MA30351B1 - Composes de tetrahydropyridothienopyrimidine et leurs procedes d'utilisation - Google Patents
Composes de tetrahydropyridothienopyrimidine et leurs procedes d'utilisationInfo
- Publication number
- MA30351B1 MA30351B1 MA31320A MA31320A MA30351B1 MA 30351 B1 MA30351 B1 MA 30351B1 MA 31320 A MA31320 A MA 31320A MA 31320 A MA31320 A MA 31320A MA 30351 B1 MA30351 B1 MA 30351B1
- Authority
- MA
- Morocco
- Prior art keywords
- compounds
- methods
- tetrahydropyridothienopyrimidine
- pharmaceutical compositions
- variables
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 239000008194 pharmaceutical composition Substances 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention concerne un composé de la Formule (I), Dans laquelle les variables sont telles que divulgué dans le mémoire descriptif, des compositions pharmaceutiques contenant lesdits composés, des procédés de fabrication des composés et des compositions pharmaceutiques et des procédés d'utilisation des composés et des compositions pharmaceutiques pour le traitement ou la prévention d'affections, en particulier du cancer.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78414606P | 2006-03-20 | 2006-03-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA30351B1 true MA30351B1 (fr) | 2009-04-01 |
Family
ID=38523058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA31320A MA30351B1 (fr) | 2006-03-20 | 2008-10-20 | Composes de tetrahydropyridothienopyrimidine et leurs procedes d'utilisation |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US8501755B2 (fr) |
| EP (1) | EP2001890B1 (fr) |
| JP (1) | JP5282026B2 (fr) |
| KR (1) | KR20080110834A (fr) |
| CN (1) | CN101448840B (fr) |
| AR (1) | AR059901A1 (fr) |
| AT (1) | ATE495179T1 (fr) |
| AU (1) | AU2007227317A1 (fr) |
| BR (1) | BRPI0711045A2 (fr) |
| CA (1) | CA2647036C (fr) |
| CR (1) | CR10304A (fr) |
| DE (1) | DE602007011906D1 (fr) |
| DO (1) | DOP2007000053A (fr) |
| EC (1) | ECSP088749A (fr) |
| ES (1) | ES2357654T3 (fr) |
| GT (1) | GT200800187A (fr) |
| IL (1) | IL194028A0 (fr) |
| MA (1) | MA30351B1 (fr) |
| MX (1) | MX2008012006A (fr) |
| NZ (1) | NZ571326A (fr) |
| PA (1) | PA8719401A1 (fr) |
| PE (1) | PE20080144A1 (fr) |
| RU (1) | RU2008141239A (fr) |
| SV (1) | SV2008003032A (fr) |
| TN (1) | TNSN08370A1 (fr) |
| TW (1) | TW200804397A (fr) |
| UY (1) | UY30220A1 (fr) |
| WO (1) | WO2007109279A2 (fr) |
| ZA (1) | ZA200808017B (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7977359B2 (en) | 2005-11-04 | 2011-07-12 | Amira Pharmaceuticals, Inc. | 5-lipdxygenase-activating protein (FLAP) inhibitors |
| GB2431927B (en) | 2005-11-04 | 2010-03-17 | Amira Pharmaceuticals Inc | 5-Lipoxygenase-activating protein (FLAP) inhibitors |
| EP2212332B1 (fr) * | 2007-09-14 | 2012-10-24 | Bayer Intellectual Property GmbH | Composés tricycliques substitués et leurs procédés d'utilisation |
| JP5781934B2 (ja) * | 2008-11-10 | 2015-09-24 | ナショナル ヘルス リサーチ インスティテューツ | チロシンキナーゼ阻害剤としての融合２環および３環ピリミジン化合物 |
| WO2013112699A2 (fr) * | 2012-01-25 | 2013-08-01 | Proteostasis Therapeutics, Inc. | Composés renforçant l'activité des protéasomes |
| WO2015181063A1 (fr) * | 2014-05-26 | 2015-12-03 | Bayer Pharma Aktiengesellschaft | Tétrahydropyridothiénopyrimidinessubstituées |
| US10561749B2 (en) | 2015-07-03 | 2020-02-18 | Kyoto University | Nuclear medicine diagnostic imaging agent |
| BR112018003417B1 (pt) | 2016-06-22 | 2023-10-24 | Vanderbilt University | Composto modulador alostérico positivo do receptor muscarínico de acetilcolina m4 e composição farmacêutica que o compreende |
| US11008335B2 (en) | 2016-11-07 | 2021-05-18 | Vanderbilt University | Positive allosteric modulators of the muscarinic acetylcholine receptor M4 |
| CN109862893B (zh) | 2016-11-07 | 2023-02-17 | 范德比尔特大学 | 毒蕈碱型乙酰胆碱受体m4的正向别构调节剂 |
| US10927126B2 (en) | 2016-11-07 | 2021-02-23 | Vanderbilt University | Positive allosteric modulators of the muscarinic acetylcholine receptor M4 |
| TW201930311A (zh) | 2017-12-05 | 2019-08-01 | 泛德比爾特大學 | 蕈毒鹼型乙醯膽鹼受體m4之正向別構調節劑 |
| JP2021505581A (ja) | 2017-12-05 | 2021-02-18 | ヴァンダービルト ユニヴァーシティ | ムスカリン性アセチルコリンレセプターｍ４のポジティブアロステリック調節因子 |
| EP3941905A1 (fr) | 2019-03-19 | 2022-01-26 | Suvalent Therapeutics, Inc. | Composés inhibiteurs de sumo et leurs utilisations |
| EP4380941A1 (fr) * | 2021-08-05 | 2024-06-12 | Bristol-Myers Squibb Company | Composés pyrimidines fusionnés tricycliques destinés à être utilisés en tant qu'inhibiteurs de her2 |
| CN114736154B (zh) * | 2022-03-15 | 2023-07-21 | 安庆朗坤药业有限公司 | N-（3-氯-4-（2-吡啶甲氧基）苯基）-2-氰基乙酰胺的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1167367A4 (fr) * | 1999-03-30 | 2002-04-24 | Nippon Soda Co | Composes de thienopyrimidine et leurs sels, et procede de preparation desdits composes et sels |
| DE19944604A1 (de) | 1999-09-17 | 2001-03-22 | Merck Patent Gmbh | Aminderivate |
| US6608053B2 (en) * | 2000-04-27 | 2003-08-19 | Yamanouchi Pharmaceutical Co., Ltd. | Fused heteroaryl derivatives |
| WO2003035653A1 (fr) * | 2001-10-26 | 2003-05-01 | Nippon Soda Co.,Ltd. | Compose pyridothienopyrimidine et son sel |
| CA2530281C (fr) | 2003-07-24 | 2013-02-12 | Bayer Pharmaceuticals Corporation | Composes tetrahydrobenzothienopyrimidinamine a substitution utiles pour le traitement de troubles hyper-proliferatifs |
-
2007
- 2007-03-15 AR ARP070101057A patent/AR059901A1/es not_active Application Discontinuation
- 2007-03-19 PE PE2007000292A patent/PE20080144A1/es not_active Application Discontinuation
- 2007-03-19 TW TW096109309A patent/TW200804397A/zh unknown
- 2007-03-19 UY UY30220A patent/UY30220A1/es not_active Application Discontinuation
- 2007-03-20 ES ES07753547T patent/ES2357654T3/es active Active
- 2007-03-20 EP EP07753547A patent/EP2001890B1/fr not_active Not-in-force
- 2007-03-20 AT AT07753547T patent/ATE495179T1/de not_active IP Right Cessation
- 2007-03-20 BR BRPI0711045-6A patent/BRPI0711045A2/pt not_active IP Right Cessation
- 2007-03-20 KR KR1020087025480A patent/KR20080110834A/ko not_active Ceased
- 2007-03-20 WO PCT/US2007/006927 patent/WO2007109279A2/fr not_active Ceased
- 2007-03-20 AU AU2007227317A patent/AU2007227317A1/en not_active Abandoned
- 2007-03-20 CA CA2647036A patent/CA2647036C/fr not_active Expired - Fee Related
- 2007-03-20 DE DE602007011906T patent/DE602007011906D1/de active Active
- 2007-03-20 NZ NZ571326A patent/NZ571326A/en not_active IP Right Cessation
- 2007-03-20 DO DO2007000053A patent/DOP2007000053A/es unknown
- 2007-03-20 PA PA20078719401A patent/PA8719401A1/es unknown
- 2007-03-20 MX MX2008012006A patent/MX2008012006A/es active IP Right Grant
- 2007-03-20 RU RU2008141239/04A patent/RU2008141239A/ru not_active Application Discontinuation
- 2007-03-20 CN CN2007800178021A patent/CN101448840B/zh not_active Expired - Fee Related
- 2007-03-20 US US12/225,285 patent/US8501755B2/en not_active Expired - Fee Related
- 2007-03-20 JP JP2009501517A patent/JP5282026B2/ja not_active Expired - Fee Related
-
2008
- 2008-09-11 IL IL194028A patent/IL194028A0/en unknown
- 2008-09-18 ZA ZA200808017A patent/ZA200808017B/xx unknown
- 2008-09-18 SV SV2008003032A patent/SV2008003032A/es not_active Application Discontinuation
- 2008-09-18 GT GT200800187A patent/GT200800187A/es unknown
- 2008-09-19 EC EC2008008749A patent/ECSP088749A/es unknown
- 2008-09-19 CR CR10304A patent/CR10304A/es not_active Application Discontinuation
- 2008-09-22 TN TNP2008000370A patent/TNSN08370A1/en unknown
- 2008-10-20 MA MA31320A patent/MA30351B1/fr unknown
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