ATE508738T1 - System zur beabstandeten abgabe von arzneimitteln - Google Patents
System zur beabstandeten abgabe von arzneimittelnInfo
- Publication number
- ATE508738T1 ATE508738T1 AT06019650T AT06019650T ATE508738T1 AT E508738 T1 ATE508738 T1 AT E508738T1 AT 06019650 T AT06019650 T AT 06019650T AT 06019650 T AT06019650 T AT 06019650T AT E508738 T1 ATE508738 T1 AT E508738T1
- Authority
- AT
- Austria
- Prior art keywords
- drug delivery
- delivery system
- present
- provides
- patient
- Prior art date
Links
- 229940126601 medicinal product Drugs 0.000 title 1
- 238000012377 drug delivery Methods 0.000 abstract 4
- 239000013543 active substance Substances 0.000 abstract 3
- 239000003472 antidiabetic agent Substances 0.000 abstract 3
- 229940125708 antidiabetic agent Drugs 0.000 abstract 3
- 206010012601 diabetes mellitus Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000037406 food intake Effects 0.000 abstract 1
- 235000012631 food intake Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN37MU2001 IN191539B (de) | 2001-01-12 | 2001-01-12 | |
| IN324MU2001 | 2001-04-10 | ||
| IN325MU2001 | 2001-04-10 | ||
| IN323MU2001 | 2001-04-10 | ||
| IN326MU2001 | 2001-04-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE508738T1 true ATE508738T1 (de) | 2011-05-15 |
Family
ID=27517736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06019650T ATE508738T1 (de) | 2001-01-12 | 2002-01-11 | System zur beabstandeten abgabe von arzneimitteln |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7964216B2 (de) |
| EP (2) | EP1738751B1 (de) |
| JP (1) | JP4633329B2 (de) |
| AT (1) | ATE508738T1 (de) |
| BR (1) | BRPI0206432A2 (de) |
| CA (2) | CA2434169C (de) |
| MX (1) | MXPA03006217A (de) |
| PL (1) | PL362687A1 (de) |
| WO (1) | WO2002055009A1 (de) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040156900A1 (en) * | 2001-04-10 | 2004-08-12 | Shanghvi Dilip Shantilal | Time pulsed release composition |
| ITFI20010230A1 (it) * | 2001-11-29 | 2003-05-29 | Menarini Int Operations Lu Sa | Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii |
| GB0203296D0 (en) | 2002-02-12 | 2002-03-27 | Glaxo Group Ltd | Novel composition |
| PL376577A1 (pl) | 2002-06-17 | 2006-01-09 | Themis Laboratories Private Limited | Wielowarstwowe tabletki zawierające tiazolidinedion i biguanidy oraz metody ich wytwarzania |
| AU2003281181A1 (en) * | 2002-07-11 | 2004-02-02 | Takeda Pharmaceutical Company Limited | Process for producing coated preparation |
| US8637512B2 (en) | 2002-07-29 | 2014-01-28 | Glaxo Group Limited | Formulations and method of treatment |
| WO2004067001A1 (ja) | 2003-01-29 | 2004-08-12 | Takeda Pharmaceutical Company Limited | 被覆製剤の製造法 |
| WO2004108067A2 (en) * | 2003-04-03 | 2004-12-16 | Sun Pharmaceutical Industries Limited | Programmed drug delivery system |
| TWI339586B (en) | 2003-10-31 | 2011-04-01 | Takeda Chemical Industries Ltd | Solid preparation comprising pioglitazone or salt thereof,glimpiride and polyoxyethylene sorbitan fatty acid ester |
| TW200716088A (en) * | 2005-04-15 | 2007-05-01 | Neurochem Int Ltd | Formulations and methods for treating amyloidosis |
| MXPA05009633A (es) * | 2005-09-08 | 2007-03-07 | Silanes Sa De Cv Lab | Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada. |
| US8187633B2 (en) * | 2005-11-03 | 2012-05-29 | Sun Pharma Advanced Research Company Limited | Controlled release coated tablets having prolonged gastric retention |
| WO2007131930A1 (en) * | 2006-05-13 | 2007-11-22 | Novo Nordisk A/S | Tablet formulation comprising repaglinide and metformin |
| CA2672602C (en) | 2006-12-18 | 2014-05-20 | Electronic Dietary Foods Inc. | Device for delivery of a substance |
| CA2677623C (en) * | 2007-02-09 | 2015-04-07 | Alphapharm Pty Ltd | A dosage form containing two or more active pharmaceutical ingredients in different physical forms |
| FR2918567B1 (fr) * | 2007-07-11 | 2012-08-03 | Pf Medicament | Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine. |
| US20090124587A1 (en) * | 2007-07-12 | 2009-05-14 | Auerbach Alan H | METHODS FOR TREATING CANCER USING 17alpha-HYDROXYLASE/C17,20-LYASE INHIBITORS |
| MX2010001071A (es) * | 2007-07-27 | 2010-03-09 | Depomed Inc | Formas de dosificacion retentivas gastricas pulsatiles. |
| US11974971B2 (en) | 2011-01-07 | 2024-05-07 | Anji Pharmaceuticals Inc. | Compositions and methods for treating metabolic disorders |
| US9211263B2 (en) | 2012-01-06 | 2015-12-15 | Elcelyx Therapeutics, Inc. | Compositions and methods of treating metabolic disorders |
| US9572784B2 (en) | 2011-01-07 | 2017-02-21 | Elcelyx Therapeutics, Inc. | Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk |
| US8796338B2 (en) | 2011-01-07 | 2014-08-05 | Elcelyx Therapeutics, Inc | Biguanide compositions and methods of treating metabolic disorders |
| US9480663B2 (en) | 2011-01-07 | 2016-11-01 | Elcelyx Therapeutics, Inc. | Biguanide compositions and methods of treating metabolic disorders |
| WO2012094636A2 (en) | 2011-01-07 | 2012-07-12 | Elcelyx Therapeutics, Inc. | Chemosensory receptor ligand-based therapies |
| US11759441B2 (en) | 2011-01-07 | 2023-09-19 | Anji Pharmaceuticals Inc. | Biguanide compositions and methods of treating metabolic disorders |
| CN104349773A (zh) | 2012-01-06 | 2015-02-11 | 埃尔舍利克斯治疗公司 | 用于治疗代谢性病症的组合物和方法 |
| BR112014016808B1 (pt) | 2012-01-06 | 2022-01-11 | Anji Pharma (Us) Llc | Uso de um composto de biguanida para a fabricação de um medicamento para baixar os níveis de glicose no sangue e para o tratamento de um distúrbio do metabolismo de glicose |
| US10835495B2 (en) | 2012-11-14 | 2020-11-17 | W. R. Grace & Co.-Conn. | Compositions containing a biologically active material and a non-ordered inorganic oxide material and methods of making and using the same |
| EP2941245B1 (de) * | 2013-01-05 | 2024-06-26 | Anji Pharmaceuticals Inc. | Biguanidformulierung mit verzögerter freisetzung |
| HUE066123T2 (hu) * | 2013-06-13 | 2024-07-28 | Akebia Therapeutics Inc | Készítmények és módszerek anémia kezelésére |
| CN104621714B (zh) * | 2014-12-04 | 2018-01-05 | 湖北中烟工业有限责任公司 | 一种提高脆性的烟用添加剂滴丸及其制备方法 |
| CN110882261A (zh) * | 2019-12-27 | 2020-03-17 | 无锡福祈制药有限公司 | 二甲双胍格列吡嗪制剂 |
| WO2021216530A1 (en) | 2020-04-20 | 2021-10-28 | Akebia Therapeutics, Inc. | Treatment of viral infections, of organ injury, and of related conditions using a hif prolyl hydroxylase inhibitor or a hif-alpha stabilizer |
| CN113143940A (zh) * | 2020-12-30 | 2021-07-23 | 成都恒瑞制药有限公司 | 一种抗糖尿病药物组合物的制备方法 |
| US12303604B1 (en) | 2024-10-16 | 2025-05-20 | Currax Pharmaceuticals Llc | Pharmaceutical formulations comprising naltrexone and/or bupropion |
Family Cites Families (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3247066A (en) | 1962-09-12 | 1966-04-19 | Parke Davis & Co | Controlled release dosage form containing water-swellable beadlet |
| DE2021147A1 (de) * | 1970-04-30 | 1971-11-11 | Christian Brunnengraeber Chem | Kapsel mit einer Fuellung von Pharmazeutika |
| DE2347531A1 (de) * | 1973-09-21 | 1975-04-30 | Hoechst Ag | Arzneizubereitungen zur oralen diabetes-behandlung |
| US4252786A (en) * | 1979-11-16 | 1981-02-24 | E. R. Squibb & Sons, Inc. | Controlled release tablet |
| ZA822995B (en) * | 1981-05-21 | 1983-12-28 | Wyeth John & Brother Ltd | Slow release pharmaceutical composition |
| US4681583A (en) | 1982-12-20 | 1987-07-21 | Alza Corporation | System for dispersing drug in biological environment |
| JPS60241871A (ja) * | 1984-05-16 | 1985-11-30 | Ajinomoto Co Inc | アスパルテ−ム含有崩壊錠剤の製造法 |
| GB8518301D0 (en) | 1985-07-19 | 1985-08-29 | Fujisawa Pharmaceutical Co | Hydrodynamically explosive systems |
| CH668187A5 (de) * | 1986-08-07 | 1988-12-15 | Ciba Geigy Ag | Therapeutisches system mit systemischer wirkung. |
| DE3629994A1 (de) | 1986-09-03 | 1988-03-17 | Weissenbacher Ernst Rainer Pro | Vorrichtung zur medikamentenapplikation in koerperhoehlen bzw. auf koerperoberflaechen |
| US4874388A (en) * | 1987-06-25 | 1989-10-17 | Alza Corporation | Multi-layer delivery system |
| US4976967A (en) * | 1987-08-03 | 1990-12-11 | Merck & Co., Inc. | Resin modulated drug delivery device for the delivery of HMG-CoA reductase inhibitor salts |
| US4891223A (en) * | 1987-09-03 | 1990-01-02 | Air Products And Chemicals, Inc. | Controlled release delivery coating formulation for bioactive substances |
| US4990535A (en) | 1989-05-03 | 1991-02-05 | Schering Corporation | Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine |
| GB8913889D0 (en) * | 1989-06-16 | 1989-08-02 | May & Baker Ltd | New compositions of matter |
| EP0408496A3 (en) | 1989-07-12 | 1992-07-01 | Ciba-Geigy Ag | Solid dosage form for pharmaceutical substances |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5229131A (en) | 1990-02-05 | 1993-07-20 | University Of Michigan | Pulsatile drug delivery system |
| US5474784A (en) * | 1990-03-02 | 1995-12-12 | British Technology Group Limited | Dispensing device |
| US5226902A (en) * | 1991-07-30 | 1993-07-13 | University Of Utah | Pulsatile drug delivery device using stimuli sensitive hydrogel |
| PT100944B (pt) * | 1991-10-10 | 2000-02-29 | Alza Corp | Dispositivo para o fornecimento osmotico de farmacos com paredes de materiais hidrofobicos |
| US5162117A (en) * | 1991-11-22 | 1992-11-10 | Schering Corporation | Controlled release flutamide composition |
| RU2127586C1 (ru) | 1991-12-27 | 1999-03-20 | Мерк Энд Ко., Инк. | Устройство доставки лекарственного препарата, способ получения устройства |
| US5209746A (en) * | 1992-02-18 | 1993-05-11 | Alza Corporation | Osmotically driven delivery devices with pulsatile effect |
| US5260069A (en) | 1992-11-27 | 1993-11-09 | Anda Sr Pharmaceuticals Inc. | Pulsatile particles drug delivery system |
| US5358941A (en) * | 1992-12-02 | 1994-10-25 | Merck & Co., Inc. | Dry mix formulation for bisphosphonic acids with lactose |
| TW438587B (en) | 1995-06-20 | 2001-06-07 | Takeda Chemical Industries Ltd | A pharmaceutical composition for prophylaxis and treatment of diabetes |
| IT1276130B1 (it) | 1995-11-14 | 1997-10-27 | Gentili Ist Spa | Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo |
| US6011049A (en) | 1997-02-19 | 2000-01-04 | Warner-Lambert Company | Combinations for diabetes |
| US6153632A (en) | 1997-02-24 | 2000-11-28 | Rieveley; Robert B. | Method and composition for the treatment of diabetes |
| DE19718012C1 (de) * | 1997-04-29 | 1998-10-08 | Jenapharm Gmbh | Verfahren zur Herstellung peroral anwendbarer fester Arzneiformen mit gesteuerter Wirkstoffabgabe |
| US5840329A (en) * | 1997-05-15 | 1998-11-24 | Bioadvances Llc | Pulsatile drug delivery system |
| US6004582A (en) * | 1997-05-30 | 1999-12-21 | Laboratorios Phoenix U.S.A, Inc. | Multi-layered osmotic device |
| ES2159184T3 (es) | 1997-06-13 | 2001-09-16 | Novo Nordisk As | Nueva posologia para la dmni. |
| EP1671637A3 (de) | 1997-06-18 | 2007-12-19 | SmithKline Beecham P.L.C. | Behandlung der Diabetes mit Thiazolidindione und Sulphonylurea |
| TR199903057T2 (xx) | 1997-06-18 | 2000-04-21 | Smithkline Beecham Plc | Diabetin tiazolidinedion ve metformin ile tedavisi. |
| GB9715298D0 (en) | 1997-07-18 | 1997-09-24 | Smithkline Beecham Plc | Novel method of treatment |
| GB9715306D0 (en) | 1997-07-18 | 1997-09-24 | Smithkline Beecham Plc | Novel method of treatment |
| GB9715295D0 (en) | 1997-07-18 | 1997-09-24 | Smithkline Beecham Plc | Novel method of treatment |
| DE69814122T2 (de) | 1997-10-09 | 2004-03-18 | Dexcel Pharma Technologies Ltd. | Darreichungsform zur verzögerten, vollständigen wirkstoffabgabe im verdauungstrakt |
| US6056977A (en) * | 1997-10-15 | 2000-05-02 | Edward Mendell Co., Inc. | Once-a-day controlled release sulfonylurea formulation |
| CA2312990C (en) | 1997-12-08 | 2008-04-29 | Bristol-Myers Squibb Company | Novel salts of metformin and method |
| WO1999047128A1 (en) * | 1998-03-19 | 1999-09-23 | Bristol-Myers Squibb Company | Biphasic controlled release delivery system for high solubility pharmaceuticals and method |
| DE69818444T2 (de) * | 1998-07-15 | 2004-05-06 | Merck Santé | Tabletten enthaltend eine Kombination von Glibenclamid und Metformin |
| US6099862A (en) | 1998-08-31 | 2000-08-08 | Andrx Corporation | Oral dosage form for the controlled release of a biguanide and sulfonylurea |
| WO2000025757A1 (en) | 1998-10-29 | 2000-05-11 | Merck & Co., Inc. | Sustained release delivery of highly water-soluble compounds |
| US6096341A (en) * | 1998-10-30 | 2000-08-01 | Pharma Pass Llc | Delayed release tablet of bupropion hydrochloride |
| WO2000028989A1 (en) * | 1998-11-12 | 2000-05-25 | Smithkline Beecham P.L.C. | Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent |
| DE19860698A1 (de) * | 1998-12-30 | 2000-07-06 | Hexal Ag | Neue pharmazeutische Zusammensetzung |
| WO2000059481A1 (en) * | 1999-04-06 | 2000-10-12 | Pharmaquest Ltd. | PHARMACEUTICAL DOSAGE FORM FOR PULSATILE DELIVERY OF d-threo-METHYLPHENIDATE AND A SECOND CNS STIMULANT |
| US6632451B2 (en) * | 1999-06-04 | 2003-10-14 | Dexcel Pharma Technologies Ltd. | Delayed total release two pulse gastrointestinal drug delivery system |
| JP2003504415A (ja) * | 1999-07-20 | 2003-02-04 | メルク エンド カムパニー インコーポレーテッド | 持続放出性薬物分散剤輸送装置 |
| US6787531B1 (en) * | 1999-08-31 | 2004-09-07 | Schering Ag | Pharmaceutical composition for use as a contraceptive |
| EP1095650A1 (de) | 1999-10-29 | 2001-05-02 | Universiteit Leiden | Zweiphasensystem mit kontrollierter Freigabe |
| US6352721B1 (en) * | 2000-01-14 | 2002-03-05 | Osmotica Corp. | Combined diffusion/osmotic pumping drug delivery system |
| US6491949B2 (en) * | 2000-01-14 | 2002-12-10 | Osmotica Corp. | Osmotic device within an osmotic device |
| AR026148A1 (es) * | 2000-01-21 | 2003-01-29 | Osmotica Argentina S A | Dispositivo osmotico con pasaje preformado que aumenta de tamano |
| US6376682B1 (en) * | 2000-02-01 | 2002-04-23 | Takama System, Ltd. | Compound with α-glucosidase inhibiting action and method for producing the same |
| MXPA02007254A (es) * | 2000-02-04 | 2002-12-09 | Depomed Inc | Forma de dosis de cubierta-y-nucleo que se aproxima a liberacion de droga de orden cero. |
| US6627223B2 (en) | 2000-02-11 | 2003-09-30 | Eurand Pharmaceuticals Ltd. | Timed pulsatile drug delivery systems |
| US20030086972A1 (en) | 2000-08-09 | 2003-05-08 | Appel Leah E. | Hydrogel-driven drug dosage form |
| GB0025208D0 (en) * | 2000-10-13 | 2000-11-29 | Euro Celtique Sa | Delayed release pharmaceutical formulations |
| US20040156900A1 (en) * | 2001-04-10 | 2004-08-12 | Shanghvi Dilip Shantilal | Time pulsed release composition |
| FR2825023B1 (fr) * | 2001-05-23 | 2005-04-15 | Flamel Tech Sa | Forme pharmaceutique orale antidiabetique "une prise par jour"comprenant une biguanide et au moins un autre principe actif |
| ITFI20010230A1 (it) * | 2001-11-29 | 2003-05-29 | Menarini Int Operations Lu Sa | Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii |
| WO2004108067A2 (en) * | 2003-04-03 | 2004-12-16 | Sun Pharmaceutical Industries Limited | Programmed drug delivery system |
-
2002
- 2002-01-11 US US10/466,036 patent/US7964216B2/en not_active Expired - Fee Related
- 2002-01-11 CA CA2434169A patent/CA2434169C/en not_active Expired - Fee Related
- 2002-01-11 BR BRPI0206432A patent/BRPI0206432A2/pt not_active IP Right Cessation
- 2002-01-11 AT AT06019650T patent/ATE508738T1/de not_active IP Right Cessation
- 2002-01-11 EP EP06019650A patent/EP1738751B1/de not_active Expired - Lifetime
- 2002-01-11 MX MXPA03006217A patent/MXPA03006217A/es active IP Right Grant
- 2002-01-11 PL PL02362687A patent/PL362687A1/xx not_active Application Discontinuation
- 2002-01-11 CA CA2725833A patent/CA2725833A1/en not_active Abandoned
- 2002-01-11 WO PCT/IN2002/000005 patent/WO2002055009A1/en not_active Ceased
- 2002-01-11 JP JP2002555746A patent/JP4633329B2/ja not_active Expired - Fee Related
- 2002-01-11 EP EP02710296A patent/EP1349531A1/de not_active Withdrawn
-
2011
- 2011-06-17 US US13/163,168 patent/US20110250271A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1738751A3 (de) | 2007-01-17 |
| US20110250271A1 (en) | 2011-10-13 |
| CA2725833A1 (en) | 2002-07-18 |
| CA2434169A1 (en) | 2002-07-18 |
| EP1349531A1 (de) | 2003-10-08 |
| US7964216B2 (en) | 2011-06-21 |
| JP2004523510A (ja) | 2004-08-05 |
| MXPA03006217A (es) | 2004-10-15 |
| US20040086562A1 (en) | 2004-05-06 |
| WO2002055009A1 (en) | 2002-07-18 |
| CA2434169C (en) | 2011-03-15 |
| PL362687A1 (en) | 2004-11-02 |
| EP1738751B1 (de) | 2011-05-11 |
| BRPI0206432A2 (pt) | 2016-10-25 |
| EP1738751A2 (de) | 2007-01-03 |
| JP4633329B2 (ja) | 2011-02-16 |
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| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |