ATE495164T1 - Thiadiazolderivate zur behandlung neurodegenerativer krankheiten - Google Patents
Thiadiazolderivate zur behandlung neurodegenerativer krankheitenInfo
- Publication number
- ATE495164T1 ATE495164T1 AT07846792T AT07846792T ATE495164T1 AT E495164 T1 ATE495164 T1 AT E495164T1 AT 07846792 T AT07846792 T AT 07846792T AT 07846792 T AT07846792 T AT 07846792T AT E495164 T1 ATE495164 T1 AT E495164T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- thiadiazole derivatives
- neurodegenerative diseases
- thiadiazole
- synucleopathy
- Prior art date
Links
- 208000015122 neurodegenerative disease Diseases 0.000 title 1
- 150000004867 thiadiazoles Chemical class 0.000 title 1
- YGTAZGSLCXNBQL-UHFFFAOYSA-N 1,2,4-thiadiazole Chemical class C=1N=CSN=1 YGTAZGSLCXNBQL-UHFFFAOYSA-N 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0623258.1A GB0623258D0 (en) | 2006-11-22 | 2006-11-22 | Thiadiazole derivatives for the treatment of neuro-degenerative diseases |
| PCT/EP2007/010192 WO2008061781A1 (en) | 2006-11-22 | 2007-11-22 | Thiadiazole derivatives for the treatment of neuro-degenerative diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE495164T1 true ATE495164T1 (de) | 2011-01-15 |
Family
ID=37636293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07846792T ATE495164T1 (de) | 2006-11-22 | 2007-11-22 | Thiadiazolderivate zur behandlung neurodegenerativer krankheiten |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7960556B2 (de) |
| EP (1) | EP2094677B1 (de) |
| AT (1) | ATE495164T1 (de) |
| DE (1) | DE602007011975D1 (de) |
| ES (1) | ES2359104T3 (de) |
| GB (1) | GB0623258D0 (de) |
| WO (1) | WO2008061781A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003078448A1 (en) | 2002-03-13 | 2003-09-25 | Signum Biosciences, Inc. | Modulation of protein methylation and phosphoprotein phosphate |
| US7923041B2 (en) | 2005-02-03 | 2011-04-12 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
| WO2006084033A1 (en) | 2005-02-03 | 2006-08-10 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
| US8536168B2 (en) * | 2007-03-15 | 2013-09-17 | Novartis Ag | Benzyl and pyridinyl derivatives as modulators of the hedgehog signaling pathway |
| CN102014897B (zh) | 2008-04-21 | 2015-08-05 | 西格纳姆生物科学公司 | 化合物、组合物和其制备方法 |
| JP5713352B2 (ja) * | 2008-06-27 | 2015-05-07 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ | チアジアゾリルオキシフェニルアミジン類及び殺菌剤としてのそれらの使用 |
| US20100041663A1 (en) | 2008-07-18 | 2010-02-18 | Novartis Ag | Organic Compounds as Smo Inhibitors |
| EP2163541A1 (de) * | 2008-09-12 | 2010-03-17 | Bayer Schering Pharma Aktiengesellschaft | Piperazin-Derivate zur Bindung und Abbildung von Amyloidplaques und deren Verwendung |
| GB201415569D0 (en) | 2014-09-03 | 2014-10-15 | C4X Discovery Ltd | Therapeutic Compounds |
| GB201601703D0 (en) | 2016-01-29 | 2016-03-16 | C4X Discovery Ltd | Therapeutic compounds |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5898085A (en) | 1997-03-28 | 1999-04-27 | E. I. Du Pont De Nemours And Company | Production of 1,3-diaminopentane by hydrogenation of 3-aminopentanenitrile |
| BR9906933A (pt) | 1998-01-16 | 2001-11-27 | Medivir Ab | Antiviróticos |
| US6060472A (en) | 1998-04-06 | 2000-05-09 | Apotex Inc. | Thiadiazole compounds useful as inhibitors of H+ /K+ atpase |
| BRPI0413709A (pt) | 2003-08-21 | 2006-10-17 | Pfizer Prod Inc | compostos para o tratamento de distúrbios neurodegenerativos |
| US7232820B2 (en) | 2004-04-01 | 2007-06-19 | Pfizer Inc | Thiadiazole-amine compounds for the treatment of neurodegenerative disorders |
| DE102004032567A1 (de) | 2004-07-05 | 2006-03-02 | Grünenthal GmbH | Substituierte 1-Propiolyl-piperazine |
| US7767677B2 (en) | 2004-09-20 | 2010-08-03 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
-
2006
- 2006-11-22 GB GBGB0623258.1A patent/GB0623258D0/en not_active Ceased
-
2007
- 2007-11-22 ES ES07846792T patent/ES2359104T3/es active Active
- 2007-11-22 DE DE602007011975T patent/DE602007011975D1/de active Active
- 2007-11-22 WO PCT/EP2007/010192 patent/WO2008061781A1/en not_active Ceased
- 2007-11-22 US US12/515,824 patent/US7960556B2/en not_active Expired - Fee Related
- 2007-11-22 EP EP07846792A patent/EP2094677B1/de not_active Not-in-force
- 2007-11-22 AT AT07846792T patent/ATE495164T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US20100144709A1 (en) | 2010-06-10 |
| EP2094677A1 (de) | 2009-09-02 |
| ES2359104T3 (es) | 2011-05-18 |
| EP2094677B1 (de) | 2011-01-12 |
| WO2008061781A1 (en) | 2008-05-29 |
| US7960556B2 (en) | 2011-06-14 |
| DE602007011975D1 (de) | 2011-02-24 |
| GB0623258D0 (en) | 2007-01-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |