ATE523508T1 - Für die behandlung von zellproliferativen erkrankungen geeignete pyridin- und pyrazinderivate - Google Patents

Für die behandlung von zellproliferativen erkrankungen geeignete pyridin- und pyrazinderivate

Info

Publication number
ATE523508T1
ATE523508T1 AT08841876T AT08841876T ATE523508T1 AT E523508 T1 ATE523508 T1 AT E523508T1 AT 08841876 T AT08841876 T AT 08841876T AT 08841876 T AT08841876 T AT 08841876T AT E523508 T1 ATE523508 T1 AT E523508T1
Authority
AT
Austria
Prior art keywords
pyridine
treatment
cell proliferative
proliferative diseases
pyrazine derivatives
Prior art date
Application number
AT08841876T
Other languages
English (en)
Inventor
Bernard Barlaam
Justin Bower
Benedicte Delouvrie
Gary Fairley
Craig Harris
Christine Lambert
Gilles Ouvry
Jon Winter
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE523508T1 publication Critical patent/ATE523508T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT08841876T 2007-10-25 2008-10-22 Für die behandlung von zellproliferativen erkrankungen geeignete pyridin- und pyrazinderivate ATE523508T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP07301491 2007-10-25
EP07305005 2007-12-21
EP08305180 2008-05-19
PCT/GB2008/050974 WO2009053737A2 (en) 2007-10-25 2008-10-22 Pyridine and pyrazine derivatives useful in the treatment of cell proliferative disorders

Publications (1)

Publication Number Publication Date
ATE523508T1 true ATE523508T1 (de) 2011-09-15

Family

ID=40580139

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08841876T ATE523508T1 (de) 2007-10-25 2008-10-22 Für die behandlung von zellproliferativen erkrankungen geeignete pyridin- und pyrazinderivate

Country Status (18)

Country Link
US (1) US8017611B2 (de)
EP (1) EP2215085B1 (de)
JP (1) JP2011500778A (de)
KR (1) KR20100089090A (de)
CN (1) CN101910158A (de)
AR (1) AR069078A1 (de)
AT (1) ATE523508T1 (de)
AU (1) AU2008315746A1 (de)
CA (1) CA2703653A1 (de)
CL (1) CL2008003188A1 (de)
CO (1) CO6270364A2 (de)
EC (1) ECSP10010197A (de)
IL (1) IL205108A0 (de)
MX (1) MX2010004491A (de)
PE (1) PE20091116A1 (de)
TW (1) TW200920367A (de)
UY (1) UY31430A1 (de)
WO (1) WO2009053737A2 (de)

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