ATE496050T1 - Neue chinuklidinderivative und deren pharmazeutische verwendung - Google Patents

Neue chinuklidinderivative und deren pharmazeutische verwendung

Info

Publication number
ATE496050T1
ATE496050T1 AT04741916T AT04741916T ATE496050T1 AT E496050 T1 ATE496050 T1 AT E496050T1 AT 04741916 T AT04741916 T AT 04741916T AT 04741916 T AT04741916 T AT 04741916T AT E496050 T1 ATE496050 T1 AT E496050T1
Authority
AT
Austria
Prior art keywords
diseases
disorders
derivatives
quinuclide
new
Prior art date
Application number
AT04741916T
Other languages
English (en)
Inventor
Dan Peters
Gunnar M Olsen
Elsebet Ostergaard Nielsen
Philip K Ahring
Tino Dyhring Jorgensen
Michael Schrimpf
Kevin Sippy
Original Assignee
Neurosearch As
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/DK2003/000538 external-priority patent/WO2004016608A1/en
Application filed by Neurosearch As, Abbott Lab filed Critical Neurosearch As
Application granted granted Critical
Publication of ATE496050T1 publication Critical patent/ATE496050T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT04741916T 2003-08-13 2004-06-29 Neue chinuklidinderivative und deren pharmazeutische verwendung ATE496050T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/DK2003/000538 WO2004016608A1 (en) 2002-08-14 2003-08-13 Novel quinuclidine derivatives and their use
PCT/EP2004/051283 WO2005016923A1 (en) 2003-08-13 2004-06-29 Novel quinuclidine derivatives and their pharmaceutical use

Publications (1)

Publication Number Publication Date
ATE496050T1 true ATE496050T1 (de) 2011-02-15

Family

ID=34178319

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04741916T ATE496050T1 (de) 2003-08-13 2004-06-29 Neue chinuklidinderivative und deren pharmazeutische verwendung

Country Status (5)

Country Link
US (1) US7750022B2 (de)
EP (1) EP1656375B1 (de)
AT (1) ATE496050T1 (de)
DE (1) DE602004031124D1 (de)
WO (1) WO2005016923A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3623371A1 (de) 2014-12-16 2020-03-18 Axovant Sciences GmbH Geminale substituierte chinuklidinamidverbindungen als agonisten von alpha-7-nikotinischen acetylcholinrezeptoren
CA2988968A1 (en) 2015-06-10 2016-12-15 Forum Pharmaceuticals, Inc. Aminobenzisoxazole compounds as agonists of a7-nicotinic acetylcholine receptors
WO2017027600A1 (en) 2015-08-12 2017-02-16 Forum Pharmaceuticals, Inc. GEMINAL SUBSTITUTED AMINOBENZISOXAZOLE COMPOUNDS AS AGONISTS OF α7-NICOTINIC ACETYLCHOLINE RECEPTORS

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU84791A (sh) 1990-05-19 1994-06-10 Boehringer Ingelheim Kg. Biciklicni 1-aza-cikloalkalni
EP0555478A4 (en) 1990-08-31 1993-11-18 Nippon Shinyaku Company, Limited Pyrimidine derivative and medicine
ZA92278B (en) * 1991-02-01 1992-10-28 Akzo Nv 3-quinuclidine derivatives
GB9201749D0 (en) * 1992-01-28 1992-03-11 Smithkline Beecham Plc Medicaments
US5948793A (en) * 1992-10-09 1999-09-07 Abbott Laboratories 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling neurotransmitter release
US5821370A (en) * 1994-10-24 1998-10-13 Eli Lilly And Company Heterocyclic compounds and their preparation and use
US5998404A (en) 1994-10-24 1999-12-07 Eli Lilly And Company Heterocyclic compounds and their use
JPH08134067A (ja) * 1994-11-11 1996-05-28 Yamanouchi Pharmaceut Co Ltd キヌクリジン誘導体
US5512574A (en) * 1994-12-21 1996-04-30 American Home Products Corporation Quinuclidine and azabicyclo 2.2.1! heptane pyrazinyl ethers as muscarinic agonists
US5852037A (en) * 1995-11-13 1998-12-22 Eli Lilly And Company Method for treating anxiety
US5763457A (en) * 1995-11-13 1998-06-09 Eli Lilly And Company Method for treating anxiety
CA2237311A1 (en) * 1995-11-13 1997-05-22 Walter William Offen Method for treating anxiety
WO1997020819A1 (en) 1995-12-06 1997-06-12 Eli Lilly And Company Composition for treating pain
FR2754261B1 (fr) 1996-10-08 1998-10-30 Synthelabo Derives de quinuclidine, leur preparation et leur application en therapeutique
AU7871498A (en) 1996-12-20 1998-07-17 Novo Nordisk A/S A method of treating hypercholesterolemia and related disorders
FR2772378B1 (fr) 1997-12-12 2000-02-04 Synthelabo Derives d'imidazole, leur preparation et leur application en therapeutique
US6953855B2 (en) 1998-12-11 2005-10-11 Targacept, Inc. 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof
DE10045112A1 (de) 2000-09-11 2002-03-21 Merck Patent Gmbh Verwendung von Indolderivaten zur Behandlung von Erkrankungen des zentralen Nervensystems
DE60132710T2 (de) 2000-12-01 2008-06-12 Neurosearch A/S 3-substituierte chinuclidine und ihre verwendung als nikotinische agonisten
CA2464194A1 (en) 2001-10-26 2003-05-08 Pharmacia & Upjohn Company N-azabicyclo-substituted hetero-bicyclic carboxamides as nachr agonists
MXPA04004464A (es) 2001-11-08 2004-08-11 Upjohn Co Compuestos de heteroarilo sustituido con azabiciclo para el tratamiento de enfermedades.
US6951868B2 (en) 2001-11-09 2005-10-04 Pfizer Inc. Azabicyclic-phenyl-fused-heterocyclic compounds for treatment of disease
DE10156719A1 (de) 2001-11-19 2003-05-28 Bayer Ag Heteroarylcarbonsäureamide
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
JP2005522456A (ja) 2002-02-15 2005-07-28 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー Ｃｎｓ関連障害治療のためのアザビシクロ置換ベンゾイルアミドおよびチオアミド
BR0307782A (pt) 2002-02-19 2005-01-04 Upjohn Co Compostos azabiciclo para o tratamento de doença
US6858613B2 (en) 2002-02-19 2005-02-22 Pfizer Inc. Fused bicyclic-N-bridged-heteroaromatic carboxamides for the treatment of disease
WO2003072578A1 (en) 2002-02-20 2003-09-04 Pharmacia & Upjohn Company Azabicyclic compounds with alfa7 nicotinic acetylcholine receptor activity
CN1675204A (zh) 2002-06-10 2005-09-28 拜耳医药保健股份公司 2－杂芳基甲酰胺
MXPA05001702A (es) * 2002-08-14 2005-04-19 Neurosearch As Derivados de quinuclidina novedosos y su uso.
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
US20050171079A1 (en) * 2004-02-04 2005-08-04 Schrimpf Michael R. Amino-substituted tricyclic derivatives and methods of use

Also Published As

Publication number Publication date
US20060217415A1 (en) 2006-09-28
DE602004031124D1 (de) 2011-03-03
EP1656375B1 (de) 2011-01-19
US7750022B2 (en) 2010-07-06
EP1656375A1 (de) 2006-05-17
WO2005016923A1 (en) 2005-02-24

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