ATE496298T1 - Methode um die sensitivität einer luminesenz assay zu erhöhen - Google Patents

Methode um die sensitivität einer luminesenz assay zu erhöhen

Info

Publication number
ATE496298T1
ATE496298T1 AT01942027T AT01942027T ATE496298T1 AT E496298 T1 ATE496298 T1 AT E496298T1 AT 01942027 T AT01942027 T AT 01942027T AT 01942027 T AT01942027 T AT 01942027T AT E496298 T1 ATE496298 T1 AT E496298T1
Authority
AT
Austria
Prior art keywords
fold
reduces
sensitivity
luminescence
assay
Prior art date
Application number
AT01942027T
Other languages
English (en)
Inventor
Erika Hawkins
John Centanni
Jacqueline Sankbeil
Keith Wood
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24364121&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE496298(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Promega Corp filed Critical Promega Corp
Application granted granted Critical
Publication of ATE496298T1 publication Critical patent/ATE496298T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/90241—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT01942027T 2000-06-09 2001-06-07 Methode um die sensitivität einer luminesenz assay zu erhöhen ATE496298T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/590,884 US7118878B1 (en) 2000-06-09 2000-06-09 Method for increasing luminescence assay sensitivity
PCT/US2001/018363 WO2001096862A2 (en) 2000-06-09 2001-06-07 Method for increasing luminescence assay sensitivity

Publications (1)

Publication Number Publication Date
ATE496298T1 true ATE496298T1 (de) 2011-02-15

Family

ID=24364121

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01942027T ATE496298T1 (de) 2000-06-09 2001-06-07 Methode um die sensitivität einer luminesenz assay zu erhöhen

Country Status (8)

Country Link
US (3) US7118878B1 (de)
EP (1) EP1297337B1 (de)
JP (2) JP4685325B2 (de)
AT (1) ATE496298T1 (de)
AU (2) AU2001275325B2 (de)
CA (1) CA2411179A1 (de)
DE (1) DE60143888D1 (de)
WO (1) WO2001096862A2 (de)

Families Citing this family (25)

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US7118878B1 (en) 2000-06-09 2006-10-10 Promega Corporation Method for increasing luminescence assay sensitivity
CA2497560A1 (en) 2002-09-20 2004-04-01 Promega Corporation Luminescence-based methods and probes for measuring cytochrome p450 activity
AU2003300008B2 (en) 2002-12-23 2007-04-05 Promega Corporation Improved luciferase-based assays
EP1592805A1 (de) * 2003-02-12 2005-11-09 Promega Corporation Methoden und kits für duale enzymtests, wobei licht aus lumineszenten reaktionen gelöscht wird
EP1885875B1 (de) 2005-05-31 2019-05-22 Promega Corporation Luminogene und fluorogene verbindungen und verfahren für den nachweis von molekülen oder leiden
WO2008045121A1 (en) * 2006-10-13 2008-04-17 Charm Sciences, Inc. Method and apparatus for reducing luminescent test result interferences
WO2008118445A1 (en) * 2007-03-26 2008-10-02 Promega Corporation Methods to quench light from optical reactions
WO2009032218A1 (en) * 2007-08-29 2009-03-12 Biolume Inc. Bioluminescent endoscopy methods and compounds
ES2390395T3 (es) 2007-10-29 2012-11-12 Perkinelmer Health Sciences B.V. Métodos, reactivos y kits para el ensayo de luciferasa
JP5597200B2 (ja) * 2008-08-18 2014-10-01 プロメガ コーポレイション ルミネッセンスを生じる化合物およびチトクロムｐ４５０３ａ酵素を検出するための方法
WO2010127368A1 (en) 2009-05-01 2010-11-04 Promega Corporation Synthetic oplophorus luciferases with enhanced light output
SG10202103336SA (en) 2010-11-02 2021-04-29 Promega Corp Novel coelenterazine substrates and methods of use
AU2011323455B2 (en) 2010-11-02 2017-07-27 Promega Corporation Coelenterazine derivatives and methods of using same
US9856510B2 (en) * 2010-12-14 2018-01-02 Stichting Katholieke Universiteit Chemiluminescence-based haemostasis assay
US20120204906A1 (en) * 2011-02-15 2012-08-16 3M Innovative Properties Company Method of controlling a decontamination process
CN104662425B (zh) 2012-05-02 2017-10-10 查尔斯河实验室公司 活性染色方法
CN104685346B (zh) 2012-05-02 2018-05-29 查尔斯河实验室公司 细胞捕获系统及其使用
JP6482459B2 (ja) 2012-05-02 2019-03-13 チャールズ リバー ラボラトリーズ， インコーポレイテッド 細胞サンプル中の生存細胞を検出する方法
EP3099683B1 (de) 2014-01-29 2020-08-05 Promega Corporation Chinonmaskierte sonden als markierungsreagenzien für zellaufnahmemessungen
JP6588917B2 (ja) 2014-01-29 2019-10-09 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ 生細胞への適用のためのプロ基質
WO2017155036A1 (ja) 2016-03-11 2017-09-14 国立研究開発法人産業技術総合研究所 発光酵素タンパク質
US11136615B2 (en) 2017-08-04 2021-10-05 Promega Corporation Compositions and methods for stabilizing benzothiazole luciferin analogs
EP3953374A4 (de) * 2019-04-10 2023-06-07 Promega Corporation Zusammensetzungen und verfahren zur detektion von analyten mittels biolumineszenz
WO2024262411A1 (ja) * 2023-06-22 2024-12-26 国立研究開発法人産業技術総合研究所 血清アルブミンの検出剤
CN119551880B (zh) * 2025-02-06 2025-04-08 山东黄金矿业科技有限公司选冶实验室分公司 一种含氰废水中硫氰根的脱除方法

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SE428379B (sv) 1978-05-31 1983-06-27 Lkb Produkter Ab Bioluminiscens bestemning av atp och reagens herfor
DE2828658C3 (de) 1978-06-29 1981-10-22 Lkb-Produkter Ab, Stockholm Verfahren zur photometrischen Bestimmung der Untereinheit B der Creatinkinase und Reagens hierfür
DE2901919C2 (de) 1979-01-18 1987-04-02 Laboratorium Prof. Dr. Rudolf Berthold, 7547 Wildbad Verfahren zur photometrischen Reihenmessung an Reaktionsvorgängen in flüssigen Proben und Vorrichtung zur Durchführung des Verfahrens
SE432112B (sv) * 1979-07-12 1984-03-19 Lkb Produkter Ab Forfarande for bestemning av kreatinkinas i prover innehallande atp
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US6221612B1 (en) * 1997-08-01 2001-04-24 Aurora Biosciences Corporation Photon reducing agents for use in fluorescence assays
US6200762B1 (en) 1997-08-01 2001-03-13 Aurora Biosciences Corporation Photon reducing agents and compositions for fluorescence assays
EP1081495B1 (de) 1999-09-01 2004-03-10 Invitrogen Corporation Photon Dämpfer für Fluoreszenzassays
US7118878B1 (en) 2000-06-09 2006-10-10 Promega Corporation Method for increasing luminescence assay sensitivity
US6867005B2 (en) * 2001-10-24 2005-03-15 Beckman Coulter, Inc. Method and apparatus for increasing the dynamic range and accuracy of binding assays
EP1592805A1 (de) 2003-02-12 2005-11-09 Promega Corporation Methoden und kits für duale enzymtests, wobei licht aus lumineszenten reaktionen gelöscht wird

Also Published As

Publication number Publication date
US7118878B1 (en) 2006-10-10
WO2001096862A3 (en) 2002-07-18
US20040096924A1 (en) 2004-05-20
EP1297337B1 (de) 2011-01-19
EP1297337A2 (de) 2003-04-02
DE60143888D1 (de) 2011-03-03
JP4685325B2 (ja) 2011-05-18
AU7532501A (en) 2001-12-24
CA2411179A1 (en) 2001-12-20
AU2001275325B2 (en) 2006-10-05
JP2004503777A (ja) 2004-02-05
WO2001096862A2 (en) 2001-12-20
US7108996B2 (en) 2006-09-19
US7078181B2 (en) 2006-07-18
JP2011064690A (ja) 2011-03-31
US20060051827A1 (en) 2006-03-09

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