ATE549319T1 - Verfahren zur herstellung eines 2-nitroimidazol- derivats - Google Patents

Verfahren zur herstellung eines 2-nitroimidazol- derivats

Info

Publication number
ATE549319T1
ATE549319T1 AT08702779T AT08702779T ATE549319T1 AT E549319 T1 ATE549319 T1 AT E549319T1 AT 08702779 T AT08702779 T AT 08702779T AT 08702779 T AT08702779 T AT 08702779T AT E549319 T1 ATE549319 T1 AT E549319T1
Authority
AT
Austria
Prior art keywords
producing
nitroimidazole
benzoyloxymethyl
derivative
benzoylglycerin
Prior art date
Application number
AT08702779T
Other languages
English (en)
Inventor
Azuma Nishio
Original Assignee
Pola Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pola Pharma Inc filed Critical Pola Pharma Inc
Application granted granted Critical
Publication of ATE549319T1 publication Critical patent/ATE549319T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT08702779T 2007-01-23 2008-01-17 Verfahren zur herstellung eines 2-nitroimidazol- derivats ATE549319T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007012147 2007-01-23
PCT/JP2008/000038 WO2008090731A1 (ja) 2007-01-23 2008-01-17 ２－ニトロイミダゾール誘導体の製造法

Publications (1)

Publication Number Publication Date
ATE549319T1 true ATE549319T1 (de) 2012-03-15

Family

ID=39644306

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08702779T ATE549319T1 (de) 2007-01-23 2008-01-17 Verfahren zur herstellung eines 2-nitroimidazol- derivats

Country Status (7)

Country Link
US (1) US8030338B2 (de)
EP (1) EP2128140B1 (de)
JP (1) JP5213178B2 (de)
KR (1) KR101408677B1 (de)
AT (1) ATE549319T1 (de)
TW (1) TWI452036B (de)
WO (1) WO2008090731A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4658268B2 (ja) 2008-11-26 2011-03-23 三菱電機株式会社 電力用半導体モジュール
RU2475875C2 (ru) * 2010-12-27 2013-02-20 Федеральное государственное унитарное предприятие "Государственный научный центр Российской Федерации - Физико-энергетический институт имени А.И. Лейпунского" Способ нанесения радиоизотопа на вогнутую металлическую поверхность подложки закрытого источника излучения
MD4150C1 (ro) * 2011-10-11 2012-09-30 Институт Химии Академии Наук Молдовы Procedeu de obţinere a compuşilor coordinativi ai Co(II), Ni(II) şi Zn(II) cu 2-nitro-4,5-difenilimidazol pornind de la 4,5-difenilimidazol şi nitraţii metalelor respective
MD4178C1 (ro) * 2012-02-27 2013-02-28 Институт Химии Академии Наук Молдовы Procedeu de obţinere a 2-nitro-4,5-difenilimidazolului
CN116120262B (zh) * 2023-02-24 2025-04-18 宁德时代新能源科技股份有限公司 氟代环状醚的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0819111B2 (ja) * 1987-10-22 1996-02-28 ポーラ化成工業株式会社 ２―ニトロイミダゾール誘導体及びこれを有効成分とする放射線増感剤
JPH0248549A (ja) 1988-08-09 1990-02-19 Kawaken Fine Chem Co Ltd １，３−ジアセトキシ−２−アセトキシメトキシプロパンの製造方法
JP2626727B2 (ja) 1990-01-26 1997-07-02 ポーラ化成工業株式会社 ２―ニトロイミダゾール誘導体、その製造法及びこれを有効成分とする放射線増感剤
JP3223258B2 (ja) 1992-06-24 2001-10-29 株式会社キーエンス 稼働状態監視装置
JPH06228123A (ja) 1993-02-03 1994-08-16 Pola Chem Ind Inc ２−ニトロイミダゾール誘導体の製造法
JPH06279415A (ja) 1993-03-25 1994-10-04 Pola Chem Ind Inc 低酸素性細胞放射線増感剤
JP3989997B2 (ja) * 1997-04-08 2007-10-10 ポーラ化成工業株式会社 放射線増感剤の製造方法
JP4116793B2 (ja) * 1999-09-13 2008-07-09 良尋 高井 新規ニトロイミダゾール誘導体及びこれを含む画像診断薬
JP2005538030A (ja) 2000-06-21 2005-12-15 デュポン ファーマシューティカルズ カンパニー 組み合わせ療法での使用のための血管新生障害の画像診断用医薬

Also Published As

Publication number Publication date
EP2128140B1 (de) 2012-03-14
KR101408677B1 (ko) 2014-06-17
EP2128140A1 (de) 2009-12-02
US20100004460A1 (en) 2010-01-07
WO2008090731A1 (ja) 2008-07-31
JPWO2008090731A1 (ja) 2010-05-20
KR20090101453A (ko) 2009-09-28
TW200938527A (en) 2009-09-16
US8030338B2 (en) 2011-10-04
TWI452036B (zh) 2014-09-11
EP2128140A4 (de) 2010-08-11
JP5213178B2 (ja) 2013-06-19

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