ATE496298T1 - Methode um die sensitivität einer luminesenz assay zu erhöhen - Google Patents

Methode um die sensitivität einer luminesenz assay zu erhöhen

Info

Publication number
ATE496298T1
ATE496298T1 AT01942027T AT01942027T ATE496298T1 AT E496298 T1 ATE496298 T1 AT E496298T1 AT 01942027 T AT01942027 T AT 01942027T AT 01942027 T AT01942027 T AT 01942027T AT E496298 T1 ATE496298 T1 AT E496298T1
Authority
AT
Austria
Prior art keywords
fold
reduces
sensitivity
luminescence
assay
Prior art date
Application number
AT01942027T
Other languages
English (en)
Inventor
Erika Hawkins
John Centanni
Jacqueline Sankbeil
Keith Wood
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24364121&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE496298(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Promega Corp filed Critical Promega Corp
Application granted granted Critical
Publication of ATE496298T1 publication Critical patent/ATE496298T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/90241—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT01942027T 2000-06-09 2001-06-07 Methode um die sensitivität einer luminesenz assay zu erhöhen ATE496298T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/590,884 US7118878B1 (en) 2000-06-09 2000-06-09 Method for increasing luminescence assay sensitivity
PCT/US2001/018363 WO2001096862A2 (en) 2000-06-09 2001-06-07 Method for increasing luminescence assay sensitivity

Publications (1)

Publication Number Publication Date
ATE496298T1 true ATE496298T1 (de) 2011-02-15

Family

ID=24364121

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01942027T ATE496298T1 (de) 2000-06-09 2001-06-07 Methode um die sensitivität einer luminesenz assay zu erhöhen

Country Status (8)

Country Link
US (3) US7118878B1 (de)
EP (1) EP1297337B1 (de)
JP (2) JP4685325B2 (de)
AT (1) ATE496298T1 (de)
AU (2) AU2001275325B2 (de)
CA (1) CA2411179A1 (de)
DE (1) DE60143888D1 (de)
WO (1) WO2001096862A2 (de)

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US7118878B1 (en) * 2000-06-09 2006-10-10 Promega Corporation Method for increasing luminescence assay sensitivity
AU2003267245C1 (en) 2002-09-20 2008-05-29 Promega Corporation Luminescence-based methods and probes for measuring cytochrome P450 activity
AU2003300008B2 (en) 2002-12-23 2007-04-05 Promega Corporation Improved luciferase-based assays
AU2004210982B2 (en) * 2003-02-12 2008-12-18 Promega Corporation Methods and kits for dual enzymatic assays whereby light is quenched from luminescent reactions
EP2272973B1 (de) 2005-05-31 2015-05-27 Promega Corporation Luminogene und fluorogene Verbindungen und Verfahren für den Nachweis von Molekülen oder Leiden
WO2008045121A1 (en) * 2006-10-13 2008-04-17 Charm Sciences, Inc. Method and apparatus for reducing luminescent test result interferences
US20080248511A1 (en) * 2007-03-26 2008-10-09 Promega Corporation Methods to quench light from optical reactions
US8431698B2 (en) * 2007-08-29 2013-04-30 Biolume Inc. Bioluminescent endoscopy methods and compounds
US8512968B2 (en) 2007-10-29 2013-08-20 Perkinelmer Health Sciences B.V. Methods, reagents and kits for luciferase assay
US8288559B2 (en) * 2008-08-18 2012-10-16 Promega Corporation Luminogenic compounds and methods to detect cytochrome P450 3A enzymes
DK2456864T3 (en) 2009-05-01 2015-12-21 Promega Corp SYNTHETIC OPLOPHORUS luciferases WITH IMPROVED LIGHT MISSION
PT2635583E (pt) 2010-11-02 2015-09-11 Promega Corp Derivados da coelenterazina e métodos de utilização da mesma
US8669103B2 (en) 2010-11-02 2014-03-11 Promega Corporation Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use
JP6117703B2 (ja) * 2010-12-14 2017-04-19 ステイックティング カソリエケ ユニベルシテイト 化学発光に基づく止血アッセイ
US20120204906A1 (en) * 2011-02-15 2012-08-16 3M Innovative Properties Company Method of controlling a decontamination process
EP2780707B1 (de) 2012-05-02 2016-02-24 Charles River Laboratories, Inc. Nachweisverfahren für lebenfähige zellen in einer zellprobe
CN104685346B (zh) 2012-05-02 2018-05-29 查尔斯河实验室公司 细胞捕获系统及其使用
US8993259B2 (en) 2012-05-02 2015-03-31 Charles River Laboratories, Inc. Method of viability staining with membrane permeable fluorescent dye and membrane impermeable fluorescence quencher
US9927430B2 (en) 2014-01-29 2018-03-27 Promega Corporation Pro-substrates for live cell applications
WO2015116867A1 (en) 2014-01-29 2015-08-06 Promega Corporation Quinone-masked probes as labeling reagents for cell uptake measurements
WO2017155036A1 (ja) 2016-03-11 2017-09-14 国立研究開発法人産業技術総合研究所 発光酵素タンパク質
WO2019028272A1 (en) 2017-08-04 2019-02-07 Promega Corporation COMPOSITIONS AND METHODS FOR STABILIZING LUCIFERIN BENZOTHIAZOLE ANALOGS
KR20220007058A (ko) * 2019-04-10 2022-01-18 프로메가 코포레이션 생물발광을 이용하는 분석물 검출을 위한 조성물 및 방법
WO2024262411A1 (ja) * 2023-06-22 2024-12-26 国立研究開発法人産業技術総合研究所 血清アルブミンの検出剤
CN119551880B (zh) * 2025-02-06 2025-04-08 山东黄金矿业科技有限公司选冶实验室分公司 一种含氰废水中硫氰根的脱除方法

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SE428379B (sv) 1978-05-31 1983-06-27 Lkb Produkter Ab Bioluminiscens bestemning av atp och reagens herfor
DE2828658C3 (de) 1978-06-29 1981-10-22 Lkb-Produkter Ab, Stockholm Verfahren zur photometrischen Bestimmung der Untereinheit B der Creatinkinase und Reagens hierfür
DE2901919C2 (de) 1979-01-18 1987-04-02 Laboratorium Prof. Dr. Rudolf Berthold, 7547 Wildbad Verfahren zur photometrischen Reihenmessung an Reaktionsvorgängen in flüssigen Proben und Vorrichtung zur Durchführung des Verfahrens
SE432112B (sv) * 1979-07-12 1984-03-19 Lkb Produkter Ab Forfarande for bestemning av kreatinkinas i prover innehallande atp
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US6221612B1 (en) * 1997-08-01 2001-04-24 Aurora Biosciences Corporation Photon reducing agents for use in fluorescence assays
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DE69915468T2 (de) 1999-09-01 2005-01-20 Invitrogen Corp., Carlsbad Photon Dämpfer für Fluoreszenzassays
US7118878B1 (en) 2000-06-09 2006-10-10 Promega Corporation Method for increasing luminescence assay sensitivity
US6867005B2 (en) * 2001-10-24 2005-03-15 Beckman Coulter, Inc. Method and apparatus for increasing the dynamic range and accuracy of binding assays
AU2004210982B2 (en) 2003-02-12 2008-12-18 Promega Corporation Methods and kits for dual enzymatic assays whereby light is quenched from luminescent reactions

Also Published As

Publication number Publication date
JP4685325B2 (ja) 2011-05-18
JP2004503777A (ja) 2004-02-05
WO2001096862A3 (en) 2002-07-18
EP1297337B1 (de) 2011-01-19
US7118878B1 (en) 2006-10-10
DE60143888D1 (de) 2011-03-03
CA2411179A1 (en) 2001-12-20
US7108996B2 (en) 2006-09-19
EP1297337A2 (de) 2003-04-02
WO2001096862A2 (en) 2001-12-20
AU7532501A (en) 2001-12-24
US20060051827A1 (en) 2006-03-09
JP2011064690A (ja) 2011-03-31
US7078181B2 (en) 2006-07-18
AU2001275325B2 (en) 2006-10-05
US20040096924A1 (en) 2004-05-20

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