ATE507205T1 - Aromatische 1,4-di-carboxylamide und deren verwendung - Google Patents

Aromatische 1,4-di-carboxylamide und deren verwendung

Info

Publication number: ATE507205T1
Authority: AT; Austria
Prior art keywords: group; branched; alkyl; stands; hydroxyl
Prior art date: 2006-12-11

Application number

AT06025620T

Other languages

English (en)

Inventor

Gabriel Garcia

Pierre Daram

Barbara Froesch

Guy Lemaillet

Leonardo Scapozza

Original Assignee

Genetics Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-12-11

Filing date

2006-12-11

Publication date

2011-05-15

2006-12-11 Application filed by Genetics Co Inc filed Critical Genetics Co Inc

2011-05-15 Application granted granted Critical

2011-05-15 Publication of ATE507205T1 publication Critical patent/ATE507205T1/de

Links

-1 1,3-dioxolyl Chemical group 0.000 abstract 5
229910052799 carbon Inorganic materials 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
125000002541 furyl group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
229910052757 nitrogen Inorganic materials 0.000 abstract 2
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000006527 (C1-C5) alkyl group Chemical group 0.000 abstract 1
125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 abstract 1
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000002723 alicyclic group Chemical group 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000004122 cyclic group Chemical group 0.000 abstract 1
125000000596 cyclohexenyl group Chemical group C1(=CCCCC1)* 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000002183 isoquinolinyl group Chemical group C1(=NC=CC2=CC=CC=C12)* 0.000 abstract 1
125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
125000002757 morpholinyl group Chemical group 0.000 abstract 1
125000001624 naphthyl group Chemical group 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
125000002943 quinolinyl group Chemical group N1=C(C=CC2=CC=CC=C12)* 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
125000003039 tetrahydroisoquinolinyl group Chemical group C1(NCCC2=CC=CC=C12)* 0.000 abstract 1
125000000147 tetrahydroquinolinyl group Chemical group N1(CCCC2=CC=CC=C12)* 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/96—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Transplantation (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Dermatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Hematology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pyridine Compounds (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT06025620T 2006-12-11 2006-12-11 Aromatische 1,4-di-carboxylamide und deren verwendung ATE507205T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP06025620A EP1932834B1 (de)	2006-12-11	2006-12-11	Aromatische 1,4-DI-Carboxylamide und deren Verwendung

Publications (1)

Publication Number	Publication Date
ATE507205T1 true ATE507205T1 (de)	2011-05-15

Family

ID=38162304

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06025620T ATE507205T1 (de)	2006-12-11	2006-12-11	Aromatische 1,4-di-carboxylamide und deren verwendung

Country Status (8)

Country	Link
US (1)	US20100204219A1 (de)
EP (2)	EP1932834B1 (de)
JP (1)	JP2010512357A (de)
KR (1)	KR20090087492A (de)
CN (1)	CN101583603B (de)
AT (1)	ATE507205T1 (de)
DE (1)	DE602006021591D1 (de)
WO (1)	WO2008071397A1 (de)

Families Citing this family (52)

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WO2008112164A2 (en)	2007-03-08	2008-09-18	The Board Of Trustees Of The Leland Stanford Junior University	Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof
EP2337563B1 (de)	2008-09-08	2014-04-09	The Board of Trustees of The Leland Stanford Junior University	Modulatoren der aldehyddehydrogenase-aktivität und anwendungsverfahren für diese
JP2012506856A (ja)	2008-10-28	2012-03-22	ボードオブトラスティーズオブザレランドスタンフォードジュニアユニバーシティ	アルデヒドデヒドロゲナーゼのモジュレーターおよびその使用方法
CN102365275B (zh)	2009-01-28	2014-09-24	里格尔药品股份有限公司	羧酰胺化合物及其使用方法
EP2464232B1 (de)	2009-08-10	2015-10-07	Samumed, LLC	Indazolhemmer des wnt-signalpfades und therapeutische anwendungen davon
SMT201700581T1 (it)	2009-12-21	2018-01-11	Samumed Llc	1h-pirazolo[3,4-b]piridine e loro usi terapeutici
KR101764952B1 (ko)	2010-07-29	2017-08-03	리겔 파마슈티칼스, 인크.	Ａｍｐｋ-활성화 헤테로시클릭 화합물 및 그의 사용 방법
AU2012308570B2 (en)	2011-09-14	2016-11-10	Samumed, Llc	Indazole-3-carboxamides and their use as Wnt/b-catenin signaling pathway inhibitors
PH12017500997A1 (en)	2012-04-04	2018-02-19	Samumed Llc	Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof
ME03573B (de)	2012-05-04	2020-07-20	Samumed Llc	1h-pyrazolo[3,4-beta]pyridine und therapeutische verwendung davon
CN105120862A (zh)	2013-01-08	2015-12-02	萨穆梅德有限公司	Wnt信号途径的3-(苯并咪唑-2-基)-吲唑抑制剂及其治疗应用
WO2014160185A2 (en)	2013-03-14	2014-10-02	The Board Of Trustees Of The Leland Stanford Junior University	Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof
US10130633B2 (en) *	2013-03-20	2018-11-20	Bayer Pharma Aktiengesellschaft	Compounds
JP2016521259A (ja) *	2013-03-20	2016-07-21	バイエル・ファルマ・アクティエンゲゼルシャフト	置換Ｎ−ビフェニル−３−アセチルアミノ−ベンズアミドおよびＮ−［３−（アセチルアミノ）フェニル］−ビフェニル−カルボキサミドならびにＷｎｔシグナル伝達経路の阻害剤としてのそれらの使用
MA39761A (fr) *	2014-03-20	2017-01-25	Bayer Pharma AG	Inhibiteurs des voies de signalisation wnt
WO2016040181A1 (en)	2014-09-08	2016-03-17	Samumed, Llc	3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016040193A1 (en)	2014-09-08	2016-03-17	Samumed, Llc	3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
WO2016040184A1 (en)	2014-09-08	2016-03-17	Samumed, Llc	3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016040185A1 (en)	2014-09-08	2016-03-17	Samumed, Llc	2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof
WO2016040182A1 (en)	2014-09-08	2016-03-17	Samumed, Llc	2-(1h-indazol-3-yl)-1h-imidazo[4,5-c]pyridine and therapeutic uses thereof
WO2016040188A1 (en)	2014-09-08	2016-03-17	Samumed, Llc	3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
WO2016040190A1 (en)	2014-09-08	2016-03-17	Samumed, Llc	3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
WO2016040180A1 (en)	2014-09-08	2016-03-17	Samumed, Llc	3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
JP2018507212A (ja) *	2015-02-20	2018-03-15	バイエル・ファルマ・アクティエンゲゼルシャフト	Ｎ−フェニル−（モルホリン−４−イルまたはピペラジニル）アセトアミド誘導体およびｗｎｔシグナル伝達経路の阻害剤としてのその使用
US20180092866A1 (en) *	2015-04-15	2018-04-05	University Of Utah Research Foundation	Substituted n-([1,1'-biphenyl]-3-yl)-[1,1'-biphenyl]-3-carboxamide analogs as inhibitors for beta-catenin/b-cell lymphoma 9 interactions
US10709697B2 (en)	2015-07-16	2020-07-14	Emory University	Bis-amines, compositions, and uses related to CXCR4 inhibition
US10285983B2 (en)	2015-08-03	2019-05-14	Samumed, Llc	3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-B] pyridines and therapeutic uses thereof
WO2017023989A1 (en)	2015-08-03	2017-02-09	Samumed, Llc.	3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
US10604512B2 (en)	2015-08-03	2020-03-31	Samumed, Llc	3-(1H-indol-2-yl)-1H-indazoles and therapeutic uses thereof
US10383861B2 (en)	2015-08-03	2019-08-20	Sammumed, LLC	3-(1H-pyrrolo[2,3-C]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof
US10519169B2 (en)	2015-08-03	2019-12-31	Samumed, Llc	3-(1H-pyrrolo[2,3-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
WO2017024003A1 (en)	2015-08-03	2017-02-09	Samumed, Llc	3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
US10195185B2 (en)	2015-08-03	2019-02-05	Samumed, Llc	3-(1H-imidazo[4,5-C]pyridin-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
WO2017023980A1 (en)	2015-08-03	2017-02-09	Samumed, Llc.	3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof
US10226448B2 (en)	2015-08-03	2019-03-12	Samumed, Llc	3-(1H-pyrrolo[3,2-C]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridines and therapeutic uses thereof
WO2017024026A1 (en)	2015-08-03	2017-02-09	Samumed, Llc	3-(1h-indol-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof
WO2017023993A1 (en)	2015-08-03	2017-02-09	Samumed, Llc.	3-(1h-indol-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
US10206908B2 (en)	2015-08-03	2019-02-19	Samumed, Llc	3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof
WO2017023988A1 (en)	2015-08-03	2017-02-09	Samumed, Llc.	3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
US10463651B2 (en)	2015-08-03	2019-11-05	Samumed, Llc	3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1H-indazoles and therapeutic uses thereof
US10350199B2 (en)	2015-08-03	2019-07-16	Samumed, Llc	3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof
WO2017024015A1 (en)	2015-08-03	2017-02-09	Samumed, Llc.	3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
WO2017024004A1 (en)	2015-08-03	2017-02-09	Samumed, Llc.	3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
CN108473491A (zh)	2015-11-06	2018-08-31	萨穆梅德有限公司	2-(1h-吲唑-3-基)-3h-咪唑并[4,5-c]吡啶以及其抗炎用途
US11542254B2 (en)	2016-03-25	2023-01-03	Universisity Of Utah Research Foundation	Methods and composition of 4-substituted benzoylpiperazine-1-substituted carbonyls as beta-catenin/B-cell lymphoma 9 inhibitors
AR108325A1 (es)	2016-04-27	2018-08-08	Samumed Llc	Isoquinolin-3-il carboxamidas y preparación y uso de las mismas
DK3464285T3 (da)	2016-06-01	2022-12-19	Biosplice Therapeutics Inc	Fremgangsmåde til fremstilling af n-(5-(3-(7-(3-fluorphenyl)-3h-imidazo[4,5-c]pyridin-2-yl)-1h-indazol-5-yl)pyridin-3-yl)-3-methylbutanamid
CN106117078A (zh) *	2016-06-28	2016-11-16	东南大学	5‑硝基‑4‑羟基间苯二酰胺类化合物在制备抗肿瘤药物中的应用
EP3528808B1 (de)	2016-10-21	2021-10-06	BioSplice Therapeutics, Inc.	Verfahren zur verwendung von indazol-3-carboxamiden und deren verwendung als hemmer des wnt/b-catenin-signalwegs
MA46696A (fr)	2016-11-07	2019-09-11	Samumed Llc	Formulations injectables à dose unique prêtes à l'emploi
WO2019118961A1 (en) *	2017-12-15	2019-06-20	H. Lee Moffitt Cancer Center And Research Institute, Inc.	Inhibitors for the β-catenin/b-cell lymphoma 9 (bcl9) protein–protein interaction
CN117024318A (zh) *	2018-07-16	2023-11-10	四川科伦博泰生物医药股份有限公司	对芳基二甲酰胺类化合物、包含其的药物组合物、其制备方法及其用途

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US5512586A (en) *	1987-02-10	1996-04-30	Hoechst Aktiengesellschaft	Medicaments based on pyridine-2,4- and 2,5-dicarboxylic acid amides
DE3920029C2 (de) *	1988-06-30	1999-05-20	Clariant Finance Bvi Ltd	Farbstoffe zum Färben von Kunststoffen
GB9405347D0 (en) *	1994-03-18	1994-05-04	Agrevo Uk Ltd	Fungicides
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2006
- 2006-12-11 AT AT06025620T patent/ATE507205T1/de not_active IP Right Cessation
- 2006-12-11 DE DE602006021591T patent/DE602006021591D1/de active Active
- 2006-12-11 EP EP06025620A patent/EP1932834B1/de not_active Not-in-force
2007
- 2007-12-11 KR KR1020097013895A patent/KR20090087492A/ko not_active Withdrawn
- 2007-12-11 CN CN2007800457354A patent/CN101583603B/zh not_active Expired - Fee Related
- 2007-12-11 US US12/517,680 patent/US20100204219A1/en not_active Abandoned
- 2007-12-11 WO PCT/EP2007/010829 patent/WO2008071397A1/en not_active Ceased
- 2007-12-11 JP JP2009540651A patent/JP2010512357A/ja not_active Withdrawn
- 2007-12-11 EP EP07856577A patent/EP2125751A1/de not_active Withdrawn

Also Published As

Publication number	Publication date
WO2008071397A1 (en)	2008-06-19
US20100204219A1 (en)	2010-08-12
EP2125751A1 (de)	2009-12-02
CN101583603B (zh)	2012-05-30
CN101583603A (zh)	2009-11-18
DE602006021591D1 (de)	2011-06-09
JP2010512357A (ja)	2010-04-22
EP1932834A1 (de)	2008-06-18
KR20090087492A (ko)	2009-08-17
EP1932834B1 (de)	2011-04-27

Legal Events

Date	Code	Title	Description
2011-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE602006021591D1 (de)	2011-06-09	Aromatische 1,4-DI-Carboxylamide und deren Verwendung
MX2010002272A (es)	2010-08-09	4-(4-piridinil)-benzamidas y su uso como moduladores de la actividad de rho-cinasa (rock).
ES2655899T3 (es)	2018-02-22	Compuestos de pirazolo[1,5-a]pirimidina sustituidos como inhibidores de la Trk cinasa
EA200870358A1 (ru)	2009-02-27	2-(циклический амино) пиримидоновые производные в качестве ингибиторов tpk1
TW200639171A (en)	2006-11-16	Heterocyclic substituted phenyl methanones
ATE293101T1 (de)	2005-04-15	Piperidine zur verwendung als orexin rezeptor antagonisten
NO20074447L (no)	2007-10-18	Sykloheksylamider som dopamin D3, D2 og 5HT1A-antagonister
MX2010003445A (es)	2010-04-27	Derivados de nicotinamida, su preparacion y su uso terapeutico.
MX2009003802A (es)	2009-06-04	Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta-2 adrenergico.
NO20060975L (no)	2006-04-06	1-Benzoyl-piperazinderivater som glycin gjenopptaksinhibitorer for behandling av psykoser
NZ528851A (en)	2006-03-31	N-aroyl cyclic amines
NO20091590L (no)	2009-05-08	Heterocykliske amidforbindelser anvendbare som kinaseinhibitorer
MX2009008465A (es)	2009-08-20	Nuevas 2-aminooxazolinas como ligandos de taar1.
RU2012130959A (ru)	2014-03-27	Фенольные производные и их фармацевтическое или косметическое применение
WO2002089800A3 (en)	2004-05-06	N-aroyl cyclic amine derivatives as orexin receptor antagonists
MX2010001080A (es)	2010-03-01	Pirrolidin-aril-eteres como antagonistas de receptor de nk3.
MY148482A (en)	2013-04-30	Heterocyclic compound and pharmaceutical composition thereof
MX2009012041A (es)	2010-02-18	Derivados de 1,3-dihidroimidazol-2-tiona como inhibidores de dopamina-beta-hidroxilasa.
EA201071012A1 (ru)	2011-04-29	Производные азетидинов, способ их получения и применение их в терапии
HUP0103988A2 (en)	2003-05-28	New d3-dopamine receptor selective piperazine and piperidine compounds, process for their preparation, their and pharmaceutical compositions containing them
NO331165B1 (no)	2011-10-24	Derivater av dioksan-2-alkylkarbamater, fremgangsmate for fremstilling derav og anvendelse av de samme for fremstilling av medikamenter
AR056582A1 (es)	2007-10-10	COMPUESTOS DE PIRAZOLIL UREA CON ACTIVIDAD INHIBITORIA DE CINASA P38 Y FORMULACIoN FARMACÉUTICA QUE LO COMPRENDE
EP1961734A4 (de)	2009-03-25	Aminverbindung und deren verwendung für medizinische zwecke
EA200501148A1 (ru)	2006-04-28	Пиридилоксиметильные и бензизоксазольные азабициклические производные
MY137964A (en)	2009-04-30	Benzofuran derivative