ATE490249T1 - Purinderivate als immunmodulatoren - Google Patents

Purinderivate als immunmodulatoren

Info

Publication number
ATE490249T1
ATE490249T1 AT08716859T AT08716859T ATE490249T1 AT E490249 T1 ATE490249 T1 AT E490249T1 AT 08716859 T AT08716859 T AT 08716859T AT 08716859 T AT08716859 T AT 08716859T AT E490249 T1 ATE490249 T1 AT E490249T1
Authority
AT
Austria
Prior art keywords
purine derivatives
immune modulators
modulators
immune
purine
Prior art date
Application number
AT08716859T
Other languages
English (en)
Inventor
Linos Lazarides
Stephen Smith
Richard Stocker
Colin Theobald
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Application granted granted Critical
Publication of ATE490249T1 publication Critical patent/ATE490249T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT08716859T 2007-02-19 2008-02-15 Purinderivate als immunmodulatoren ATE490249T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US89052307P 2007-02-19 2007-02-19
US97231307P 2007-09-14 2007-09-14
US2192108P 2008-01-18 2008-01-18
PCT/EP2008/051832 WO2008101867A1 (en) 2007-02-19 2008-02-15 Purine derivatives as immunomodulators

Publications (1)

Publication Number Publication Date
ATE490249T1 true ATE490249T1 (de) 2010-12-15

Family

ID=39473324

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08716859T ATE490249T1 (de) 2007-02-19 2008-02-15 Purinderivate als immunmodulatoren

Country Status (15)

Country Link
US (4) US20100120799A1 (de)
EP (1) EP2125792B1 (de)
JP (1) JP2010519186A (de)
AR (1) AR065372A1 (de)
AT (1) ATE490249T1 (de)
CL (1) CL2008000496A1 (de)
CY (1) CY1111281T1 (de)
DE (1) DE602008003764D1 (de)
DK (1) DK2125792T3 (de)
HR (1) HRP20110115T1 (de)
PL (1) PL2125792T3 (de)
PT (1) PT2125792E (de)
SI (1) SI2125792T1 (de)
TW (1) TW200843779A (de)
WO (1) WO2008101867A1 (de)

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JP5329444B2 (ja) * 2007-03-19 2013-10-30 アストラゼネカ・アクチエボラーグ Ｔｏｌｌ様受容体（ｔｌｒ７）モジュレーターとしての９−置換−８−オキソ−アデニン化合物
SI2132209T1 (sl) * 2007-03-19 2014-05-30 Astrazeneca Ab Spojine 9-substituiranega-8-okso-adenina, kot modulatorji Toll-like receptorja (TLR7)
EP2138497A4 (de) * 2007-03-20 2012-01-04 Dainippon Sumitomo Pharma Co Neue adeninverbindung
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Also Published As

Publication number Publication date
DK2125792T3 (da) 2011-03-07
AR065372A1 (es) 2009-06-03
US20100120799A1 (en) 2010-05-13
US20120283438A1 (en) 2012-11-08
US20090131458A1 (en) 2009-05-21
HRP20110115T1 (hr) 2011-03-31
US7977344B2 (en) 2011-07-12
CL2008000496A1 (es) 2008-09-22
DE602008003764D1 (de) 2011-01-13
US20110269781A1 (en) 2011-11-03
JP2010519186A (ja) 2010-06-03
PL2125792T3 (pl) 2011-05-31
SI2125792T1 (sl) 2011-03-31
CY1111281T1 (el) 2015-08-05
TW200843779A (en) 2008-11-16
EP2125792B1 (de) 2010-12-01
WO2008101867A1 (en) 2008-08-28
PT2125792E (pt) 2011-03-01
EP2125792A1 (de) 2009-12-02

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