BRPI0606368A2 - anticorpos contra receptor alfa1 de il-13, usos dos mesmos, composição farmacêitica, e método para fabricação da mesma, célula hospedeira recombinante, ácido nucléico, vetor de expressão, método para a produção de um polipeptìdeo , bem como linhagem celular de hibridoma - Google Patents
anticorpos contra receptor alfa1 de il-13, usos dos mesmos, composição farmacêitica, e método para fabricação da mesma, célula hospedeira recombinante, ácido nucléico, vetor de expressão, método para a produção de um polipeptìdeo , bem como linhagem celular de hibridomaInfo
- Publication number
- BRPI0606368A2 BRPI0606368A2 BRPI0606368-3A BRPI0606368A BRPI0606368A2 BR PI0606368 A2 BRPI0606368 A2 BR PI0606368A2 BR PI0606368 A BRPI0606368 A BR PI0606368A BR PI0606368 A2 BRPI0606368 A2 BR PI0606368A2
- Authority
- BR
- Brazil
- Prior art keywords
- nucleic acid
- pharmaceutical composition
- antibodies against
- host cell
- polypeptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
ANTICORPOS CONTRA RECEPTOR ALFA1 DE IL-13, USOS DOS MESMOS, COMPOSIçãO FARMACêUTICA, E MéTODO PARA FABRICAçãO DA MESMA, CéLULA HOSPEDEIRA RECOMBINANTE, áCIDO NUCLéICO, VETOR DE EXPRESSãO, MéTODO PARA A PRODUçãO DE UM POLIPEPTIDEO, BEM COMO LINHAGEM CELULAR DE HIBRIDOMA. A presente invenção refere-se a um anticorpo que se liga a IL-l3Ral, inibe a bioatividade de IL-13 e compreende uma cadeia pesada variável e leve variável, caracterizado pelo fato de que a seqúência de aminoácido de cadeia pesada variável CDR3 do dito anticorpo é selecionada a partir do grupo que consiste nas seqúências de CDR3 de cadeia pesada de SEQ ID NO: 1, 3, 5, 7 ou 9 é útil no tratamento de asma e doenças alérgicas.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05000003 | 2005-01-03 | ||
| EP05002229 | 2005-02-03 | ||
| PCT/EP2006/000005 WO2006072564A1 (en) | 2005-01-03 | 2006-01-02 | Antibodies against il-13 receptor alpha 1 and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0606368A2 true BRPI0606368A2 (pt) | 2009-06-23 |
Family
ID=36199730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0606368-3A BRPI0606368A2 (pt) | 2005-01-03 | 2006-01-02 | anticorpos contra receptor alfa1 de il-13, usos dos mesmos, composição farmacêitica, e método para fabricação da mesma, célula hospedeira recombinante, ácido nucléico, vetor de expressão, método para a produção de um polipeptìdeo , bem como linhagem celular de hibridoma |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US7807158B2 (pt) |
| EP (1) | EP1836226B1 (pt) |
| JP (1) | JP5086098B2 (pt) |
| KR (1) | KR100934894B1 (pt) |
| AR (1) | AR051888A1 (pt) |
| AT (1) | ATE513855T1 (pt) |
| AU (1) | AU2006204480B2 (pt) |
| BR (1) | BRPI0606368A2 (pt) |
| CA (1) | CA2592614C (pt) |
| CR (1) | CR9209A (pt) |
| IL (1) | IL184205A0 (pt) |
| MA (1) | MA29226B1 (pt) |
| MX (1) | MX2007008128A (pt) |
| NO (1) | NO20073655L (pt) |
| NZ (1) | NZ556126A (pt) |
| RU (1) | RU2413736C2 (pt) |
| SG (1) | SG172504A1 (pt) |
| TW (2) | TWI306862B (pt) |
