DOP2007000053A - Compuestos de tetrahidropiridotienopirimidina y métodos para su empleo - Google Patents

Compuestos de tetrahidropiridotienopirimidina y métodos para su empleo

Info

Publication number
DOP2007000053A
DOP2007000053A DO2007000053A DO2007000053A DOP2007000053A DO P2007000053 A DOP2007000053 A DO P2007000053A DO 2007000053 A DO2007000053 A DO 2007000053A DO 2007000053 A DO2007000053 A DO 2007000053A DO P2007000053 A DOP2007000053 A DO P2007000053A
Authority
DO
Dominican Republic
Prior art keywords
methods
compounds
tetrahydropiridotienopirimidina
preparation
treatment
Prior art date
Application number
DO2007000053A
Other languages
English (en)
Inventor
Zheng Liu
Jason Newcom
Chengzhi Zhang
Kanwar Sidhu
Mario Lobell
Gaetan Ladouce
Qian Zhao
Kristen Allegue
Chetan P Darne
Original Assignee
Bayer Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharmaceuticals Corp filed Critical Bayer Pharmaceuticals Corp
Publication of DOP2007000053A publication Critical patent/DOP2007000053A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invencion se relaciona con novedosos compuestos y con procesos para su preparacion, con rnetodos para el tratamiento de enfermedades, en especial el cancer, que comprenden la administracion de dichos compuestos, y con metocos para la preparacion de composiciones farmaceuticas para el tratamiento 0 prevencion de trastornos, especialmente el cancer.
DO2007000053A 2006-03-20 2007-03-20 Compuestos de tetrahidropiridotienopirimidina y métodos para su empleo DOP2007000053A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78414606P 2006-03-20 2006-03-20

Publications (1)

Publication Number Publication Date
DOP2007000053A true DOP2007000053A (es) 2007-09-30

Family

ID=38523058

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2007000053A DOP2007000053A (es) 2006-03-20 2007-03-20 Compuestos de tetrahidropiridotienopirimidina y métodos para su empleo

Country Status (29)

Country Link
US (1) US8501755B2 (es)
EP (1) EP2001890B1 (es)
JP (1) JP5282026B2 (es)
KR (1) KR20080110834A (es)
CN (1) CN101448840B (es)
AR (1) AR059901A1 (es)
AT (1) ATE495179T1 (es)
AU (1) AU2007227317A1 (es)
BR (1) BRPI0711045A2 (es)
CA (1) CA2647036C (es)
CR (1) CR10304A (es)
DE (1) DE602007011906D1 (es)
DO (1) DOP2007000053A (es)
EC (1) ECSP088749A (es)
ES (1) ES2357654T3 (es)
GT (1) GT200800187A (es)
IL (1) IL194028A0 (es)
MA (1) MA30351B1 (es)
MX (1) MX2008012006A (es)
NZ (1) NZ571326A (es)
PA (1) PA8719401A1 (es)
PE (1) PE20080144A1 (es)
RU (1) RU2008141239A (es)
SV (1) SV2008003032A (es)
TN (1) TNSN08370A1 (es)
TW (1) TW200804397A (es)
UY (1) UY30220A1 (es)
WO (1) WO2007109279A2 (es)
ZA (1) ZA200808017B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
CA2699349C (en) * 2007-09-14 2016-04-19 Bayer Schering Pharma Aktiengesellschaft Substituted tricyclic heterocyclic compounds for use as egfr inhibitors
US8507502B2 (en) 2008-11-10 2013-08-13 National Health Research Institutes Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors
AU2013202373B2 (en) * 2012-01-25 2016-04-14 Proteostasis Therapeutics, Inc. Proteasome activity enhancing compounds
JP2017519737A (ja) * 2014-05-26 2017-07-20 バイエル・ファルマ・アクティエンゲゼルシャフト 置換テトラヒドロピリドチエノピリミジン
EP3111960B1 (en) * 2015-07-03 2019-12-11 Kyoto University Nuclear medicine diagnostic imaging agent
BR112018003417B1 (pt) 2016-06-22 2023-10-24 Vanderbilt University Composto modulador alostérico positivo do receptor muscarínico de acetilcolina m4 e composição farmacêutica que o compreende
EP3544961B1 (en) 2016-11-07 2021-08-18 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor m4
US10961253B2 (en) 2016-11-07 2021-03-30 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor M4
WO2018085803A1 (en) 2016-11-07 2018-05-11 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor m4
US11376254B2 (en) 2017-12-05 2022-07-05 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor M4
TW201930311A (zh) 2017-12-05 2019-08-01 泛德比爾特大學 蕈毒鹼型乙醯膽鹼受體m4之正向別構調節劑
US12398151B2 (en) 2019-03-19 2025-08-26 Suvalent Therapeutics, Inc. Sumo inhibitor compounds and uses thereof
US20240391931A1 (en) * 2021-08-05 2024-11-28 Bristol-Myers Squibb Company Tricyclic fused pyrimidine compounds for use as her2 inhibitors
CN114736154B (zh) * 2022-03-15 2023-07-21 安庆朗坤药业有限公司 N-（3-氯-4-（2-吡啶甲氧基）苯基）-2-氰基乙酰胺的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1346358A (zh) * 1999-03-30 2002-04-24 日本曹达株式会社 噻吩并嘧啶化合物及其盐和制备方法
DE19944604A1 (de) 1999-09-17 2001-03-22 Merck Patent Gmbh Aminderivate
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
JPWO2003035653A1 (ja) * 2001-10-26 2005-02-10 日本曹達株式会社 ピリドチエノピリミジン化合物およびその塩
ES2280040T3 (es) * 2003-07-24 2007-09-01 Bayer Pharmaceuticals Corporation Compuestos de tetrahidrobenzotienopirimidinamina sustituidos utiles para tratar trastornos hiperproliferativos.

Also Published As

Publication number Publication date
CA2647036C (en) 2015-06-23
KR20080110834A (ko) 2008-12-19
CN101448840A (zh) 2009-06-03
US20100298297A1 (en) 2010-11-25
CN101448840B (zh) 2011-12-14
EP2001890A2 (en) 2008-12-17
DE602007011906D1 (de) 2011-02-24
RU2008141239A (ru) 2010-04-27
TW200804397A (en) 2008-01-16
WO2007109279A3 (en) 2007-12-21
UY30220A1 (es) 2007-10-31
JP2009530387A (ja) 2009-08-27
GT200800187A (es) 2009-04-07
AR059901A1 (es) 2008-05-07
EP2001890B1 (en) 2011-01-12
WO2007109279A2 (en) 2007-09-27
ES2357654T3 (es) 2011-04-28
CR10304A (es) 2009-01-27
JP5282026B2 (ja) 2013-09-04
IL194028A0 (en) 2009-09-22
MA30351B1 (fr) 2009-04-01
US8501755B2 (en) 2013-08-06
ZA200808017B (en) 2009-11-25
TNSN08370A1 (en) 2009-12-29
NZ571326A (en) 2011-07-29
PE20080144A1 (es) 2008-04-06
ECSP088749A (es) 2008-10-31
MX2008012006A (es) 2008-10-03
PA8719401A1 (es) 2009-02-09
SV2008003032A (es) 2009-11-26
BRPI0711045A2 (pt) 2012-06-26
CA2647036A1 (en) 2007-09-27
AU2007227317A1 (en) 2007-09-27
ATE495179T1 (de) 2011-01-15

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