ATE532523T1 - Zoledronsäure zur prävention oder verminderung von sekundärfrakturen nach hüftfraktur - Google Patents

Zoledronsäure zur prävention oder verminderung von sekundärfrakturen nach hüftfraktur

Info

Publication number: ATE532523T1
Authority: AT; Austria
Prior art keywords: prevent; hip fracture; zoledronic acid; reduce secondary; secondary fractures
Prior art date: 2002-09-16

Application number

AT03750546T

Other languages

English (en)

Inventor

Kenneth Lyles

Zebulun Horowitz

Original Assignee

Novartis Pharma Gmbh

Lyles Kenneth W

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-09-16

Filing date

2003-09-15

Publication date

2011-11-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31994241&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE532523(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-09-15 Application filed by Novartis Pharma Gmbh, Lyles Kenneth W filed Critical Novartis Pharma Gmbh

2011-11-15 Application granted granted Critical

2011-11-15 Publication of ATE532523T1 publication Critical patent/ATE532523T1/de

Links

206010020100 Hip fracture Diseases 0.000 title abstract 3
206010017076 Fracture Diseases 0.000 title abstract 2
XRASPMIURGNCCH-UHFFFAOYSA-N zoledronic acid Chemical compound OP(=O)(O)C(P(O)(O)=O)(O)CN1C=CN=C1 XRASPMIURGNCCH-UHFFFAOYSA-N 0.000 title 1
229960004276 zoledronic acid Drugs 0.000 title 1
229940122361 Bisphosphonate Drugs 0.000 abstract 1
208000001132 Osteoporosis Diseases 0.000 abstract 1
150000004663 bisphosphonates Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000001009 osteoporotic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Rheumatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Orthopedic Medicine & Surgery (AREA)
Inorganic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Plant Substances (AREA)
Steroid Compounds (AREA)

AT03750546T 2002-09-16 2003-09-15 Zoledronsäure zur prävention oder verminderung von sekundärfrakturen nach hüftfraktur ATE532523T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US41106702P	2002-09-16	2002-09-16
PCT/EP2003/010239 WO2004024166A1 (en)	2002-09-16	2003-09-15	Method for preventing or reducing secondary fractures after hip fracture

Publications (1)

Publication Number	Publication Date
ATE532523T1 true ATE532523T1 (de)	2011-11-15

Family

ID=31994241

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03750546T ATE532523T1 (de)	2002-09-16	2003-09-15	Zoledronsäure zur prävention oder verminderung von sekundärfrakturen nach hüftfraktur

Country Status (12)

Country	Link
US (2)	US20050272707A1 (de)
EP (1)	EP1542700B1 (de)
JP (1)	JP2006500402A (de)
CN (1)	CN1681516A (de)
AT (1)	ATE532523T1 (de)
AU (1)	AU2003270196A1 (de)
BR (1)	BR0314362A (de)
CA (1)	CA2497353C (de)
ES (1)	ES2376425T3 (de)
PT (1)	PT1542700E (de)
TW (1)	TWI344367B (de)
WO (1)	WO2004024166A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2005117906A1 (en) *	2004-05-19	2005-12-15	Merck & Co., Inc.	Combination for inhibiting bone resorption comprising a bisphosponate (alendrona) and a vitamin d (cholecalciferol)
US8071574B2 (en)	2005-02-22	2011-12-06	John Dennis Bobyn	Implant improving local bone formation
US7473684B2 (en)	2005-09-16	2009-01-06	Selamine Limited	Bisphosphonate formulation
EP1972341A1 (de) *	2007-03-23	2008-09-24	Novartis AG	Bisphosphonate und Vitamin D enthaltende Pharmazeutische Zusammensetzungen
WO2009121935A2 (en) *	2008-04-04	2009-10-08	Novartis Ag	Pharmaceutical composition with bisphosphonate
DK2473172T3 (en) *	2009-09-01	2015-06-15	Univ Duke	BISPHOSPHONATSAMMENSÆTNINGER and Methods for treating congestive heart failure
WO2013074587A1 (en)	2011-11-16	2013-05-23	Duke University	Bishophonate compositions and methods for treating and/or reducing cardiac dysfunction
RU2542425C1 (ru) *	2013-09-23	2015-02-20	Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ")	Способ коррекции микроциркуляции в костной ткани при экспериментальном остеопорозе и переломах на его фоне комбинацией l-аргинина и лозартана
RU2540927C1 (ru) *	2013-09-23	2015-02-10	Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ")	Способ коррекции микроциркуляции в костной ткани при экспериментальном остеопорозе и переломах на его фоне комбинацией l-норвалина и розувастатина
RU2538612C1 (ru) *	2013-09-23	2015-01-10	Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ")	Способ коррекции микроциркуляции в костной ткани при экспериментальном остеопорозе и переломах на его фоне розувастатином
RU2542424C1 (ru) *	2013-09-23	2015-02-20	Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ")	Способ коррекции микроциркуляции в костной ткани при экспериментальном остеопорозе и переломах на его фоне комбинацией l-аргинина и эналаприла
RU2540926C1 (ru) *	2013-09-23	2015-02-10	Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ")	Способ коррекции микроциркуляции в костной ткани при экспериментальном остеопорозе и переломах на его фоне l-норвалином
PT3246032T (pt) *	2016-05-20	2021-10-18	Christoph Karl	Composições farmacêuticas com ácido zoledrónico, cálcio e vitamina d adequadas para tratamento e/ou profilaxia de doenças do metabolismo ósseo e de efeitos secundários relacionados com terapia, como hipocalcemias

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3776880D1 (de) *	1986-11-21	1992-04-02	Ciba Geigy Ag	Neue substituierte alkandiphosphonsaeuren.
AU670337B2 (en) *	1992-11-30	1996-07-11	Novartis Ag	Use of certain methanebisphosphonic acid derivatives in fracture healing
GB9408775D0 (en) *	1994-05-04	1994-06-22	Ciba Geigy Ag	Use of certain methanebisphosphonic acid derivatives to prevent prothesis loosening and prothesis migration
GB0012209D0 (en) *	2000-05-19	2000-07-12	Novartis Ag	Organic compounds
CA2410201C (en) *	2000-06-20	2010-10-26	Novartis Ag	Zoledronic acid or salts thereof for use in the treatment of conditions of abnormally increased bone turnover

2003
- 2003-09-15 CA CA2497353A patent/CA2497353C/en not_active Expired - Fee Related
- 2003-09-15 ES ES03750546T patent/ES2376425T3/es not_active Expired - Lifetime
- 2003-09-15 EP EP03750546A patent/EP1542700B1/de not_active Revoked
- 2003-09-15 AU AU2003270196A patent/AU2003270196A1/en not_active Abandoned
- 2003-09-15 TW TW092125357A patent/TWI344367B/zh not_active IP Right Cessation
- 2003-09-15 CN CNA038218828A patent/CN1681516A/zh active Pending
- 2003-09-15 WO PCT/EP2003/010239 patent/WO2004024166A1/en not_active Ceased
- 2003-09-15 AT AT03750546T patent/ATE532523T1/de active
- 2003-09-15 BR BR0314362-7A patent/BR0314362A/pt not_active IP Right Cessation
- 2003-09-15 PT PT03750546T patent/PT1542700E/pt unknown
- 2003-09-15 US US10/527,883 patent/US20050272707A1/en not_active Abandoned
- 2003-09-15 JP JP2004535511A patent/JP2006500402A/ja active Pending
2008
- 2008-04-16 US US12/104,243 patent/US20080193564A1/en not_active Abandoned

Also Published As

Publication number	Publication date
TW200412979A (en)	2004-08-01
ES2376425T3 (es)	2012-03-13
HK1079431A1 (en)	2006-04-07
AU2003270196A1 (en)	2004-04-30
BR0314362A (pt)	2005-07-19
TWI344367B (en)	2011-07-01
CN1681516A (zh)	2005-10-12
PT1542700E (pt)	2012-02-01
CA2497353A1 (en)	2004-03-25
EP1542700A1 (de)	2005-06-22
CA2497353C (en)	2012-08-28
US20080193564A1 (en)	2008-08-14
WO2004024166A1 (en)	2004-03-25
EP1542700B1 (de)	2011-11-09
JP2006500402A (ja)	2006-01-05
US20050272707A1 (en)	2005-12-08

Publication	Publication Date	Title
ATE532523T1 (de)	2011-11-15	Zoledronsäure zur prävention oder verminderung von sekundärfrakturen nach hüftfraktur
ATE460893T1 (de)	2010-04-15	Orthopädische platten- und knochenschraubenanordnung
BR9909445A (pt)	2000-12-12	Método para aumentar a rigidez e resistência óssea e reduzir fraturas
BR0318600A (pt)	2006-10-17	conjunto implantável para osteossìntese, e, conjunto com pelo menos duas placas de osteossìntese e parafusos ósseos
CA2495110A1 (en)	2004-02-19	Method and apparatus for repairing the mid-foot region via an intramedullary nail
ATE295734T1 (de)	2005-06-15	Verwendung von fibroblasten-wachstumsfaktor analogen zur stimulation des knochenwachstums
WO2007120539A3 (en)	2008-05-02	Orthopedic device
DK0881908T3 (da)	2004-10-25	Anvendelse af fiberblastvækstfaktorer til stimulering af knoglevækst
DE60233803D1 (de)	2009-11-05	5-cnac zur oralen verabreichung von parathormonfragmenten
WO2005016265A3 (en)	2005-07-07	Method for promoting bone growth
ATE275580T1 (de)	2004-09-15	Verfahren zur induktion der herstellung von wachstumsfaktoren
EA201001097A1 (ru)	2011-02-28	Фармацевтическая композиция для профилактики и лечения резорбции костной ткани различной этиологии
MD37Z (ro)	2010-01-31	Metodă de tratament al pseudartrozei
UA34163A (uk)	2001-02-15	Спосіб стимулювання остеогенезу при хірургічних втручаннях на кістках щелепи
RU2010114106A (ru)	2011-10-20	Способ лечения перелома проксимального отдела плеча при тяжелой форме остеопороза
WO2006123279A3 (en)	2007-02-22	Natural drugs containing calcium and phosphate and apparatus for iontophoretic treatment of osteoporosis
Lu et al.	2016	Subtrochanteric fracture non-union with implant failure managed with exchange intramedullary nail with autogenous bone graft and supplement of bone morphogenic protein
CN205073011U (zh)	2016-03-09	骨折内固定钉
Moya-Angeler	2016	Alendronic acid/ibandronic acid/pantoprazole
SU et al.	2018	Effect analysis of posterolateral combined with posteromedial approach in patients with posterior Pilon fracture
Shetty et al.	2015	Surgical Management of Long Bone Fracture of Lower Limb in Pediatric by Titanium Elastic Nails.
MD2000F1 (en)	2002-09-30	Method of reconstruction of viciously consolidated distal humerus metaphyseal fractures to children
UA31493U (uk)	2008-04-10	Спосіб лікування остеопорозу
UA5996U (en)	2005-04-15	Method for surgical treatment of deforming arthrosis of the first metatarsophalangeal joint
Hofmann	2003	Retrograde nailing in high tibial fractures