ATE476433T1 - Tetomilast-polymorphe - Google Patents

Tetomilast-polymorphe

Info

Publication number: ATE476433T1
Authority: AT; Austria
Prior art keywords: tetomilast; polymorphs; tetomilast polymorphs
Prior art date: 2006-03-17

Application number

AT07739373T

Other languages

English (en)

Inventor

Satoshi Aoki

Kenji Nakaya

Masahiro Sota

Masashi Ishigami

Original Assignee

Otsuka Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-03-17

Filing date

2007-03-15

Publication date

2010-08-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38069222&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE476433(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2007-03-15 Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd

2010-08-15 Application granted granted Critical

2010-08-15 Publication of ATE476433T1 publication Critical patent/ATE476433T1/de

Links

XDBHURGONHZNJF-UHFFFAOYSA-N 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid Chemical compound C1=C(OCC)C(OCC)=CC=C1C1=NC(C=2N=C(C=CC=2)C(O)=O)=CS1 XDBHURGONHZNJF-UHFFFAOYSA-N 0.000 title 1
229950002896 tetomilast Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Pulmonology (AREA)
Oncology (AREA)
Physical Education & Sports Medicine (AREA)
Diabetes (AREA)
Cardiology (AREA)
Hematology (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Communicable Diseases (AREA)
Orthopedic Medicine & Surgery (AREA)
Dermatology (AREA)
Heart & Thoracic Surgery (AREA)
Toxicology (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Emergency Medicine (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Endocrinology (AREA)
Vascular Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Hospice & Palliative Care (AREA)
Transplantation (AREA)

AT07739373T 2006-03-17 2007-03-15 Tetomilast-polymorphe ATE476433T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2006075307		2006-03-17
PCT/JP2007/055931 WO2007119496A1 (en)	2006-03-17	2007-03-15	Tetomilast polymorphs

Publications (1)

Publication Number	Publication Date
ATE476433T1 true ATE476433T1 (de)	2010-08-15

Family

ID=38069222

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT07739373T ATE476433T1 (de)	2006-03-17	2007-03-15	Tetomilast-polymorphe

Country Status (26)

Country	Link
US (4)	US8501949B2 (de)
EP (4)	EP2311832B1 (de)
JP (2)	JP4182363B2 (de)
KR (6)	KR20110136902A (de)
CN (4)	CN101365697B (de)
AR (1)	AR059911A1 (de)
AT (1)	ATE476433T1 (de)
AU (1)	AU2007239906B2 (de)
BR (1)	BRPI0706224A2 (de)
CA (4)	CA2725698C (de)
CY (3)	CY1111046T1 (de)
DE (1)	DE602007008212D1 (de)
DK (3)	DK1999128T3 (de)
ES (3)	ES2348630T3 (de)
IL (4)	IL192237A (de)
MY (2)	MY151343A (de)
NO (1)	NO20083000L (de)
PH (1)	PH12015502374A1 (de)
PL (3)	PL2311832T3 (de)
PT (3)	PT2206711E (de)
RU (2)	RU2408597C2 (de)
SG (4)	SG172707A1 (de)
SI (3)	SI2311832T1 (de)
TW (1)	TWI394753B (de)
WO (1)	WO2007119496A1 (de)
ZA (2)	ZA200805235B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN117069780A (zh)	2016-10-06	2023-11-17	协和发酵生化株式会社	胞苷二磷酸胆碱的晶体及其制造方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CS216535B2 (en) *	1978-10-16	1982-11-26	Lilly Co Eli	Fungicide means and means for regulation of the water plants growth and method of making the active substances
JP3282731B2 (ja) *	1990-06-15	2002-05-20	メルクエンドカムパニーインコーポレーテッド	結晶の構造および大きさを改良する結晶化方法
DK0513387T3 (da)	1990-11-30	2000-06-05	Otsuka Pharma Co Ltd	Thiazolderivater som inhibitorer af aktivt oxygen
MY128323A (en) *	1996-09-30	2007-01-31	Otsuka Pharma Co Ltd	Thiazole derivatives for inhibition of cytokine production and of cell adhesion
JP4300373B2 (ja)	1996-09-30	2009-07-22	大塚製薬株式会社	サイトカイン産生抑制剤及び接着抑制剤
US6221153B1 (en) *	1998-06-09	2001-04-24	Trevor Percival Castor	Method for producing large crystals of complex molecules
SA99191255B1 (ar) *	1998-11-30	2006-11-25	جي دي سيرل اند كو	مركبات سيليكوكسيب celecoxib
GB9922963D0 (en) *	1999-09-28	1999-12-01	Pfizer Ltd	Polymorphic salt
JP4336913B2 (ja)	1999-02-12	2009-09-30	大塚製薬株式会社	アミド誘導体の製造方法
US6627646B2 (en) *	2001-07-17	2003-09-30	Sepracor Inc.	Norastemizole polymorphs
JP3713577B2 (ja)	2001-07-24	2005-11-09	大塚製薬株式会社	慢性閉塞性肺疾患治療薬
DK1411936T3 (da)	2001-07-24	2005-12-27	Otsuka Pharma Co Ltd	Anvendelse af thiazolderivater i fremstillingen af et medikament til behandling af kronisk obstruktiv lungesygdom
AR033485A1 (es) *	2001-09-25	2003-12-26	Otsuka Pharma Co Ltd	Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
PT1613598E (pt) *	2003-12-16	2012-01-13	Teva Pharma	Métodos para preparar formas cristalinas de aripiprazol

2007
- 2007-03-14 TW TW096108801A patent/TWI394753B/zh not_active IP Right Cessation
- 2007-03-15 RU RU2008127324/04A patent/RU2408597C2/ru not_active IP Right Cessation
- 2007-03-15 EP EP11152502A patent/EP2311832B1/de not_active Not-in-force
- 2007-03-15 KR KR1020117028260A patent/KR20110136902A/ko not_active Ceased
- 2007-03-15 CN CN2007800020022A patent/CN101365697B/zh not_active Expired - Fee Related
- 2007-03-15 PT PT10160007T patent/PT2206711E/pt unknown
- 2007-03-15 CA CA2725698A patent/CA2725698C/en not_active Expired - Fee Related
- 2007-03-15 SG SG2011043304A patent/SG172707A1/en unknown
- 2007-03-15 AU AU2007239906A patent/AU2007239906B2/en not_active Ceased
- 2007-03-15 EP EP10160007A patent/EP2206711B1/de not_active Not-in-force
- 2007-03-15 KR KR1020107025457A patent/KR101118943B1/ko not_active Expired - Fee Related
- 2007-03-15 AT AT07739373T patent/ATE476433T1/de active
- 2007-03-15 CA CA2725649A patent/CA2725649C/en not_active Expired - Fee Related
- 2007-03-15 ES ES07739373T patent/ES2348630T3/es active Active
- 2007-03-15 ES ES11152502T patent/ES2390957T3/es active Active
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- 2007-03-15 SI SI200731065T patent/SI2206711T1/sl unknown
- 2007-03-15 PL PL11152502T patent/PL2311832T3/pl unknown
- 2007-03-15 KR KR20127033350A patent/KR101482374B1/ko not_active Expired - Fee Related
- 2007-03-15 US US12/086,587 patent/US8501949B2/en not_active Expired - Fee Related
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- 2007-03-15 SG SG10201408225VA patent/SG10201408225VA/en unknown
- 2007-03-15 PL PL10160007T patent/PL2206711T3/pl unknown
- 2007-03-15 PT PT11152502T patent/PT2311832E/pt unknown
- 2007-03-15 EP EP11152503A patent/EP2311833A1/de not_active Withdrawn
- 2007-03-15 KR KR1020117016944A patent/KR101168630B1/ko not_active Expired - Fee Related
- 2007-03-15 PT PT07739373T patent/PT1999128E/pt unknown
- 2007-03-15 EP EP07739373A patent/EP1999128B1/de not_active Not-in-force
- 2007-03-15 PL PL07739373T patent/PL1999128T3/pl unknown
- 2007-03-15 MY MYPI20114235 patent/MY151343A/en unknown
- 2007-03-15 CA CA2634100A patent/CA2634100C/en not_active Expired - Fee Related
- 2007-03-15 KR KR1020117028259A patent/KR101252994B1/ko not_active Expired - Fee Related
- 2007-03-15 RU RU2009147223/04A patent/RU2441002C2/ru not_active IP Right Cessation
- 2007-03-15 MY MYPI20082153A patent/MY143808A/en unknown
- 2007-03-15 DK DK07739373.4T patent/DK1999128T3/da active
- 2007-03-15 DK DK11152502.8T patent/DK2311832T3/da active
- 2007-03-15 WO PCT/JP2007/055931 patent/WO2007119496A1/en not_active Ceased
- 2007-03-15 SI SI200730386T patent/SI1999128T1/sl unknown
- 2007-03-15 BR BRPI0706224-9A patent/BRPI0706224A2/pt not_active IP Right Cessation
- 2007-03-15 DE DE602007008212T patent/DE602007008212D1/de active Active
- 2007-03-15 CN CN201110065650.0A patent/CN102174044B/zh not_active Expired - Fee Related
- 2007-03-15 DK DK10160007.0T patent/DK2206711T3/da active
- 2007-03-15 CN CN2011100656708A patent/CN102174046B/zh not_active Expired - Fee Related
- 2007-03-15 CN CN2011100656661A patent/CN102174045A/zh active Pending
- 2007-03-15 ZA ZA200805235A patent/ZA200805235B/xx unknown
- 2007-03-15 KR KR1020087016527A patent/KR101083611B1/ko not_active Expired - Fee Related
- 2007-03-15 SG SG2011043296A patent/SG172706A1/en unknown
- 2007-03-15 ES ES10160007T patent/ES2390926T3/es active Active
- 2007-03-16 AR ARP070101070A patent/AR059911A1/es unknown
- 2007-03-19 JP JP2007069799A patent/JP4182363B2/ja not_active Expired - Fee Related
2008
- 2008-06-16 IL IL192237A patent/IL192237A/en unknown
- 2008-07-03 JP JP2008174664A patent/JP5197196B2/ja not_active Expired - Fee Related
- 2008-07-07 NO NO20083000A patent/NO20083000L/no not_active Application Discontinuation
2010
- 2010-03-09 ZA ZA2010/01687A patent/ZA201001687B/en unknown
- 2010-10-25 CY CY20101100965T patent/CY1111046T1/el unknown
2011
- 2011-07-21 IL IL214254A patent/IL214254A0/en unknown
- 2011-07-21 IL IL214253A patent/IL214253A/en not_active IP Right Cessation
- 2011-07-21 IL IL214252A patent/IL214252A0/en unknown
2012
- 2012-10-23 CY CY20121100996T patent/CY1113263T1/el unknown
- 2012-10-23 CY CY20121100994T patent/CY1113262T1/el unknown
2013
- 2013-03-04 US US13/784,652 patent/US8993601B2/en not_active Expired - Fee Related
- 2013-12-31 US US14/145,260 patent/US9145404B2/en not_active Expired - Fee Related
2015
- 2015-08-19 US US14/830,625 patent/US20150352095A1/en not_active Abandoned
- 2015-10-13 PH PH12015502374A patent/PH12015502374A1/en unknown

Also Published As

Publication number	Publication date
US8993601B2 (en)	2015-03-31
US20130184312A1 (en)	2013-07-18
CN102174044B (zh)	2014-02-26
HK1159079A1 (en)	2012-07-27
SG172706A1 (en)	2011-07-28
KR101118943B1 (ko)	2012-02-27
DK2311832T3 (da)	2012-10-08
AU2007239906B2 (en)	2010-07-29
DK2206711T3 (da)	2012-10-08
TW200813041A (en)	2008-03-16
IL192237A0 (en)	2009-02-11
CN102174046A (zh)	2011-09-07
CA2725810A1 (en)	2007-10-25
CN101365697A (zh)	2009-02-11
CA2725649C (en)	2013-05-14
SG10201408225VA (en)	2015-01-29
JP2008285498A (ja)	2008-11-27
AR059911A1 (es)	2008-05-07
EP2206711A3 (de)	2010-10-13
DK1999128T3 (da)	2010-11-08
EP2311832B1 (de)	2012-08-22
US20150352095A1 (en)	2015-12-10
PL1999128T3 (pl)	2010-12-31
CN101365697B (zh)	2011-11-23
KR20080077260A (ko)	2008-08-21
IL214254A0 (en)	2011-08-31
PT2206711E (pt)	2012-08-31
IL214253A (en)	2014-01-30
RU2009147223A (ru)	2011-06-27
CA2725698C (en)	2013-06-18
US9145404B2 (en)	2015-09-29
JP5197196B2 (ja)	2013-05-15
ES2348630T3 (es)	2010-12-10
KR101252994B1 (ko)	2013-04-15
IL214252A0 (en)	2011-08-31
KR20130003041A (ko)	2013-01-08
RU2441002C2 (ru)	2012-01-27
IL214253A0 (en)	2011-08-31
RU2408597C2 (ru)	2011-01-10
WO2007119496A1 (en)	2007-10-25
JP2007277235A (ja)	2007-10-25
DE602007008212D1 (de)	2010-09-16
SI1999128T1 (sl)	2010-12-31
MY143808A (en)	2011-07-15
PL2311832T3 (pl)	2013-01-31
CN102174046B (zh)	2013-12-25
CY1111046T1 (el)	2015-06-11
ZA201001687B (en)	2010-11-24
CA2634100A1 (en)	2007-10-25
SG172708A1 (en)	2011-07-28
KR20110087350A (ko)	2011-08-02
PT2311832E (pt)	2012-08-30
SG172707A1 (en)	2011-07-28
JP4182363B2 (ja)	2008-11-19
ES2390957T3 (es)	2012-11-20
CA2634100C (en)	2011-08-23
US20140113937A1 (en)	2014-04-24
CA2725649A1 (en)	2007-10-25
ES2390926T3 (es)	2012-11-19
EP2311833A1 (de)	2011-04-20
SI2206711T1 (sl)	2012-12-31
CN102174044A (zh)	2011-09-07
EP1999128A1 (de)	2008-12-10
PH12015502374A1 (en)	2017-03-22
CN102174045A (zh)	2011-09-07
KR20110136902A (ko)	2011-12-21
CA2725698A1 (en)	2007-10-25
NO20083000L (no)	2008-09-30
AU2007239906A1 (en)	2007-10-25
IL192237A (en)	2013-06-27
KR101083611B1 (ko)	2011-11-16
KR20110135427A (ko)	2011-12-16
US20100222590A1 (en)	2010-09-02
HK1124062A1 (en)	2009-07-03
PL2206711T3 (pl)	2013-01-31
EP1999128B1 (de)	2010-08-04
EP2206711A2 (de)	2010-07-14
SI2311832T1 (sl)	2012-12-31
PT1999128E (pt)	2011-01-20
CA2725810C (en)	2013-01-22
KR101168630B1 (ko)	2012-07-30
US8501949B2 (en)	2013-08-06
KR20100127886A (ko)	2010-12-06
KR101482374B1 (ko)	2015-01-14
CY1113263T1 (el)	2016-04-13
RU2008127324A (ru)	2010-01-10
HK1159080A1 (en)	2012-07-27
MY151343A (en)	2014-05-15
ZA200805235B (en)	2010-07-28
TWI394753B (zh)	2013-05-01
CY1113262T1 (el)	2016-04-13
EP2311832A1 (de)	2011-04-20
EP2206711B1 (de)	2012-08-22
BRPI0706224A2 (pt)	2011-03-22

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