PL1931704T3 - Wytwarzanie i oczyszczanie IL-29 - Google Patents

Wytwarzanie i oczyszczanie IL-29

Info

Publication number
PL1931704T3
PL1931704T3 PL06816409T PL06816409T PL1931704T3 PL 1931704 T3 PL1931704 T3 PL 1931704T3 PL 06816409 T PL06816409 T PL 06816409T PL 06816409 T PL06816409 T PL 06816409T PL 1931704 T3 PL1931704 T3 PL 1931704T3
Authority
PL
Poland
Prior art keywords
methods
production
purification
coli
vectors
Prior art date
Application number
PL06816409T
Other languages
English (en)
Inventor
Bruce L Zamost
Geoffrey F Lee
Robert M Dedinsky
Original Assignee
Zymogenetics L L C
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics L L C, Bristol Myers Squibb Co filed Critical Zymogenetics L L C
Publication of PL1931704T3 publication Critical patent/PL1931704T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
PL06816409T 2005-10-04 2006-10-04 Wytwarzanie i oczyszczanie IL-29 PL1931704T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72354405P 2005-10-04 2005-10-04
PCT/US2006/039139 WO2007041713A1 (en) 2005-10-04 2006-10-04 Production and purification of il-29
EP06816409A EP1931704B1 (en) 2005-10-04 2006-10-04 Production and purification of il-29

Publications (1)

Publication Number Publication Date
PL1931704T3 true PL1931704T3 (pl) 2011-06-30

Family

ID=37603659

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06816409T PL1931704T3 (pl) 2005-10-04 2006-10-04 Wytwarzanie i oczyszczanie IL-29

Country Status (15)

Country Link
US (6) US20080096252A1 (pl)
EP (1) EP1931704B1 (pl)
JP (3) JP5364375B2 (pl)
AT (1) ATE491722T1 (pl)
AU (1) AU2006299339B2 (pl)
CA (1) CA2625208A1 (pl)
CY (1) CY1112323T1 (pl)
DE (1) DE602006018969D1 (pl)
DK (1) DK1931704T3 (pl)
ES (1) ES2357152T3 (pl)
IL (2) IL189994A (pl)
PL (1) PL1931704T3 (pl)
PT (1) PT1931704E (pl)
SI (1) SI1931704T1 (pl)
WO (1) WO2007041713A1 (pl)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2295450B1 (en) 2000-09-29 2015-01-28 Merck Sharp & Dohme Corp. Pegylated interleukin-10
US7038032B2 (en) 2001-04-20 2006-05-02 Zymogenetics, Inc. Cytokine protein family
EP2251352A1 (en) * 2003-08-07 2010-11-17 ZymoGenetics, L.L.C. Homogeneous preparations of IL-28 and IL-29
AU2006272937A1 (en) * 2005-07-20 2007-02-01 Bristol-Myers Squibb Company Use of truncated cysteine IL28 and IL29 mutants to treat cancers and autoimmune disorders
EP1912668A2 (en) * 2005-07-20 2008-04-23 ZymoGenetics, Inc. Il28 and il29 truncated cysteine mutants and antiviral methods of using same
CA2625208A1 (en) 2005-10-04 2007-04-12 Zymogenetics, Inc. Production and purification of il-29
AR067536A1 (es) * 2007-07-17 2009-10-14 Hoffmann La Roche Metodo para obtener una eritropoyetina mono-pegilada en una forma sustancialmente homogenea
CL2008002053A1 (es) 2007-07-17 2009-05-22 Hoffmann La Roche Metodo para la purificacion de una eritropoyetina monopeguilada (epompeg) que consiste en proporcionar una solucion que contiene eritropoyetina mono, poli y no peguilada y hacerla pasar por dos pasos de cromatografia de intercambio cationico y metodo para producir epo mpeg que incluye metodo de purificacion.
AU2008301229B2 (en) * 2007-09-20 2013-10-10 Australian Poultry Crc Pty Ltd Novel avian cytokines and genetic sequences encoding same
KR20100103595A (ko) * 2008-01-18 2010-09-27 에프. 호프만-라 로슈 아게 비-글라이코실화된 단백질의 정제
AU2009255994B2 (en) * 2008-06-05 2014-07-17 Bristol-Myers Squibb Company Use of pegylated Type III Interferons for the treatment of hepatitis C
JP5730211B2 (ja) 2008-11-20 2015-06-03 バイオジェン アイデック エムエー インコーポレイティドＢｉｏｇｅｎ Ｉｄｅｃ Ｉｎｃ． ウイルスのアルギニン不活化
ES2655364T3 (es) * 2008-12-17 2018-02-19 Merck Sharp & Dohme Corp. Producción de IL-10 mono- y dipegilada y sus usos
EP2417246A4 (en) * 2009-04-10 2015-11-04 Reg Life Sciences Llc PRODUCTION OF FATTY ACID DERIVATIVES
US20120308517A1 (en) 2010-02-09 2012-12-06 Digna Biotech, S.L. Compositions for the treatment of infectious and tumoural diseases
JP5768341B2 (ja) * 2010-08-04 2015-08-26 東ソー株式会社 Ｆｃ結合性タンパク質の製造方法
CN102584979B (zh) * 2011-01-18 2015-10-14 北京凯因科技股份有限公司 PEG化干扰素λ
US10201584B1 (en) 2011-05-17 2019-02-12 Abbvie Inc. Compositions and methods for treating HCV
CA2846092A1 (en) * 2011-08-25 2013-02-28 Nanogen Pharmaceutical Biotechnology Peg-interferon lambda 1 conjugates
US8454947B1 (en) 2012-03-01 2013-06-04 Nanogen Pharmaceutical Biotechnology PEG-interferon lambda 1 conjugates
RU2549710C2 (ru) * 2012-06-29 2015-04-27 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) Способ очистки рекомбинантного белка интерфероноподобного фактора iii типа
JP6086378B2 (ja) * 2012-11-30 2017-03-01 国立大学法人お茶の水女子大学 組み換えヒト膵臓リパーゼの調製方法
CN104045704B (zh) * 2013-03-11 2016-08-10 中国医学科学院基础医学研究所 PEG化重组人IFN-λ1、其制备方法和用途
MX2015014438A (es) 2013-04-18 2016-05-18 Armo Biosciences Inc Metodos de uso de interleucina-10 para tratar enfermedades y trastornos.
EP3010527B1 (en) 2013-06-17 2018-08-08 Armo Biosciences, Inc. Method for assessing protein identity and stability
SG11201600380VA (en) * 2013-07-19 2016-02-26 Biogenomics Ltd Apparatus for refolding of recombinant proteins
CN105658232A (zh) 2013-08-30 2016-06-08 阿尔莫生物科技股份有限公司 使用白细胞介素-10治疗疾病和病症的方法
CN120242030A (zh) 2013-11-11 2025-07-04 阿尔莫生物科技股份有限公司 将白细胞介素-10用于治疗疾病和病症的方法
CN109293782A (zh) * 2014-01-08 2019-02-01 德益阳光生物技术（北京）有限责任公司 融合多肽及使用方法
US11311519B2 (en) 2014-05-01 2022-04-26 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
US10076512B2 (en) 2014-05-01 2018-09-18 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
WO2015187295A2 (en) 2014-06-02 2015-12-10 Armo Biosciences, Inc. Methods of lowering serum cholesterol
WO2016060996A2 (en) 2014-10-14 2016-04-21 Armo Biosciences, Inc. Interleukin-15 compositions and uses thereof
AU2015336101A1 (en) 2014-10-22 2017-04-20 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
US20170362291A1 (en) * 2014-12-23 2017-12-21 Armo Biosciences, Inc. Methods of Improving Yield in Recombinant Protein Production
WO2016126615A1 (en) 2015-02-03 2016-08-11 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
WO2016172342A1 (en) 2015-04-21 2016-10-27 Eiger Biopharmaceuticals, Inc. Pharmaceutical compositions comprising lonafarnib and ritonavir
US20160361415A1 (en) 2015-05-28 2016-12-15 Armo Biosciences, Inc. Methods of Using Interleukin-10 for Treating Diseases and Disorders
KR20180038553A (ko) 2015-08-25 2018-04-16 아르모 바이오사이언시스 인코포레이티드 질환 및 장애를 치료하기 위한 인터류킨-10을 사용하는 방법
JP7674628B2 (ja) 2016-02-19 2025-05-12 イーアイティー・ファーマ・インコーポレイテッド インターフェロンラムダによるデルタ型肝炎ウイルス感染の処置
CA3041533A1 (en) 2016-11-07 2018-05-11 Seattle Genetics, Inc. Distribution of engineered-cysteine caps
EP3927733A4 (en) * 2019-02-24 2022-07-06 Oncosimis Biotech Private Limited PROCESS FOR THE CONTINUOUS PRODUCTION OF RECOMBINANT GLP-1 PEPTIDE BY BACTERIA

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4795077A (en) * 1988-05-23 1989-01-03 Motorola Inc. Bonding method and apparatus
EP0626448A3 (de) 1993-05-26 1998-01-14 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Verfahren zur Herstellung und Reinigung von alpha-Interferon
EP1135493A2 (en) * 1998-11-30 2001-09-26 Eli Lilly And Company Erythropoietic compounds
CZ299516B6 (cs) * 1999-07-02 2008-08-20 F. Hoffmann-La Roche Ag Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem
DE60135393D1 (de) * 2000-06-30 2008-09-25 Zymogenetics Inc Allelische Variante des Interferon-ähnlichen Proteins Zcyto21
US7038032B2 (en) * 2001-04-20 2006-05-02 Zymogenetics, Inc. Cytokine protein family
CA2503305A1 (en) * 2002-10-23 2004-05-06 Zymogenetics, Inc. Methods for treating viral infection using il-28 and il-29
EP1573006B1 (en) * 2002-12-13 2009-11-11 ZymoGenetics, Inc. Il-21 production in prokaryotic hosts
EP2251352A1 (en) * 2003-08-07 2010-11-17 ZymoGenetics, L.L.C. Homogeneous preparations of IL-28 and IL-29
JP4896005B2 (ja) * 2004-04-02 2012-03-14 ザイモジェネティクス リミテッド ライアビリティ カンパニー Ｉｌ−２８およびｉｌ−２９システイン変異体を用いるウイルス感染を治療するための方法
JP2008508310A (ja) * 2004-07-29 2008-03-21 ザイモジェネティクス， インコーポレイテッド がんおよび自己免疫障害を治療するためのｉｌ−２８およびｉｌ−２９の使用法
CN1305902C (zh) * 2004-11-25 2007-03-21 汕头大学医学院 一种人白细胞介素29的生产方法及重组il－29工程菌
AU2005314438B2 (en) * 2004-12-10 2012-03-29 Zymogenetics, Inc. FGF18 production in prokaryotic hosts
AU2006272937A1 (en) * 2005-07-20 2007-02-01 Bristol-Myers Squibb Company Use of truncated cysteine IL28 and IL29 mutants to treat cancers and autoimmune disorders
CA2625208A1 (en) 2005-10-04 2007-04-12 Zymogenetics, Inc. Production and purification of il-29

Also Published As

Publication number Publication date
EP1931704B1 (en) 2010-12-15
ATE491722T1 (de) 2011-01-15
AU2006299339A1 (en) 2007-04-12
US8759027B2 (en) 2014-06-24
CA2625208A1 (en) 2007-04-12
JP5364375B2 (ja) 2013-12-11
US20120015403A1 (en) 2012-01-19
WO2007041713A1 (en) 2007-04-12
PT1931704E (pt) 2011-03-28
US20120271037A1 (en) 2012-10-25
DE602006018969D1 (de) 2011-01-27
IL227691A0 (en) 2013-09-30
AU2006299339B2 (en) 2012-03-15
JP2009510173A (ja) 2009-03-12
US20100003722A1 (en) 2010-01-07
IL189994A (en) 2013-08-29
CY1112323T1 (el) 2015-12-09
JP2012235789A (ja) 2012-12-06
IL189994A0 (en) 2008-08-07
ES2357152T3 (es) 2011-04-19
US20130143270A1 (en) 2013-06-06
JP2013099337A (ja) 2013-05-23
US8211670B2 (en) 2012-07-03
DK1931704T3 (da) 2011-03-14
EP1931704A1 (en) 2008-06-18
US7759092B2 (en) 2010-07-20
US20100222552A1 (en) 2010-09-02
US7968315B2 (en) 2011-06-28
US20080096252A1 (en) 2008-04-24
SI1931704T1 (sl) 2011-04-29

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