Multiplex pyrosequencing of InDel markers for forensic DNA analysis
DE602004028281D1 (de) Verfahren zur hla-typisierung
WO2003002752A3 (en) Methods of using nick translate libraries for snp analysis
AU7703896A (en) Methods for separating and/or identifying dna molecules
WO2005003390A3 (en) Method for detection of mutations in dna

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties