ATE491722T1 - Herstellung und reinigung von il-29 - Google Patents
Herstellung und reinigung von il-29Info
- Publication number
- ATE491722T1 ATE491722T1 AT06816409T AT06816409T ATE491722T1 AT E491722 T1 ATE491722 T1 AT E491722T1 AT 06816409 T AT06816409 T AT 06816409T AT 06816409 T AT06816409 T AT 06816409T AT E491722 T1 ATE491722 T1 AT E491722T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- production
- purification
- coli
- vectors
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
- 241000588724 Escherichia coli Species 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 108091026890 Coding region Proteins 0.000 abstract 1
- 108020004705 Codon Proteins 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 238000011031 large-scale manufacturing process Methods 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Separation Of Suspended Particles By Flocculating Agents (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72354405P | 2005-10-04 | 2005-10-04 | |
| PCT/US2006/039139 WO2007041713A1 (en) | 2005-10-04 | 2006-10-04 | Production and purification of il-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE491722T1 true ATE491722T1 (de) | 2011-01-15 |
Family
ID=37603659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06816409T ATE491722T1 (de) | 2005-10-04 | 2006-10-04 | Herstellung und reinigung von il-29 |
Country Status (15)
| Country | Link |
|---|---|
| US (6) | US20080096252A1 (de) |
| EP (1) | EP1931704B1 (de) |
| JP (3) | JP5364375B2 (de) |
| AT (1) | ATE491722T1 (de) |
| AU (1) | AU2006299339B2 (de) |
| CA (1) | CA2625208A1 (de) |
| CY (1) | CY1112323T1 (de) |
| DE (1) | DE602006018969D1 (de) |
| DK (1) | DK1931704T3 (de) |
| ES (1) | ES2357152T3 (de) |
| IL (2) | IL189994A (de) |
| PL (1) | PL1931704T3 (de) |
| PT (1) | PT1931704E (de) |
| SI (1) | SI1931704T1 (de) |
| WO (1) | WO2007041713A1 (de) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2295450B1 (de) | 2000-09-29 | 2015-01-28 | Merck Sharp & Dohme Corp. | Pegyliertes interleukin 10 |
| US7038032B2 (en) | 2001-04-20 | 2006-05-02 | Zymogenetics, Inc. | Cytokine protein family |
| EP2251352A1 (de) * | 2003-08-07 | 2010-11-17 | ZymoGenetics, L.L.C. | Homogene Präparate von IL-28 und IL-29 |
| AU2006272937A1 (en) * | 2005-07-20 | 2007-02-01 | Bristol-Myers Squibb Company | Use of truncated cysteine IL28 and IL29 mutants to treat cancers and autoimmune disorders |
| EP1912668A2 (de) * | 2005-07-20 | 2008-04-23 | ZymoGenetics, Inc. | Il28- und il29-verkürzte cystein-mutanten und diese verwendende antivirale verfahren |
| CA2625208A1 (en) | 2005-10-04 | 2007-04-12 | Zymogenetics, Inc. | Production and purification of il-29 |
| AR067536A1 (es) * | 2007-07-17 | 2009-10-14 | Hoffmann La Roche | Metodo para obtener una eritropoyetina mono-pegilada en una forma sustancialmente homogenea |
| CL2008002053A1 (es) | 2007-07-17 | 2009-05-22 | Hoffmann La Roche | Metodo para la purificacion de una eritropoyetina monopeguilada (epompeg) que consiste en proporcionar una solucion que contiene eritropoyetina mono, poli y no peguilada y hacerla pasar por dos pasos de cromatografia de intercambio cationico y metodo para producir epo mpeg que incluye metodo de purificacion. |
| AU2008301229B2 (en) * | 2007-09-20 | 2013-10-10 | Australian Poultry Crc Pty Ltd | Novel avian cytokines and genetic sequences encoding same |
| KR20100103595A (ko) * | 2008-01-18 | 2010-09-27 | 에프. 호프만-라 로슈 아게 | 비-글라이코실화된 단백질의 정제 |
| AU2009255994B2 (en) * | 2008-06-05 | 2014-07-17 | Bristol-Myers Squibb Company | Use of pegylated Type III Interferons for the treatment of hepatitis C |
| JP5730211B2 (ja) | 2008-11-20 | 2015-06-03 | バイオジェン アイデック エムエー インコーポレイティドＢｉｏｇｅｎ Ｉｄｅｃ Ｉｎｃ． | ウイルスのアルギニン不活化 |
| ES2655364T3 (es) * | 2008-12-17 | 2018-02-19 | Merck Sharp & Dohme Corp. | Producción de IL-10 mono- y dipegilada y sus usos |
| EP2417246A4 (de) * | 2009-04-10 | 2015-11-04 | Reg Life Sciences Llc | Herstellung von fettsäurederivaten |
| US20120308517A1 (en) | 2010-02-09 | 2012-12-06 | Digna Biotech, S.L. | Compositions for the treatment of infectious and tumoural diseases |
| JP5768341B2 (ja) * | 2010-08-04 | 2015-08-26 | 東ソー株式会社 | Ｆｃ結合性タンパク質の製造方法 |
| CN102584979B (zh) * | 2011-01-18 | 2015-10-14 | 北京凯因科技股份有限公司 | PEG化干扰素λ |
| US10201584B1 (en) | 2011-05-17 | 2019-02-12 | Abbvie Inc. | Compositions and methods for treating HCV |
| CA2846092A1 (en) * | 2011-08-25 | 2013-02-28 | Nanogen Pharmaceutical Biotechnology | Peg-interferon lambda 1 conjugates |
| US8454947B1 (en) | 2012-03-01 | 2013-06-04 | Nanogen Pharmaceutical Biotechnology | PEG-interferon lambda 1 conjugates |
| RU2549710C2 (ru) * | 2012-06-29 | 2015-04-27 | Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) | Способ очистки рекомбинантного белка интерфероноподобного фактора iii типа |
| JP6086378B2 (ja) * | 2012-11-30 | 2017-03-01 | 国立大学法人お茶の水女子大学 | 組み換えヒト膵臓リパーゼの調製方法 |
| CN104045704B (zh) * | 2013-03-11 | 2016-08-10 | 中国医学科学院基础医学研究所 | PEG化重组人IFN-λ1、其制备方法和用途 |
| MX2015014438A (es) | 2013-04-18 | 2016-05-18 | Armo Biosciences Inc | Metodos de uso de interleucina-10 para tratar enfermedades y trastornos. |
| EP3010527B1 (de) | 2013-06-17 | 2018-08-08 | Armo Biosciences, Inc. | Verfahren zur beurteilung der proteinidentität und -stabilität |
| SG11201600380VA (en) * | 2013-07-19 | 2016-02-26 | Biogenomics Ltd | Apparatus for refolding of recombinant proteins |
| CN105658232A (zh) | 2013-08-30 | 2016-06-08 | 阿尔莫生物科技股份有限公司 | 使用白细胞介素-10治疗疾病和病症的方法 |
| CN120242030A (zh) | 2013-11-11 | 2025-07-04 | 阿尔莫生物科技股份有限公司 | 将白细胞介素-10用于治疗疾病和病症的方法 |
| CN109293782A (zh) * | 2014-01-08 | 2019-02-01 | 德益阳光生物技术（北京）有限责任公司 | 融合多肽及使用方法 |
| US11311519B2 (en) | 2014-05-01 | 2022-04-26 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
| US10076512B2 (en) | 2014-05-01 | 2018-09-18 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
| WO2015187295A2 (en) | 2014-06-02 | 2015-12-10 | Armo Biosciences, Inc. | Methods of lowering serum cholesterol |
| WO2016060996A2 (en) | 2014-10-14 | 2016-04-21 | Armo Biosciences, Inc. | Interleukin-15 compositions and uses thereof |
| AU2015336101A1 (en) | 2014-10-22 | 2017-04-20 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
| US20170362291A1 (en) * | 2014-12-23 | 2017-12-21 | Armo Biosciences, Inc. | Methods of Improving Yield in Recombinant Protein Production |
| WO2016126615A1 (en) | 2015-02-03 | 2016-08-11 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
| WO2016172342A1 (en) | 2015-04-21 | 2016-10-27 | Eiger Biopharmaceuticals, Inc. | Pharmaceutical compositions comprising lonafarnib and ritonavir |
| US20160361415A1 (en) | 2015-05-28 | 2016-12-15 | Armo Biosciences, Inc. | Methods of Using Interleukin-10 for Treating Diseases and Disorders |
| KR20180038553A (ko) | 2015-08-25 | 2018-04-16 | 아르모 바이오사이언시스 인코포레이티드 | 질환 및 장애를 치료하기 위한 인터류킨-10을 사용하는 방법 |
| JP7674628B2 (ja) | 2016-02-19 | 2025-05-12 | イーアイティー・ファーマ・インコーポレイテッド | インターフェロンラムダによるデルタ型肝炎ウイルス感染の処置 |
| CA3041533A1 (en) | 2016-11-07 | 2018-05-11 | Seattle Genetics, Inc. | Distribution of engineered-cysteine caps |
| EP3927733A4 (de) * | 2019-02-24 | 2022-07-06 | Oncosimis Biotech Private Limited | Verfahren zur kontinuierlichen herstellung von rekombinantem glp-1-peptid durch bakterien |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4795077A (en) * | 1988-05-23 | 1989-01-03 | Motorola Inc. | Bonding method and apparatus |
| EP0626448A3 (de) | 1993-05-26 | 1998-01-14 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Verfahren zur Herstellung und Reinigung von alpha-Interferon |
| EP1135493A2 (de) * | 1998-11-30 | 2001-09-26 | Eli Lilly And Company | Erythropoietische substanzen |
| CZ299516B6 (cs) * | 1999-07-02 | 2008-08-20 | F. Hoffmann-La Roche Ag | Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem |
| DE60135393D1 (de) * | 2000-06-30 | 2008-09-25 | Zymogenetics Inc | Allelische Variante des Interferon-ähnlichen Proteins Zcyto21 |
| US7038032B2 (en) * | 2001-04-20 | 2006-05-02 | Zymogenetics, Inc. | Cytokine protein family |
| CA2503305A1 (en) * | 2002-10-23 | 2004-05-06 | Zymogenetics, Inc. | Methods for treating viral infection using il-28 and il-29 |
| EP1573006B1 (de) * | 2002-12-13 | 2009-11-11 | ZymoGenetics, Inc. | Il-21-produktion in prokaryontischen wirten |
| EP2251352A1 (de) * | 2003-08-07 | 2010-11-17 | ZymoGenetics, L.L.C. | Homogene Präparate von IL-28 und IL-29 |
| JP4896005B2 (ja) * | 2004-04-02 | 2012-03-14 | ザイモジェネティクス リミテッド ライアビリティ カンパニー | Ｉｌ−２８およびｉｌ−２９システイン変異体を用いるウイルス感染を治療するための方法 |
| JP2008508310A (ja) * | 2004-07-29 | 2008-03-21 | ザイモジェネティクス， インコーポレイテッド | がんおよび自己免疫障害を治療するためのｉｌ−２８およびｉｌ−２９の使用法 |
| CN1305902C (zh) * | 2004-11-25 | 2007-03-21 | 汕头大学医学院 | 一种人白细胞介素29的生产方法及重组il－29工程菌 |
| AU2005314438B2 (en) * | 2004-12-10 | 2012-03-29 | Zymogenetics, Inc. | FGF18 production in prokaryotic hosts |
| AU2006272937A1 (en) * | 2005-07-20 | 2007-02-01 | Bristol-Myers Squibb Company | Use of truncated cysteine IL28 and IL29 mutants to treat cancers and autoimmune disorders |
| CA2625208A1 (en) | 2005-10-04 | 2007-04-12 | Zymogenetics, Inc. | Production and purification of il-29 |
-
2006
- 2006-10-04 CA CA002625208A patent/CA2625208A1/en not_active Abandoned
- 2006-10-04 DE DE602006018969T patent/DE602006018969D1/de active Active
- 2006-10-04 AT AT06816409T patent/ATE491722T1/de active
- 2006-10-04 JP JP2008534712A patent/JP5364375B2/ja active Active
- 2006-10-04 EP EP06816409A patent/EP1931704B1/de active Active
- 2006-10-04 SI SI200630952T patent/SI1931704T1/sl unknown
- 2006-10-04 US US11/538,688 patent/US20080096252A1/en not_active Abandoned
- 2006-10-04 WO PCT/US2006/039139 patent/WO2007041713A1/en not_active Ceased
- 2006-10-04 PT PT06816409T patent/PT1931704E/pt unknown
- 2006-10-04 AU AU2006299339A patent/AU2006299339B2/en active Active
- 2006-10-04 ES ES06816409T patent/ES2357152T3/es active Active
- 2006-10-04 DK DK06816409.4T patent/DK1931704T3/da active
- 2006-10-04 PL PL06816409T patent/PL1931704T3/pl unknown
-
2008
- 2008-03-06 IL IL189994A patent/IL189994A/en active IP Right Grant
-
2009
- 2009-08-07 US US12/537,935 patent/US7759092B2/en active Active
-
2010
- 2010-02-05 US US12/701,358 patent/US7968315B2/en active Active
-
2011
- 2011-03-11 CY CY20111100270T patent/CY1112323T1/el unknown
- 2011-05-24 US US13/114,566 patent/US8211670B2/en active Active
-
2012
- 2012-06-05 US US13/488,840 patent/US20120271037A1/en not_active Abandoned
- 2012-08-01 JP JP2012170709A patent/JP2012235789A/ja active Pending
- 2012-12-19 US US13/720,363 patent/US8759027B2/en active Active
- 2012-12-27 JP JP2012284581A patent/JP2013099337A/ja active Pending
-
2013
- 2013-07-29 IL IL227691A patent/IL227691A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1931704B1 (de) | 2010-12-15 |
| AU2006299339A1 (en) | 2007-04-12 |
| US8759027B2 (en) | 2014-06-24 |
| CA2625208A1 (en) | 2007-04-12 |
| JP5364375B2 (ja) | 2013-12-11 |
| US20120015403A1 (en) | 2012-01-19 |
| WO2007041713A1 (en) | 2007-04-12 |
| PT1931704E (pt) | 2011-03-28 |
| US20120271037A1 (en) | 2012-10-25 |
| DE602006018969D1 (de) | 2011-01-27 |
| IL227691A0 (en) | 2013-09-30 |
| AU2006299339B2 (en) | 2012-03-15 |
| JP2009510173A (ja) | 2009-03-12 |
| US20100003722A1 (en) | 2010-01-07 |
| IL189994A (en) | 2013-08-29 |
| CY1112323T1 (el) | 2015-12-09 |
| JP2012235789A (ja) | 2012-12-06 |
| IL189994A0 (en) | 2008-08-07 |
| ES2357152T3 (es) | 2011-04-19 |
| US20130143270A1 (en) | 2013-06-06 |
| JP2013099337A (ja) | 2013-05-23 |
| US8211670B2 (en) | 2012-07-03 |
| DK1931704T3 (da) | 2011-03-14 |
| EP1931704A1 (de) | 2008-06-18 |
| US7759092B2 (en) | 2010-07-20 |
| US20100222552A1 (en) | 2010-09-02 |
| US7968315B2 (en) | 2011-06-28 |
| US20080096252A1 (en) | 2008-04-24 |
| SI1931704T1 (sl) | 2011-04-29 |
| PL1931704T3 (pl) | 2011-06-30 |
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| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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