ATE518966T1 - Systeme und verfahren zur bestimmung von übersprechungskoeffizienten in pcr und anderen datensets - Google Patents

Systeme und verfahren zur bestimmung von übersprechungskoeffizienten in pcr und anderen datensets

Info

Publication number
ATE518966T1
ATE518966T1 AT08773727T AT08773727T ATE518966T1 AT E518966 T1 ATE518966 T1 AT E518966T1 AT 08773727 T AT08773727 T AT 08773727T AT 08773727 T AT08773727 T AT 08773727T AT E518966 T1 ATE518966 T1 AT E518966T1
Authority
AT
Austria
Prior art keywords
talk
cross
data sets
coefficients
curves
Prior art date
Application number
AT08773727T
Other languages
English (en)
Inventor
Ronald Kurnik
Aditya Sane
Chris Elkin
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE518966T1 publication Critical patent/ATE518966T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Cable Transmission Systems, Equalization Of Radio And Reduction Of Echo (AREA)
  • Mobile Radio Communication Systems (AREA)
  • Radio Transmission System (AREA)
AT08773727T 2007-06-29 2008-06-27 Systeme und verfahren zur bestimmung von übersprechungskoeffizienten in pcr und anderen datensets ATE518966T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94706507P 2007-06-29 2007-06-29
PCT/EP2008/005255 WO2009003645A1 (en) 2007-06-29 2008-06-27 Systems and methods for determining cross-talk coefficients in pcr and other data sets

Publications (1)

Publication Number Publication Date
ATE518966T1 true ATE518966T1 (de) 2011-08-15

Family

ID=39846613

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08773727T ATE518966T1 (de) 2007-06-29 2008-06-27 Systeme und verfahren zur bestimmung von übersprechungskoeffizienten in pcr und anderen datensets

Country Status (8)

Country Link
US (1) US8095322B2 (de)
EP (1) EP2160594B1 (de)
JP (1) JP5400768B2 (de)
CN (1) CN101688841B (de)
AT (1) ATE518966T1 (de)
CA (1) CA2691907C (de)
ES (1) ES2370678T3 (de)
WO (1) WO2009003645A1 (de)

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US20090181391A1 (en) * 2007-11-01 2009-07-16 Zymo Research Corporation Methods for analysis of dna methylation percentage
CN102046807B (zh) * 2008-04-24 2014-11-26 3M创新有限公司 利用小波变换分析核酸扩增曲线
WO2010085548A2 (en) * 2009-01-22 2010-07-29 Li-Cor, Inc. Single molecule proteomics with dynamic probes
EP3375891B1 (de) * 2009-09-10 2020-02-19 DiaSorin S.p.A. Verfahren und vorrichtungen zur kompensation von spektralem übersprechen bei der multiplex-nukleinsäureamplifikation
KR101969846B1 (ko) 2012-06-28 2019-04-17 삼성전자주식회사 Ｐｃｒ 데이터 및 다른 데이터에서 크로스토크의 영향을 보상하여 핵산을 분석하는 방법 및 장치
JP2015225032A (ja) * 2014-05-29 2015-12-14 株式会社日立ハイテクノロジーズ 核酸増幅分析装置
WO2016127082A1 (en) * 2015-02-06 2016-08-11 Life Technologies Corporation Methods and systems for determining optical regions of interest
WO2017086762A1 (en) * 2015-11-20 2017-05-26 Seegene, Inc. Method for calibrating a data set of a target analyte
US20210317515A1 (en) * 2018-07-10 2021-10-14 Gen-Probe Incorporated Methods and systems for detecting and quantifying nucleic acids
CN109859188B (zh) * 2019-01-31 2021-04-06 领航基因科技（杭州）有限公司 一种基于均值漂移算法的荧光串扰校正方法及其应用
US11188778B1 (en) * 2020-05-05 2021-11-30 Illumina, Inc. Equalization-based image processing and spatial crosstalk attenuator
CN112289389B (zh) * 2020-11-05 2022-08-30 中南大学 一种影响靶向治疗药物疗效的评估模型
CN117795093A (zh) * 2021-06-25 2024-03-29 豪夫迈·罗氏有限公司 具有增加的灵敏度的用于进行温度多重pcr的方法
EP4374343B1 (de) 2021-07-19 2025-12-03 Illumina, Inc. Intensitätsextraktion mit interpolation und anpassung für basisanrufe
CN116399836A (zh) * 2022-11-23 2023-07-07 上海交通大学 基于交替梯度下降算法的串扰荧光光谱分解方法
EP4481058A1 (de) * 2023-06-23 2024-12-25 QIAGEN GmbH Verfahren, verwendung und vorrichtung zur signalerfassung in einem prozess unter verwendung von fluoreszenz bei verschiedenen wellenlängen
KR20260028007A (ko) * 2023-06-30 2026-03-03 라이프 테크놀로지스 코포레이션 다중 qpcr 분석에서 스펙트럼 크로스토크를 감소시키기 위한 자동 스펙트럼 염료 행렬 조정
CN117434044B (zh) * 2023-12-19 2024-03-08 鲲鹏基因（北京）科技有限责任公司 一种pcr仪荧光串扰系数标定方法及装置与应用

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US5606164A (en) * 1996-01-16 1997-02-25 Boehringer Mannheim Corporation Method and apparatus for biological fluid analyte concentration measurement using generalized distance outlier detection
US6387621B1 (en) * 1999-04-27 2002-05-14 University Of Utah Research Foundation Automated analysis of real-time nucleic acid amplification
CA2380307A1 (en) * 1999-07-21 2001-02-01 Tropix, Inc. Luminescence detection workstation
AU2002308693A1 (en) * 2001-04-25 2002-11-05 Amnis Corporation Method and apparatus for correcting crosstalk and spatial resolution for multichannel imaging
US7435602B2 (en) * 2002-12-20 2008-10-14 Applied Biosystems Inc. Reducing effects of spectral nonuniformity
EP1798650A1 (de) * 2005-12-19 2007-06-20 Roche Diagnostics GmbH Analytisches Verfahren und Instrument
US7668663B2 (en) 2005-12-20 2010-02-23 Roche Molecular Systems, Inc. Levenberg-Marquardt outlier spike removal method
US7680868B2 (en) 2005-12-20 2010-03-16 Roche Molecular Systems, Inc. PCR elbow determination by use of a double sigmoid function curve fit with the Levenburg-Marquardt algorithm and normalization
EP2044432B1 (de) * 2006-06-28 2023-03-29 Life Technologies Corporation Minimierung von farbübersprechungseffekten

Also Published As

Publication number Publication date
CA2691907A1 (en) 2009-01-08
US8095322B2 (en) 2012-01-10
EP2160594A1 (de) 2010-03-10
JP5400768B2 (ja) 2014-01-29
CN101688841B (zh) 2011-12-07
US20090035779A1 (en) 2009-02-05
JP2010531649A (ja) 2010-09-30
CA2691907C (en) 2013-08-06
ES2370678T3 (es) 2011-12-21
HK1140261A1 (en) 2010-10-08
CN101688841A (zh) 2010-03-31
EP2160594B1 (de) 2011-08-03
WO2009003645A1 (en) 2009-01-08

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