ATE540127T1 - Multiplex pcr - Google Patents

Multiplex pcr

Info

Publication number: ATE540127T1
Authority: AT; Austria
Prior art keywords: templates; multiplex pcr; appending; distinct sequence; nucleic acid
Prior art date: 2001-11-19

Application number

AT02803689T

Other languages

English (en)

Inventor

Malek Faham

Eugeni Anatolyevich Namsaraev

Thomas Willis

Original Assignee

Affymetrix Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-19

Filing date

2002-11-19

Publication date

2012-01-15

2002-11-19 Application filed by Affymetrix Inc filed Critical Affymetrix Inc

2012-01-15 Application granted granted Critical

2012-01-15 Publication of ATE540127T1 publication Critical patent/ATE540127T1/de

Links

238000007403 mPCR Methods 0.000 title 1
108091034117 Oligonucleotide Proteins 0.000 abstract 1
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
230000003321 amplification Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000003199 nucleic acid amplification method Methods 0.000 abstract 1
108020004707 nucleic acids Proteins 0.000 abstract 1
150000007523 nucleic acids Chemical class 0.000 abstract 1
102000039446 nucleic acids Human genes 0.000 abstract 1
230000037452 priming Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Microbiology (AREA)
Biophysics (AREA)
Analytical Chemistry (AREA)
Physics & Mathematics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT02803689T 2001-11-19 2002-11-19 Multiplex pcr ATE540127T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US33169301P	2001-11-19	2001-11-19
PCT/US2002/037238 WO2003044177A2 (en)	2001-11-19	2002-11-19	Multiplex pcr

Publications (1)

Publication Number	Publication Date
ATE540127T1 true ATE540127T1 (de)	2012-01-15

Family

ID=23294970

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT02803690T ATE425263T1 (de)	2001-11-19	2002-11-19	Multiplex-oligonukleotidaddition und zielamplifikation
AT02803689T ATE540127T1 (de)	2001-11-19	2002-11-19	Multiplex pcr

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT02803690T ATE425263T1 (de)	2001-11-19	2002-11-19	Multiplex-oligonukleotidaddition und zielamplifikation

Country Status (9)

Country	Link
US (3)	US7208295B2 (de)
EP (2)	EP1456416B1 (de)
JP (2)	JP2005509440A (de)
CN (2)	CN100396788C (de)
AT (2)	ATE425263T1 (de)
AU (2)	AU2002366099A1 (de)
CA (2)	CA2467577A1 (de)
DE (1)	DE60231543D1 (de)
WO (2)	WO2003044177A2 (de)

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2002
- 2002-11-19 US US10/300,311 patent/US7208295B2/en not_active Expired - Lifetime
- 2002-11-19 AT AT02803690T patent/ATE425263T1/de not_active IP Right Cessation
- 2002-11-19 US US10/300,285 patent/US7510829B2/en not_active Expired - Fee Related
- 2002-11-19 EP EP02803690A patent/EP1456416B1/de not_active Expired - Lifetime
- 2002-11-19 WO PCT/US2002/037238 patent/WO2003044177A2/en not_active Ceased
- 2002-11-19 WO PCT/US2002/037239 patent/WO2003044216A2/en not_active Ceased
- 2002-11-19 AU AU2002366099A patent/AU2002366099A1/en not_active Abandoned
- 2002-11-19 CA CA002467577A patent/CA2467577A1/en not_active Abandoned
- 2002-11-19 CN CNB028265912A patent/CN100396788C/zh not_active Expired - Fee Related
- 2002-11-19 JP JP2003545837A patent/JP2005509440A/ja active Pending
- 2002-11-19 EP EP02803689A patent/EP1453979B1/de not_active Expired - Lifetime
- 2002-11-19 AU AU2002366098A patent/AU2002366098A1/en not_active Abandoned
- 2002-11-19 JP JP2003545802A patent/JP2005509433A/ja active Pending
- 2002-11-19 CA CA002467460A patent/CA2467460A1/en not_active Abandoned
- 2002-11-19 DE DE60231543T patent/DE60231543D1/de not_active Expired - Fee Related
- 2002-11-19 CN CNA028265955A patent/CN1697882A/zh active Pending
- 2002-11-19 AT AT02803689T patent/ATE540127T1/de active
2007
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Also Published As

Publication number	Publication date
US20030104459A1 (en)	2003-06-05
JP2005509433A (ja)	2005-04-14
EP1456416A2 (de)	2004-09-15
WO2003044177A2 (en)	2003-05-30
CA2467577A1 (en)	2003-05-30
EP1456416A4 (de)	2006-01-11
US20030096291A1 (en)	2003-05-22
EP1453979B1 (de)	2012-01-04
AU2002366099A1 (en)	2003-06-10
EP1453979A4 (de)	2005-12-28
WO2003044216A3 (en)	2003-08-14
DE60231543D1 (de)	2009-04-23
WO2003044177A3 (en)	2003-08-28
WO2003044216A2 (en)	2003-05-30
US7510829B2 (en)	2009-03-31
AU2002366098A1 (en)	2003-06-10
CA2467460A1 (en)	2003-05-30
EP1453979A2 (de)	2004-09-08
CN1697882A (zh)	2005-11-16
CN100396788C (zh)	2008-06-25
EP1456416B1 (de)	2009-03-11
US7754451B2 (en)	2010-07-13
US7208295B2 (en)	2007-04-24
US20090004701A1 (en)	2009-01-01
ATE425263T1 (de)	2009-03-15
CN1610758A (zh)	2005-04-27
JP2005509440A (ja)	2005-04-14

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