ATE64306T1 - Mittel zur erhoehung der transdermalen permeation. - Google Patents

Mittel zur erhoehung der transdermalen permeation.

Info

Publication number
ATE64306T1
ATE64306T1 AT87309459T AT87309459T ATE64306T1 AT E64306 T1 ATE64306 T1 AT E64306T1 AT 87309459 T AT87309459 T AT 87309459T AT 87309459 T AT87309459 T AT 87309459T AT E64306 T1 ATE64306 T1 AT E64306T1
Authority
AT
Austria
Prior art keywords
human
agent
transdermal administration
lower animal
transdermal permeation
Prior art date
Application number
AT87309459T
Other languages
English (en)
Inventor
Michael Lee Francoeur
Russell Owen Potts
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE64306T1 publication Critical patent/ATE64306T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT87309459T 1986-10-31 1987-10-27 Mittel zur erhoehung der transdermalen permeation. ATE64306T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92564186A 1986-10-31 1986-10-31
EP87309459A EP0271983B1 (de) 1986-10-31 1987-10-27 Mittel zur Erhöhung der transdermalen Permeation

Publications (1)

Publication Number Publication Date
ATE64306T1 true ATE64306T1 (de) 1991-06-15

Family

ID=25452022

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87309459T ATE64306T1 (de) 1986-10-31 1987-10-27 Mittel zur erhoehung der transdermalen permeation.

Country Status (24)

Country Link
EP (1) EP0271983B1 (de)
JP (1) JPH0757725B2 (de)
KR (1) KR900003697B1 (de)
CN (1) CN87107548A (de)
AT (1) ATE64306T1 (de)
AU (1) AU595948B2 (de)
CA (1) CA1338008C (de)
DE (1) DE3770786D1 (de)
DK (1) DK568187A (de)
EG (1) EG18324A (de)
ES (1) ES2031518T3 (de)
GR (1) GR3002137T3 (de)
HU (1) HU197993B (de)
IE (1) IE60379B1 (de)
IL (1) IL84269A (de)
MX (1) MX171058B (de)
MY (1) MY102980A (de)
NO (1) NO175617C (de)
NZ (1) NZ222346A (de)
PH (1) PH25498A (de)
PT (1) PT86023B (de)
RU (2) RU1836078C (de)
YU (1) YU46755B (de)
ZA (1) ZA878161B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196416A (en) * 1987-08-28 1993-03-23 Eli Lilly And Company Transdermal flux-enhancing pharmaceutical compositions comprising azone, ethanol and water
ZA886218B (en) * 1987-08-28 1990-04-25 Lilly Co Eli Permeation enhancement compositions
ATE80313T1 (de) * 1988-02-29 1992-09-15 Pfizer Mittel zur erhoehung des transdermalen penetrationsflusses.
CH679119A5 (de) * 1988-05-13 1991-12-31 Sandoz Ag
US5024843A (en) * 1989-09-05 1991-06-18 Alza Corporation Oral hypoglycemic glipizide granulation
US5023085A (en) * 1989-11-29 1991-06-11 Pfizer Inc. Transdermal flux enhancers in combination with iontophoresis in topical administration of pharmaceuticals
US5149719A (en) * 1990-04-27 1992-09-22 Minnesota Mining And Manufacturing Company Composition for transdermal penetration of medicaments
WO1992017185A1 (en) * 1991-03-29 1992-10-15 University Of Florida Targeted drug delivery via mixed phosphate derivatives
ES2160623T3 (es) * 1992-12-31 2001-11-16 Sunkyong Ind Ltd Composiciones farmaceuticas mejoradas para la penetracion en la piel de piroxicam.
DE4341572C1 (de) * 1993-12-07 1995-06-22 Univ Dresden Tech Zahnriemengetriebe
TW304167B (de) * 1995-01-30 1997-05-01 Lilly Co Eli
GB2306885B (en) * 1995-11-08 1999-07-14 Reckitt & Colmann Prod Ltd Supersaturated Pharmaceutical Compositions
EP0849265A1 (de) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Neue polymorphe Form von Doxazosin-Mesylat (Form II)
JP2000143540A (ja) * 1998-11-06 2000-05-23 Bristol Myers Squibb Co 非ステロイド系消炎鎮痛薬含有外用剤
US7198801B2 (en) 2000-08-03 2007-04-03 Antares Pharma Ipl Ag Formulations for transdermal or transmucosal application
ATE485837T1 (de) 2000-08-03 2010-11-15 Antares Pharma Ipl Ag Zusammensetzung zur transdermalen und/oder transmukosalen verabreichung von wirkstoffen, die ausreichende therapeutische spiegel garantiert
US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
RU2229286C2 (ru) * 2002-05-27 2004-05-27 Пятигорская государственная фармацевтическая академия Мазь ибупрофена, приготовленная на полиэтиленоксидной основе, обладающая противовоспалительным действием
RU2261086C2 (ru) * 2003-05-26 2005-09-27 Горский государственный аграрный университет (ГГАУ) Лечебная мазь для животных
JP4626202B2 (ja) * 2003-07-16 2011-02-02 大正製薬株式会社 ピロキシカム含有外用消炎鎮痛剤組成物
ATE534373T1 (de) 2003-10-10 2011-12-15 Antares Pharma Ipl Ag Transdermale pharmazeutische formulierung zur minimierung von rückständen auf der haut
US7425340B2 (en) 2004-05-07 2008-09-16 Antares Pharma Ipl Ag Permeation enhancing compositions for anticholinergic agents
US8067399B2 (en) 2005-05-27 2011-11-29 Antares Pharma Ipl Ag Method and apparatus for transdermal or transmucosal application of testosterone
CN102225046A (zh) * 2005-08-05 2011-10-26 努沃研究公司 透皮释药剂型
GEP20125432B (en) 2005-10-12 2012-03-26 Unimed Pharmaceuticals Llc Improved testosterone gel and use thereof
FR2892410B1 (fr) * 2005-10-21 2010-10-15 Fabre Pierre Dermo Cosmetique Nouveaux hydro-acides gras insatures et leur utilisation dermo cosmetologique
CN101426475A (zh) 2006-04-21 2009-05-06 安塔雷斯制药Ipl股份公司 使用用于经皮或经粘膜应用的制剂治疗热潮红的方法
CN102256604A (zh) * 2008-12-17 2011-11-23 株式会社医药处方 稳定的氨氯地平含水口服制剂
US20130123221A1 (en) * 2011-05-16 2013-05-16 Dale L. Pearlman Compositions and methods for the treatment of skin diseases
US8580286B2 (en) 2012-03-16 2013-11-12 Dale L. Pearlman Compositions and methods for the treatment of skin diseases
JP7515582B2 (ja) 2019-11-06 2024-07-12 スマーテック トピカル，インコーポレイテッド シクロオキシゲナーゼ阻害剤の局所配合剤およびその使用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
US4316893A (en) * 1975-06-19 1982-02-23 Nelson Research & Development Co. Vehicle composition containing 1-substituted azacycloalkan-2-ones
US4405616A (en) * 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
BE843140A (fr) * 1975-06-19 1976-10-18 Aazacycloalcan-2-ones 1-substituees et compositions pharmaceutiques contenant ces composes a titre d'excipients
EP0127426A1 (de) * 1983-05-23 1984-12-05 Takeda Chemical Industries, Ltd. Perkutane pharmazeutische Zusammensetzungen zur äusserlichen Anwendung
DK243084A (da) * 1983-05-26 1984-11-27 Takeda Chemical Industries Ltd Perkutane farmaceutiske praeparater til udvortes brug
US4537776A (en) * 1983-06-21 1985-08-27 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
US4557934A (en) * 1983-06-21 1985-12-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one

