ATE499353T1 - Verfahren zur herstellung von taxanderivaten - Google Patents
Verfahren zur herstellung von taxanderivatenInfo
- Publication number
- ATE499353T1 ATE499353T1 AT01924282T AT01924282T ATE499353T1 AT E499353 T1 ATE499353 T1 AT E499353T1 AT 01924282 T AT01924282 T AT 01924282T AT 01924282 T AT01924282 T AT 01924282T AT E499353 T1 ATE499353 T1 AT E499353T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- derivatives
- taxand
- taxane
- novel
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 3
- HOJZAHQWDXAPDJ-UHFFFAOYSA-N 3-anilino-2-hydroxypropanoic acid Chemical class OC(=O)C(O)CNC1=CC=CC=C1 HOJZAHQWDXAPDJ-UHFFFAOYSA-N 0.000 abstract 1
- 229940123237 Taxane Drugs 0.000 abstract 1
- 150000004200 baccatin III derivatives Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 238000010189 synthetic method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2001/009348 WO2002076967A1 (en) | 2001-03-23 | 2001-03-23 | Process for making taxane derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE499353T1 true ATE499353T1 (de) | 2011-03-15 |
Family
ID=21742432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01924282T ATE499353T1 (de) | 2001-03-23 | 2001-03-23 | Verfahren zur herstellung von taxanderivaten |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1383754B1 (de) |
| JP (1) | JP4108483B2 (de) |
| CN (1) | CN100432064C (de) |
| AT (1) | ATE499353T1 (de) |
| DE (2) | DE60144113D1 (de) |
| DK (1) | DK1383754T3 (de) |
| ES (1) | ES2285967T3 (de) |
| WO (1) | WO2002076967A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1961735B1 (de) * | 2007-02-22 | 2009-11-18 | Indena S.P.A. | Verfahren zur Herstellung von (2r,3s)-3-Phenylisoserin-Methylester-Acetatsalz |
| CN107848990B (zh) * | 2015-07-07 | 2021-06-11 | 万代忠胜 | 紫杉醇和多烯紫杉醇的侧链前体的制造方法 |
| CN109206331A (zh) * | 2018-09-17 | 2019-01-15 | 康化(上海)新药研发有限公司 | 一种2-甲基丝氨酸的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2696459B1 (fr) * | 1992-10-05 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé de préparation de dérivés du taxane. |
| FR2696460B1 (fr) * | 1992-10-05 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé de préparation de dérivés du taxane. |
| ATE253563T1 (de) * | 1993-02-05 | 2003-11-15 | Bryn Mawr College | Synthese von taxol, seinen analogen und intermediaten mit variablen a-ring seitenketten |
| ES2205663T3 (es) * | 1993-06-11 | 2004-05-01 | PHARMACIA & UPJOHN COMPANY | Uso antineoplasico de delta 6,7-taxoles y composiciones farmaceuticas que los contienen. |
-
2001
- 2001-03-23 DE DE60144113T patent/DE60144113D1/de not_active Expired - Lifetime
- 2001-03-23 EP EP01924282A patent/EP1383754B1/de not_active Expired - Lifetime
- 2001-03-23 JP JP2002576226A patent/JP4108483B2/ja not_active Expired - Fee Related
- 2001-03-23 DK DK01924282.5T patent/DK1383754T3/da active
- 2001-03-23 ES ES01924282T patent/ES2285967T3/es not_active Expired - Lifetime
- 2001-03-23 CN CNB018232884A patent/CN100432064C/zh not_active Expired - Fee Related
- 2001-03-23 DE DE01924282T patent/DE01924282T1/de active Pending
- 2001-03-23 WO PCT/US2001/009348 patent/WO2002076967A1/en not_active Ceased
- 2001-03-23 AT AT01924282T patent/ATE499353T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002076967A1 (en) | 2002-10-03 |
| CN1511146A (zh) | 2004-07-07 |
| DK1383754T3 (da) | 2011-04-04 |
| DE60144113D1 (de) | 2011-04-07 |
| CN100432064C (zh) | 2008-11-12 |
| EP1383754A1 (de) | 2004-01-28 |
| JP2004531498A (ja) | 2004-10-14 |
| ES2285967T3 (es) | 2011-06-07 |
| EP1383754A4 (de) | 2005-08-10 |
| ES2285967T1 (es) | 2007-12-01 |
| DE01924282T1 (de) | 2007-04-19 |
| EP1383754B1 (de) | 2011-02-23 |
| JP4108483B2 (ja) | 2008-06-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |