ATE5141T1 - Xanthon- und thioxanthonderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen. - Google Patents

Xanthon- und thioxanthonderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
ATE5141T1
ATE5141T1 AT79300778T AT79300778T ATE5141T1 AT E5141 T1 ATE5141 T1 AT E5141T1 AT 79300778 T AT79300778 T AT 79300778T AT 79300778 T AT79300778 T AT 79300778T AT E5141 T1 ATE5141 T1 AT E5141T1
Authority
AT
Austria
Prior art keywords
group
groups
effects
formula
carbon atoms
Prior art date
Application number
AT79300778T
Other languages
English (en)
Inventor
Niels Lassen
Klaus Peter Bogeso
Peter Bregnedal Hansen
Jorn Lasse Martin Buus
Allan Johan Bigler
Original Assignee
Kefalas A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kefalas A/S filed Critical Kefalas A/S
Application granted granted Critical
Publication of ATE5141T1 publication Critical patent/ATE5141T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/10—Dibenzothiopyrans; Hydrogenated dibenzothiopyrans
    • C07D335/12—Thioxanthenes
    • C07D335/14—Thioxanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
    • C07D335/18—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polymerisation Methods In General (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT79300778T 1978-05-12 1979-05-04 Xanthon- und thioxanthonderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen. ATE5141T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1931078 1978-05-12
EP79300778A EP0005607B1 (de) 1978-05-12 1979-05-04 Xanthon- und Thioxanthonderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE5141T1 true ATE5141T1 (de) 1983-11-15

Family

ID=10127259

Family Applications (1)

Application Number Title Priority Date Filing Date
AT79300778T ATE5141T1 (de) 1978-05-12 1979-05-04 Xanthon- und thioxanthonderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.

Country Status (14)

Country Link
US (3) US4285956A (de)
EP (1) EP0005607B1 (de)
JP (1) JPS54154772A (de)
AT (1) ATE5141T1 (de)
AU (1) AU522926B2 (de)
CA (1) CA1127648A (de)
DE (1) DE2966344D1 (de)
DK (1) DK190179A (de)
ES (1) ES480468A1 (de)
FI (1) FI791503A7 (de)
IE (1) IE48261B1 (de)
NO (1) NO150837C (de)
NZ (1) NZ190373A (de)
ZA (1) ZA792250B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4356184A (en) * 1980-06-04 1982-10-26 G. D. Searle & Co. Anti-allergic or antihypertensive 1-piperidinylmethyl benzenamines
US4501749A (en) * 1983-10-31 1985-02-26 Merck & Co., Inc. Peripherally selective dopamine antagonists in the treatment of ocular hypertension
US4777177A (en) * 1984-10-19 1988-10-11 Ciba-Geigy Corporation Pesticidal thioxanthen-9-ylidenepiperidines
US5393890A (en) * 1988-06-02 1995-02-28 Ajinomoto Co., Inc. Piperidine derivatives and hypotensives containing the same
US5250681A (en) * 1988-06-02 1993-10-05 Ajinomoto Co., Inc. Piperidine derivatives and hypotensives containing the same
CA2004211A1 (en) * 1988-11-30 1990-05-31 Masataka Syoji Piperidine derivatives and hyportensives containing the same
EP1306376A1 (de) * 2001-10-25 2003-05-02 Biofrontera Pharmaceuticals AG Derivaten von 4-(Thio- oder Selenoxanthen-9-yliden)-Piperidin oder Acridine und ihre Verwendung als selektieven 5-HT2B antagonisten
US7060711B2 (en) * 2001-10-25 2006-06-13 Biofrontera Bioscience Gmbh Derivatives of 4-(thio- or selenoxanthene-9-ylidene)-piperidine or acridine and its use as a selective 5-HT2B receptor antagonist
NZ572901A (en) * 2003-06-27 2010-06-25 Janssen Pharmaceutica Nv Tricyclic delta opioid modulators
US7553850B2 (en) * 2004-08-05 2009-06-30 Janssen Pharmaceutica Nv Tricyclic-bridged piperidinylidene derivatives as δ-opioid modulators
WO2006069277A1 (en) 2004-12-22 2006-06-29 Janssen Pharmaceutica N.V. TRICYCLIC δ-OPIOID MODULATORS
CA2592462A1 (en) * 2004-12-22 2006-06-29 Janssen Pharmaceutica N.V. Tricyclic delta-opioid modulators
EP1833826B1 (de) 2004-12-22 2009-05-27 Janssen Pharmaceutica N.V. Tricyclische delta-opioid-modulatoren
KR20070104380A (ko) * 2005-01-06 2007-10-25 얀센 파마슈티카 엔.브이. 트리사이클릭 δ-오피오이드 조절제
RU2008101667A (ru) * 2005-06-16 2009-07-27 Янссен Фармацевтика Н.В. (Be) Трициклические модуляторы опиоидов

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470188A (en) * 1967-01-05 1969-09-30 Smithkline Corp 9-cycloalkyl-lower alkyl-piperidylidene derivatives of xanthenes and thioxanthenes
US3974285A (en) * 1974-04-10 1976-08-10 Merck & Co., Inc. 10,11-Furo-derivatives of cyproheptadine
US4086350A (en) * 1974-11-06 1978-04-25 Smithkline Corporation Pharmaceutical compositions and method of producing anti-psychotic activity without extrapyramidal symptoms
US4031222A (en) * 1975-12-22 1977-06-21 Merck & Co., Inc. Trifluoromethylthio (and sulfonyl) derivatives of cyproheptadine analogs
US4073912A (en) * 1976-10-12 1978-02-14 Smithkline Corporation Piperidylidene derivatives of benzo-fused xanthenes, thioxanthenes and dibenzoxepins and antipsychotic use thereof

Also Published As

Publication number Publication date
ZA792250B (en) 1980-08-27
US4285956A (en) 1981-08-25
US4309429A (en) 1982-01-05
IE48261B1 (en) 1984-11-14
US4275209A (en) 1981-06-23
EP0005607B1 (de) 1983-10-26
NZ190373A (en) 1981-12-15
DK190179A (da) 1979-11-13
CA1127648A (en) 1982-07-13
FI791503A7 (fi) 1981-01-01
EP0005607A1 (de) 1979-11-28
ES480468A1 (es) 1980-07-01
AU522926B2 (en) 1982-07-01
JPS54154772A (en) 1979-12-06
NO150837B (no) 1984-09-17
NO791592L (no) 1979-11-13
DE2966344D1 (en) 1983-12-01
NO150837C (no) 1985-01-09
IE791105L (en) 1979-11-12
AU4694179A (en) 1979-11-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee