ATE555216T1 - Umgebungstemperaturstabile kits für die molekulare diagnostik - Google Patents
Umgebungstemperaturstabile kits für die molekulare diagnostikInfo
- Publication number
- ATE555216T1 ATE555216T1 AT07762310T AT07762310T ATE555216T1 AT E555216 T1 ATE555216 T1 AT E555216T1 AT 07762310 T AT07762310 T AT 07762310T AT 07762310 T AT07762310 T AT 07762310T AT E555216 T1 ATE555216 T1 AT E555216T1
- Authority
- AT
- Austria
- Prior art keywords
- ambient temperature
- temperature stable
- solution mixture
- molecular diagnostics
- kits
- Prior art date
Links
- 239000000203 mixture Substances 0.000 abstract 5
- 239000000243 solution Substances 0.000 abstract 5
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 abstract 2
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 abstract 2
- 230000036571 hydration Effects 0.000 abstract 2
- 238000006703 hydration reaction Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000003321 amplification Effects 0.000 abstract 1
- 239000007853 buffer solution Substances 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Investigating Or Analyzing Materials Using Thermal Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80251006P | 2006-05-23 | 2006-05-23 | |
| PCT/US2007/069566 WO2007137291A1 (en) | 2006-05-23 | 2007-05-23 | Ambient temperature stable kits for molecular diagnostics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE555216T1 true ATE555216T1 (de) | 2012-05-15 |
Family
ID=38723635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07762310T ATE555216T1 (de) | 2006-05-23 | 2007-05-23 | Umgebungstemperaturstabile kits für die molekulare diagnostik |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20080050737A1 (de) |
| EP (2) | EP2210955A3 (de) |
| JP (2) | JP2009538146A (de) |
| AT (1) | ATE555216T1 (de) |
| CA (1) | CA2653454A1 (de) |
| WO (1) | WO2007137291A1 (de) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090098527A1 (en) * | 2006-09-12 | 2009-04-16 | Fischer Gerald W | Biological organism identification product and methods |
| US9481912B2 (en) | 2006-09-12 | 2016-11-01 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for detecting and identifying nucleic acid sequences in biological samples |
| US8080645B2 (en) * | 2007-10-01 | 2011-12-20 | Longhorn Vaccines & Diagnostics Llc | Biological specimen collection/transport compositions and methods |
| US8097419B2 (en) * | 2006-09-12 | 2012-01-17 | Longhorn Vaccines & Diagnostics Llc | Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009 |
| US8652782B2 (en) | 2006-09-12 | 2014-02-18 | Longhorn Vaccines & Diagnostics, Llc | Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids |
| US9683256B2 (en) | 2007-10-01 | 2017-06-20 | Longhorn Vaccines And Diagnostics, Llc | Biological specimen collection and transport system |
| US11041215B2 (en) | 2007-08-24 | 2021-06-22 | Longhorn Vaccines And Diagnostics, Llc | PCR ready compositions and methods for detecting and identifying nucleic acid sequences |
| US10004799B2 (en) | 2007-08-27 | 2018-06-26 | Longhorn Vaccines And Diagnostics, Llc | Composite antigenic sequences and vaccines |
| CA2976814C (en) | 2007-08-27 | 2022-12-13 | Longhorn Vaccines & Diagnostics, Llc | Immunogenic compositions and methods for treating influenza |
| EP2195466B1 (de) | 2007-10-01 | 2012-10-10 | Longhorn Vaccines & Diagnostics, LLC | Verfahren zum aufbewahren biologischer proben |
| US11041216B2 (en) | 2007-10-01 | 2021-06-22 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for detecting and quantifying nucleic acid sequences in blood samples |
| KR101098764B1 (ko) * | 2007-10-29 | 2011-12-26 | (주)바이오니아 | 안정화된 핫스타트 pcr용 건조 조성물 |
| KR100978215B1 (ko) * | 2008-02-28 | 2010-08-26 | 주식회사 인트론바이오테크놀로지 | 건조형태의 pcr 반응용 조성물에 기반한 pcr의 최적증폭 조건 탐색 및 설정에 활용될 수 있는 키트 및 그것의제조방법 |
| CA2688174C (en) * | 2008-12-19 | 2018-08-07 | F. Hoffmann-La Roche Ag | Dry composition of reaction compounds with stabilized polymerase |
| JP5608997B2 (ja) * | 2009-03-31 | 2014-10-22 | 東洋紡株式会社 | 保存安定性に優れた核酸増幅検出試薬キット |
| EP2440658B1 (de) | 2009-06-12 | 2014-10-08 | Micronics, Inc. | Rehydratisierbare matrizen für trockenlagerung von taq-polymerase in einer mikrofluidischen vorrichtung |
| CN102803507B (zh) | 2009-06-12 | 2016-05-25 | 精密公司 | 用于微流体装置中在板反应剂的脱水储存的组合物及方法 |
| ES2527684T3 (es) * | 2009-08-01 | 2015-01-28 | F.Hoffmann-La Roche Ag | Detección mejorada de contaminación bacteriana (mollicutes) |
| FI20096013A7 (fi) | 2009-10-02 | 2011-04-03 | Finnzymes Oy | Menetelmä reaktioseoksen valmistelemiseksi ja tähän liittyvät tuotteet |
| US12065698B2 (en) | 2009-10-02 | 2024-08-20 | Thermo Fisher Scientific Baltics Uab | Sample processing apparatus and method |
| GB201008125D0 (en) * | 2010-05-14 | 2010-06-30 | Biofortuna Ltd | Tissue typing assays and kits |
| WO2012018638A2 (en) | 2010-07-26 | 2012-02-09 | Biomatrica, Inc. | Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures |
| EP2598661B1 (de) | 2010-07-26 | 2017-09-27 | Biomatrica, INC. | Zusammensetzungen zur stabilisierung von dna, rna und proteinen in speichel- und anderen biologischen proben während des transports und der lagerung bei umgebungstemperaturen |
| KR101939336B1 (ko) | 2011-02-18 | 2019-01-16 | 주식회사 엘지화학 | 호흡기 바이러스 검출용 조성물 및 이를 포함하는 호흡기 바이러스 검출용 키트 |
| JP2013005796A (ja) * | 2011-05-26 | 2013-01-10 | Arkray Inc | 乾燥試薬、乾燥試薬キット、試薬器、乾燥試薬の製造方法 |
| EP2806890A4 (de) | 2012-01-26 | 2015-09-02 | Longhorn Vaccines & Diagnostics Llc | Zusammengesetzte antigensequenzen und impfstoffe |
| BR112014019168B1 (pt) | 2012-02-03 | 2021-10-05 | California Institute Of Technology | Método capaz de detectar de forma não degenerada presença ou ausência de analitos em um único volume de amostra e método de detecção da presença ou ausência de cada analito dentre uma pluralidade de analitos |
| WO2014007289A1 (ja) * | 2012-07-05 | 2014-01-09 | 日本碍子株式会社 | 核酸クロマトグラフィー法、核酸クロマトグラフィー用組成物及びこれを含むキット |
| CN104662172B (zh) | 2012-08-03 | 2018-07-06 | 加州理工学院 | Pcr中具有减少的硬件和要求的多重化和定量 |
| EP2934572A4 (de) | 2012-12-20 | 2016-11-23 | Biomatrica Inc | Formulierungen und verfahren zur stabilisierung von pcr-reagenzien |
| US20150346097A1 (en) | 2012-12-21 | 2015-12-03 | Micronics, Inc. | Portable fluorescence detection system and microassay cartridge |
| KR20150096788A (ko) | 2012-12-21 | 2015-08-25 | 마이크로닉스 인코포레이티드. | 마이크로 유체공학 용도를 위한 저탄성 막 |
| WO2014182847A1 (en) | 2013-05-07 | 2014-11-13 | Micronics, Inc. | Device for preparation and analysis of nucleic acids |
| WO2014182844A1 (en) | 2013-05-07 | 2014-11-13 | Micronics, Inc. | Microfluidic devices and methods for performing serum separation and blood cross-matching |
| JP6661554B2 (ja) | 2014-06-10 | 2020-03-11 | バイオマトリカ,インク. | 周囲温度における血小板の安定化 |
| CA2985652C (en) | 2015-05-14 | 2020-03-10 | Gerald W. FISHER | Rapid methods for the extraction of nucleic acids from biological samples |
| TW201703754A (zh) * | 2015-05-25 | 2017-02-01 | 卡尤迪生物科技(北京)有限公司 | 用於樣品收集的裝置和方法 |
| WO2016187780A1 (en) * | 2015-05-25 | 2016-12-01 | Coyote Bioscience Yixing Co., Ltd. | Device and method for sample collection |
| JP6827048B2 (ja) | 2015-12-08 | 2021-02-10 | バイオマトリカ,インク. | 赤血球沈降速度の低下 |
| US20180363026A1 (en) * | 2015-12-08 | 2018-12-20 | Biomatrica, Inc. | Stabilization of pcr reagents and assays |
| US10066263B2 (en) | 2016-06-17 | 2018-09-04 | California Institute Of Technology | Nucleic acid reactions and related methods and compositions |
| US10793901B2 (en) | 2016-12-28 | 2020-10-06 | Roche Molecular Systems, Inc. | Reversibly protected nucleotide reagents with high thermal stability |
| CN112424377A (zh) | 2018-04-17 | 2021-02-26 | 克罗玛科德公司 | 用于多重分析的方法和系统 |
| US12203129B2 (en) | 2018-07-03 | 2025-01-21 | ChromaCode, Inc. | Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays |
| JP7418717B2 (ja) | 2019-06-07 | 2024-01-22 | 国立大学法人 東京医科歯科大学 | 微生物の検出方法 |
| US12485166B2 (en) | 2020-02-06 | 2025-12-02 | Longhorn Vaccines And Diagnostics, Llc | Vaccines for the treatment and prevention of zoonotic infections |
| WO2022087122A1 (en) | 2020-10-20 | 2022-04-28 | Longhorn Vaccines And Diagnostics, Llc | Immunogenic antigens |
| JP2022153338A (ja) * | 2021-03-29 | 2022-10-12 | 東洋紡株式会社 | 核酸増幅用組成物の保存安定性の向上方法 |
| CN113736919A (zh) * | 2021-09-14 | 2021-12-03 | 武汉明德生物科技股份有限公司 | 一种核酸检测试剂盒及其使用方法 |
| KR102454254B1 (ko) * | 2021-12-23 | 2022-10-14 | 주식회사 에스엠엘제니트리 | 다당류에 단백질이 포합된 폴리머, 그 제조 방법, 이를 포함하는 효소 안정화 조성물 및 이를 이용한 표적 핵산 분자 검출 방법 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6035263A (ja) * | 1983-08-05 | 1985-02-23 | Wako Pure Chem Ind Ltd | 不溶性担体に固定化された免疫活性物質の安定化法及び該物質を構成単位として含む生理活性物質測定用試薬 |
| WO1987000196A1 (en) * | 1985-07-09 | 1987-01-15 | Quadrant Bioresources Limited | Protection of proteins and the like |
| US5310652A (en) * | 1986-08-22 | 1994-05-10 | Hoffman-La Roche Inc. | Reverse transcription with thermostable DNA polymerase-high temperature reverse transcription |
| US6127155A (en) * | 1986-08-22 | 2000-10-03 | Roche Molecular Systems, Inc. | Stabilized thermostable nucleic acid polymerase compositions containing non-ionic polymeric detergents |
| WO1994016107A1 (en) * | 1993-01-12 | 1994-07-21 | Thomas Jefferson University | DNA SEQUENCING WITH Bst POLYMERASE |
| US5955448A (en) * | 1994-08-19 | 1999-09-21 | Quadrant Holdings Cambridge Limited | Method for stabilization of biological substances during drying and subsequent storage and compositions thereof |
| US5876992A (en) * | 1996-07-03 | 1999-03-02 | Molecular Biology Resources, Inc. | Method and formulation for stabilization of enzymes |
| US5861251A (en) * | 1996-10-15 | 1999-01-19 | Bioneer Corporation | Lyophilized reagent for polymerase chain reaction |
| US6242235B1 (en) * | 1998-06-24 | 2001-06-05 | Promega Corp. | Polymerase stabilization by polyethoxylated amine surfactants |
| US6153412A (en) * | 1998-12-07 | 2000-11-28 | Bioneer Corporation | Lyophilized reagent for polymerase chain reaction |
| GB9920194D0 (en) * | 1999-08-27 | 1999-10-27 | Advanced Biotech Ltd | A heat-stable thermostable DNA polymerase for use in nucleic acid amplification |
| WO2001092569A2 (en) * | 2000-05-31 | 2001-12-06 | Tepnel Medical Limited | Formulation for polymerase chain reaction and vessel containing same |
| ES2180416B1 (es) * | 2001-03-12 | 2004-06-01 | BIOTOOLS BIOTECHNOLOGICAL & MEDICAL LABORATORIES, S.A. | Procedimiento para la preparacion de mezclas de reaccion estabilizadas, total o parcialmente desecadas, que comprenden, al menos, una enzima, mezclas de reaccion y kits que las contienen. |
| US20020173016A1 (en) * | 2001-03-27 | 2002-11-21 | Helmut Wurst | High-throughput nucleic acid polymerase devices and methods for their use |
| US20030149259A1 (en) * | 2001-05-18 | 2003-08-07 | Callahan Johnny Dale | Foot and mouth disease virus diagnostic and methods |
| EP1421200B1 (de) * | 2001-08-23 | 2006-12-13 | Merck & Co., Inc. | Multiplex-hpv-pcr-fluoreszenzassays unter verwendung mehrerer fluorophore |
| US7407747B2 (en) * | 2002-10-15 | 2008-08-05 | Applera Corporation | Method for drying dye-terminator sequencing reagents |
| FI20040768A0 (fi) * | 2004-06-04 | 2004-06-04 | Teemu Korpimaeki | Menetelmä määritysreagenssien stabiloimiseksi, stabilisoituja määritysreagensseja sisältävä reagenssisäiliö ja sen käyttö |
-
2007
- 2007-05-23 WO PCT/US2007/069566 patent/WO2007137291A1/en not_active Ceased
- 2007-05-23 EP EP10001187A patent/EP2210955A3/de not_active Withdrawn
- 2007-05-23 CA CA002653454A patent/CA2653454A1/en not_active Abandoned
- 2007-05-23 US US11/752,760 patent/US20080050737A1/en not_active Abandoned
- 2007-05-23 JP JP2009512287A patent/JP2009538146A/ja active Pending
- 2007-05-23 EP EP07762310A patent/EP2021508B1/de not_active Revoked
- 2007-05-23 AT AT07762310T patent/ATE555216T1/de active
-
2010
- 2010-01-26 US US12/694,196 patent/US20100196904A1/en not_active Abandoned
-
2012
- 2012-10-11 US US13/649,725 patent/US20130273531A1/en not_active Abandoned
-
2013
- 2013-08-15 JP JP2013168845A patent/JP2013240357A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013240357A (ja) | 2013-12-05 |
| CA2653454A1 (en) | 2007-11-29 |
| EP2210955A3 (de) | 2010-09-15 |
| US20100196904A1 (en) | 2010-08-05 |
| WO2007137291A1 (en) | 2007-11-29 |
| EP2021508A4 (de) | 2009-09-30 |
| US20130273531A1 (en) | 2013-10-17 |
| EP2021508B1 (de) | 2012-04-25 |
| EP2210955A2 (de) | 2010-07-28 |
| US20080050737A1 (en) | 2008-02-28 |
| EP2021508A1 (de) | 2009-02-11 |
| JP2009538146A (ja) | 2009-11-05 |
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