ATE479653T1 - Carboxyalkoxy-substituierte acyl-carboxyphenyl- harnstoffderivate, verfahren zu ihre herstellung und ihre verwendung als arzneimittel - Google Patents

Carboxyalkoxy-substituierte acyl-carboxyphenyl- harnstoffderivate, verfahren zu ihre herstellung und ihre verwendung als arzneimittel

Info

Publication number: ATE479653T1
Authority: AT; Austria
Prior art keywords: urea derivatives; carboxyalkoxy; alkyl; production; substituted acyl
Prior art date: 2002-10-04

Application number

AT03757879T

Other languages

English (en)

Inventor

Elisabeth Defossa

Dieter Kadereit

Thomas Klabunde

Hans-Joerg Burger

Andreas Herling

Karl-Ulrich Wendt

Reodern Erich Von

Karl Schoenafinger

Alfons Enhsen

Original Assignee

Sanofi Aventis Deutschland

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-10-04

Filing date

2003-09-22

Publication date

2010-09-15

2003-09-22 Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland

2010-09-15 Application granted granted Critical

2010-09-15 Publication of ATE479653T1 publication Critical patent/ATE479653T1/de

Links

229940126601 medicinal product Drugs 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 5
125000003545 alkoxy group Chemical group 0.000 abstract 3
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 2
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
125000004181 carboxyalkyl group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000003884 phenylalkyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
150000003672 ureas Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
- C07C275/48—Y being a hydrogen or a carbon atom
- C07C275/54—Y being a carbon atom of a six-membered aromatic ring, e.g. benzoylureas
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT03757879T 2002-10-04 2003-09-22 Carboxyalkoxy-substituierte acyl-carboxyphenyl- harnstoffderivate, verfahren zu ihre herstellung und ihre verwendung als arzneimittel ATE479653T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10246434A DE10246434B4 (de)	2002-10-04	2002-10-04	Carboxyalkoxy-substituierte Acyl-carboxyphenyl-harnstoffderivate und ihre Verwendung als Arzneimittel
PCT/EP2003/010501 WO2004033416A2 (de)	2002-10-04	2003-09-22	Carboxyalkoxy-substituierte acyl-carboxyphenyl-harnstoffderivate, verfahren zu ihre herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number	Publication Date
ATE479653T1 true ATE479653T1 (de)	2010-09-15

Family

ID=32010248

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03757879T ATE479653T1 (de)	2002-10-04	2003-09-22	Carboxyalkoxy-substituierte acyl-carboxyphenyl- harnstoffderivate, verfahren zu ihre herstellung und ihre verwendung als arzneimittel

Country Status (9)

Country	Link
EP (1)	EP1556339B1 (de)
JP (1)	JP4355290B2 (de)
AT (1)	ATE479653T1 (de)
AU (1)	AU2003273913A1 (de)
BR (1)	BR0314861A (de)
CA (1)	CA2500763A1 (de)
DE (2)	DE10246434B4 (de)
MX (1)	MXPA05003320A (de)
WO (1)	WO2004033416A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10306502B4 (de) *	2003-02-17	2005-03-17	Aventis Pharma Deutschland Gmbh	Substituierte 3-(Benzoylureido)-thiophenderivate und sie enthaltende Arzneimittel
PE20080251A1 (es)	2006-05-04	2008-04-25	Boehringer Ingelheim Int	Usos de inhibidores de dpp iv
EP2612669A4 (de)	2010-08-31	2014-05-14	Snu R&Db Foundation	Verwendung der fötalen neuprogrammierung eines ppar-agonisten

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE860511L (en) *	1985-03-01	1986-09-01	Alfa Farmaceutici Spa	"Benzoyl urea derivatives having anti-tumor activity"
GB9313268D0 (en) *	1993-06-28	1993-08-11	Zeneca Ltd	Chemical compounds
NZ523034A (en) *	2000-06-09	2004-07-30	Aventis Pharma Gmbh	Acylphenyl urea derivatives, methods for the production thereof and use thereof as a medicament

2002
- 2002-10-04 DE DE10246434A patent/DE10246434B4/de not_active Expired - Fee Related
2003
- 2003-09-22 JP JP2004542363A patent/JP4355290B2/ja not_active Expired - Fee Related
- 2003-09-22 MX MXPA05003320A patent/MXPA05003320A/es unknown
- 2003-09-22 BR BR0314861-0A patent/BR0314861A/pt not_active IP Right Cessation
- 2003-09-22 AT AT03757879T patent/ATE479653T1/de not_active IP Right Cessation
- 2003-09-22 DE DE50313047T patent/DE50313047D1/de not_active Expired - Lifetime
- 2003-09-22 AU AU2003273913A patent/AU2003273913A1/en not_active Abandoned
- 2003-09-22 WO PCT/EP2003/010501 patent/WO2004033416A2/de not_active Ceased
- 2003-09-22 CA CA002500763A patent/CA2500763A1/en not_active Abandoned
- 2003-09-22 EP EP03757879A patent/EP1556339B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
BR0314861A (pt)	2005-08-02
JP4355290B2 (ja)	2009-10-28
DE10246434B4 (de)	2005-08-04
MXPA05003320A (es)	2005-07-05
DE50313047D1 (de)	2010-10-14
WO2004033416A2 (de)	2004-04-22
CA2500763A1 (en)	2004-04-22
JP2006502206A (ja)	2006-01-19
EP1556339B1 (de)	2010-09-01
EP1556339A2 (de)	2005-07-27
AU2003273913A1 (en)	2004-05-04
WO2004033416A3 (de)	2004-05-13
DE10246434A1 (de)	2004-04-15

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Legal Events

Date	Code	Title	Description
2011-12-15	REN	Ceased due to non-payment of the annual fee