EG18324A - Transdermal flux enhancing compositions - Google Patents

Transdermal flux enhancing compositions

Info

Publication number: EG18324A
Authority: EG; Egypt
Prior art keywords: flux enhancing; human; transdermal flux; transdermal; enhancing compositions
Prior art date: 1986-10-31

Application number

EG618/87A

Other languages

English (en)

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-10-31

Filing date

1987-10-29

Publication date

1992-09-30

1987-10-29 Application filed by Pfizer filed Critical Pfizer

1992-09-30 Application granted granted Critical

1992-09-30 Publication of EG18324A publication Critical patent/EG18324A/xx

Links

230000002708 enhancing effect Effects 0.000 title abstract 2
230000004907 flux Effects 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 4
241001465754 Metazoa Species 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
XXJGBENTLXFVFI-UHFFFAOYSA-N 1-amino-methylene Chemical compound N[CH2] XXJGBENTLXFVFI-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
239000003961 penetration enhancing agent Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000651 prodrug Substances 0.000 abstract 1
229940002612 prodrug Drugs 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Oil, Petroleum & Natural Gas (AREA)
Dermatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Materials For Medical Uses (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

EG618/87A 1986-10-31 1987-10-29 Transdermal flux enhancing compositions EG18324A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US92564186A	1986-10-31	1986-10-31

Publications (1)

Publication Number	Publication Date
EG18324A true EG18324A (en)	1992-09-30

Family

ID=25452022

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG618/87A EG18324A (en)	1986-10-31	1987-10-29	Transdermal flux enhancing compositions

Country Status (24)

Country	Link
EP (1)	EP0271983B1 (de)
JP (1)	JPH0757725B2 (de)
KR (1)	KR900003697B1 (de)
CN (1)	CN87107548A (de)
AT (1)	ATE64306T1 (de)
AU (1)	AU595948B2 (de)
CA (1)	CA1338008C (de)
DE (1)	DE3770786D1 (de)
DK (1)	DK568187A (de)
EG (1)	EG18324A (de)
ES (1)	ES2031518T3 (de)
GR (1)	GR3002137T3 (de)
HU (1)	HU197993B (de)
IE (1)	IE60379B1 (de)
IL (1)	IL84269A (de)
MX (1)	MX171058B (de)
MY (1)	MY102980A (de)
NO (1)	NO175617C (de)
NZ (1)	NZ222346A (de)
PH (1)	PH25498A (de)
PT (1)	PT86023B (de)
RU (2)	RU1836078C (de)
YU (1)	YU46755B (de)
ZA (1)	ZA878161B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5196416A (en) *	1987-08-28	1993-03-23	Eli Lilly And Company	Transdermal flux-enhancing pharmaceutical compositions comprising azone, ethanol and water
ZA886218B (en) *	1987-08-28	1990-04-25	Lilly Co Eli	Permeation enhancement compositions
ATE80313T1 (de) *	1988-02-29	1992-09-15	Pfizer	Mittel zur erhoehung des transdermalen penetrationsflusses.
CH679119A5 (de) *	1988-05-13	1991-12-31	Sandoz Ag
US5024843A (en) *	1989-09-05	1991-06-18	Alza Corporation	Oral hypoglycemic glipizide granulation
US5023085A (en) *	1989-11-29	1991-06-11	Pfizer Inc.	Transdermal flux enhancers in combination with iontophoresis in topical administration of pharmaceuticals
US5149719A (en) *	1990-04-27	1992-09-22	Minnesota Mining And Manufacturing Company	Composition for transdermal penetration of medicaments
WO1992017185A1 (en) *	1991-03-29	1992-10-15	University Of Florida	Targeted drug delivery via mixed phosphate derivatives
ES2160623T3 (es) *	1992-12-31	2001-11-16	Sunkyong Ind Ltd	Composiciones farmaceuticas mejoradas para la penetracion en la piel de piroxicam.
DE4341572C1 (de) *	1993-12-07	1995-06-22	Univ Dresden Tech	Zahnriemengetriebe
TW304167B (de) *	1995-01-30	1997-05-01	Lilly Co Eli
GB2306885B (en) *	1995-11-08	1999-07-14	Reckitt & Colmann Prod Ltd	Supersaturated Pharmaceutical Compositions
EP0849265A1 (de) *	1996-12-20	1998-06-24	HEUMANN PHARMA GmbH	Neue polymorphe Form von Doxazosin-Mesylat (Form II)
JP2000143540A (ja) *	1998-11-06	2000-05-23	Bristol Myers Squibb Co	非ステロイド系消炎鎮痛薬含有外用剤
US7198801B2 (en)	2000-08-03	2007-04-03	Antares Pharma Ipl Ag	Formulations for transdermal or transmucosal application
ATE485837T1 (de)	2000-08-03	2010-11-15	Antares Pharma Ipl Ag	Zusammensetzung zur transdermalen und/oder transmukosalen verabreichung von wirkstoffen, die ausreichende therapeutische spiegel garantiert
US8980290B2 (en)	2000-08-03	2015-03-17	Antares Pharma Ipl Ag	Transdermal compositions for anticholinergic agents
US6503894B1 (en)	2000-08-30	2003-01-07	Unimed Pharmaceuticals, Inc.	Pharmaceutical composition and method for treating hypogonadism
RU2229286C2 (ru) *	2002-05-27	2004-05-27	Пятигорская государственная фармацевтическая академия	Мазь ибупрофена, приготовленная на полиэтиленоксидной основе, обладающая противовоспалительным действием
RU2261086C2 (ru) *	2003-05-26	2005-09-27	Горский государственный аграрный университет (ГГАУ)	Лечебная мазь для животных
JP4626202B2 (ja) *	2003-07-16	2011-02-02	大正製薬株式会社	ピロキシカム含有外用消炎鎮痛剤組成物
ATE534373T1 (de)	2003-10-10	2011-12-15	Antares Pharma Ipl Ag	Transdermale pharmazeutische formulierung zur minimierung von rückständen auf der haut
US7425340B2 (en)	2004-05-07	2008-09-16	Antares Pharma Ipl Ag	Permeation enhancing compositions for anticholinergic agents
US8067399B2 (en)	2005-05-27	2011-11-29	Antares Pharma Ipl Ag	Method and apparatus for transdermal or transmucosal application of testosterone
CN102225046A (zh) *	2005-08-05	2011-10-26	努沃研究公司	透皮释药剂型
GEP20125432B (en)	2005-10-12	2012-03-26	Unimed Pharmaceuticals Llc	Improved testosterone gel and use thereof
FR2892410B1 (fr) *	2005-10-21	2010-10-15	Fabre Pierre Dermo Cosmetique	Nouveaux hydro-acides gras insatures et leur utilisation dermo cosmetologique
CN101426475A (zh)	2006-04-21	2009-05-06	安塔雷斯制药Ipl股份公司	使用用于经皮或经粘膜应用的制剂治疗热潮红的方法
CN102256604A (zh) *	2008-12-17	2011-11-23	株式会社医药处方	稳定的氨氯地平含水口服制剂
US20130123221A1 (en) *	2011-05-16	2013-05-16	Dale L. Pearlman	Compositions and methods for the treatment of skin diseases
US8580286B2 (en)	2012-03-16	2013-11-12	Dale L. Pearlman	Compositions and methods for the treatment of skin diseases
JP7515582B2 (ja)	2019-11-06	2024-07-12	スマーテックトピカル，インコーポレイテッド	シクロオキシゲナーゼ阻害剤の局所配合剤およびその使用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1538903A (en) *	1975-04-11	1979-01-24	Nelson Res & Dev	Carrier for a topically applied physiologically active agent or cosmetic agent
US4316893A (en) *	1975-06-19	1982-02-23	Nelson Research & Development Co.	Vehicle composition containing 1-substituted azacycloalkan-2-ones
US4405616A (en) *	1975-06-19	1983-09-20	Nelson Research & Development Company	Penetration enhancers for transdermal drug delivery of systemic agents
BE843140A (fr) *	1975-06-19	1976-10-18		Aazacycloalcan-2-ones 1-substituees et compositions pharmaceutiques contenant ces composes a titre d'excipients
EP0127426A1 (de) *	1983-05-23	1984-12-05	Takeda Chemical Industries, Ltd.	Perkutane pharmazeutische Zusammensetzungen zur äusserlichen Anwendung
DK243084A (da) *	1983-05-26	1984-11-27	Takeda Chemical Industries Ltd	Perkutane farmaceutiske praeparater til udvortes brug
US4537776A (en) *	1983-06-21	1985-08-27	The Procter & Gamble Company	Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
US4557934A (en) *	1983-06-21	1985-12-10	The Procter & Gamble Company	Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one

1987
- 1987-10-17 MY MYPI87002939A patent/MY102980A/en unknown
- 1987-10-25 IL IL84269A patent/IL84269A/xx not_active IP Right Cessation
- 1987-10-27 AT AT87309459T patent/ATE64306T1/de not_active IP Right Cessation
- 1987-10-27 ES ES198787309459T patent/ES2031518T3/es not_active Expired - Lifetime
- 1987-10-27 DE DE8787309459T patent/DE3770786D1/de not_active Expired - Lifetime
- 1987-10-27 EP EP87309459A patent/EP0271983B1/de not_active Expired - Lifetime
- 1987-10-28 YU YU196487A patent/YU46755B/sh unknown
- 1987-10-28 IE IE289687A patent/IE60379B1/en not_active IP Right Cessation
- 1987-10-29 PH PH36001A patent/PH25498A/en unknown
- 1987-10-29 PT PT86023A patent/PT86023B/pt not_active IP Right Cessation
- 1987-10-29 CA CA000550540A patent/CA1338008C/en not_active Expired - Fee Related
- 1987-10-29 EG EG618/87A patent/EG18324A/xx active
- 1987-10-29 CN CN198787107548A patent/CN87107548A/zh active Pending
- 1987-10-29 NZ NZ222346A patent/NZ222346A/xx unknown
- 1987-10-30 RU SU874203579A patent/RU1836078C/ru active
- 1987-10-30 HU HU874898A patent/HU197993B/hu not_active IP Right Cessation
- 1987-10-30 DK DK568187A patent/DK568187A/da not_active Application Discontinuation
- 1987-10-30 AU AU80542/87A patent/AU595948B2/en not_active Ceased
- 1987-10-30 JP JP62275581A patent/JPH0757725B2/ja not_active Expired - Lifetime
- 1987-10-30 ZA ZA878161A patent/ZA878161B/xx unknown
- 1987-10-30 MX MX026963A patent/MX171058B/es unknown
- 1987-10-30 NO NO874531A patent/NO175617C/no unknown
- 1987-10-30 KR KR1019870012096A patent/KR900003697B1/ko not_active Expired
1991
- 1991-06-13 GR GR91400807T patent/GR3002137T3/el unknown
- 1991-12-23 RU SU5010466A patent/RU2107515C1/ru active

Also Published As

Publication number	Publication date
IL84269A (en)	1991-08-16
PT86023A (en)	1987-11-01
YU196487A (sh)	1993-05-28
ES2031518T3 (es)	1992-12-16
NO874531L (no)	1988-05-02
ATE64306T1 (de)	1991-06-15
CA1338008C (en)	1996-01-30
PT86023B (pt)	1990-07-31
EP0271983B1 (de)	1991-06-12
ZA878161B (en)	1989-06-28
NO874531D0 (no)	1987-10-30
NZ222346A (en)	1990-08-28
RU1836078C (ru)	1993-08-23
DK568187A (da)	1988-05-01
KR880004823A (ko)	1988-06-27
YU46755B (sh)	1994-05-10
JPH0757725B2 (ja)	1995-06-21
HUT45403A (en)	1988-07-28
AU595948B2 (en)	1990-04-12
IE872896L (en)	1988-04-30
IL84269A0 (en)	1988-03-31
IE60379B1 (en)	1994-07-13
JPS63122631A (ja)	1988-05-26
GR3002137T3 (en)	1992-12-30
DE3770786D1 (de)	1991-07-18
HU197993B (en)	1989-07-28
MY102980A (en)	1993-03-31
NO175617B (de)	1994-08-01
RU2107515C1 (ru)	1998-03-27
PH25498A (en)	1991-07-24
CN87107548A (zh)	1988-05-11
AU8054287A (en)	1988-05-05
KR900003697B1 (ko)	1990-05-30
NO175617C (no)	1994-11-09
MX171058B (es)	1993-09-27
EP0271983A1 (de)	1988-06-22
DK568187D0 (da)	1987-10-30

Publication	Publication Date	Title
EG18324A (en)	1992-09-30	Transdermal flux enhancing compositions
EP0331382A3 (en)	1990-05-30	Transdermal flux enhancing compositions
IS1262B6 (is)	1987-03-27	Ný samsetning efnis
ATE41772T1 (de)	1989-04-15	Polymethoxybenzyl-piperazin-derivate, verfahren zu ihrer herstellung und diese derivate enthaltende pharmazeutische zusammensetzungen.
DK259387A (da)	1987-11-22	Steroide forbindelser, der er virksomme mod kraeft og obesitet
KR830009776A (ko)	1983-12-23	세포 보호 유도방법
KR920011486A (ko)	1992-07-24	항종양제
JPS54125663A (en)	1979-09-29	Carcinostatic agent and novel compound having carcinostatic activity
JPH04128220A (ja)	1992-04-28	抗ヘルペスウイルス剤