ATE552242T1 - ßVERFAHREN ZUR HERSTELLUNG VON GLUTAMINSÄUREVERBINDUNGEN UND ZWISCHENPRODUKTEN DAVON, UND IN DEN VERFAHREN VERWENDETE NEUE ZWISCHENPRODUKTEß - Google Patents

ßVERFAHREN ZUR HERSTELLUNG VON GLUTAMINSÄUREVERBINDUNGEN UND ZWISCHENPRODUKTEN DAVON, UND IN DEN VERFAHREN VERWENDETE NEUE ZWISCHENPRODUKTEß

Info

Publication number
ATE552242T1
ATE552242T1 AT02783682T AT02783682T ATE552242T1 AT E552242 T1 ATE552242 T1 AT E552242T1 AT 02783682 T AT02783682 T AT 02783682T AT 02783682 T AT02783682 T AT 02783682T AT E552242 T1 ATE552242 T1 AT E552242T1
Authority
AT
Austria
Prior art keywords
intermediate products
preparation
acid compounds
acid compound
intermediates
Prior art date
Application number
AT02783682T
Other languages
English (en)
Inventor
Shigeru Kawahara
Yusuke Amino
Kenichi Mori
Nao Funakoshi
Tadashi Takemoto
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27482750&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE552242(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of ATE552242T1 publication Critical patent/ATE552242T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/24—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C07C51/38—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT02783682T 2001-12-27 2002-11-29 ßVERFAHREN ZUR HERSTELLUNG VON GLUTAMINSÄUREVERBINDUNGEN UND ZWISCHENPRODUKTEN DAVON, UND IN DEN VERFAHREN VERWENDETE NEUE ZWISCHENPRODUKTEß ATE552242T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2001396300 2001-12-27
JP2002149069 2002-05-23
JP2002149078 2002-05-23
JP2002182032 2002-06-21
PCT/JP2002/012473 WO2003059865A1 (en) 2001-12-27 2002-11-29 Processes for the preparation of glutamic acid compounds and intermediates thereof and novel intermediates used in the processes

Publications (1)

Publication Number Publication Date
ATE552242T1 true ATE552242T1 (de) 2012-04-15

Family

ID=27482750

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02783682T ATE552242T1 (de) 2001-12-27 2002-11-29 ßVERFAHREN ZUR HERSTELLUNG VON GLUTAMINSÄUREVERBINDUNGEN UND ZWISCHENPRODUKTEN DAVON, UND IN DEN VERFAHREN VERWENDETE NEUE ZWISCHENPRODUKTEß

Country Status (10)

Country Link
US (6) US7064219B2 (de)
EP (1) EP1466890B1 (de)
JP (2) JP4196832B2 (de)
KR (1) KR100906947B1 (de)
CN (2) CN100465156C (de)
AT (1) ATE552242T1 (de)
AU (1) AU2002349606A1 (de)
CA (1) CA2471847C (de)
ES (1) ES2383518T3 (de)
WO (1) WO2003059865A1 (de)

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US7297800B2 (en) * 2001-12-27 2007-11-20 Ajinomoto Co., Inc. Process of producing glutamate derivatives
DE60239072D1 (de) * 2001-12-27 2011-03-10 Ajinomoto Kk Verfahren zur herstellung von glutaminsäurederivaten
CN100465156C (zh) * 2001-12-27 2009-03-04 味之素株式会社 谷氨酸化合物及其制备中间体的制造方法与为此所用的新型中间体
US8372989B2 (en) 2002-04-23 2013-02-12 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
US7572607B2 (en) 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
CA2484871C (en) 2002-08-26 2010-11-30 Ajinomoto Co., Inc. Novel aldolase and production process of substituted .alpha.-keto acids
AU2003289264A1 (en) * 2002-12-09 2004-06-30 Ajinomoto Co., Inc. Mutant d-aminotransferase and process for producing optically active glutamic acid derivative using the same
KR101160473B1 (ko) * 2003-01-09 2012-06-28 아지노모토 가부시키가이샤 글루탐산 유도체 및 피로글루탐산 유도체의 제조 방법 및신규 제조 중간체
EP1648248A2 (de) * 2003-08-01 2006-04-26 Cargill, Incorporated Monatin-süssstoffzusammensetzungen für den tisch und verfahren zur herstellung davon
US20050106305A1 (en) * 2003-08-25 2005-05-19 Cargill, Inc. Beverage compositions comprising monatin and methods of making same
US8206955B2 (en) 2003-10-21 2012-06-26 Cargill, Incorporated Production of monatin and monatin precursors
JP5113978B2 (ja) * 2003-11-21 2013-01-09 味の素株式会社 グルタミン酸誘導体の有機アミン塩及びその利用
JP5319885B2 (ja) * 2004-02-27 2013-10-16 味の素株式会社 モナティンの製造方法
US7935377B2 (en) * 2004-06-04 2011-05-03 Ajinomoto Co., Inc. Crystals of free (2R, 4R)-monatin and use thereof
CA2506247C (en) 2004-06-07 2012-02-21 Ajinomoto Co., Inc. Novel aldolase, and method for producing optically active ihog and monatin
KR101216575B1 (ko) * 2004-07-14 2012-12-31 아지노모토 가부시키가이샤 (2ｒ,4ｒ)-모나틴 칼륨 염 결정 및 이를 함유하는 감미료조성물
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CN101035442B (zh) * 2004-10-15 2012-04-11 味之素株式会社 甜味剂组合物
EP1883817A4 (de) 2005-04-20 2009-09-23 Cargill Inc Produkte und verfahren zur in-vivo-sekretion von monatin
US8158389B2 (en) 2005-04-20 2012-04-17 Cargill, Incorporated Products and methods for in vivo secretion of monatin
US7582455B2 (en) 2005-04-26 2009-09-01 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
US8076108B2 (en) 2005-04-26 2011-12-13 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
ES2416104T3 (es) 2006-03-07 2013-07-30 Cargill, Incorporated Aldolasas, ácidos nucleicos que las codifican y métodos para producir y usar las mismas
JP2009538145A (ja) 2006-05-24 2009-11-05 カーギル・インコーポレイテッド 平衡反応の収量を増加させるための方法およびシステム
US20090198072A1 (en) * 2006-05-24 2009-08-06 Cargill, Incorporated Methods and systems for increasing production of equilibrium reactions
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
CN101239941B (zh) * 2007-02-08 2012-02-29 味之素株式会社 光学活性化合物的制造方法
US8367847B2 (en) 2007-10-01 2013-02-05 Cargill, Incorporated Production of monatin enantiomers
US8076107B2 (en) 2007-10-01 2011-12-13 Cargill, Incorporated Production of monatin stereoisomers
US8003361B2 (en) 2007-10-01 2011-08-23 Cargill Incorporated Production of monatin enantiomers
EP2107053A1 (de) * 2008-03-11 2009-10-07 Ajinomoto Co., Inc. Hydratkristalle von (2R,4R)-Monatin Mononatrium-Salz
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US8771997B2 (en) 2011-04-20 2014-07-08 Ajinomoto Co., Inc. Method for producing monatin using an L-amino acid aminotransferase
CN115806481B (zh) * 2022-12-05 2024-11-22 安徽丰乐香料有限责任公司 L-薄荷基甲酸的分离提纯方法
CN119775157B (zh) * 2024-12-11 2025-09-19 西安味品荟食品科技有限公司 一种呈味化合物及其制备方法及应用

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US7297800B2 (en) 2001-12-27 2007-11-20 Ajinomoto Co., Inc. Process of producing glutamate derivatives
CN100465156C (zh) 2001-12-27 2009-03-04 味之素株式会社 谷氨酸化合物及其制备中间体的制造方法与为此所用的新型中间体
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US7572607B2 (en) 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
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AU2003289264A1 (en) 2002-12-09 2004-06-30 Ajinomoto Co., Inc. Mutant d-aminotransferase and process for producing optically active glutamic acid derivative using the same
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US7935377B2 (en) 2004-06-04 2011-05-03 Ajinomoto Co., Inc. Crystals of free (2R, 4R)-monatin and use thereof
CA2506247C (en) 2004-06-07 2012-02-21 Ajinomoto Co., Inc. Novel aldolase, and method for producing optically active ihog and monatin
KR101216575B1 (ko) * 2004-07-14 2012-12-31 아지노모토 가부시키가이샤 (2ｒ,4ｒ)-모나틴 칼륨 염 결정 및 이를 함유하는 감미료조성물
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JPWO2006038520A1 (ja) 2004-10-05 2008-05-15 味の素株式会社 ヒドロキシイミノ酸からのアミノ酸誘導体製造方法
CN101035442B (zh) * 2004-10-15 2012-04-11 味之素株式会社 甜味剂组合物
CN101239941B (zh) 2007-02-08 2012-02-29 味之素株式会社 光学活性化合物的制造方法
EP2107053A1 (de) * 2008-03-11 2009-10-07 Ajinomoto Co., Inc. Hydratkristalle von (2R,4R)-Monatin Mononatrium-Salz

Also Published As

Publication number Publication date
US20100105924A1 (en) 2010-04-29
US7868187B2 (en) 2011-01-11
JP4905426B2 (ja) 2012-03-28
US7390909B2 (en) 2008-06-24
CN101450907B (zh) 2013-07-17
US20050004394A1 (en) 2005-01-06
KR100906947B1 (ko) 2009-07-09
ES2383518T3 (es) 2012-06-21
JP4196832B2 (ja) 2008-12-17
US7678925B2 (en) 2010-03-16
US20060074249A1 (en) 2006-04-06
US7064219B2 (en) 2006-06-20
US20120035373A1 (en) 2012-02-09
EP1466890A4 (de) 2005-01-26
US20090259052A1 (en) 2009-10-15
WO2003059865A1 (en) 2003-07-24
CN101450907A (zh) 2009-06-10
CA2471847A1 (en) 2003-07-24
AU2002349606A1 (en) 2003-07-30
JP2009046488A (ja) 2009-03-05
KR20040076269A (ko) 2004-08-31
CN1610658A (zh) 2005-04-27
US20080091032A1 (en) 2008-04-17
CA2471847C (en) 2012-05-15
EP1466890A1 (de) 2004-10-13
EP1466890B1 (de) 2012-04-04
JPWO2003059865A1 (ja) 2005-05-19
CN100465156C (zh) 2009-03-04

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