| WO (1) | WO2006072564A1 (pt) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR045563A1 (es) | 2003-09-10 | 2005-11-02 | Warner Lambert Co | Anticuerpos dirigidos a m-csf |
| CA2664343C (en) | 2006-10-02 | 2016-04-26 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human il-4 receptor |
| US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| PL2068922T3 (pl) | 2006-10-19 | 2012-11-30 | Csl Ltd | Przeciwciała anty-IL-13R alfa1 i ich zastosowania |
| EP2076285A4 (en) * | 2006-10-19 | 2010-06-30 | Merck Sharp & Dohme | ANTIBODY ANTAGONISTS OF INTERLEUKIN 13 RECEPTOR 1 |
| ES2501947T3 (es) | 2006-10-19 | 2014-10-02 | Csl Limited | Antagonistas de anticuerpos de alta afinidad del receptor alfa 1 de interleucina |
| RU2009148891A (ru) | 2007-06-01 | 2011-07-20 | Ф.Хоффманн-Ля Рош Аг (Ch) | Очистка иммуноглобулина |
| JP2010531340A (ja) * | 2007-07-10 | 2010-09-24 | エフ．ホフマン−ラ ロシュ アーゲー | 新規処方物 |
| PT2592148T (pt) * | 2007-10-12 | 2018-11-12 | Hoffmann La Roche | Expressão proteica de múltiplos ácidos nucleicos |
| EP2050764A1 (en) * | 2007-10-15 | 2009-04-22 | sanofi-aventis | Novel polyvalent bispecific antibody format and uses thereof |
| AU2008337904B2 (en) | 2007-12-15 | 2014-02-13 | F. Hoffmann-La Roche Ag | Distinguishing assay |
| ES2549769T3 (es) * | 2009-03-25 | 2015-11-02 | Genentech, Inc. | Anticuerpos anti-FGFR3 y métodos que emplean los mismos |
| US8530392B2 (en) * | 2009-05-13 | 2013-09-10 | Shionogi & Co., Ltd. | Test agent for visceral obesity and use thereof |
| BR112012001843A2 (pt) | 2009-07-30 | 2016-03-15 | Hoffmann La Roche | separador de coluna de cromatografia móvel |
| WO2011038894A1 (en) | 2009-10-01 | 2011-04-07 | F. Hoffmann-La Roche Ag | Protein a chromatography |
| KR101653471B1 (ko) | 2009-10-01 | 2016-09-01 | 에프. 호프만-라 로슈 아게 | 다단계 최종 여과 |
| WO2011048043A1 (en) | 2009-10-19 | 2011-04-28 | F. Hoffmann-La Roche Ag | NON-CROSS-REACTIVE ANTI IgG ANTIBODIES |
| EP2516460B1 (en) | 2009-12-22 | 2015-03-04 | F.Hoffmann-La Roche Ag | Sequence dependent aggregation |
| EP2606071B1 (en) | 2010-08-17 | 2019-12-18 | F.Hoffmann-La Roche Ag | Anti-human igg1 antibody |
| WO2012104278A1 (en) | 2011-02-02 | 2012-08-09 | F. Hoffmann-La Roche Ag | Chromatography column support |
| EP2699256B1 (en) * | 2011-04-21 | 2017-09-27 | The Regents of the University of Colorado, a body corporate | Compositions and methods for the treatment of neuromyelitis optica |
| KR102502640B1 (ko) | 2012-08-21 | 2023-02-23 | 사노피 바이오테크놀로지 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
| CN118286417A (zh) | 2012-09-07 | 2024-07-05 | 瑞泽恩制药公司 | 以il-4r拮抗剂治疗特应性皮炎的方法 |
| TWI755763B (zh) | 2013-06-04 | 2022-02-21 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
| RS59354B1 (sr) | 2013-06-21 | 2019-10-31 | Sanofi Biotechnology | Postupci lečenja nosne polipoze davanjem il-4r antagonista |
| JP6563910B2 (ja) | 2013-07-04 | 2019-08-21 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 血清サンプル中の抗薬物抗体を検出するための干渉抑制イムノアッセイ |
| TWI634900B (zh) | 2013-07-11 | 2018-09-11 | 再生元醫藥公司 | 藉由投與ｉｌ－４ｒ抑制劑治療嗜酸性食道炎的方法 |
| US8980273B1 (en) | 2014-07-15 | 2015-03-17 | Kymab Limited | Method of treating atopic dermatitis or asthma using antibody to IL4RA |
| US8986691B1 (en) | 2014-07-15 | 2015-03-24 | Kymab Limited | Method of treating atopic dermatitis or asthma using antibody to IL4RA |
| AU2014368453B2 (en) | 2013-12-20 | 2020-04-16 | Intervet International B.V. | Caninized murine anti-canine PD-1 antibodies |
| IL315136A (en) | 2014-02-21 | 2024-10-01 | Sanofi Biotechnology | Methods for treating or preventing asthma by administering an il-4rantagonist |
| PT3110848T (pt) | 2014-09-24 | 2024-03-05 | Regeneron Pharma | Métodos para tratamento de infeção cutânea por administração de um antagonista do il-4r |
| ES2853823T3 (es) | 2014-09-30 | 2021-09-17 | Intervet Int Bv | Anticuerpos de PD-L1 que se unen a PD-L1 canino |
| CA3246946A1 (en) | 2014-11-14 | 2025-11-29 | Sanofi Biotechnology | Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist |
| MX388197B (es) | 2015-08-21 | 2025-03-19 | Hoffmann La Roche | Método para la reducción de proteínas de células hospederas en cromatografía de afinidad. |
| HRP20211737T1 (hr) * | 2015-08-21 | 2022-02-18 | F. Hoffmann - La Roche Ag | Postupak za smanjenje proteina stanice domaćina u afinitetnoj kromatografiji |
| US11091556B2 (en) | 2015-12-18 | 2021-08-17 | Intervet Inc. | Caninized human antibodies to human IL-4R alpha |
| ES3014160T3 (en) | 2015-12-18 | 2025-04-21 | Intervet Int Bv | Caninized human antibodies to human and canine il-4r alpha |
| WO2018011405A1 (en) * | 2016-07-15 | 2018-01-18 | Universität Zürich | Il-13ralpha1 antibodies for use in treatment of atopic inflammation, sepsis and neutropenia |
| KR102872485B1 (ko) | 2016-09-01 | 2025-10-20 | 리제너론 파아마슈티컬스, 인크. | Il-4r 길항제를 투여함에 의해 알레르기를 예방하거나 치료하기 위한 방법 |
| JOP20190009A1 (ar) | 2016-09-21 | 2019-01-27 | Alx Oncology Inc | أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها |
| TWI784988B (zh) | 2016-12-01 | 2022-12-01 | 美商再生元醫藥公司 | 治療發炎症狀的方法 |
| CA3045944A1 (en) | 2016-12-07 | 2018-06-14 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| WO2018183932A1 (en) | 2017-03-30 | 2018-10-04 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with a il-13 inhibitor |
| WO2019028367A1 (en) | 2017-08-04 | 2019-02-07 | Regeneron Pharmaceuticals, Inc. | METHODS OF TREATING ESOPHAGITIS WITH ACTIVE EOSINOPHILES |
| PT3515465T (pt) | 2017-08-18 | 2024-03-04 | Regeneron Pharma | Métodos para o tratamento de uma dermatite atópica grave mediante a administração de um inibidor de il-4r |
| US11034768B2 (en) | 2017-10-30 | 2021-06-15 | Sanofi Biotechnology | Methods for treating or preventing asthma by administering an IL-4R antagonist |
| WO2019183266A1 (en) | 2018-03-21 | 2019-09-26 | ALX Oncology Inc. | Antibodies against signal-regulatory protein alpha and methods of use |
| MX2020012064A (es) | 2018-05-13 | 2021-04-13 | Regeneron Pharma | Metodos para tratar la dermatitis atopica administrando un inhibidor de il-4r. |
| CN113348011B (zh) | 2018-11-19 | 2023-04-18 | 比奥拉治疗股份有限公司 | 用生物治疗剂治疗疾病的方法和装置 |
| KR20210143246A (ko) | 2019-03-21 | 2021-11-26 | 리제너론 파아마슈티컬스, 인크. | 알레르기 치료용 il-4/il-13 경로 억제제 및 형질 세포 절제의 병용 |
| WO2020197502A1 (en) | 2019-03-26 | 2020-10-01 | Aslan Pharmaceuticals Pte Ltd | Treatment employing anti-il-13r antibody or binding fragment thereof |
| KR20220034878A (ko) | 2019-07-16 | 2022-03-18 | 사노피 바이오테크놀로지 | Il-4r 길항제를 투여하여 천식을 치료 또는 예방하는 방법 |
| US11504426B2 (en) | 2019-08-05 | 2022-11-22 | Regeneron Pharmaceuticals, Inc. | Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an IL-4R antagonist |
| JP7736667B2 (ja) | 2019-08-05 | 2025-09-09 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Ｉｌ－４ｒアンタゴニストを投与することによるアトピー性皮膚炎の治療方法 |
| CN121197633A (zh) | 2019-12-13 | 2025-12-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| WO2022186772A1 (en) | 2021-03-01 | 2022-09-09 | Aslan Pharmaceuticals Pte Ltd | TREATMENT OF ATOPIC DERMATITIS EMPLOYING ANTI-IL-13Rα1 ANTIBODY OR BINDING FRAGMENT THEREOF |
| WO2022186773A1 (en) | 2021-03-01 | 2022-09-09 | Aslan Pharmaceuticals Pte Ltd | TREATMENT OF ATOPIC DERMATITIS EMPLOYING ANTI-IL-13Rα1 ANTIBODY OR BINDING FRAGMENT THEREOF IN AN ALLERGIC POPULATION |
| WO2023048650A1 (en) | 2021-09-27 | 2023-03-30 | Aslan Pharmaceuticals Pte Ltd | TREATMENT OF PRURITIS EMPLOYING ANTI-IL13Rα1 ANTIBODY OR BINDING FRAGMENT THEREOF |
| JP2024534717A (ja) | 2021-09-27 | 2024-09-24 | アスラン ファーマシューティカルズ ピーティーイー リミテッド | 中等症から重症のアトピー性皮膚炎の処置のための方法 |
| WO2023075702A1 (en) | 2021-10-29 | 2023-05-04 | Aslan Pharmaceuticals Pte Ltd | Anti-il-13r antibody formulation |
| KR20250075749A (ko) | 2022-08-26 | 2025-05-28 | 아슬란 파마슈티컬스 피티이 엘티디 | 항-il13r 항체의 고농도 제형 |
| CN120077070A (zh) | 2022-09-06 | 2025-05-30 | 亚狮康私人有限公司 | 皮炎患者的睡眠缺失或睡眠障碍的治疗 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5614191A (en) | 1995-03-15 | 1997-03-25 | The United States Of America As Represented By The Department Of Health And Human Services | IL-13 receptor specific chimeric proteins and uses thereof |
| ES2334408T3 (es) | 1995-10-23 | 2010-03-09 | Zenyth Operations Pty Ltd | Receptor de hematopoyetina y secuencias geneticas que lo codifican. |
| US5843659A (en) * | 1996-03-21 | 1998-12-01 | Apoptosis Technology, Inc. | Apoptosis gene EI24, compositions, and methods of use |
| EP1449851A4 (en) | 2001-11-27 | 2005-11-16 | Mochida Pharm Co Ltd | NEUTRALIZING ANTIBODIES OF IL13 ALPHA RECEPTOR 1 |
| AR037756A1 (es) * | 2001-12-17 | 2004-12-01 | Bayer Corp | Anticuerpo que inhibe la actividad del factor de las celulas precursoras y su uso para el tratamiento del asma. |
| CA2480059C (en) | 2002-03-22 | 2015-11-24 | Amrad Operations Pty. Ltd. | Monoclonal antibody against interleukin-13 receptor alpha 1 (il-13r.alpha.1) |
| WO2004081186A2 (en) * | 2003-03-10 | 2004-09-23 | Applera Corporation | Single nucleotide polymorphisms associated with stenosis, methods of detection and uses thereof |
| UA97086C2 (uk) * | 2003-07-15 | 2012-01-10 | Емджен, Інк. | Виділене людське антитіло, яке специфічно зв'язується з фактором росту нервової тканини (ngf) |
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2005
- 2005-12-30 TW TW094147847A patent/TWI306862B/zh not_active IP Right Cessation
- 2005-12-30 TW TW097137970A patent/TW200902555A/zh unknown
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2006
- 2006-01-02 WO PCT/EP2006/000005 patent/WO2006072564A1/en not_active Ceased
- 2006-01-02 KR KR1020077015296A patent/KR100934894B1/ko not_active Expired - Fee Related
- 2006-01-02 NZ NZ556126A patent/NZ556126A/en not_active IP Right Cessation
- 2006-01-02 CA CA2592614A patent/CA2592614C/en not_active Expired - Fee Related
- 2006-01-02 SG SG2009087206A patent/SG172504A1/en unknown
- 2006-01-02 AT AT06706157T patent/ATE513855T1/de not_active IP Right Cessation
- 2006-01-02 BR BRPI0606368-3A patent/BRPI0606368A2/pt not_active IP Right Cessation
- 2006-01-02 MX MX2007008128A patent/MX2007008128A/es active IP Right Grant
- 2006-01-02 RU RU2007129676/10A patent/RU2413736C2/ru not_active IP Right Cessation
- 2006-01-02 EP EP06706157A patent/EP1836226B1/en not_active Expired - Lifetime
- 2006-01-02 JP JP2007548835A patent/JP5086098B2/ja not_active Expired - Fee Related
- 2006-01-02 AU AU2006204480A patent/AU2006204480B2/en not_active Expired - Fee Related
- 2006-01-03 US US11/325,197 patent/US7807158B2/en not_active Expired - Fee Related
- 2006-01-03 AR ARP060100010A patent/AR051888A1/es unknown
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2007
- 2007-06-25 IL IL184205A patent/IL184205A0/en unknown
- 2007-06-26 CR CR9209A patent/CR9209A/es not_active Application Discontinuation
- 2007-07-06 MA MA30048A patent/MA29226B1/fr unknown
- 2007-07-17 NO NO20073655A patent/NO20073655L/no not_active Application Discontinuation
-
2010
- 2010-07-26 US US12/843,225 patent/US20110086026A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20070091180A (ko) | 2007-09-07 |
| MX2007008128A (es) | 2007-07-20 |
| TW200902555A (en) | 2009-01-16 |
| MA29226B1 (fr) | 2008-02-01 |
| RU2007129676A (ru) | 2009-02-10 |
| CA2592614C (en) | 2015-04-14 |
| AU2006204480A1 (en) | 2006-07-13 |
| EP1836226B1 (en) | 2011-06-22 |
| ATE513855T1 (de) | 2011-07-15 |
| TWI306862B (en) | 2009-03-01 |
| EP1836226A1 (en) | 2007-09-26 |
| TW200635945A (en) | 2006-10-16 |
| RU2413736C2 (ru) | 2011-03-10 |
| US20060263356A1 (en) | 2006-11-23 |
| NZ556126A (en) | 2008-09-26 |
| SG172504A1 (en) | 2011-07-28 |
| KR100934894B1 (ko) | 2010-01-07 |
| WO2006072564A1 (en) | 2006-07-13 |
| NO20073655L (no) | 2007-08-02 |
| JP5086098B2 (ja) | 2012-11-28 |
| IL184205A0 (en) | 2007-10-31 |
| AU2006204480B2 (en) | 2011-06-09 |
| AR051888A1 (es) | 2007-02-14 |
| US7807158B2 (en) | 2010-10-05 |
| US20110086026A1 (en) | 2011-04-14 |
| CR9209A (es) | 2007-08-28 |
| HK1112006A1 (en) | 2008-08-22 |
| CA2592614A1 (en) | 2006-07-13 |
| JP2008526187A (ja) | 2008-07-24 |
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