ATE500826T1 - Verwendung von azabicyclohexan-derivaten - Google Patents

Verwendung von azabicyclohexan-derivaten

Info

Publication number
ATE500826T1
ATE500826T1 AT06777058T AT06777058T ATE500826T1 AT E500826 T1 ATE500826 T1 AT E500826T1 AT 06777058 T AT06777058 T AT 06777058T AT 06777058 T AT06777058 T AT 06777058T AT E500826 T1 ATE500826 T1 AT E500826T1
Authority
AT
Austria
Prior art keywords
disorder
nervosa
hyperchondriasis
sydeham
paraphilia
Prior art date
Application number
AT06777058T
Other languages
English (en)
Inventor
Dieter Hamprecht
Christian Heidbreder
Sergio Melotto
Fabrizio Micheli
Tadataka Yamada
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE500826T1 publication Critical patent/ATE500826T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Liquid Crystal Substances (AREA)
AT06777058T 2005-08-22 2006-08-21 Verwendung von azabicyclohexan-derivaten ATE500826T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0517193.9A GB0517193D0 (en) 2005-08-22 2005-08-22 Novel use
PCT/EP2006/008314 WO2007022980A1 (en) 2005-08-22 2006-08-21 Use of azabicyclo hexane derivatives

Publications (1)

Publication Number Publication Date
ATE500826T1 true ATE500826T1 (de) 2011-03-15

Family

ID=35098098

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06777058T ATE500826T1 (de) 2005-08-22 2006-08-21 Verwendung von azabicyclohexan-derivaten

Country Status (20)

Country Link
US (2) US20090036461A1 (de)
EP (1) EP1917013B1 (de)
JP (1) JP5166267B2 (de)
KR (1) KR101363090B1 (de)
CN (1) CN101291669B (de)
AT (1) ATE500826T1 (de)
AU (1) AU2006284077B2 (de)
BR (1) BRPI0614929A2 (de)
CA (1) CA2620090A1 (de)
CR (1) CR9807A (de)
DE (1) DE602006020589D1 (de)
EA (1) EA016084B1 (de)
ES (1) ES2361933T3 (de)
GB (1) GB0517193D0 (de)
IL (1) IL189435A0 (de)
MA (1) MA29774B1 (de)
MX (1) MX2008002564A (de)
NO (1) NO20081314L (de)
WO (1) WO2007022980A1 (de)
ZA (1) ZA200801352B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1745040B9 (de) * 2004-02-23 2010-06-02 Glaxo Group Limited Als modulatoren des dopamin-d3-rezeptors geeignete azabicyclo[3.1.0]hexanderivate
US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
GB0507601D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507602D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
JP5068747B2 (ja) * 2005-06-14 2012-11-07 グラクソ グループ リミテッド ドーパミンd3受容体のモジュレーターとしてのアザビシクロ[3.1.0]ヘキサン誘導体
GB0512099D0 (en) * 2005-06-14 2005-07-20 Glaxo Group Ltd Compounds
RU2008107336A (ru) 2005-07-27 2009-09-10 Дов Фармасьютикал, Инк. (Us) Новые 1-арил-з-азабицикло{3.1.0.} гексаны: получение и применение для лечения психоневрологических расстройств
JP5237807B2 (ja) * 2005-08-22 2013-07-17 グラクソ グループ リミテッド ドーパミンd3受容体の調節因子としてのトリアゾール誘導体
GB0517191D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517187D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517175D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
DE602007012531D1 (de) * 2006-04-03 2011-03-31 Glaxo Group Ltd Azabicycloä3.1.0ühexanderivate als modulatoren von dopamin-d3-rezeptoren
EP2007751B1 (de) * 2006-04-03 2013-08-21 Glaxo Group Limited Azabicyclo[3.1.0]hexylderivate als modulatoren von dopamin-d3-rezeptoren
GB0607899D0 (en) 2006-04-03 2006-05-31 Glaxo Group Ltd Process for preparing heterocyclic derivatives
US20080045725A1 (en) 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
GB0616574D0 (en) * 2006-08-21 2006-09-27 Glaxo Group Ltd Compounds
US8138377B2 (en) 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
WO2008153937A2 (en) * 2007-06-06 2008-12-18 Dov Pharmaceutical, Inc. Novel 1- heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
BR112012000657A2 (pt) * 2009-06-26 2016-11-16 Panacea Biotec Ltd novos azabicilohexanos
WO2012033956A1 (en) 2010-09-08 2012-03-15 Mithridion, Inc. Cognition enhancing compounds and compositions, methods of making, and methods of treating
US20140206740A1 (en) 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters
US9314600B2 (en) 2012-04-15 2016-04-19 Bioconnect Systems, Inc. Delivery system for implantable flow connector
JP7250405B2 (ja) 2018-01-26 2023-04-03 塩野義製薬株式会社 ドーパミンd3受容体拮抗作用を有する環式化合物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI244481B (en) * 1998-12-23 2005-12-01 Pfizer 3-azabicyclo[3.1.0]hexane derivatives useful in therapy
US20020103198A1 (en) * 2000-12-04 2002-08-01 Fliri Anton F.J Acylamino cyclopropane derivatives
EP1745040B9 (de) * 2004-02-23 2010-06-02 Glaxo Group Limited Als modulatoren des dopamin-d3-rezeptors geeignete azabicyclo[3.1.0]hexanderivate
SE526837C2 (sv) * 2004-02-24 2005-11-08 Kongsberg Automotive Asa Växelspakstransmission
WO2006058753A1 (en) * 2004-12-02 2006-06-08 Abbott Gmbh & Co. Kg Triazole compounds suitable for treating disorders that respond to modulaiont of the dopamine d3 receptor
GB0507602D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507601D0 (en) 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507680D0 (en) * 2005-04-15 2005-05-25 Glaxo Group Ltd Compounds
GB0512099D0 (en) * 2005-06-14 2005-07-20 Glaxo Group Ltd Compounds
JP5068747B2 (ja) * 2005-06-14 2012-11-07 グラクソ グループ リミテッド ドーパミンd3受容体のモジュレーターとしてのアザビシクロ[3.1.0]ヘキサン誘導体
GB0517175D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
JP5237807B2 (ja) * 2005-08-22 2013-07-17 グラクソ グループ リミテッド ドーパミンd3受容体の調節因子としてのトリアゾール誘導体
GB0517191D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517187D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
US7727988B2 (en) * 2006-04-03 2010-06-01 Glaxo Group Limited Azabicyclo[3.1.0]hex-3-yl}alkyl)pyrimidinedione
GB0616574D0 (en) * 2006-08-21 2006-09-27 Glaxo Group Ltd Compounds

Also Published As

Publication number Publication date
KR20080040022A (ko) 2008-05-07
EP1917013B1 (de) 2011-03-09
EA200800655A1 (ru) 2008-08-29
NO20081314L (no) 2008-03-17
ES2361933T3 (es) 2011-06-24
US20090036461A1 (en) 2009-02-05
ZA200801352B (en) 2009-01-28
AU2006284077B2 (en) 2012-05-17
EA016084B1 (ru) 2012-02-28
MA29774B1 (fr) 2008-09-01
CA2620090A1 (en) 2007-03-01
US20120196910A1 (en) 2012-08-02
DE602006020589D1 (de) 2011-04-21
MX2008002564A (es) 2008-03-18
EP1917013A1 (de) 2008-05-07
GB0517193D0 (en) 2005-09-28
WO2007022980A1 (en) 2007-03-01
JP5166267B2 (ja) 2013-03-21
CR9807A (es) 2008-07-29
CN101291669B (zh) 2012-09-26
IL189435A0 (en) 2008-08-07
KR101363090B1 (ko) 2014-02-13
BRPI0614929A2 (pt) 2011-04-19
CN101291669A (zh) 2008-10-22
JP2009506989A (ja) 2009-02-19
AU2006284077A1 (en) 2007-03-01

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