ATE497013T1 - Verfahren zur herstellung von glutaminsäurederivaten - Google Patents

Verfahren zur herstellung von glutaminsäurederivaten

Info

Publication number
ATE497013T1
ATE497013T1 AT02783795T AT02783795T ATE497013T1 AT E497013 T1 ATE497013 T1 AT E497013T1 AT 02783795 T AT02783795 T AT 02783795T AT 02783795 T AT02783795 T AT 02783795T AT E497013 T1 ATE497013 T1 AT E497013T1
Authority
AT
Austria
Prior art keywords
acid derivatives
glutamine acid
producing glutamine
producing
general formula
Prior art date
Application number
AT02783795T
Other languages
English (en)
Inventor
Masakazu Sugiyama
Kunihiko Watanabe
Nao Funakoshi
Yusuke Amino
Shigeru Kawahara
Tadashi Takemoto
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26625318&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE497013(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of ATE497013T1 publication Critical patent/ATE497013T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
AT02783795T 2001-12-27 2002-12-09 Verfahren zur herstellung von glutaminsäurederivaten ATE497013T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001396471 2001-12-27
JP2002095760 2002-03-29
PCT/JP2002/012852 WO2003056026A1 (en) 2001-12-27 2002-12-09 Process for production of glutamic acid derivatives

Publications (1)

Publication Number Publication Date
ATE497013T1 true ATE497013T1 (de) 2011-02-15

Family

ID=26625318

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02783795T ATE497013T1 (de) 2001-12-27 2002-12-09 Verfahren zur herstellung von glutaminsäurederivaten

Country Status (10)

Country Link
EP (3) EP1445323B1 (de)
JP (1) JP4301003B2 (de)
KR (2) KR100673283B1 (de)
CN (2) CN101671707A (de)
AT (1) ATE497013T1 (de)
AU (1) AU2002349493A1 (de)
CA (1) CA2469012C (de)
DE (1) DE60239072D1 (de)
RU (2) RU2280078C2 (de)
WO (1) WO2003056026A1 (de)

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US7297800B2 (en) 2001-12-27 2007-11-20 Ajinomoto Co., Inc. Process of producing glutamate derivatives
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US8372989B2 (en) 2002-04-23 2013-02-12 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
CA2484871C (en) * 2002-08-26 2010-11-30 Ajinomoto Co., Inc. Novel aldolase and production process of substituted .alpha.-keto acids
AU2003289264A1 (en) 2002-12-09 2004-06-30 Ajinomoto Co., Inc. Mutant d-aminotransferase and process for producing optically active glutamic acid derivative using the same
CN102210852B (zh) 2003-05-15 2016-10-19 安皮奥制药股份有限公司 T-细胞介导的疾病的治疗
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US20050106305A1 (en) * 2003-08-25 2005-05-19 Cargill, Inc. Beverage compositions comprising monatin and methods of making same
US8206955B2 (en) * 2003-10-21 2012-06-26 Cargill, Incorporated Production of monatin and monatin precursors
JP4500977B2 (ja) * 2003-11-05 2010-07-14 味の素株式会社 新規アミノ酸誘導体及び甘味剤
JP5113978B2 (ja) * 2003-11-21 2013-01-09 味の素株式会社 グルタミン酸誘導体の有機アミン塩及びその利用
CA2506247C (en) * 2004-06-07 2012-02-21 Ajinomoto Co., Inc. Novel aldolase, and method for producing optically active ihog and monatin
JP4797452B2 (ja) * 2004-06-07 2011-10-19 味の素株式会社 新規アルドラーゼ並びに光学活性ｉｈｏｇ及びモナティンの製造方法
JPWO2006038520A1 (ja) 2004-10-05 2008-05-15 味の素株式会社 ヒドロキシイミノ酸からのアミノ酸誘導体製造方法
CN101035442B (zh) * 2004-10-15 2012-04-11 味之素株式会社 甜味剂组合物
EP1883817A4 (de) * 2005-04-20 2009-09-23 Cargill Inc Produkte und verfahren zur in-vivo-sekretion von monatin
US8158389B2 (en) 2005-04-20 2012-04-17 Cargill, Incorporated Products and methods for in vivo secretion of monatin
US7582455B2 (en) 2005-04-26 2009-09-01 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
US8076108B2 (en) 2005-04-26 2011-12-13 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
AU2006341528A1 (en) * 2005-04-26 2007-12-06 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
ES2416104T3 (es) 2006-03-07 2013-07-30 Cargill, Incorporated Aldolasas, ácidos nucleicos que las codifican y métodos para producir y usar las mismas
JP2009538145A (ja) 2006-05-24 2009-11-05 カーギル・インコーポレイテッド 平衡反応の収量を増加させるための方法およびシステム
CN101239941B (zh) * 2007-02-08 2012-02-29 味之素株式会社 光学活性化合物的制造方法
WO2009028338A1 (ja) 2007-08-24 2009-03-05 Ajinomoto Co., Inc. 新規オキシダーゼ遺伝子、および該遺伝子を利用する３－インドールピルビン酸の製造方法
US8003361B2 (en) 2007-10-01 2011-08-23 Cargill Incorporated Production of monatin enantiomers
US8076107B2 (en) * 2007-10-01 2011-12-13 Cargill, Incorporated Production of monatin stereoisomers
US8367847B2 (en) 2007-10-01 2013-02-05 Cargill, Incorporated Production of monatin enantiomers
EP2107053A1 (de) 2008-03-11 2009-10-07 Ajinomoto Co., Inc. Hydratkristalle von (2R,4R)-Monatin Mononatrium-Salz
JP5856843B2 (ja) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ，インコーポレイテッド ジケトピペラジンを用いた医薬組成物
EP2613786A4 (de) 2010-09-07 2013-10-23 Dmi Acquisition Corp Behandlung von erkrankungen
KR20120068872A (ko) 2010-10-14 2012-06-27 아지노모토 가부시키가이샤 모나틴의 제조 방법
US8771997B2 (en) 2011-04-20 2014-07-08 Ajinomoto Co., Inc. Method for producing monatin using an L-amino acid aminotransferase
PH12014500685B1 (en) 2011-10-10 2018-10-03 Ampio Pharmaceuticals Inc Treatment of degenerative joint disease
JP2014530063A (ja) 2011-10-10 2014-11-17 アンピオ ファーマシューティカルズ，インコーポレイテッド 免疫寛容が高められた埋込み型医療用デバイス、ならびに製造方法および埋込み方法
HK1198812A1 (en) 2011-10-28 2015-06-12 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
WO2013073679A1 (ja) * 2011-11-17 2013-05-23 味の素株式会社 （２ｒ，４ｒ）モナティン多価金属塩結晶の製造方法
CN102586343B (zh) * 2012-02-27 2013-07-17 重庆邮电大学 一种从l-丙氨酸制备丙酮酸的生物催化方法
CA2906864A1 (en) 2013-03-15 2014-09-18 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
EP4066836A1 (de) 2014-08-18 2022-10-05 Ampio Pharmaceuticals, Inc. Behandlung von gelenkerkrankungen
EP3310375A4 (de) 2015-06-22 2019-02-20 Ampio Pharmaceuticals, Inc. Verwendung von niedermolekularen fraktionen von humanem serumalbumin bei der behandlung von erkrankungen
CN117050900A (zh) * 2023-06-29 2023-11-14 路德环境科技股份有限公司 一株产γ-聚谷氨酸的球形赖氨酸芽孢杆菌及其应用

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JP3052413B2 (ja) * 1990-05-25 2000-06-12 エヌオーケー株式会社 インド−ルピルビン酸の製造方法
DD297190A5 (de) 1990-08-06 1992-01-02 Ernst-Moritz-Arndt-Universitaet Greifswald,De Verfahren zur enzymatischen herstellung von indolpyruvat
CA2153561A1 (en) * 1994-07-11 1996-01-12 Ryoichi Katsumata Process for producing an optically active .gamma.-hydroxy-l-glutamic acid
US6358714B1 (en) 1995-04-03 2002-03-19 The Nutrasweet Company Materials and methods for the production of D-phenylalanine
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US5994559A (en) 1998-08-06 1999-11-30 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Synthesis of monatin-A high intensity natural sweetener
CN100465156C (zh) * 2001-12-27 2009-03-04 味之素株式会社 谷氨酸化合物及其制备中间体的制造方法与为此所用的新型中间体
PL208481B1 (pl) * 2002-04-23 2011-05-31 Cargill Sposób wytwarzania monatyny
CA2484871C (en) * 2002-08-26 2010-11-30 Ajinomoto Co., Inc. Novel aldolase and production process of substituted .alpha.-keto acids
AU2003289264A1 (en) * 2002-12-09 2004-06-30 Ajinomoto Co., Inc. Mutant d-aminotransferase and process for producing optically active glutamic acid derivative using the same

Also Published As

Publication number Publication date
CA2469012A1 (en) 2003-07-10
RU2280078C2 (ru) 2006-07-20
EP1445323A4 (de) 2010-01-27
EP1445323A1 (de) 2004-08-11
EP2460884A2 (de) 2012-06-06
EP2460884A3 (de) 2013-03-27
RU2004122914A (ru) 2005-03-27
CN100549182C (zh) 2009-10-14
CN1610749A (zh) 2005-04-27
KR20040066830A (ko) 2004-07-27
JPWO2003056026A1 (ja) 2005-05-12
AU2002349493A1 (en) 2003-07-15
DE60239072D1 (de) 2011-03-10
JP4301003B2 (ja) 2009-07-22
KR20060060750A (ko) 2006-06-05
EP2330211A3 (de) 2013-03-27
CN101671707A (zh) 2010-03-17
WO2003056026A1 (en) 2003-07-10
CA2469012C (en) 2013-06-04
RU2006108992A (ru) 2007-10-10
EP2330211A2 (de) 2011-06-08
KR100673283B1 (ko) 2007-01-24
EP1445323B1 (de) 2011-01-26
KR100775778B1 (ko) 2007-11-12
RU2325442C2 (ru) 2008-05-27

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