ATE485392T1 - Kassetten mit heterozyklischenfret-farbstoffen zur markierung biologischer moleküle und ihre verwendung beider sequenzierung von dna - Google Patents

Kassetten mit heterozyklischenfret-farbstoffen zur markierung biologischer moleküle und ihre verwendung beider sequenzierung von dna

Info

Publication number
ATE485392T1
ATE485392T1 AT03814207T AT03814207T ATE485392T1 AT E485392 T1 ATE485392 T1 AT E485392T1 AT 03814207 T AT03814207 T AT 03814207T AT 03814207 T AT03814207 T AT 03814207T AT E485392 T1 ATE485392 T1 AT E485392T1
Authority
AT
Austria
Prior art keywords
cassettes
heterocyclic
biological molecules
fret
sequencing dna
Prior art date
Application number
AT03814207T
Other languages
English (en)
Inventor
Satyam Nampalli
Weihong Zhang
Sudhakar Rao
Shiv Kumar
Original Assignee
Ge Healthcare Bio Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Bio Sciences filed Critical Ge Healthcare Bio Sciences
Application granted granted Critical
Publication of ATE485392T1 publication Critical patent/ATE485392T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/08—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
    • C09B23/083—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines five >CH- groups
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B11/00—Diaryl- or thriarylmethane dyes
    • C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
    • C09B11/06—Hydroxy derivatives of triarylmethanes in which at least one OH group is bound to an aryl nucleus and their ethers or esters
    • C09B11/08—Phthaleins; Phenolphthaleins; Fluorescein
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B11/00—Diaryl- or thriarylmethane dyes
    • C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
    • C09B11/10—Amino derivatives of triarylmethanes
    • C09B11/24—Phthaleins containing amino groups ; Phthalanes; Fluoranes; Phthalides; Rhodamine dyes; Phthaleins having heterocyclic aryl rings; Lactone or lactame forms of triarylmethane dyes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT03814207T 2002-12-20 2003-12-17 Kassetten mit heterozyklischenfret-farbstoffen zur markierung biologischer moleküle und ihre verwendung beider sequenzierung von dna ATE485392T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/326,039 US6855503B2 (en) 2002-12-20 2002-12-20 Heterocyclic FRETdye cassettes for labeling biological molecules and their use in DNA sequencing
PCT/US2003/040573 WO2004059011A1 (en) 2002-12-20 2003-12-17 Heterocyclic fret dye cassettes for labeling biological molecules and their use in dna sequencing

Publications (1)

Publication Number Publication Date
ATE485392T1 true ATE485392T1 (de) 2010-11-15

Family

ID=32654253

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03814207T ATE485392T1 (de) 2002-12-20 2003-12-17 Kassetten mit heterozyklischenfret-farbstoffen zur markierung biologischer moleküle und ihre verwendung beider sequenzierung von dna

Country Status (7)

Country Link
US (1) US6855503B2 (de)
EP (1) EP1573068B1 (de)
JP (1) JP2006511581A (de)
AT (1) ATE485392T1 (de)
AU (1) AU2003301116A1 (de)
DE (1) DE60334639D1 (de)
WO (1) WO2004059011A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7417726B2 (en) * 2003-09-19 2008-08-26 Applied Biosystems Inc. Normalization of data using controls
US20060029948A1 (en) * 2003-09-19 2006-02-09 Gary Lim Sealing cover and dye compatibility selection
US7570443B2 (en) 2003-09-19 2009-08-04 Applied Biosystems, Llc Optical camera alignment
US7169560B2 (en) * 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
WO2005077125A2 (en) * 2004-02-11 2005-08-25 Applera Corporation Methods and compositions for detecting nucleic acids
US20050255485A1 (en) * 2004-05-14 2005-11-17 Livak Kenneth J Detection of gene duplications
CA2581174A1 (en) 2004-09-16 2006-03-30 Applera Corporation Fluorescent dye compounds, conjugates and uses thereof
JP2008537155A (ja) * 2005-04-20 2008-09-11 ボード オブ リージェンツ ザ ユニバーシティー オブ テキサス システム 自動化タンパク質異常折り畳みの周期的増幅によるプリオンの超高感度検出
CN101189520A (zh) * 2005-05-03 2008-05-28 亚佩瑞股份有限公司 荧光检测系统和供其使用的染料组
JP4963015B2 (ja) * 2005-07-28 2012-06-27 学校法人日本大学 ヌクレオチド誘導体及びその利用
WO2008030973A2 (en) * 2006-09-06 2008-03-13 The Board Of Regents Of The University Of Texas System Methods and compositions for the detection of protein folding disorders
US20090253161A1 (en) * 2008-04-03 2009-10-08 Duke University Fluorescent prochelators for cellular iron detection
US9206979B2 (en) * 2011-03-10 2015-12-08 Air Products And Chemicals, Inc. Oxy-fuel burner arrangement
WO2016149537A1 (en) 2015-03-17 2016-09-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Bank vole prion protein as a broad-spectrum substrate for rt-quic-based detection and discrimination of prion strains
WO2018002015A1 (en) * 2016-06-28 2018-01-04 Ventana Medical Systems, Inc. New colors for chromogenic ihc and ish staining with multi-dye quinone methide and tyramide conjugates
EP4631529A3 (de) 2016-06-28 2026-03-11 Ventana Medical Systems, Inc. Anwendung von click-chemie zur signalverstärkung in ihc- und ish-tests
US11906530B2 (en) 2016-12-30 2024-02-20 The United States Of America, As Represented By The Secretary Department Of Health And Human Services Methods for the detection of tau protein aggregates
EP3692373A1 (de) 2017-10-02 2020-08-12 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Test zum nachweis von alpha-synuclein-impfaktivität in zusammenhang mit synucleinopathien

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6008373A (en) 1995-06-07 1999-12-28 Carnegie Mellon University Fluorescent labeling complexes with large stokes shift formed by coupling together cyanine and other fluorochromes capable of resonance energy transfer
US5863727A (en) 1996-05-03 1999-01-26 The Perkin-Elmer Corporation Energy transfer dyes with enhanced fluorescence
US5853992A (en) 1996-10-04 1998-12-29 The Regents Of The University Of California Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels

Also Published As

Publication number Publication date
WO2004059011A1 (en) 2004-07-15
JP2006511581A (ja) 2006-04-06
EP1573068A1 (de) 2005-09-14
EP1573068B1 (de) 2010-10-20
EP1573068A4 (de) 2006-01-04
DE60334639D1 (de) 2010-12-02
US20040126763A1 (en) 2004-07-01
AU2003301116A1 (en) 2004-07-22
US6855503B2 (en) 2005-02-15

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