ATE501120T1 - Verfahren zur herstellung von isoindolderivaten - Google Patents
Verfahren zur herstellung von isoindolderivatenInfo
- Publication number
- ATE501120T1 ATE501120T1 AT05766977T AT05766977T ATE501120T1 AT E501120 T1 ATE501120 T1 AT E501120T1 AT 05766977 T AT05766977 T AT 05766977T AT 05766977 T AT05766977 T AT 05766977T AT E501120 T1 ATE501120 T1 AT E501120T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- isoindole derivatives
- salt
- compound
- following general
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 150000002518 isoindoles Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000000904 isoindolyl group Chemical class C=1(NC=C2C=CC=CC12)* 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
- C07C255/59—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004236645 | 2004-08-16 | ||
| PCT/JP2005/013696 WO2006018955A1 (ja) | 2004-08-16 | 2005-07-27 | イソインドール誘導体の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE501120T1 true ATE501120T1 (de) | 2011-03-15 |
Family
ID=35907346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05766977T ATE501120T1 (de) | 2004-08-16 | 2005-07-27 | Verfahren zur herstellung von isoindolderivaten |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7585982B2 (de) |
| EP (1) | EP1787983B1 (de) |
| JP (1) | JP4820295B2 (de) |
| KR (1) | KR20070062520A (de) |
| CN (1) | CN101056853B (de) |
| AT (1) | ATE501120T1 (de) |
| AU (1) | AU2005273430B2 (de) |
| CA (1) | CA2576952A1 (de) |
| DE (1) | DE602005026827D1 (de) |
| IL (1) | IL181196A (de) |
| WO (1) | WO2006018955A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4549970B2 (ja) | 2003-02-19 | 2010-09-22 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 環状ベンズアミジン誘導体の製造方法 |
| JP4787757B2 (ja) * | 2004-08-17 | 2011-10-05 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ジブロモフルオロベンゼン誘導体の製造方法 |
| US7786330B2 (en) | 2005-02-28 | 2010-08-31 | Asahi Glass Company, Limited | Process for producing 1,2-dialkoxy-3-fluorobenzene |
| JPWO2008023438A1 (ja) | 2006-08-25 | 2010-01-07 | 旭硝子株式会社 | １，２−ジアルコキシ−３−フルオロベンゼンの製造方法 |
| SI2242740T1 (sl) | 2008-02-05 | 2013-03-29 | Sanofi | SF5-derivati kot PAR1 inhibitorji, njihova priprava in uporaba kot zdravila |
| US8673890B2 (en) * | 2009-10-29 | 2014-03-18 | Janssen Pharmaceutica Nv | 2,3-dihydro-1H-isoindol-1-imine derivatives useful as thrombin PAR-1 receptor antagonist |
| JPWO2012014889A1 (ja) * | 2010-07-29 | 2013-09-12 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | フタロニトリル誘導体の製造方法 |
| HK1254827A1 (zh) | 2016-05-04 | 2019-07-26 | 上海研健新药研发有限公司 | 一种钠依赖性葡萄糖共转运蛋白抑制剂的胺溶剂合物及其制备方法和应用 |
| CN106083692B (zh) * | 2016-05-26 | 2019-04-26 | 苏州大学 | 一种2-(2-芳基异吲哚-1-亚基)丙二腈类化合物的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2805535B1 (fr) * | 2000-02-25 | 2002-04-12 | Adir | Nouveau procede de preparation de l'isoindoline |
| US7476688B2 (en) * | 2001-04-19 | 2009-01-13 | Eisai R&D Management Co., Ltd. | Cyclic amidine derivatives |
| JP4549970B2 (ja) | 2003-02-19 | 2010-09-22 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 環状ベンズアミジン誘導体の製造方法 |
| JP4787757B2 (ja) | 2004-08-17 | 2011-10-05 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ジブロモフルオロベンゼン誘導体の製造方法 |
-
2005
- 2005-07-27 KR KR1020077006153A patent/KR20070062520A/ko not_active Abandoned
- 2005-07-27 AU AU2005273430A patent/AU2005273430B2/en not_active Ceased
- 2005-07-27 DE DE602005026827T patent/DE602005026827D1/de not_active Expired - Lifetime
- 2005-07-27 CN CN2005800348659A patent/CN101056853B/zh not_active Expired - Fee Related
- 2005-07-27 JP JP2006531410A patent/JP4820295B2/ja not_active Expired - Fee Related
- 2005-07-27 CA CA002576952A patent/CA2576952A1/en not_active Abandoned
- 2005-07-27 AT AT05766977T patent/ATE501120T1/de not_active IP Right Cessation
- 2005-07-27 EP EP05766977A patent/EP1787983B1/de not_active Expired - Lifetime
- 2005-07-27 US US11/573,814 patent/US7585982B2/en not_active Expired - Fee Related
- 2005-07-27 WO PCT/JP2005/013696 patent/WO2006018955A1/ja not_active Ceased
-
2007
- 2007-02-07 IL IL181196A patent/IL181196A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1787983B1 (de) | 2011-03-09 |
| JPWO2006018955A1 (ja) | 2008-05-08 |
| KR20070062520A (ko) | 2007-06-15 |
| EP1787983A4 (de) | 2009-06-24 |
| JP4820295B2 (ja) | 2011-11-24 |
| US7585982B2 (en) | 2009-09-08 |
| DE602005026827D1 (de) | 2011-04-21 |
| IL181196A0 (en) | 2007-07-04 |
| CA2576952A1 (en) | 2006-02-23 |
| CN101056853A (zh) | 2007-10-17 |
| CN101056853B (zh) | 2010-05-05 |
| AU2005273430B2 (en) | 2011-06-30 |
| WO2006018955A1 (ja) | 2006-02-23 |
| IL181196A (en) | 2012-06-28 |
| US20080214834A1 (en) | 2008-09-04 |
| EP1787983A1 (de) | 2007-05-23 |
| AU2005273430A1 (en) | 2006-02-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |