DOP2007000053A - Compuestos de tetrahidropiridotienopirimidina y métodos para su empleo - Google Patents

Compuestos de tetrahidropiridotienopirimidina y métodos para su empleo

Info

Publication number
DOP2007000053A
DOP2007000053A DO2007000053A DO2007000053A DOP2007000053A DO P2007000053 A DOP2007000053 A DO P2007000053A DO 2007000053 A DO2007000053 A DO 2007000053A DO 2007000053 A DO2007000053 A DO 2007000053A DO P2007000053 A DOP2007000053 A DO P2007000053A
Authority
DO
Dominican Republic
Prior art keywords
methods
compounds
tetrahydropiridotienopirimidina
preparation
treatment
Prior art date
Application number
DO2007000053A
Other languages
English (en)
Inventor
Zheng Liu
Jason Newcom
Chengzhi Zhang
Kanwar Sidhu
Mario Lobell
Gaetan Ladouce
Qian Zhao
Kristen Allegue
Chetan P Darne
Original Assignee
Bayer Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharmaceuticals Corp filed Critical Bayer Pharmaceuticals Corp
Publication of DOP2007000053A publication Critical patent/DOP2007000053A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invencion se relaciona con novedosos compuestos y con procesos para su preparacion, con rnetodos para el tratamiento de enfermedades, en especial el cancer, que comprenden la administracion de dichos compuestos, y con metocos para la preparacion de composiciones farmaceuticas para el tratamiento 0 prevencion de trastornos, especialmente el cancer.
DO2007000053A 2006-03-20 2007-03-20 Compuestos de tetrahidropiridotienopirimidina y métodos para su empleo DOP2007000053A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78414606P 2006-03-20 2006-03-20

Publications (1)

Publication Number Publication Date
DOP2007000053A true DOP2007000053A (es) 2007-09-30

Family

ID=38523058

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2007000053A DOP2007000053A (es) 2006-03-20 2007-03-20 Compuestos de tetrahidropiridotienopirimidina y métodos para su empleo

Country Status (29)

Country Link
US (1) US8501755B2 (es)
EP (1) EP2001890B1 (es)
JP (1) JP5282026B2 (es)
KR (1) KR20080110834A (es)
CN (1) CN101448840B (es)
AR (1) AR059901A1 (es)
AT (1) ATE495179T1 (es)
AU (1) AU2007227317A1 (es)
BR (1) BRPI0711045A2 (es)
CA (1) CA2647036C (es)
CR (1) CR10304A (es)
DE (1) DE602007011906D1 (es)
DO (1) DOP2007000053A (es)
EC (1) ECSP088749A (es)
ES (1) ES2357654T3 (es)
GT (1) GT200800187A (es)
IL (1) IL194028A0 (es)
MA (1) MA30351B1 (es)
MX (1) MX2008012006A (es)
NZ (1) NZ571326A (es)
PA (1) PA8719401A1 (es)
PE (1) PE20080144A1 (es)
RU (1) RU2008141239A (es)
SV (1) SV2008003032A (es)
TN (1) TNSN08370A1 (es)
TW (1) TW200804397A (es)
UY (1) UY30220A1 (es)
WO (1) WO2007109279A2 (es)
ZA (1) ZA200808017B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
EP2212332B1 (en) * 2007-09-14 2012-10-24 Bayer Intellectual Property GmbH Substituted tricyclic compounds and methods of use thereof
JP5781934B2 (ja) * 2008-11-10 2015-09-24 ナショナル ヘルス リサーチ インスティテューツ チロシンキナーゼ阻害剤としての融合２環および３環ピリミジン化合物
WO2013112699A2 (en) * 2012-01-25 2013-08-01 Proteostasis Therapeutics, Inc. Proteasome activity enhancing compounds
WO2015181063A1 (en) * 2014-05-26 2015-12-03 Bayer Pharma Aktiengesellschaft Substituted tetrahydropyridothienopyrimidines
US10561749B2 (en) 2015-07-03 2020-02-18 Kyoto University Nuclear medicine diagnostic imaging agent
BR112018003417B1 (pt) 2016-06-22 2023-10-24 Vanderbilt University Composto modulador alostérico positivo do receptor muscarínico de acetilcolina m4 e composição farmacêutica que o compreende
US11008335B2 (en) 2016-11-07 2021-05-18 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor M4
CN109862893B (zh) 2016-11-07 2023-02-17 范德比尔特大学 毒蕈碱型乙酰胆碱受体m4的正向别构调节剂
US10927126B2 (en) 2016-11-07 2021-02-23 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor M4
TW201930311A (zh) 2017-12-05 2019-08-01 泛德比爾特大學 蕈毒鹼型乙醯膽鹼受體m4之正向別構調節劑
JP2021505581A (ja) 2017-12-05 2021-02-18 ヴァンダービルト ユニヴァーシティ ムスカリン性アセチルコリンレセプターｍ４のポジティブアロステリック調節因子
EP3941905A1 (en) 2019-03-19 2022-01-26 Suvalent Therapeutics, Inc. Sumo inhibitor compounds and uses thereof
EP4380941A1 (en) * 2021-08-05 2024-06-12 Bristol-Myers Squibb Company Tricyclic fused pyrimidine compounds for use as her2 inhibitors
CN114736154B (zh) * 2022-03-15 2023-07-21 安庆朗坤药业有限公司 N-（3-氯-4-（2-吡啶甲氧基）苯基）-2-氰基乙酰胺的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1167367A4 (en) * 1999-03-30 2002-04-24 Nippon Soda Co THIENOPYRIMIDINE COMPOUNDS AND SALTS THEREOF, AND PROCESS FOR THE PREPARATION THEREOF
DE19944604A1 (de) 1999-09-17 2001-03-22 Merck Patent Gmbh Aminderivate
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
WO2003035653A1 (en) * 2001-10-26 2003-05-01 Nippon Soda Co.,Ltd. Pyridothienopyrimidine compound and salt thereof
CA2530281C (en) 2003-07-24 2013-02-12 Bayer Pharmaceuticals Corporation Substituted tetrahydrobenzothienopyrimidinamine compounds useful for treating hyper-proliferative disorders

Also Published As

Publication number Publication date
MA30351B1 (fr) 2009-04-01
GT200800187A (es) 2009-04-07
NZ571326A (en) 2011-07-29
PE20080144A1 (es) 2008-04-06
IL194028A0 (en) 2009-09-22
PA8719401A1 (es) 2009-02-09
CN101448840B (zh) 2011-12-14
JP5282026B2 (ja) 2013-09-04
SV2008003032A (es) 2009-11-26
MX2008012006A (es) 2008-10-03
EP2001890B1 (en) 2011-01-12
EP2001890A2 (en) 2008-12-17
RU2008141239A (ru) 2010-04-27
US8501755B2 (en) 2013-08-06
JP2009530387A (ja) 2009-08-27
CA2647036C (en) 2015-06-23
ZA200808017B (en) 2009-11-25
CA2647036A1 (en) 2007-09-27
CR10304A (es) 2009-01-27
BRPI0711045A2 (pt) 2012-06-26
KR20080110834A (ko) 2008-12-19
UY30220A1 (es) 2007-10-31
ES2357654T3 (es) 2011-04-28
WO2007109279A3 (en) 2007-12-21
AU2007227317A1 (en) 2007-09-27
TNSN08370A1 (en) 2009-12-29
AR059901A1 (es) 2008-05-07
WO2007109279A2 (en) 2007-09-27
US20100298297A1 (en) 2010-11-25
DE602007011906D1 (de) 2011-02-24
ECSP088749A (es) 2008-10-31
ATE495179T1 (de) 2011-01-15
TW200804397A (en) 2008-01-16
CN101448840A (zh) 2009-06-03

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