ATE47850T1 - 1-piperazinkarboxamid-derivate, verfahren zu ihrer herstellung und ihre verwendung in pharmazeutischen praeparaten. - Google Patents

1-piperazinkarboxamid-derivate, verfahren zu ihrer herstellung und ihre verwendung in pharmazeutischen praeparaten.

Info

Publication number: ATE47850T1
Authority: AT; Austria
Prior art keywords: hydrogen; different; derivatives; lower alkyl; same
Prior art date: 1983-08-10

Application number

AT84850237T

Other languages

English (en)

Inventor

Anders Karl Konrad Bjoerk

Knut Gunnar Olsson

Aina Lisbeth Abramo

Tomas Fex

Bengt Kenneth Rolan Gustafsson

Erik Gunnar Christensson

Original Assignee

Ferrosan Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-08-10

Filing date

1984-08-02

Publication date

1989-11-15

1984-08-02 Application filed by Ferrosan Ab filed Critical Ferrosan Ab

1989-11-15 Application granted granted Critical

1989-11-15 Publication of ATE47850T1 publication Critical patent/ATE47850T1/de

Links

238000000034 method Methods 0.000 title abstract 2
IVXQBCUBSIPQGU-UHFFFAOYSA-N piperazine-1-carboxamide Chemical class NC(=O)N1CCNCC1 IVXQBCUBSIPQGU-UHFFFAOYSA-N 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 6
239000001257 hydrogen Substances 0.000 abstract 6
125000000217 alkyl group Chemical group 0.000 abstract 5
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
241001465754 Metazoa Species 0.000 abstract 2
230000016571 aggressive behavior Effects 0.000 abstract 2
125000003342 alkenyl group Chemical group 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
230000001914 calming effect Effects 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
208000020016 psychiatric disease Diseases 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
239000011593 sulfur Substances 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/21—Radicals derived from sulfur analogues of carbonic acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)

AT84850237T 1983-08-10 1984-08-02 1-piperazinkarboxamid-derivate, verfahren zu ihrer herstellung und ihre verwendung in pharmazeutischen praeparaten. ATE47850T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE8304361A SE8304361D0 (sv)	1983-08-10	1983-08-10	Novel 1-acylpiperazine derivatives novel 1-acylpiperazine derivatives
EP84850237A EP0136274B1 (de)	1983-08-10	1984-08-02	1-Piperazinkarboxamid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung in pharmazeutischen Präparaten

Publications (1)

Publication Number	Publication Date
ATE47850T1 true ATE47850T1 (de)	1989-11-15

Family

ID=20352166

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT84850237T ATE47850T1 (de)	1983-08-10	1984-08-02	1-piperazinkarboxamid-derivate, verfahren zu ihrer herstellung und ihre verwendung in pharmazeutischen praeparaten.

Country Status (16)

Country	Link
US (1)	US4935419A (de)
EP (1)	EP0136274B1 (de)
JP (1)	JPH0723364B2 (de)
AT (1)	ATE47850T1 (de)
AU (1)	AU569537B2 (de)
CA (1)	CA1253148A (de)
DE (1)	DE3480395D1 (de)
DK (1)	DK157864C (de)
ES (3)	ES8705411A1 (de)
FI (1)	FI80449C (de)
HU (1)	HU196977B (de)
IE (1)	IE58065B1 (de)
IL (1)	IL72563A (de)
NZ (1)	NZ209166A (de)
SE (1)	SE8304361D0 (de)
WO (1)	WO1985000811A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE8500573D0 (sv) *	1985-02-08	1985-02-08	Ferrosan Ab	Novel piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain
GB8713240D0 (en) *	1987-06-05	1987-07-08	Proteus Biotech Ltd	Hormones
US5070089A (en) *	1988-01-26	1991-12-03	Nippon Chemiphar Co., Ltd.	Therapeutic agent for liver disease and piperazine derivatives
US5719156A (en) *	1995-05-02	1998-02-17	Schering Corporation	Piperazino derivatives as neurokinin antagonists
US5795894A (en) *	1995-05-02	1998-08-18	Schering Corporation	Piperazino derivatives as neurokinn antagonists
US5892039A (en) *	1995-08-31	1999-04-06	Schering Corporation	Piperazino derivatives as neurokinin antagonists
US5869488A (en) *	1996-05-01	1999-02-09	Schering Corporation	Piperazino derivatives as neurokinin antagonists
US5968929A (en) *	1996-10-30	1999-10-19	Schering Corporation	Piperazino derivatives as neurokinin antagonists
EP1158983A4 (de)	1999-03-03	2003-05-21	Merck & Co Inc	Inhibitoren der Prenyl-Protein Transferase
JP2012505906A (ja) *	2008-10-15	2012-03-08	日東電工株式会社	ポリグルタメートコンジュゲートの調製方法
JP2013514443A (ja) *	2009-12-16	2013-04-25	日東電工株式会社	ポリグルタミン酸の制御された合成
KR20140146192A (ko) *	2012-04-14	2014-12-24	인트라-셀룰라 써래피스, 인코퍼레이티드.	유기 화합물
PL3838274T3 (pl)	2016-01-26	2024-04-02	Intra-Cellular Therapies, Inc.	Pochodna pirydo[3',4':4,5]pirolo[1,2,3-DE]chinoksaliny do zastosowania w leczeniu zaburzeń OUN
WO2018126140A1 (en)	2016-12-29	2018-07-05	Intra-Cellular Therapies, Inc.	Organic compounds
EP3562484B1 (de)	2016-12-29	2021-08-25	Intra-Cellular Therapies, Inc.	Pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalinderivate zur behandlung von erkrankungen des zns
CN112040940A (zh)	2018-03-23	2020-12-04	细胞内治疗公司	有机化合物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3000892A (en) *	1959-11-16	1961-09-19	Paul A J Janssen	1-aroylalkyl-4-aroylpiperazines
GB1150245A (en) *	1966-03-04	1969-04-30	Chinoin Gyogyszer Es Vegyeszet	New Piperazine Derivatives and a Process for the Preparation thereof.
GB1143882A (de) *	1966-06-21
GB1186495A (en) *	1968-02-20	1970-04-02	Delalande Sa	0-[3-(4-Fluorobenzoyl) Proplyl]-4-Substituted Piperazines, their Acid Addition Salts and their method of preparation
FR2262521A1 (en) *	1973-08-08	1975-09-26	Delalande Sa	3-(3,4,5-Trimethoxyphenyl)piperazines - with coronary vasodilator, hypotensive, antiinflammatory, analgesic, and antiulcer activity
JPS5143772A (en) *	1974-09-26	1976-04-14	Kyorin Seiyaku Kk	11 * 33 fuenirupuropiru * 44 furoirupiperajinjudotaino seizoho
AR207031A1 (es) *	1974-03-06	1976-09-09	Kyorin Seiyaku Kk	Procedimiento para preparacion de nuevos derivados de 1-(3-fenilpropil)-4-furoilpiperacina
JPS50131974A (de) *	1974-03-06	1975-10-18
JPS518283A (en) *	1974-07-09	1976-01-23	Kyorin Seiyaku Kk	11 * 33 fuenirupuropiru * 44 karubamoirupiperajinjudotaino seizoho
JPS5346988A (en) *	1976-10-07	1978-04-27	Kyorin Seiyaku Kk	Piperadine derivative
NO154582C (no) *	1978-10-20	1986-11-05	Ferrosan Ab	Analogifremgangsmaate for fremstilling av terapeutisk aktive difenyl-dibutylpiperazinkarboksamider.
EP0042366B1 (de) *	1980-06-16	1984-11-07	AB Ferrosan	Diphenylbutyl-1-acylpiperazine
ATE28327T1 (de) *	1981-12-02	1987-08-15	Ferrosan Ab	1-piperazinocarboxylate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.

1983
- 1983-08-10 SE SE8304361A patent/SE8304361D0/xx unknown
1984
- 1984-08-01 IL IL72563A patent/IL72563A/xx not_active IP Right Cessation
- 1984-08-02 WO PCT/SE1984/000269 patent/WO1985000811A1/en not_active Ceased
- 1984-08-02 DE DE8484850237T patent/DE3480395D1/de not_active Expired
- 1984-08-02 JP JP59503010A patent/JPH0723364B2/ja not_active Expired - Lifetime
- 1984-08-02 AU AU32111/84A patent/AU569537B2/en not_active Expired
- 1984-08-02 EP EP84850237A patent/EP0136274B1/de not_active Expired
- 1984-08-02 HU HU843341A patent/HU196977B/hu unknown
- 1984-08-02 AT AT84850237T patent/ATE47850T1/de not_active IP Right Cessation
- 1984-08-09 ES ES535027A patent/ES8705411A1/es not_active Expired
- 1984-08-09 NZ NZ209166A patent/NZ209166A/en unknown
- 1984-08-09 IE IE205084A patent/IE58065B1/en not_active IP Right Cessation
- 1984-08-09 CA CA000460595A patent/CA1253148A/en not_active Expired
1985
- 1985-04-03 FI FI851350A patent/FI80449C/fi not_active IP Right Cessation
- 1985-04-09 DK DK157485A patent/DK157864C/da not_active IP Right Cessation
1986
- 1986-02-14 ES ES552001A patent/ES8704917A1/es not_active Expired
- 1986-08-01 ES ES556989A patent/ES8802039A1/es not_active Expired
1988
- 1988-07-29 US US07/227,420 patent/US4935419A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
IE58065B1 (en)	1993-06-30
ES8705411A1 (es)	1987-05-01
ES8802039A1 (es)	1988-03-16
HU196977B (en)	1989-02-28
DK157864C (da)	1990-07-23
JPH0723364B2 (ja)	1995-03-15
IL72563A0 (en)	1984-11-30
HUT37415A (en)	1985-12-28
IE842050L (en)	1985-02-10
CA1253148A (en)	1989-04-25
ES556989A0 (es)	1988-03-16
FI80449C (fi)	1990-06-11
FI851350L (fi)	1985-04-03
ES8704917A1 (es)	1987-04-16
IL72563A (en)	1988-10-31
ES535027A0 (es)	1987-05-01
DE3480395D1 (en)	1989-12-14
DK157864B (da)	1990-02-26
NZ209166A (en)	1987-07-31
FI80449B (fi)	1990-02-28
DK157485D0 (da)	1985-04-09
US4935419A (en)	1990-06-19
SE8304361D0 (sv)	1983-08-10
JPS60501956A (ja)	1985-11-14
FI851350A0 (fi)	1985-04-03
WO1985000811A1 (en)	1985-02-28
ES552001A0 (es)	1987-04-16
AU3211184A (en)	1985-03-12
DK157485A (da)	1985-04-09
EP0136274A1 (de)	1985-04-03
AU569537B2 (en)	1988-02-04
EP0136274B1 (de)	1989-11-08

Legal Events

Date	Code	Title
1990-04-15	UEP	Publication of translation of european patent specification
1997-05-15	EEIH	Change in the person of patent owner
2002-10-15	EEIH	Change in the person of patent owner
2004-11-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
ATE47850T1 (de)	1989-11-15	1-piperazinkarboxamid-derivate, verfahren zu ihrer herstellung und ihre verwendung in pharmazeutischen praeparaten.
HU9200065D0 (en)	1992-03-30	New phenyl-imidazolidines, process for producing them and process for preparing pharmaceutical preparatives containing said compounds
HUP9901652A2 (hu)	1999-09-28	Piperidin-karbonsav-származékok alkalmazása vérglükózkoncentráció csökkentésére alkalmas gyógyszerkészítmények előállítására
HU9301585D0 (en)	1993-09-28	Methods for producing phenyl-imidazolydine derivatives as well as medical preparatives containing said compounds
ATE60761T1 (de)	1991-02-15	Chinazolinderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DE3482039D1 (de)	1990-05-31	Benzofurancarboxamide, verfahren zu ihrer herstellung und pharmazeutische zubereitungen die sie enthalten.
ATE99315T1 (de)	1994-01-15	Platin(ii)-komplexe, verfahren zu ihrer herstellung und anwendung als antitumormittel.
DE3876813D1 (de)	1993-02-04	3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a.
MY131193A (en)	2007-07-31	7-(2-aminoethyl)-benzothiazolones
ES2083990T3 (es)	1996-05-01	Agentes antineoplasicos de quinolina triciclica.
ES8604960A1 (es)	1986-03-01	Procedimiento para preparar derivados de 1,6-naftiridina
ATE38665T1 (de)	1988-12-15	Verfahren zur herstellung von 5-perfluoralkyl-5,6-dihydrouracyl-derivaten und verwendbare zwischenprodukte.
ATE2044T1 (de)	1983-01-15	6h-1,2,4,6-thiatriazin-1,1-dioxide, herbizide, die diese verbindungen enthalten, ihre anwendung als herbizide und verfahren zu ihrer herstellung.
ATE24489T1 (de)	1987-01-15	Isoindolin-2-yl-amino-imidazoline und isoindolin- 2-yl-guanidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
AR246511A1 (es)	1994-08-31	Acido 2-azabiciclo (2.2.1)hept-5-eno-2-acetico y derivados del mismo, procedimiento para su preparacion y procedimiento para preparar n-fosfonometilglicina con los mismos.
ATE66226T1 (de)	1991-08-15	Tetrahydro-beta-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
RO86084B (ro)	1985-03-02	Procedeu pentru prepararea unor derivati ai 6, 6-dioxidului de oxazinobenzatiazina
CO4410157A1 (es)	1997-01-09	Una mezcla reguladora del crecimiento de las plantas que comprende cloruro de 1,1-dimetilpiperidina (mepiquat) y un derivado del acido ciclopropilmalonanilico
ES2040744T3 (es)	1993-11-01	Un procedimiento para preparar derivados de 1,2,4-triazinona.
ATE92074T1 (de)	1993-08-15	Beta-d-phenylthioxyloside, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ES2135383T3 (es)	1999-11-01	Pirido(3,4-b)pirrolo(1,2-e)(1,4,5)oxadiazepinas y compuestos analogos relacionados, un procedimiento para su preparacion y su uso como medicamentos.
ES483298A1 (es)	1980-09-01	Un procedimiento para la preparacion de derivados de benzo- diacepina
ATE36321T1 (de)	1988-08-15	(bis(substituiertes methyl)methyl>isochinolinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten.
ATE28457T1 (de)	1987-08-15	(5-(2-aminomethyl-imidazol-1-yl)-1,3-dialkyl-1h pyrazol-4-yl)(aryl)methanone und verfahren zu deren herstellung.