ATE515698T1 - Nanopartikelsonden mit raman-spektroskopischen fingerabdrücken zum analytnachweis - Google Patents
Nanopartikelsonden mit raman-spektroskopischen fingerabdrücken zum analytnachweisInfo
- Publication number
- ATE515698T1 ATE515698T1 AT03736550T AT03736550T ATE515698T1 AT E515698 T1 ATE515698 T1 AT E515698T1 AT 03736550 T AT03736550 T AT 03736550T AT 03736550 T AT03736550 T AT 03736550T AT E515698 T1 ATE515698 T1 AT E515698T1
- Authority
- AT
- Austria
- Prior art keywords
- reagents
- raman
- specific binding
- probes
- detection
- Prior art date
Links
- 238000001069 Raman spectroscopy Methods 0.000 title abstract 5
- 238000001514 detection method Methods 0.000 title abstract 4
- 239000000523 sample Substances 0.000 title abstract 4
- 239000002105 nanoparticle Substances 0.000 title abstract 3
- 239000012491 analyte Substances 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 5
- 239000000975 dye Substances 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 3
- 230000009870 specific binding Effects 0.000 abstract 3
- 238000004416 surface enhanced Raman spectroscopy Methods 0.000 abstract 2
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 238000002493 microarray Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 102000054765 polymorphisms of proteins Human genes 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 abstract 1
- 229910052709 silver Inorganic materials 0.000 abstract 1
- 239000004332 silver Substances 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/587—Nanoparticles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/583—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Nanotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37853802P | 2002-05-07 | 2002-05-07 | |
| US38363002P | 2002-05-28 | 2002-05-28 | |
| US10/172,428 US20030211488A1 (en) | 2002-05-07 | 2002-06-14 | Nanoparticle probs with Raman spectrocopic fingerprints for analyte detection |
| PCT/US2003/014100 WO2003095973A2 (en) | 2002-05-07 | 2003-05-07 | Nanoparticle probes with raman spectroscopic fingerprints for analyte detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE515698T1 true ATE515698T1 (de) | 2011-07-15 |
Family
ID=29407691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03736550T ATE515698T1 (de) | 2002-05-07 | 2003-05-07 | Nanopartikelsonden mit raman-spektroskopischen fingerabdrücken zum analytnachweis |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20030211488A1 (de) |
| EP (1) | EP1499889B1 (de) |
| JP (1) | JP2005524849A (de) |
| AT (1) | ATE515698T1 (de) |
| AU (1) | AU2003237180B2 (de) |
| CA (1) | CA2483697C (de) |
| WO (1) | WO2003095973A2 (de) |
Families Citing this family (180)
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| US20030113740A1 (en) * | 2001-04-26 | 2003-06-19 | Mirkin Chad A. | Oligonucleotide-modified ROMP polymers and co-polymers |
| AU2002367709A1 (en) | 2001-04-26 | 2003-10-27 | Nanosphere, Inc. | Oligonucleotide-modified romp polymers and co-polymers |
| US7147687B2 (en) * | 2001-05-25 | 2006-12-12 | Nanosphere, Inc. | Non-alloying core shell nanoparticles |
| WO2002096262A2 (en) | 2001-05-25 | 2002-12-05 | Northwestern University | Non-alloying core shell nanoparticles |
| ATE423975T1 (de) * | 2001-08-03 | 2009-03-15 | Nanosphere Inc | Nanopartikelabbildungssystem und -verfahren |
| AU2002363062B2 (en) | 2001-10-09 | 2007-03-22 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| US7186814B2 (en) * | 2001-11-09 | 2007-03-06 | Nanosphere, Inc. | Bioconjugate-nanoparticle probes |
| US20030211488A1 (en) * | 2002-05-07 | 2003-11-13 | Northwestern University | Nanoparticle probs with Raman spectrocopic fingerprints for analyte detection |
| EP1540006B1 (de) * | 2002-07-02 | 2009-01-07 | Nanosphere, Inc. | Nanopartikel-polyanion-konjugate sowie verfahren zur verwendung davon beim nachweis von analyten |
| AU2003296014B2 (en) * | 2002-11-26 | 2010-06-03 | University Of Maryland Biotechnology Institute | High-sensitivity assays for pathogen detection using metal-enhanced fluorescence |
| CA2508359A1 (en) | 2002-12-12 | 2004-06-24 | Nanosphere, Inc. | Direct snp detection with unamplified dna |
| US7361410B2 (en) * | 2003-12-29 | 2008-04-22 | Intel Corporation | External modification of composite organic inorganic nanoclusters comprising raman active organic compound |
-
2002
- 2002-06-14 US US10/172,428 patent/US20030211488A1/en not_active Abandoned
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2003
- 2003-05-07 EP EP03736550A patent/EP1499889B1/de not_active Expired - Lifetime
- 2003-05-07 US US10/431,341 patent/US7985539B2/en not_active Expired - Fee Related
- 2003-05-07 JP JP2004503919A patent/JP2005524849A/ja active Pending
- 2003-05-07 WO PCT/US2003/014100 patent/WO2003095973A2/en not_active Ceased
- 2003-05-07 CA CA2483697A patent/CA2483697C/en not_active Expired - Fee Related
- 2003-05-07 AU AU2003237180A patent/AU2003237180B2/en not_active Ceased
- 2003-05-07 AT AT03736550T patent/ATE515698T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005524849A (ja) | 2005-08-18 |
| AU2003237180B2 (en) | 2007-05-24 |
| EP1499889B1 (de) | 2011-07-06 |
| AU2003237180A1 (en) | 2003-11-11 |
| EP1499889A2 (de) | 2005-01-26 |
| US7985539B2 (en) | 2011-07-26 |
| WO2003095973A2 (en) | 2003-11-20 |
| CA2483697A1 (en) | 2003-11-20 |
| WO2003095973A3 (en) | 2004-07-22 |
| EP1499889A4 (de) | 2006-11-08 |
| CA2483697C (en) | 2010-03-30 |
| US20040086897A1 (en) | 2004-05-06 |
| US20030211488A1 (en) | 2003-11-13 |
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