|
US5496280A
(en)
|
1992-07-02 |
1996-03-05 |
Applied Medical Resources Corporation |
Trocar valve assembly
|
|
GB0420722D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
|
AR059898A1
(es)
|
2006-03-15 |
2008-05-07 |
Janssen Pharmaceutica Nv |
Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
|
|
ES2320955B1
(es)
*
|
2007-03-02 |
2010-03-16 |
Laboratorios Almirall S.A. |
Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida.
|
|
TW200900065A
(en)
|
2007-03-07 |
2009-01-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
|
|
TW200845978A
(en)
|
2007-03-07 |
2008-12-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
|
|
ES2329639B1
(es)
|
2007-04-26 |
2010-09-23 |
Laboratorios Almirall S.A. |
Nuevos derivados de 4,8-difenilpoliazanaftaleno.
|
|
CN101801930B
(zh)
|
2007-09-14 |
2013-01-30 |
奥梅-杨森制药有限公司 |
1,3-二取代的-4-苯基-1h-吡啶-2-酮
|
|
SI2203439T1
(sl)
|
2007-09-14 |
2011-05-31 |
Ortho Mcneil Janssen Pharm |
1',3'-disubstituirani 4-fenil-3,4,5,6-tetrahidro-2H-1'H-(1,4')bipiridinil-2'-oni
|
|
PL2200985T3
(pl)
|
2007-09-14 |
2011-12-30 |
Ortho Mcneil Janssen Pharmaceuticals Inc |
1,3-Dipodstawione-4-(arylo-X-fenylo)-1H-pirydyn-2-ony
|
|
CN101861316B
(zh)
|
2007-11-14 |
2013-08-21 |
奥梅-杨森制药有限公司 |
咪唑并[1,2-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途
|
|
EP2108641A1
(de)
|
2008-04-11 |
2009-10-14 |
Laboratorios Almirall, S.A. |
Neue substituierte Spiro[Cycloalkyl-1,3'-indo]-2'(1'H)-on-Derivate und ihre Verwendung als p38 mitogen-activated Kinase Inhibitoren
|
|
EP2113503A1
(de)
*
|
2008-04-28 |
2009-11-04 |
Laboratorios Almirall, S.A. |
Neue substituierte Indolin-2-on- Derivate und ihre Verwendung als p39 mitogen-activated Kinase Inhibitoren
|
|
EP2344470B1
(de)
|
2008-09-02 |
2013-11-06 |
Janssen Pharmaceuticals, Inc. |
3-azabicyclo[3.1.0]hexylderivate als modulatoren von metabotropen glutamatrezeptoren
|
|
WO2010043396A1
(en)
|
2008-10-16 |
2010-04-22 |
Ortho-Mcneil-Janssen Pharmaceuticals, Inc. |
Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors
|
|
JP5690277B2
(ja)
|
2008-11-28 |
2015-03-25 |
ジャンセン ファーマシューティカルズ, インコーポレイテッド. |
代謝型グルタミン酸受容体の調節因子としてのインドールおよびベンゾオキサジン誘導体
|
|
MY153913A
(en)
|
2009-05-12 |
2015-04-15 |
Janssen Pharmaceuticals Inc |
7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
|
|
BRPI1010831A2
(pt)
|
2009-05-12 |
2016-04-05 |
Addex Pharmaceuticals Sa |
derivados de 1,2,4-triazolo[4,3-a]piridina e seu como moduladores alostéricos positivos de receptores de mglur2
|
|
CN102439008B
(zh)
|
2009-05-12 |
2015-04-29 |
杨森制药有限公司 |
1,2,4-三唑并[4,3-a]吡啶衍生物及其用于治疗或预防神经和精神病症的用途
|
|
EP2438066A2
(de)
|
2009-06-05 |
2012-04-11 |
Cephalon, Inc. |
Zubereitung und verwendung von 1,2,4-triazol [1,5a]pyridinderivaten
|
|
EP2322176A1
(de)
*
|
2009-11-11 |
2011-05-18 |
Almirall, S.A. |
Neue 7-Phenyl-[1,2,4]triazol[4,3-a]pyridin-3(2H)on-Derivate
|
|
EP2338888A1
(de)
*
|
2009-12-24 |
2011-06-29 |
Almirall, S.A. |
Imidazopyridin-Derivate als JAK-Inhibitoren
|
|
UY33213A
(es)
|
2010-02-18 |
2011-09-30 |
Almirall Sa |
Derivados de pirazol como inhibidores de jak
|
|
ES2536433T3
(es)
|
2010-11-08 |
2015-05-25 |
Janssen Pharmaceuticals, Inc. |
Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2
|
|
US9271967B2
(en)
|
2010-11-08 |
2016-03-01 |
Janssen Pharmaceuticals, Inc. |
1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
|
|
AU2011328203B2
(en)
|
2010-11-08 |
2015-03-19 |
Janssen Pharmaceuticals, Inc. |
1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
|
|
JP5951625B2
(ja)
|
2010-11-24 |
2016-07-13 |
ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨークThe Trustees Of Columbia University In The City Of New York |
加齢性黄斑変性症およびシュタルガルト病の処置のための非レチノイドrbp4アンタゴニスト
|
|
EP2463289A1
(de)
|
2010-11-26 |
2012-06-13 |
Almirall, S.A. |
Imidazo[1,2-b]Pyridazin-Derivate als AS JAK-Hemmer
|
|
EP2554544A1
(de)
|
2011-08-01 |
2013-02-06 |
Almirall, S.A. |
Pyridin-2(1H-)-on-Derivate als JAK-Inhibitoren
|
|
US9630929B2
(en)
|
2011-10-31 |
2017-04-25 |
Xenon Pharmaceuticals Inc. |
Benzenesulfonamide compounds and their use as therapeutic agents
|
|
JP6014155B2
(ja)
|
2011-10-31 |
2016-10-25 |
ゼノン・ファーマシューティカルズ・インコーポレイテッドXenon Pharmaceuticals Inc. |
ビアリールエーテルスルホンアミドおよび治療剤としてのそれらの使用
|
|
US10531655B2
(en)
|
2011-12-02 |
2020-01-14 |
The Regents Of The University Of California |
Reperfusion protection solution and uses thereof
|
|
US9333202B2
(en)
|
2012-05-01 |
2016-05-10 |
The Trustees Of Columbia University In The City Of New York |
Non-retinoid antagonists for treatment of age-related macular degeneration and stargardt disease
|
|
SG11201408284VA
(en)
|
2012-05-22 |
2015-02-27 |
Xenon Pharmaceuticals Inc |
N-substituted benzamides and their use in the treatment of pain
|
|
US10071957B2
(en)
|
2012-07-06 |
2018-09-11 |
Genentech, Inc. |
N-substituted benzamides and methods of use thereof
|
|
JP6430383B2
(ja)
*
|
2012-09-28 |
2018-11-28 |
ヴァンダービルト ユニバーシティーVanderbilt University |
選択的bmp阻害剤としての縮合複素環化合物
|
|
US9944644B2
(en)
|
2013-03-14 |
2018-04-17 |
The Trustees Of Columbia University In The City Of New York |
Octahydropyrrolopyrroles their preparation and use
|
|
EP3495357B1
(de)
|
2013-03-14 |
2021-05-05 |
The Trustees of Columbia University in the City of New York |
4-phenylpiperidine, deren herstellung und verwendung
|
|
WO2014152018A1
(en)
|
2013-03-14 |
2014-09-25 |
The Trustees Of Columbia University In The City Of New York |
Octahydrocyclopentapyrroles, their preparation and use
|
|
US9550775B2
(en)
|
2013-03-14 |
2017-01-24 |
Genentech, Inc. |
Substituted triazolopyridines and methods of use thereof
|
|
US9938291B2
(en)
|
2013-03-14 |
2018-04-10 |
The Trustess Of Columbia University In The City Of New York |
N-alkyl-2-phenoxyethanamines, their preparation and use
|
|
MX2015010775A
(es)
|
2013-03-15 |
2016-04-25 |
Genentech Inc |
Benzoxazoles sustituidos y metodos para usarlos.
|
|
JO3368B1
(ar)
|
2013-06-04 |
2019-03-13 |
Janssen Pharmaceutica Nv |
مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
|
|
JO3367B1
(ar)
|
2013-09-06 |
2019-03-13 |
Janssen Pharmaceutica Nv |
مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
|
|
CR20160296A
(es)
|
2013-11-27 |
2016-09-20 |
Genentech Inc |
Benzamidas sustituidas y métodos para usarlas
|
|
GB201321740D0
(en)
|
2013-12-09 |
2014-01-22 |
Ucb Pharma Sa |
Therapeutic agents
|
|
GB201321742D0
(en)
*
|
2013-12-09 |
2014-01-22 |
Ucb Pharma Sa |
Therapeutic agents
|
|
MX386697B
(es)
|
2014-01-21 |
2025-03-19 |
Janssen Pharmaceutica Nv |
Combinaciones que comprenden agonistas ortostericos o moduladores alostericos positivos del receptor glutamatergico metabotropico de subtipo 2 y su uso
|
|
ME03518B
(de)
|
2014-01-21 |
2020-04-20 |
Janssen Pharmaceutica Nv |
Kombinationen mit positiven allosterischen modulatoren von metabotropem glutamatergen rezeptor vom subtyp 2 und deren verwendung
|
|
US9527835B2
(en)
|
2014-02-13 |
2016-12-27 |
Incyte Corporation |
Cyclopropylamines as LSD1 inhibitors
|
|
EP3105219B9
(de)
|
2014-02-13 |
2018-10-03 |
Incyte Corporation |
Cyclopropylamine als lsd1-hemmer
|
|
JP6602779B2
(ja)
|
2014-02-13 |
2019-11-06 |
インサイト・コーポレイション |
Lsd1阻害剤としてのシクロプロピルアミン類
|
|
EP3105218B1
(de)
|
2014-02-13 |
2019-09-25 |
Incyte Corporation |
Cyclopropylamine als lsd1-hemmer
|
|
SG11201608943VA
(en)
|
2014-04-30 |
2016-11-29 |
Univ Columbia |
Substituted 4-phenylpiperidines, their preparaiton and use
|
|
CN106715418A
(zh)
|
2014-07-07 |
2017-05-24 |
基因泰克公司 |
治疗化合物及其使用方法
|
|
WO2016007731A1
(en)
|
2014-07-10 |
2016-01-14 |
Incyte Corporation |
Imidazopyridines and imidazopyrazines as lsd1 inhibitors
|
|
US9758523B2
(en)
|
2014-07-10 |
2017-09-12 |
Incyte Corporation |
Triazolopyridines and triazolopyrazines as LSD1 inhibitors
|
|
US9695167B2
(en)
|
2014-07-10 |
2017-07-04 |
Incyte Corporation |
Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors
|
|
US9695180B2
(en)
|
2014-07-10 |
2017-07-04 |
Incyte Corporation |
Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors
|
|
KR20170095814A
(ko)
|
2014-10-06 |
2017-08-23 |
플랫틀리 디스커버리 랩, 엘엘씨 |
트라이아졸로피리딘 화합물 및 낭성 섬유증의 치료 방법
|
|
EP3277689B1
(de)
|
2015-04-03 |
2019-09-04 |
Incyte Corporation |
Heterocyclische verbindungen als lsd1-hemmer
|
|
EP3088390A1
(de)
*
|
2015-04-30 |
2016-11-02 |
Bayer CropScience AG |
Katalytische hydrierung von substituierten cyanopyridinen
|
|
JP2018520107A
(ja)
|
2015-05-22 |
2018-07-26 |
ジェネンテック, インコーポレイテッド |
置換ベンズアミド及びその使用方法
|
|
MY189367A
(en)
|
2015-08-12 |
2022-02-08 |
Incyte Corp |
Salts of an lsd1 inhibitor
|
|
EP3341353A1
(de)
|
2015-08-27 |
2018-07-04 |
Genentech, Inc. |
Therapeutische verbindungen und verfahren zur verwendung davon
|
|
CN108290881B
(zh)
|
2015-09-28 |
2021-12-07 |
健泰科生物技术公司 |
治疗性化合物和其使用方法
|
|
US10899732B2
(en)
|
2015-11-25 |
2021-01-26 |
Genentech, Inc. |
Substituted benzamides useful as sodium channel blockers
|
|
EP3854782A1
(de)
|
2016-03-30 |
2021-07-28 |
Genentech, Inc. |
Substituierte benzamide und verfahren zur verwendung davon
|
|
TWI833686B
(zh)
|
2016-04-22 |
2024-03-01 |
美商英塞特公司 |
Lsd1 抑制劑之調配物
|
|
AU2017347549A1
(en)
|
2016-10-17 |
2019-05-02 |
Genentech, Inc. |
Therapeutic compounds and methods of use thereof
|
|
JP2020511511A
(ja)
|
2017-03-24 |
2020-04-16 |
ジェネンテック, インコーポレイテッド |
ナトリウムチャネル阻害剤としての4−ピペリジン−n−(ピリミジン−4−イル)クロマン−7−スルホンアミド誘導体
|
|
CN111051305A
(zh)
*
|
2017-08-22 |
2020-04-21 |
吉利德科学公司 |
治疗性杂环化合物
|
|
BR112020006677A2
(pt)
|
2017-10-05 |
2020-10-06 |
Fulcrum Therapeutics, Inc. |
uso de inibidores p38 para reduzir a expressão de dux4
|
|
US10342786B2
(en)
|
2017-10-05 |
2019-07-09 |
Fulcrum Therapeutics, Inc. |
P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
|
|
AR114263A1
(es)
|
2018-02-26 |
2020-08-12 |
Genentech Inc |
Compuestos terapéuticos y métodos para utilizarlos
|
|
WO2019178383A1
(en)
|
2018-03-14 |
2019-09-19 |
Vanderbilt University |
Inhibition of bmp signaling, compounds, compositions and uses thereof
|
|
WO2019191702A1
(en)
|
2018-03-30 |
2019-10-03 |
F. Hoffmann-La Roche Ag |
Substituted hydro-pyrido-azines as sodium channel inhibitors
|
|
TW202003490A
(zh)
|
2018-05-22 |
2020-01-16 |
瑞士商赫孚孟拉羅股份公司 |
治療性化合物及其使用方法
|
|
US10968200B2
(en)
|
2018-08-31 |
2021-04-06 |
Incyte Corporation |
Salts of an LSD1 inhibitor and processes for preparing the same
|
|
CN111116582B
(zh)
*
|
2019-12-18 |
2022-07-29 |
大连大学 |
一种mGluR2拮抗剂
|
|
CN114516870B
(zh)
*
|
2022-02-10 |
2023-04-11 |
五邑大学 |
一种三唑并六元氮杂环-3-胺类化合物及其制备方法和应用
|