Also Published As

Publication number Publication date
IL84269A (en) 1991-08-16
PT86023A (en) 1987-11-01
YU196487A (sh) 1993-05-28
EG18324A (en) 1992-09-30
ES2031518T3 (es) 1992-12-16
NO874531L (no) 1988-05-02
CA1338008C (en) 1996-01-30
PT86023B (pt) 1990-07-31
EP0271983B1 (de) 1991-06-12
ZA878161B (en) 1989-06-28
NO874531D0 (no) 1987-10-30
NZ222346A (en) 1990-08-28
RU1836078C (ru) 1993-08-23
DK568187A (da) 1988-05-01
KR880004823A (ko) 1988-06-27
YU46755B (sh) 1994-05-10
JPH0757725B2 (ja) 1995-06-21
HUT45403A (en) 1988-07-28
AU595948B2 (en) 1990-04-12
IE872896L (en) 1988-04-30
IL84269A0 (en) 1988-03-31
IE60379B1 (en) 1994-07-13
JPS63122631A (ja) 1988-05-26
GR3002137T3 (en) 1992-12-30
DE3770786D1 (de) 1991-07-18
HU197993B (en) 1989-07-28
MY102980A (en) 1993-03-31
NO175617B (de) 1994-08-01
RU2107515C1 (ru) 1998-03-27
PH25498A (en) 1991-07-24
CN87107548A (zh) 1988-05-11
AU8054287A (en) 1988-05-05
KR900003697B1 (ko) 1990-05-30
NO175617C (no) 1994-11-09
MX171058B (es) 1993-09-27
EP0271983A1 (de) 1988-06-22
DK568187D0 (da) 1987-10-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee