ATE67930T1 - Wirkstofftraeger und diesen enthaltende arzneimittel. - Google Patents

Wirkstofftraeger und diesen enthaltende arzneimittel.

Info

Publication number
ATE67930T1
ATE67930T1 AT86104094T AT86104094T ATE67930T1 AT E67930 T1 ATE67930 T1 AT E67930T1 AT 86104094 T AT86104094 T AT 86104094T AT 86104094 T AT86104094 T AT 86104094T AT E67930 T1 ATE67930 T1 AT E67930T1
Authority
AT
Austria
Prior art keywords
carrier
pharmaceutical preparation
pharmaceuticals containing
controlling
gastrointestinal transit
Prior art date
Application number
AT86104094T
Other languages
English (en)
Inventor
Toshinobu Uemura
Toshiaki Ohkuma
Kiyohide Shinooka
Hiroshi Ishikuro
Yoshio Ueda
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of ATE67930T1 publication Critical patent/ATE67930T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
AT86104094T 1985-03-26 1986-03-25 Wirkstofftraeger und diesen enthaltende arzneimittel. ATE67930T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858507779A GB8507779D0 (en) 1985-03-26 1985-03-26 Drug carrier
EP86104094A EP0200902B1 (de) 1985-03-26 1986-03-25 Wirkstoffträger und diesen enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
ATE67930T1 true ATE67930T1 (de) 1991-10-15

Family

ID=10576624

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86104094T ATE67930T1 (de) 1985-03-26 1986-03-25 Wirkstofftraeger und diesen enthaltende arzneimittel.

Country Status (9)

Country Link
US (1) US4690822A (de)
EP (1) EP0200902B1 (de)
JP (1) JPH0772143B2 (de)
AT (1) ATE67930T1 (de)
AU (1) AU590255B2 (de)
CA (1) CA1275045A (de)
DE (1) DE3681755D1 (de)
DK (1) DK136186A (de)
GB (1) GB8507779D0 (de)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755387A (en) * 1985-03-21 1988-07-05 The Procter & Gamble Company Therapeutic particles
DK162986A (da) * 1985-04-12 1986-10-13 Forest Laboratories Terapeutisk middel i enhedsdosisform
US4895724A (en) * 1985-06-07 1990-01-23 Pfizer Inc. Chitosan compositions for controlled and prolonged release of macromolecules
GB8601204D0 (en) * 1986-01-18 1986-02-19 Boots Co Plc Therapeutic agents
IT1191674B (it) * 1986-03-07 1988-03-23 Eurand Spa Formulazioni per la preparazione di farmaci a rilascio prolungato adatte alla somministrazione per via orale
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
JPH0832625B2 (ja) * 1987-01-29 1996-03-29 武田薬品工業株式会社 有核顆粒およびその製造法
NZ230763A (en) * 1988-09-27 1991-10-25 Takeda Chemical Industries Ltd Production of granules having a core by spraying the cores with a dispersion of hydroxypropylcellulose, optionally incorporating an active ingredient
DK166650B1 (da) * 1991-03-15 1993-06-28 Aarhus Oliefabrik As Fedtbaser samt anvendelse af disse i kosmetiske og farmaceutiske emulsionsprodukter
US5498422A (en) * 1991-04-08 1996-03-12 Nippon Shinyaku Company Limited Sustained release capsule
JPH08511559A (ja) * 1993-06-18 1996-12-03 スミスクライン・ビーチャム・コーポレイション 軟外皮ゼラチンに封入された粒子
CA2165789A1 (en) * 1993-06-30 1995-01-12 Takehisa Hata Encapsulated medicine
US5660859A (en) * 1994-12-29 1997-08-26 Mcneil-Ppc, Inc. Gelling agent for polyethylene glycol
NZ280610A (en) * 1994-12-29 1997-08-22 Mcneil Ppc Inc Soft gelatin-like pharmaceutical carrier: gelled polyethylene glycol and dispersed active agent
US6861053B1 (en) * 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
WO1996036330A2 (en) * 1995-05-17 1996-11-21 Cedars-Sinai Medical Center Compositions containing fatty acids for improving digestion and absorption in the small intestine
JPH11505258A (ja) * 1995-05-17 1999-05-18 セダーシナイ メディカル センター 小腸における消化および吸収を改善させる脂肪酸を含む組成物
US7048906B2 (en) 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
US6558708B1 (en) 1995-05-17 2003-05-06 Cedars-Sinai Medical Center Methods for manipulating upper gastrointestinal transit, blood flow, and satiety, and for treating visceral hyperalgesia
WO1997047323A2 (en) * 1996-06-11 1997-12-18 Zonagen, Inc. Chitosan drug delivery system
US6024980A (en) * 1996-06-28 2000-02-15 Mcneil-Ppc, Inc. Multiphase soft gelatin dosage form
US7179486B1 (en) 1997-04-01 2007-02-20 Nostrum Pharmaceuticals, Inc. Process for preparing sustained release tablets
IN186245B (de) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
US6238697B1 (en) 1998-12-21 2001-05-29 Pharmalogix, Inc. Methods and formulations for making bupropion hydrochloride tablets using direct compression
JP2003508420A (ja) 1999-09-02 2003-03-04 ノストラム・ファーマスーティカルズ・インコーポレイテッド 経口投与に適した、制御された放出の経口用量
WO2001058424A1 (en) * 2000-02-09 2001-08-16 West Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited Floating drug delivery composition
FR2814679B1 (fr) * 2000-09-29 2003-04-11 Cll Pharma Compositions pharmaceutiques dispersibles a base de cephalosporines, leur procede de preparation et leur utilisation
US20040022853A1 (en) * 2001-04-26 2004-02-05 Control Delivery Systems, Inc. Polymer-based, sustained release drug delivery system
US20030072731A1 (en) * 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing starch or dextrin
US20030070584A1 (en) 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
US6524618B1 (en) 2001-06-12 2003-02-25 Vijai Kumar Directly compressible extended-release matrix formulation for metformin hydrochloride
IN2014DN10834A (de) * 2001-09-17 2015-09-04 Psivida Inc
US8309118B2 (en) 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
US7429619B2 (en) * 2002-08-02 2008-09-30 Mcneil Consumer Healthcare Polyacrylic film forming compositions
MY148805A (en) * 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
WO2004105505A1 (en) * 2003-05-28 2004-12-09 Unilever N.V. Satiety enhancing food products
ES2337466T3 (es) * 2003-05-28 2010-04-26 Unilever N.V. Productos alimenticios potenciadores de la saciedad.
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
US8075872B2 (en) 2003-08-06 2011-12-13 Gruenenthal Gmbh Abuse-proofed dosage form
DE10336400A1 (de) * 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
DE102004032051A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
TWI301542B (en) * 2005-01-05 2008-10-01 Ind Tech Res Inst Taste sensing mixture and a sensor using the same and a sensory system using the same
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
DE102007011485A1 (de) 2007-03-07 2008-09-11 Grünenthal GmbH Darreichungsform mit erschwertem Missbrauch
CA2713128C (en) 2008-01-25 2016-04-05 Gruenenthal Gmbh Pharmaceutical dosage form
AU2009243681B2 (en) 2008-05-09 2013-12-19 Grunenthal Gmbh Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step
KR101738369B1 (ko) 2009-07-22 2017-05-22 그뤼넨탈 게엠베하 핫 멜트 압출된 제어 방출 투여형
CN102639118B (zh) 2009-07-22 2015-07-29 格吕伦塔尔有限公司 氧化稳定的抗干扰剂型
BR112013005194A2 (pt) 2010-09-02 2016-05-03 Gruenenthal Gmbh forma de dosagem resistente à violação compreendendo sal inorgânico
TWI516286B (zh) 2010-09-02 2016-01-11 歌林達股份有限公司 含陰離子聚合物之抗破碎劑型
BR112014001091A2 (pt) 2011-07-29 2017-02-14 Gruenenthal Gmbh comprimido resistente à adulteração que fornece liberação imediata do fármaco
EA201400172A1 (ru) 2011-07-29 2014-06-30 Грюненталь Гмбх Устойчивая к разрушению таблетка, которая обеспечивает немедленное высвобождение лекарственного средства
US20130143867A1 (en) 2011-12-02 2013-06-06 Sychroneuron Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
MX356421B (es) 2012-02-28 2018-05-29 Gruenenthal Gmbh Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico.
EP2838512B1 (de) 2012-04-18 2018-08-22 Grünenthal GmbH Fälschungssichere und dose dumping sichere pharmazeutische darreichungsform
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
US9737490B2 (en) 2013-05-29 2017-08-22 Grünenthal GmbH Tamper resistant dosage form with bimodal release profile
EP3003279A1 (de) 2013-05-29 2016-04-13 Grünenthal GmbH Manipulationssichere darreichungsform mit einem oder mehreren partikeln
WO2014197744A1 (en) 2013-06-05 2014-12-11 Synchroneuron, Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
BR112016000194A8 (pt) 2013-07-12 2019-12-31 Gruenenthal Gmbh forma de dosagem resistente à violação contendo o polímero de acetato de etileno-vinila
EP3073994A1 (de) 2013-11-26 2016-10-05 Grünenthal GmbH Herstellung einer pulverförmigen pharmazeutischen zusammensetzung mittels kryogenen mahlens
WO2015173195A1 (en) 2014-05-12 2015-11-19 Grünenthal GmbH Tamper resistant immediate release capsule formulation comprising tapentadol
EA201692388A1 (ru) 2014-05-26 2017-05-31 Грюненталь Гмбх Лекарственная форма в виде множества частиц, защищенная от вызываемого этанолом сброса дозы
DE102014119576A1 (de) * 2014-12-23 2016-06-23 Ernst-Moritz-Arndt-Universität Greifswald Pharmazeutische Arzneimittelform zur Applikation auf Schleimhäuten
WO2016170097A1 (en) 2015-04-24 2016-10-27 Grünenthal GmbH Tamper-resistant dosage form with immediate release and resistance against solvent extraction
JP2018526414A (ja) 2015-09-10 2018-09-13 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 乱用抑止性の即放性製剤を用いた経口過剰摂取に対する保護

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126321A (en) * 1964-03-24 Table vii
NL44885C (de) * 1935-11-09
US2805977A (en) * 1955-01-04 1957-09-10 Smith Kline French Lab Sustained release pharmaceutical preparation
US2875130A (en) * 1956-11-20 1959-02-24 Smith Kline French Lab Method of preparing sustained release particles and the product of the method
US3108046A (en) * 1960-11-25 1963-10-22 Smith Kline French Lab Method of preparing high dosage sustained release tablet and product of this method
US3147187A (en) * 1962-09-10 1964-09-01 Don Hall Lab Sustained release pharmaceutical
US3374146A (en) * 1966-04-18 1968-03-19 American Cyanamid Co Sustained release encapsulation
US3539465A (en) * 1968-10-08 1970-11-10 Ncr Co Encapsulation of hydrophilic liquid-in-oil emulsions
US3549555A (en) * 1968-10-08 1970-12-22 Ncr Co Encapsulation of lipophilic liquid-in-hydrophilic liquid emulsions
US3857933A (en) * 1969-10-17 1974-12-31 Hoechst Ag Process for the manufacture of a drug dosage form permitting controlled release of active ingredient
US3851051A (en) * 1970-07-17 1974-11-26 Scherer R Corp Soft gelatin capsule containing high water content fill
GB1405088A (en) * 1971-06-03 1975-09-03 Mundipharma Ag Slow release formulation
DE2363853A1 (de) * 1973-12-21 1975-07-03 Hoechst Ag Selbsttragende packungen oder kapseln zum umhuellen von medikamenten
DE2553026A1 (de) * 1974-12-04 1976-06-10 Schlueter Edelfett Neue formulierungen
US4126672A (en) * 1976-02-04 1978-11-21 Hoffmann-La Roche Inc. Sustained release pharmaceutical capsules
US4167558A (en) * 1976-02-13 1979-09-11 Hoffmann-La Roche Inc. Novel sustained release tablet formulations
US4137300A (en) * 1976-08-20 1979-01-30 Ciba-Geigy Corporation Sustained action dosage forms
US4215117A (en) * 1978-05-26 1980-07-29 The Upjohn Company Stable pharmaceutical formulations
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material
JPS6024767B2 (ja) * 1979-08-24 1985-06-14 塩野義製薬株式会社 腸溶性硬カプセル剤
CH652025A5 (de) * 1981-09-14 1985-10-31 Hoffmann La Roche Pharmazeutisches praeparat.
ATE43205T1 (de) * 1982-03-02 1989-06-15 Siemens Ag Filmtraeger fuer ein elektrisches leiterbild.
US4421736A (en) * 1982-05-20 1983-12-20 Merrel Dow Pharmaceuticals Inc. Sustained release diethylpropion compositions
DK152744C (da) * 1982-08-13 1988-10-31 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat
DK164642C (da) * 1984-08-30 1992-12-14 Merrell Dow Pharma Farmaceutisk middel indeholdende terfenadin i form af en varmsmelte paafyldt paa kapsler

Also Published As

Publication number Publication date
AU5478386A (en) 1986-10-02
DK136186A (da) 1986-09-27
CA1275045A (en) 1990-10-09
DE3681755D1 (de) 1991-11-07
EP0200902B1 (de) 1991-10-02
JPH0772143B2 (ja) 1995-08-02
DK136186D0 (da) 1986-03-24
AU590255B2 (en) 1989-11-02
GB8507779D0 (en) 1985-05-01
EP0200902A2 (de) 1986-11-12
US4690822A (en) 1987-09-01
JPS61233632A (ja) 1986-10-17
EP0200902A3 (en) 1987-09-16

Similar Documents

Publication Publication Date Title
ATE67930T1 (de) Wirkstofftraeger und diesen enthaltende arzneimittel.
DE3686483D1 (de) Arzneimittel.
AU649421B2 (en) Isoxazole-4-carboxamides and hydroxyalkylidene-cyanoacetamides, drugs containing these compounds and use of such drugs
EP0230575A3 (de) Arzneimittel mit Antitumorwirkung das Hexadecylphosphocholin enthält
CA2029524A1 (en) Transdermal administration of 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzothiazole
NO20064159L (no) Nye, biologisk aktive polypeptider, deres fremstilling og farmasoytiske preparater inneholdende polypeptidene
NO903542L (no) Frysetoerket blanding og fremgangsmaate for oral administrering av legemidler, naeringsmidler og biologisk aktive materialer.
DE3676248D1 (de) Ubidecarenon enthaltende arzneimittel.
DE3679920D1 (de) Spiro-3-heteroazolidinverbindungen und ihre salze, ihre herstellung und diese enthaltende pharmazeutische mittel.
NL194239B (nl) Dialkoxyfosfinolmethylbenzamideverbindingen en farmaceutische preparaten, die deze bevatten.
NO163816C (no) Analogifremgangsmaate for fremstilling av nye, terapeutiskaktive piperazinderivater.
DE3765243D1 (de) Ibuprofen und codein enthaltende, stabile, feste arzneimittel.
NO862096L (no) Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende vevsplasminogenaktivator.
DE3685604D1 (de) 1,7-naphthyridinderivate und diese enthaltende arzneimittel.
DE68901859D1 (de) 2-benzothiazolamin-derivate enthaltende arzneimittel, verbindungen und ihre herstellung.
DE3679156D1 (de) Teilbare kapsel.
NO884599D0 (no) Nye quinolin-derivater, fremgangsmaater for fremstilling av disse og antibakterielt middel som inneholder disse.
FI843609A7 (fi) Nestemäiset, ionisia aineosia sisältävät farmaseuttiset valmisteet, jotka pidentävät lääkeaineen vapautumista.
AU3019389A (en) 6-oxo-4,5-dihydro-pyridazine derivatives, a process for their preparation and medicaments containing these compounds
NO162468C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 12-amino-pyridazino (4[,5[;3,4)-pyrrolo-( 2,1-a)-isokinolinderivater.
IT8224871A0 (it) Sistema per la somministrazione di medicamenti, programmabile e trapiantabile.
ATE44143T1 (de) 3-aminopropoxyphenyl-derivate, ihre herstellung und diese enthaltende pharmazeutische mittel.
NO873540D0 (no) Nye analoger av calcemiasenkende polypeptidforbindelser som sparer organismens kalsium, deres fremstilling, deres anvendelse som legemidler og preparater inneholdende dem.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee