ATE67201T1 - Verfahren zur herstellung von 9-(hydroxy-alkyl) hypoxanthinen. - Google Patents
Verfahren zur herstellung von 9-(hydroxy-alkyl) hypoxanthinen.Info
- Publication number
- ATE67201T1 ATE67201T1 AT88901029T AT88901029T ATE67201T1 AT E67201 T1 ATE67201 T1 AT E67201T1 AT 88901029 T AT88901029 T AT 88901029T AT 88901029 T AT88901029 T AT 88901029T AT E67201 T1 ATE67201 T1 AT E67201T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- hypoxanthins
- hydroxy
- production
- branched
- Prior art date
Links
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/28—Oxygen atom
- C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8719083A IT1215339B (it) | 1987-01-14 | 1987-01-14 | Procedimento per la preparazione di 9-(idrossialchil)-ipoxantine |
| PCT/EP1988/000001 WO1988005437A1 (en) | 1987-01-14 | 1988-01-04 | A process for the preparation of 9-(hydroxyalkyl)-hypoxanthines |
| EP88901029A EP0355085B1 (de) | 1987-01-14 | 1988-01-04 | Verfahren zur herstellung von 9-(hydroxy-alkyl) hypoxanthinen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE67201T1 true ATE67201T1 (de) | 1991-09-15 |
Family
ID=11154399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88901029T ATE67201T1 (de) | 1987-01-14 | 1988-01-04 | Verfahren zur herstellung von 9-(hydroxy-alkyl) hypoxanthinen. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0355085B1 (de) |
| JP (1) | JPH0813817B2 (de) |
| AT (1) | ATE67201T1 (de) |
| AU (1) | AU605837B2 (de) |
| DE (1) | DE3864820D1 (de) |
| IT (1) | IT1215339B (de) |
| WO (1) | WO1988005437A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62208295A (ja) * | 1986-03-07 | 1987-09-12 | Nippon Kayaku Co Ltd | ヒポキサンチン塩基を有する新規化合物およびその製造法 |
| US6110923A (en) * | 1994-06-22 | 2000-08-29 | Biochem Pharma Inc. | Method for treating cancer using novel substituted purinyl derivatives with immunomodulating activity |
| BRPI0621509A2 (pt) * | 2006-03-15 | 2011-12-13 | Csir | modulação da atividade de fosforil transferase de glutamina sintetase |
| GB2451594A (en) * | 2006-03-15 | 2009-02-04 | Csir | Modulation of phosphoryl transferase activity of glutamine synthetase |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4221909A (en) * | 1978-09-15 | 1980-09-09 | Sloan-Kettering Institute For Cancer Research | P-Acetamidobenzoic acid salts of 9-(hydroxyalkyl) purines |
| US4221910A (en) * | 1978-09-15 | 1980-09-09 | Newport Pharmaceuticals International, Inc. | 9-(Hydroxy alkyl)purines |
| JP2793825B2 (ja) * | 1988-01-20 | 1998-09-03 | リージヤンツ・オブ・ザ・ユニバーシテイ・オブ・ミネソタ | ジデオキシジデヒドロ炭素環式ヌクレオシド |
-
1987
- 1987-01-14 IT IT8719083A patent/IT1215339B/it active
-
1988
- 1988-01-04 EP EP88901029A patent/EP0355085B1/de not_active Expired - Lifetime
- 1988-01-04 DE DE8888901029T patent/DE3864820D1/de not_active Expired - Lifetime
- 1988-01-04 AT AT88901029T patent/ATE67201T1/de not_active IP Right Cessation
- 1988-01-04 JP JP63501289A patent/JPH0813817B2/ja not_active Expired - Lifetime
- 1988-01-04 WO PCT/EP1988/000001 patent/WO1988005437A1/en not_active Ceased
- 1988-01-04 AU AU12265/88A patent/AU605837B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPH02501924A (ja) | 1990-06-28 |
| AU1226588A (en) | 1988-08-10 |
| IT1215339B (it) | 1990-02-08 |
| EP0355085B1 (de) | 1991-09-11 |
| WO1988005437A1 (en) | 1988-07-28 |
| DE3864820D1 (de) | 1991-10-17 |
| JPH0813817B2 (ja) | 1996-02-14 |
| AU605837B2 (en) | 1991-01-24 |
| IT8719083A0 (it) | 1987-01-14 |
| EP0355085A1 (de) | 1990-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |