ATE477335T1 - Verfahren zum nachweis von dna- einzelstrangbrüchen - Google Patents
Verfahren zum nachweis von dna- einzelstrangbrüchenInfo
- Publication number
- ATE477335T1 ATE477335T1 AT04700323T AT04700323T ATE477335T1 AT E477335 T1 ATE477335 T1 AT E477335T1 AT 04700323 T AT04700323 T AT 04700323T AT 04700323 T AT04700323 T AT 04700323T AT E477335 T1 ATE477335 T1 AT E477335T1
- Authority
- AT
- Austria
- Prior art keywords
- cell sample
- single strand
- strand breaks
- dna single
- detecting dna
- Prior art date
Links
- 210000003527 eukaryotic cell Anatomy 0.000 abstract 3
- VMGAPWLDMVPYIA-HIDZBRGKSA-N n'-amino-n-iminomethanimidamide Chemical compound N\N=C\N=N VMGAPWLDMVPYIA-HIDZBRGKSA-N 0.000 abstract 3
- BOLDJAUMGUJJKM-LSDHHAIUSA-N renifolin D Natural products CC(=C)[C@@H]1Cc2c(O)c(O)ccc2[C@H]1CC(=O)c3ccc(O)cc3O BOLDJAUMGUJJKM-LSDHHAIUSA-N 0.000 abstract 3
- 210000004027 cell Anatomy 0.000 abstract 2
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 abstract 2
- 230000005783 single-strand break Effects 0.000 abstract 2
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 2
- XJLXINKUBYWONI-DQQFMEOOSA-N [[(2r,3r,4r,5r)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2s,3r,4s,5s)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate Chemical compound NC(=O)C1=CC=C[N+]([C@@H]2[C@H]([C@@H](O)[C@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](OP(O)(O)=O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 XJLXINKUBYWONI-DQQFMEOOSA-N 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/337,012 US6913878B2 (en) | 2003-01-06 | 2003-01-06 | Method of detecting DNA single strand breaks |
| PCT/US2004/000068 WO2004063353A2 (en) | 2003-01-06 | 2004-01-06 | Method of detecting dna single strand breaks |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE477335T1 true ATE477335T1 (de) | 2010-08-15 |
Family
ID=32681143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04700323T ATE477335T1 (de) | 2003-01-06 | 2004-01-06 | Verfahren zum nachweis von dna- einzelstrangbrüchen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6913878B2 (de) |
| EP (1) | EP1581660B1 (de) |
| JP (1) | JP4558710B2 (de) |
| AT (1) | ATE477335T1 (de) |
| DE (1) | DE602004028569D1 (de) |
| WO (1) | WO2004063353A2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005023786A1 (ja) * | 2003-07-14 | 2005-03-17 | Dojindo Laboratories | 水溶性テトラゾリウム化合物 |
| WO2006076619A1 (en) * | 2005-01-14 | 2006-07-20 | Bayer Healthcare Llc | Water-soluble tetrazolium salts |
| CA2638750A1 (en) * | 2006-03-02 | 2007-09-13 | Laboratory Corporation Of America Holdings | Methods and systems for evaluating health risk factors by measurement of dna damage and dna repair |
| US7419209B1 (en) * | 2007-05-30 | 2008-09-02 | Lear Corporation | Seat assembly providing airflow path to cool batteries |
| GB2466816A (en) * | 2009-01-08 | 2010-07-14 | Ge Healthcare Ltd | High throughput DNA damage assay and separable multi-well plate apparatus |
| AU2010220755B2 (en) * | 2009-03-01 | 2013-08-22 | Ming Yu | Compounds, compositions and use for anticancer therapy |
| CN105418526B (zh) | 2015-11-09 | 2019-02-15 | 杭州伽玛生物科技有限公司 | 一类具有单磺酸苯基四氮唑结构的化合物及其应用 |
| CN116297435A (zh) * | 2023-05-15 | 2023-06-23 | 北京索莱宝科技有限公司 | 乙酰乙酸含量检测试剂盒、其使用方法和检测装置 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0675517B2 (ja) * | 1987-05-06 | 1994-09-28 | 株式会社トクヤマ | 還元型ニコチンアミド補酵素の定量方法 |
| US5185450A (en) * | 1991-02-19 | 1993-02-09 | University Of South Florida | Tetrazolium compounds for cell viability assays |
| JP2757348B2 (ja) * | 1996-04-18 | 1998-05-25 | 株式会社同仁化学研究所 | 新規水溶性テトラゾリウム塩化合物 |
| US7640334B2 (en) * | 2000-01-18 | 2009-12-29 | Frontrange Solutions | Network resource location detection probe apparatus and method |
-
2003
- 2003-01-06 US US10/337,012 patent/US6913878B2/en not_active Expired - Fee Related
-
2004
- 2004-01-06 EP EP04700323A patent/EP1581660B1/de not_active Expired - Lifetime
- 2004-01-06 DE DE602004028569T patent/DE602004028569D1/de not_active Expired - Lifetime
- 2004-01-06 WO PCT/US2004/000068 patent/WO2004063353A2/en not_active Ceased
- 2004-01-06 JP JP2006500778A patent/JP4558710B2/ja not_active Expired - Fee Related
- 2004-01-06 AT AT04700323T patent/ATE477335T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004063353A2 (en) | 2004-07-29 |
| JP4558710B2 (ja) | 2010-10-06 |
| EP1581660A2 (de) | 2005-10-05 |
| WO2004063353A3 (en) | 2004-12-29 |
| DE602004028569D1 (de) | 2010-09-23 |
| EP1581660A4 (de) | 2007-11-21 |
| US6913878B2 (en) | 2005-07-05 |
| EP1581660B1 (de) | 2010-08-11 |
| US20040132004A1 (en) | 2004-07-08 |
| JP2006517100A (ja) | 2006-07-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |