CR9807A - Uso de derivados de azabiciclohexano - Google Patents

Uso de derivados de azabiciclohexano

Info

Publication number
CR9807A
CR9807A CR9807A CR9807A CR9807A CR 9807 A CR9807 A CR 9807A CR 9807 A CR9807 A CR 9807A CR 9807 A CR9807 A CR 9807A CR 9807 A CR9807 A CR 9807A
Authority
CR
Costa Rica
Prior art keywords
disorder
azabiciclohexano
derivatives
nervosa
hyperchondriasis
Prior art date
Application number
CR9807A
Other languages
English (en)
Inventor
Hamprecht Dieter
Heidbreder Christian
Melotto Sergio
Micheli Fabrizio
Yamada Tadataka
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of CR9807A publication Critical patent/CR9807A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Liquid Crystal Substances (AREA)

Abstract

La presente invencion provee un nuevo uso de un compuesto de la formula (I) o una sal o solvato farmaceuticamente aceptable del mismo: en donde: G se selecciona del grupo que consiste de: fenilo, piridilo, benzotiazolilo, indazolilo; p es un entero que varia de 0 a 5; R1 se selecciona independientemente de un grupo que consiste de halogeno, hidroxi, ciano, alquilo de C1-4, haogenoalquilo de C1-4, alcoxi de C1-4, halogenoalcoxi de C1-4, alcanoilo de C1-4; o corresponde a un grupo de R5; R2 es hidrogeno o alquilo de C1-4; R3 es alquilo de C1-4.
CR9807A 2005-08-22 2008-03-11 Uso de derivados de azabiciclohexano CR9807A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0517193.9A GB0517193D0 (en) 2005-08-22 2005-08-22 Novel use

Publications (1)

Publication Number Publication Date
CR9807A true CR9807A (es) 2008-07-29

Family

ID=35098098

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9807A CR9807A (es) 2005-08-22 2008-03-11 Uso de derivados de azabiciclohexano

Country Status (20)

Country Link
US (2) US20090036461A1 (es)
EP (1) EP1917013B1 (es)
JP (1) JP5166267B2 (es)
KR (1) KR101363090B1 (es)
CN (1) CN101291669B (es)
AT (1) ATE500826T1 (es)
AU (1) AU2006284077B2 (es)
BR (1) BRPI0614929A2 (es)
CA (1) CA2620090A1 (es)
CR (1) CR9807A (es)
DE (1) DE602006020589D1 (es)
EA (1) EA016084B1 (es)
ES (1) ES2361933T3 (es)
GB (1) GB0517193D0 (es)
IL (1) IL189435A0 (es)
MA (1) MA29774B1 (es)
MX (1) MX2008002564A (es)
NO (1) NO20081314L (es)
WO (1) WO2007022980A1 (es)
ZA (1) ZA200801352B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1745040B9 (en) * 2004-02-23 2010-06-02 Glaxo Group Limited Azabicyclo(3.1.0) hexane derivatives useful as modulators of dopamine d3 receptors
US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
GB0507601D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507602D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
JP5068747B2 (ja) * 2005-06-14 2012-11-07 グラクソ グループ リミテッド ドーパミンｄ３受容体のモジュレーターとしてのアザビシクロ［３．１．０］ヘキサン誘導体
GB0512099D0 (en) * 2005-06-14 2005-07-20 Glaxo Group Ltd Compounds
RU2008107336A (ru) 2005-07-27 2009-09-10 Дов Фармасьютикал, Инк. (Us) Новые 1-арил-з-азабицикло{3.1.0.} гексаны: получение и применение для лечения психоневрологических расстройств
JP5237807B2 (ja) * 2005-08-22 2013-07-17 グラクソ グループ リミテッド ドーパミンｄ３受容体の調節因子としてのトリアゾール誘導体
GB0517191D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517187D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517175D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
DE602007012531D1 (de) * 2006-04-03 2011-03-31 Glaxo Group Ltd Azabicycloä3.1.0ühexanderivate als modulatoren von dopamin-d3-rezeptoren
EP2007751B1 (en) * 2006-04-03 2013-08-21 Glaxo Group Limited Azabicyclo [3. 1. o] hexyl derivatives as modulators of dopamine d3 receptors
GB0607899D0 (en) 2006-04-03 2006-05-31 Glaxo Group Ltd Process for preparing heterocyclic derivatives
US20080045725A1 (en) 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
GB0616574D0 (en) * 2006-08-21 2006-09-27 Glaxo Group Ltd Compounds
US8138377B2 (en) 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
WO2008153937A2 (en) * 2007-06-06 2008-12-18 Dov Pharmaceutical, Inc. Novel 1- heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
BR112012000657A2 (pt) * 2009-06-26 2016-11-16 Panacea Biotec Ltd novos azabicilohexanos
WO2012033956A1 (en) 2010-09-08 2012-03-15 Mithridion, Inc. Cognition enhancing compounds and compositions, methods of making, and methods of treating
US20140206740A1 (en) 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters
US9314600B2 (en) 2012-04-15 2016-04-19 Bioconnect Systems, Inc. Delivery system for implantable flow connector
JP7250405B2 (ja) 2018-01-26 2023-04-03 塩野義製薬株式会社 ドーパミンｄ３受容体拮抗作用を有する環式化合物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI244481B (en) * 1998-12-23 2005-12-01 Pfizer 3-azabicyclo[3.1.0]hexane derivatives useful in therapy
US20020103198A1 (en) * 2000-12-04 2002-08-01 Fliri Anton F.J Acylamino cyclopropane derivatives
EP1745040B9 (en) * 2004-02-23 2010-06-02 Glaxo Group Limited Azabicyclo(3.1.0) hexane derivatives useful as modulators of dopamine d3 receptors
SE526837C2 (sv) * 2004-02-24 2005-11-08 Kongsberg Automotive Asa Växelspakstransmission
WO2006058753A1 (en) * 2004-12-02 2006-06-08 Abbott Gmbh & Co. Kg Triazole compounds suitable for treating disorders that respond to modulaiont of the dopamine d3 receptor
GB0507602D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507601D0 (en) 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507680D0 (en) * 2005-04-15 2005-05-25 Glaxo Group Ltd Compounds
GB0512099D0 (en) * 2005-06-14 2005-07-20 Glaxo Group Ltd Compounds
JP5068747B2 (ja) * 2005-06-14 2012-11-07 グラクソ グループ リミテッド ドーパミンｄ３受容体のモジュレーターとしてのアザビシクロ［３．１．０］ヘキサン誘導体
GB0517175D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
JP5237807B2 (ja) * 2005-08-22 2013-07-17 グラクソ グループ リミテッド ドーパミンｄ３受容体の調節因子としてのトリアゾール誘導体
GB0517191D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517187D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
US7727988B2 (en) * 2006-04-03 2010-06-01 Glaxo Group Limited Azabicyclo[3.1.0]hex-3-yl}alkyl)pyrimidinedione
GB0616574D0 (en) * 2006-08-21 2006-09-27 Glaxo Group Ltd Compounds

Also Published As

Publication number Publication date
KR20080040022A (ko) 2008-05-07
EP1917013B1 (en) 2011-03-09
EA200800655A1 (ru) 2008-08-29
ATE500826T1 (de) 2011-03-15
NO20081314L (no) 2008-03-17
ES2361933T3 (es) 2011-06-24
US20090036461A1 (en) 2009-02-05
ZA200801352B (en) 2009-01-28
AU2006284077B2 (en) 2012-05-17
EA016084B1 (ru) 2012-02-28
MA29774B1 (fr) 2008-09-01
CA2620090A1 (en) 2007-03-01
US20120196910A1 (en) 2012-08-02
DE602006020589D1 (de) 2011-04-21
MX2008002564A (es) 2008-03-18
EP1917013A1 (en) 2008-05-07
GB0517193D0 (en) 2005-09-28
WO2007022980A1 (en) 2007-03-01
JP5166267B2 (ja) 2013-03-21
CN101291669B (zh) 2012-09-26
IL189435A0 (en) 2008-08-07
KR101363090B1 (ko) 2014-02-13
BRPI0614929A2 (pt) 2011-04-19
CN101291669A (zh) 2008-10-22
JP2009506989A (ja) 2009-02-19
AU2006284077A1 (en) 2007-03-01

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)