ATE513855T1 - Antikörper gegen il-13-rezeptor-alpha-1 und verwendungen dafür - Google Patents

Antikörper gegen il-13-rezeptor-alpha-1 und verwendungen dafür

Info

Publication number
ATE513855T1
ATE513855T1 AT06706157T AT06706157T ATE513855T1 AT E513855 T1 ATE513855 T1 AT E513855T1 AT 06706157 T AT06706157 T AT 06706157T AT 06706157 T AT06706157 T AT 06706157T AT E513855 T1 ATE513855 T1 AT E513855T1
Authority
AT
Austria
Prior art keywords
antibodies
receptor alpha
receptor
alpha
Prior art date
Application number
AT06706157T
Other languages
English (en)
Inventor
Josef Endl
Maria Fuentes
Yvo Graus
Adelbert Grossmann
Sebastian Neumann
Paul Parren
Frank Rebers
Joerg Regula
Ralf Schumacher
Stefan Seeber
Jan Stracke
Kay-Gunnar Stubenrauch
De Winkel Jan Van
Vugt Martine Van
Sandra Vereecken-Verploegen
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE513855T1 publication Critical patent/ATE513855T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT06706157T 2005-01-03 2006-01-02 Antikörper gegen il-13-rezeptor-alpha-1 und verwendungen dafür ATE513855T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05000003 2005-01-03
EP05002229 2005-02-03
PCT/EP2006/000005 WO2006072564A1 (en) 2005-01-03 2006-01-02 Antibodies against il-13 receptor alpha 1 and uses thereof

Publications (1)

Publication Number Publication Date
ATE513855T1 true ATE513855T1 (de) 2011-07-15

Family

ID=36199730

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06706157T ATE513855T1 (de) 2005-01-03 2006-01-02 Antikörper gegen il-13-rezeptor-alpha-1 und verwendungen dafür

Country Status (19)

Country Link
US (2) US7807158B2 (de)
EP (1) EP1836226B1 (de)
JP (1) JP5086098B2 (de)
KR (1) KR100934894B1 (de)
AR (1) AR051888A1 (de)
AT (1) ATE513855T1 (de)
AU (1) AU2006204480B2 (de)
BR (1) BRPI0606368A2 (de)
CA (1) CA2592614C (de)
CR (1) CR9209A (de)
IL (1) IL184205A0 (de)
MA (1) MA29226B1 (de)
MX (1) MX2007008128A (de)
NO (1) NO20073655L (de)
NZ (1) NZ556126A (de)
RU (1) RU2413736C2 (de)
SG (1) SG172504A1 (de)
TW (2) TW200902555A (de)
WO (1) WO2006072564A1 (de)

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PT2483305T (pt) 2009-10-01 2016-11-04 Hoffmann La Roche Filtração final de imunoglobulina em várias etapas
CN105624118B (zh) 2009-10-19 2019-08-13 弗·哈夫曼-拉罗切有限公司 非交叉反应性抗IgG抗体
BR112012012873B1 (pt) 2009-12-22 2021-08-31 F.Hoffmann-La Roche Ag Método para fornecer uma sequência de ácido nucleico que codifica uma imunoglobulina e método para produzir uma imunoglobulina
WO2012022682A1 (en) 2010-08-17 2012-02-23 F. Hoffmann-La Roche Ag Anti-human igg1 antibody
JP6073811B2 (ja) 2011-02-02 2017-02-01 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft クロマトグラフィーカラムサポート
WO2012145746A1 (en) * 2011-04-21 2012-10-26 The Regents Of The University Of Colorado, A Body Corporate Compositions and methods for the treatment of neuromyelitis optica
IL312711A (en) 2012-08-21 2024-07-01 Regeneron Pharma Methods for the treatment or prevention of asthma through the administration of an antagonist to 4R-IL
KR102576903B1 (ko) 2012-09-07 2023-09-13 리제너론 파아마슈티컬스, 인크. Il-4r 길항제 투여로 아토피성 피부염을 치료하는 방법
TWI755763B (zh) 2013-06-04 2022-02-21 美商再生元醫藥公司 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法
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EP4124624A3 (de) 2013-12-20 2023-05-03 Intervet International B.V. Antikörper gegen hunde-pd-1
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ES2877532T3 (es) 2015-08-21 2021-11-17 Hoffmann La Roche Procedimiento para la reducción de proteínas de célula huésped en cromatografía de afinidad
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Also Published As

Publication number Publication date
TW200902555A (en) 2009-01-16
AR051888A1 (es) 2007-02-14
KR100934894B1 (ko) 2010-01-07
CA2592614C (en) 2015-04-14
KR20070091180A (ko) 2007-09-07
HK1112006A1 (en) 2008-08-22
TWI306862B (en) 2009-03-01
BRPI0606368A2 (pt) 2009-06-23
JP2008526187A (ja) 2008-07-24
NO20073655L (no) 2007-08-02
MX2007008128A (es) 2007-07-20
CA2592614A1 (en) 2006-07-13
US20110086026A1 (en) 2011-04-14
CR9209A (es) 2007-08-28
US20060263356A1 (en) 2006-11-23
JP5086098B2 (ja) 2012-11-28
RU2413736C2 (ru) 2011-03-10
EP1836226A1 (de) 2007-09-26
WO2006072564A1 (en) 2006-07-13
IL184205A0 (en) 2007-10-31
NZ556126A (en) 2008-09-26
EP1836226B1 (de) 2011-06-22
TW200635945A (en) 2006-10-16
RU2007129676A (ru) 2009-02-10
MA29226B1 (fr) 2008-02-01
AU2006204480A1 (en) 2006-07-13
AU2006204480B2 (en) 2011-06-09
SG172504A1 (en) 2011-07-28
US7807158B2 (en) 2010-10-05

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