ATE495179T1 - Tetrahydropyridothienpyrimidin-verbindungen und verwendung zur behandlung proliferativer erkrankungen - Google Patents
Tetrahydropyridothienpyrimidin-verbindungen und verwendung zur behandlung proliferativer erkrankungenInfo
- Publication number
- ATE495179T1 ATE495179T1 AT07753547T AT07753547T ATE495179T1 AT E495179 T1 ATE495179 T1 AT E495179T1 AT 07753547 T AT07753547 T AT 07753547T AT 07753547 T AT07753547 T AT 07753547T AT E495179 T1 ATE495179 T1 AT E495179T1
- Authority
- AT
- Austria
- Prior art keywords
- tetrahydropyridothienpyrimidine
- compounds
- treatment
- proliferative diseases
- proliferative
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000002062 proliferating effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78414606P | 2006-03-20 | 2006-03-20 | |
| PCT/US2007/006927 WO2007109279A2 (en) | 2006-03-20 | 2007-03-20 | Tetrahydropyridothienopyrimidine compounds and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE495179T1 true ATE495179T1 (de) | 2011-01-15 |
Family
ID=38523058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07753547T ATE495179T1 (de) | 2006-03-20 | 2007-03-20 | Tetrahydropyridothienpyrimidin-verbindungen und verwendung zur behandlung proliferativer erkrankungen |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US8501755B2 (de) |
| EP (1) | EP2001890B1 (de) |
| JP (1) | JP5282026B2 (de) |
| KR (1) | KR20080110834A (de) |
| CN (1) | CN101448840B (de) |
| AR (1) | AR059901A1 (de) |
| AT (1) | ATE495179T1 (de) |
| AU (1) | AU2007227317A1 (de) |
| BR (1) | BRPI0711045A2 (de) |
| CA (1) | CA2647036C (de) |
| CR (1) | CR10304A (de) |
| DE (1) | DE602007011906D1 (de) |
| DO (1) | DOP2007000053A (de) |
| EC (1) | ECSP088749A (de) |
| ES (1) | ES2357654T3 (de) |
| GT (1) | GT200800187A (de) |
| IL (1) | IL194028A0 (de) |
| MA (1) | MA30351B1 (de) |
| MX (1) | MX2008012006A (de) |
| NZ (1) | NZ571326A (de) |
| PA (1) | PA8719401A1 (de) |
| PE (1) | PE20080144A1 (de) |
| RU (1) | RU2008141239A (de) |
| SV (1) | SV2008003032A (de) |
| TN (1) | TNSN08370A1 (de) |
| TW (1) | TW200804397A (de) |
| UY (1) | UY30220A1 (de) |
| WO (1) | WO2007109279A2 (de) |
| ZA (1) | ZA200808017B (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7977359B2 (en) | 2005-11-04 | 2011-07-12 | Amira Pharmaceuticals, Inc. | 5-lipdxygenase-activating protein (FLAP) inhibitors |
| GB2431927B (en) | 2005-11-04 | 2010-03-17 | Amira Pharmaceuticals Inc | 5-Lipoxygenase-activating protein (FLAP) inhibitors |
| CA2699349C (en) * | 2007-09-14 | 2016-04-19 | Bayer Schering Pharma Aktiengesellschaft | Substituted tricyclic heterocyclic compounds for use as egfr inhibitors |
| WO2010054285A2 (en) | 2008-11-10 | 2010-05-14 | National Health Research Institutes | Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors |
| EP2806876A4 (de) * | 2012-01-25 | 2016-03-02 | Proteostasis Therapeutics Inc | Verbindungen zur erhöhung der proteasomaktivität |
| US20170107229A1 (en) * | 2014-05-26 | 2017-04-20 | Bayer Pharma Aktiengesellschaft | Substituted tetrahydropyridothienopyrimidines |
| US10561749B2 (en) | 2015-07-03 | 2020-02-18 | Kyoto University | Nuclear medicine diagnostic imaging agent |
| KR102474326B1 (ko) | 2016-06-22 | 2022-12-05 | 반더빌트유니버시티 | 무스카린성 아세틸콜린 수용체 m4의 양성 알로스테릭 조절제 |
| EP3534901B1 (de) | 2016-11-07 | 2022-06-22 | Vanderbilt University | Positive allosterische modulatoren des muskarinischen acetylcholinrezeptors m4 |
| EP3558309B1 (de) | 2016-11-07 | 2023-07-26 | Vanderbilt University | Positive allosterische modulatoren des muskarinischen acetylcholinrezeptors m4 |
| JP7097623B2 (ja) | 2016-11-07 | 2022-07-08 | ヴァンダービルト ユニヴァーシティ | ムスカリン性アセチルコリンレセプターｍ４のポジティブアロステリック調節因子 |
| WO2019113174A1 (en) | 2017-12-05 | 2019-06-13 | Vanderbilt University | Positive allosteric modulators of the muscarinic acetylcholine receptor m4 |
| TW201930311A (zh) | 2017-12-05 | 2019-08-01 | 泛德比爾特大學 | 蕈毒鹼型乙醯膽鹼受體m4之正向別構調節劑 |
| WO2020191151A1 (en) * | 2019-03-19 | 2020-09-24 | Oncovalent Therapeutics Inc. | Sumo inhibitor compounds and uses thereof |
| KR20240044458A (ko) * | 2021-08-05 | 2024-04-04 | 브리스톨-마이어스 스큅 컴퍼니 | Her2 억제제로서 사용하기 위한 트리시클릭 융합된 피리미딘 화합물 |
| CN114736154B (zh) * | 2022-03-15 | 2023-07-21 | 安庆朗坤药业有限公司 | N-（3-氯-4-（2-吡啶甲氧基）苯基）-2-氰基乙酰胺的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2365578A1 (en) * | 1999-03-30 | 2000-10-12 | Seiichi Uchida | Thienopyrimidine compounds and salts thereof and process for the preparation of the same |
| DE19944604A1 (de) * | 1999-09-17 | 2001-03-22 | Merck Patent Gmbh | Aminderivate |
| US6608053B2 (en) | 2000-04-27 | 2003-08-19 | Yamanouchi Pharmaceutical Co., Ltd. | Fused heteroaryl derivatives |
| JPWO2003035653A1 (ja) * | 2001-10-26 | 2005-02-10 | 日本曹達株式会社 | ピリドチエノピリミジン化合物およびその塩 |
| JP4712702B2 (ja) | 2003-07-24 | 2011-06-29 | バイエル・シエリング・フアーマ・アクチエンゲゼルシヤフト | 高増殖性疾患を処置するために有用な置換されたテトラヒドロベンゾチエノピリミジンアミン化合物 |
-
2007
- 2007-03-15 AR ARP070101057A patent/AR059901A1/es not_active Application Discontinuation
- 2007-03-19 TW TW096109309A patent/TW200804397A/zh unknown
- 2007-03-19 UY UY30220A patent/UY30220A1/es not_active Application Discontinuation
- 2007-03-19 PE PE2007000292A patent/PE20080144A1/es not_active Application Discontinuation
- 2007-03-20 JP JP2009501517A patent/JP5282026B2/ja not_active Expired - Fee Related
- 2007-03-20 RU RU2008141239/04A patent/RU2008141239A/ru not_active Application Discontinuation
- 2007-03-20 AU AU2007227317A patent/AU2007227317A1/en not_active Abandoned
- 2007-03-20 KR KR1020087025480A patent/KR20080110834A/ko not_active Ceased
- 2007-03-20 DO DO2007000053A patent/DOP2007000053A/es unknown
- 2007-03-20 AT AT07753547T patent/ATE495179T1/de not_active IP Right Cessation
- 2007-03-20 DE DE602007011906T patent/DE602007011906D1/de active Active
- 2007-03-20 BR BRPI0711045-6A patent/BRPI0711045A2/pt not_active IP Right Cessation
- 2007-03-20 CN CN2007800178021A patent/CN101448840B/zh not_active Expired - Fee Related
- 2007-03-20 EP EP07753547A patent/EP2001890B1/de not_active Not-in-force
- 2007-03-20 NZ NZ571326A patent/NZ571326A/en not_active IP Right Cessation
- 2007-03-20 ES ES07753547T patent/ES2357654T3/es active Active
- 2007-03-20 CA CA2647036A patent/CA2647036C/en not_active Expired - Fee Related
- 2007-03-20 PA PA20078719401A patent/PA8719401A1/es unknown
- 2007-03-20 MX MX2008012006A patent/MX2008012006A/es active IP Right Grant
- 2007-03-20 WO PCT/US2007/006927 patent/WO2007109279A2/en not_active Ceased
- 2007-03-20 US US12/225,285 patent/US8501755B2/en not_active Expired - Fee Related
-
2008
- 2008-09-11 IL IL194028A patent/IL194028A0/en unknown
- 2008-09-18 SV SV2008003032A patent/SV2008003032A/es not_active Application Discontinuation
- 2008-09-18 GT GT200800187A patent/GT200800187A/es unknown
- 2008-09-18 ZA ZA200808017A patent/ZA200808017B/xx unknown
- 2008-09-19 EC EC2008008749A patent/ECSP088749A/es unknown
- 2008-09-19 CR CR10304A patent/CR10304A/es not_active Application Discontinuation
- 2008-09-22 TN TNP2008000370A patent/TNSN08370A1/en unknown
- 2008-10-20 MA MA31320A patent/MA30351B1/fr unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |