ATE496050T1 - Neue chinuklidinderivative und deren pharmazeutische verwendung - Google Patents

Neue chinuklidinderivative und deren pharmazeutische verwendung

Info

Publication number
ATE496050T1
ATE496050T1 AT04741916T AT04741916T ATE496050T1 AT E496050 T1 ATE496050 T1 AT E496050T1 AT 04741916 T AT04741916 T AT 04741916T AT 04741916 T AT04741916 T AT 04741916T AT E496050 T1 ATE496050 T1 AT E496050T1
Authority
AT
Austria
Prior art keywords
diseases
disorders
derivatives
quinuclide
new
Prior art date
Application number
AT04741916T
Other languages
English (en)
Inventor
Dan Peters
Gunnar M Olsen
Elsebet Ostergaard Nielsen
Philip K Ahring
Tino Dyhring Jorgensen
Michael Schrimpf
Kevin Sippy
Original Assignee
Neurosearch As
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/DK2003/000538 external-priority patent/WO2004016608A1/en
Application filed by Neurosearch As, Abbott Lab filed Critical Neurosearch As
Application granted granted Critical
Publication of ATE496050T1 publication Critical patent/ATE496050T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT04741916T 2003-08-13 2004-06-29 Neue chinuklidinderivative und deren pharmazeutische verwendung ATE496050T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/DK2003/000538 WO2004016608A1 (en) 2002-08-14 2003-08-13 Novel quinuclidine derivatives and their use
PCT/EP2004/051283 WO2005016923A1 (en) 2003-08-13 2004-06-29 Novel quinuclidine derivatives and their pharmaceutical use

Publications (1)

Publication Number Publication Date
ATE496050T1 true ATE496050T1 (de) 2011-02-15

Family

ID=34178319

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04741916T ATE496050T1 (de) 2003-08-13 2004-06-29 Neue chinuklidinderivative und deren pharmazeutische verwendung

Country Status (5)

Country Link
US (1) US7750022B2 (de)
EP (1) EP1656375B1 (de)
AT (1) ATE496050T1 (de)
DE (1) DE602004031124D1 (de)
WO (1) WO2005016923A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3623371A1 (de) 2014-12-16 2020-03-18 Axovant Sciences GmbH Geminale substituierte chinuklidinamidverbindungen als agonisten von alpha-7-nikotinischen acetylcholinrezeptoren
CN107847494A (zh) 2015-06-10 2018-03-27 阿考温特科学股份有限公司 作为α7‑烟碱乙酰胆碱受体激动剂的氨基苯并异噁唑化合物
JP2018523707A (ja) 2015-08-12 2018-08-23 アクソバント サイエンシズ ゲーエムベーハー α７−ニコチン性アセチルコリン受容体のアゴニストとしてのジェミナル置換アミノベンゾイソオキサゾール化合物

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU84791A (sh) 1990-05-19 1994-06-10 Boehringer Ingelheim Kg. Biciklicni 1-aza-cikloalkalni
KR930702312A (ko) 1990-08-31 1993-09-08 아만 히데아키 피리미딘 유도체 및 의약
ZA92278B (en) 1991-02-01 1992-10-28 Akzo Nv 3-quinuclidine derivatives
GB9201749D0 (en) 1992-01-28 1992-03-11 Smithkline Beecham Plc Medicaments
US5948793A (en) 1992-10-09 1999-09-07 Abbott Laboratories 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling neurotransmitter release
US5998404A (en) 1994-10-24 1999-12-07 Eli Lilly And Company Heterocyclic compounds and their use
US5672709A (en) 1994-10-24 1997-09-30 Eli Lilly And Company Heterocyclic compounds and their preparation and use
JPH08134067A (ja) 1994-11-11 1996-05-28 Yamanouchi Pharmaceut Co Ltd キヌクリジン誘導体
US5512574A (en) 1994-12-21 1996-04-30 American Home Products Corporation Quinuclidine and azabicyclo 2.2.1! heptane pyrazinyl ethers as muscarinic agonists
US5852037A (en) 1995-11-13 1998-12-22 Eli Lilly And Company Method for treating anxiety
CA2237311A1 (en) 1995-11-13 1997-05-22 Walter William Offen Method for treating anxiety
US5763457A (en) 1995-11-13 1998-06-09 Eli Lilly And Company Method for treating anxiety
AU1128297A (en) 1995-12-06 1997-06-27 Eli Lilly And Company Composition for treating pain
FR2754261B1 (fr) 1996-10-08 1998-10-30 Synthelabo Derives de quinuclidine, leur preparation et leur application en therapeutique
WO1998027983A1 (en) 1996-12-20 1998-07-02 Novo Nordisk A/S A method of treating hypercholesterolemia and related disorders
FR2772378B1 (fr) 1997-12-12 2000-02-04 Synthelabo Derives d'imidazole, leur preparation et leur application en therapeutique
US6953855B2 (en) 1998-12-11 2005-10-11 Targacept, Inc. 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof
DE10045112A1 (de) 2000-09-11 2002-03-21 Merck Patent Gmbh Verwendung von Indolderivaten zur Behandlung von Erkrankungen des zentralen Nervensystems
ATE385497T1 (de) 2000-12-01 2008-02-15 Neurosearch As 3-substituierte quinuclidin-derivate und deren verwendung als nikotinischen agonisten
JP2005511574A (ja) 2001-10-26 2005-04-28 ファルマシア アンド アップジョン カンパニー リミティド ライアビリティー カンパニー Ｎａｃｈｒアゴニストとしてのｎ−アザビシクロ−置換ヘテロ二環式カルボキサミド
CA2466375A1 (en) 2001-11-08 2003-05-15 Pharmacia & Upjohn Company Azabicyclic-substituted-heteroaryl compounds for the treatment of disease
MXPA04004373A (es) 2001-11-09 2004-08-11 Upjohn Co Compuestos heterociclicos condensados con fenilo azabiciclo para el tratamiento de enfermedades.
DE10156719A1 (de) 2001-11-19 2003-05-28 Bayer Ag Heteroarylcarbonsäureamide
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
EP1480977A2 (de) 2002-02-15 2004-12-01 PHARMACIA & UPJOHN COMPANY Substituierte arylverbindungen zur behandlung von krankheiten
CA2476681A1 (en) 2002-02-19 2003-08-28 Bruce N. Rogers Fused bicyclic-n-bridged-heteroaromatic carboxamides for the treatment of disease
CA2476624A1 (en) 2002-02-19 2003-08-28 Pharmacia & Upjohn Company Azabicyclic compounds for the treatment of disease
WO2003072578A1 (en) 2002-02-20 2003-09-04 Pharmacia & Upjohn Company Azabicyclic compounds with alfa7 nicotinic acetylcholine receptor activity
MXPA04012439A (es) 2002-06-10 2005-04-19 Bayer Healthcare Ag Amidas de acidos 2-heteroarilcarboxilicos.
WO2004016608A1 (en) 2002-08-14 2004-02-26 Neurosearch A/S Novel quinuclidine derivatives and their use
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
US20050171079A1 (en) * 2004-02-04 2005-08-04 Schrimpf Michael R. Amino-substituted tricyclic derivatives and methods of use

Also Published As

Publication number Publication date
EP1656375A1 (de) 2006-05-17
WO2005016923A1 (en) 2005-02-24
US20060217415A1 (en) 2006-09-28
EP1656375B1 (de) 2011-01-19
US7750022B2 (en) 2010-07-06
DE602004031124D1 (de) 2011-03-03

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Legal Events

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