ATE80043T1 - Lokal anzuwendende arzneizubereitung zur behandlung von entzuendungserkrankungen. - Google Patents

Lokal anzuwendende arzneizubereitung zur behandlung von entzuendungserkrankungen.

Info

Publication number: ATE80043T1
Authority: AT; Austria
Prior art keywords: inflammatory; treatment; disease; salt; acid
Prior art date: 1988-01-27

Application number

AT89101237T

Other languages

English (en)

Inventor

Takahiro Ogawa

Yoshikazu Kuribayashi

Kazumichi Ushio

Akira Ohtori

Original Assignee

Senju Pharma Co

Robins Co Inc A H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-01-27

Filing date

1989-01-25

Publication date

1992-09-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11923115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE80043(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1989-01-25 Application filed by Senju Pharma Co, Robins Co Inc A H filed Critical Senju Pharma Co

1992-09-15 Application granted granted Critical

1992-09-15 Publication of ATE80043T1 publication Critical patent/ATE80043T1/de

Links

229940079593 drug Drugs 0.000 title abstract 2
239000003814 drug Substances 0.000 title abstract 2
208000027866 inflammatory disease Diseases 0.000 title abstract 2
230000002757 inflammatory effect Effects 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
IVDWXSTVNDRJDG-UHFFFAOYSA-N 2-(4-ethoxyphenyl)-3-oxo-3-phenylpropanoic acid Chemical compound C1=CC(OCC)=CC=C1C(C(O)=O)C(=O)C1=CC=CC=C1 IVDWXSTVNDRJDG-UHFFFAOYSA-N 0.000 abstract 1
208000026344 Nasal disease Diseases 0.000 abstract 1
208000030880 Nose disease Diseases 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
208000030533 eye disease Diseases 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
239000002085 irritant Substances 0.000 abstract 1
231100000021 irritant Toxicity 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Ophthalmology & Optometry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT89101237T 1988-01-27 1989-01-25 Lokal anzuwendende arzneizubereitung zur behandlung von entzuendungserkrankungen. ATE80043T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP1668388		1988-01-27
EP89101237A EP0326915B1 (de)	1988-01-27	1989-01-25	Lokal anzuwendende Arzneizubereitung zur Behandlung von Entzündungserkrankungen

Publications (1)

Publication Number	Publication Date
ATE80043T1 true ATE80043T1 (de)	1992-09-15

Family

ID=11923115

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89101237T ATE80043T1 (de)	1988-01-27	1989-01-25	Lokal anzuwendende arzneizubereitung zur behandlung von entzuendungserkrankungen.

Country Status (12)

Country	Link
US (1)	US4910225A (de)
EP (1)	EP0326915B1 (de)
JP (1)	JP2683676B2 (de)
KR (1)	KR960005707B1 (de)
AT (1)	ATE80043T1 (de)
AU (1)	AU609932B2 (de)
CA (1)	CA1325382C (de)
DE (1)	DE68902649T2 (de)
ES (1)	ES2052784T3 (de)
GR (1)	GR3005586T3 (de)
HK (1)	HK162895A (de)
PH (1)	PH26827A (de)

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US5895645A (en) *	1995-01-31	1999-04-20	Bausch & Lomb Incorporated	Opthalmic solution for artificial tears
RU2116070C1 (ru) *	1996-07-08	1998-07-27	Севиньдж Исмаил кызы Акберова	Фармацевтическая композиция
AR020661A1 (es) *	1998-09-30	2002-05-22	Alcon Lab Inc	Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
DE19961307A1 (de) *	1999-12-18	2001-07-12	Krewel Meuselbach Gmbh	Medizinprodukt zur Befeuchtung und Reinigung der Nasenschleimhaut
AR030346A1 (es)	2000-08-14	2003-08-20	Alcon Inc	Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico
AR030345A1 (es) *	2000-08-14	2003-08-20	Alcon Inc	Metodo de tratamiento de desordenes relacionados con angiogenesis
AU2002247284A1 (en)	2001-04-02	2002-10-15	Alcon, Inc.	Method of treating ocular inflammatory and angiogenesis-related disorders using an amide derivative of flubiprofen or ketorolac
US7030149B2 (en)	2002-04-19	2006-04-18	Allergan, Inc.	Combination of brimonidine timolol for topical ophthalmic use
US20030207941A1 (en) *	2002-05-03	2003-11-06	Bingaman David P.	Method of treating vascular endothelial growth factor mediated vascular disorders
EP1586316B1 (de) *	2003-01-21	2008-04-30	Senju Pharmaceutical Co., Ltd.	Wässrige flüssige zubereitung mit 2-amino-3-(4-bromobenzoyl)phenylessigsäure
US20030187072A1 (en) *	2003-02-14	2003-10-02	Kapin Michael A.	Method of treating angiogenesis-related disorders
CA2527121A1 (en) *	2003-06-13	2004-12-29	Alcon, Inc.	Formulations of non-steroidal anti-inflammatory agents to treat pathologic ocular angiogenesis
ATE552838T1 (de) *	2003-11-14	2012-04-15	Senju Pharma Co	Wässrige lösung mit aminoglykosid-antibiotikum und bromfenac
FR2876581B1 (fr) *	2004-10-20	2007-05-18	Interpharm Dev	Composition bioadhesive a liberation programmee
CN1993118B (zh)	2004-11-05	2010-06-16	千寿制药株式会社	促进眼内渗透性的水性滴眼剂
TWI358290B (en) *	2004-12-02	2012-02-21	Alcon Inc	Topical nepafenac formulations
PT1906916E (pt) *	2005-05-10	2008-12-10	Alcon Inc	Suspensão oftálmica compreendendo um fármaco oftálmico, uma poloxamina e um agente de ajuste da tonicidade de glicol, utilização da referida composição para a produção de um medicamento para o tratamento de distúrbios oftálmicos
DK1885336T3 (da) *	2005-05-10	2009-05-25	Alcon Inc	Suspensionsformuleringer, der omfatter et aktivt princip, et overfladeaktivt poloxamer- eller meroxapolmiddel og en glycol, samt deres anvendelse til fremstilling af et medikament til behandling af öjenlidelser
US20070254841A1 (en) *	2006-01-25	2007-11-01	Ophthalmic Research Associates, Inc.	Formulations and methods for treating dry eye
US20100130580A1 (en) *	2006-01-25	2010-05-27	Aciex Therapeutics, Inc.	Formulations and Methods for Treating Dry Eye
TW200812575A (en) *	2006-04-28	2008-03-16	Alcon Inc	Formulations containing amide derivatives of carboxylic acid NSAIDs for topical administration to the eye
US20090105245A1 (en) *	2006-12-21	2009-04-23	Bingaman David P	Methods for treating macular edema and ocular angiogenesis using an anti-inflammatory agent and a receptor tyrosine kinase inhibitor
US20080153818A1 (en) *	2006-12-21	2008-06-26	Bingaman David P	Methods for preventing inflammation during surgery
US20080153819A1 (en) *	2006-12-21	2008-06-26	Bingaman David P	Methods for treating macular edema and pathologic ocular angiogenesis using a neuroprotective agent and a receptor tyrosine kinase inhibitor
UY31058A1 (es) *	2007-05-01	2008-10-31	Alcon Res Ltd	Formulaciones de aminoacido n-halogenado con compuestos antiinflamatorios
MX2009012645A (es) *	2007-05-24	2010-03-08	Aciex Therapeutics Inc	Formulaciones y metodos para tratar el ojo seco.
BRPI0908502A2 (pt) *	2008-02-21	2017-05-23	Ista Pharmaceuticals	aines oftálmicos como adjuvantes
US8778999B2 (en) *	2009-03-05	2014-07-15	Insite Vision Incorporated	Non-steroidal anti-inflammatory ophthalmic compositions
US8299295B2 (en)	2009-10-15	2012-10-30	Johnson Matthey Public Limited Company	Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
GB0919757D0 (en)	2009-11-12	2009-12-30	Johnson Matthey Plc	Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
US9522153B2 (en)	2009-12-22	2016-12-20	Allergan, Inc.	Compositions and methods for lowering intraocular pressure
WO2012099142A1 (ja)	2011-01-18	2012-07-26	千寿製薬株式会社	保存効力を有するブロムフェナク水性液剤組成物
US9827191B2 (en)	2012-05-03	2017-11-28	The Johns Hopkins University	Compositions and methods for ophthalmic and/or other applications
KR102140989B1 (ko)	2012-05-03	2020-08-04	칼라 파마슈티컬스, 인크.	개선된 점막 수송을 나타내는 제약 나노입자
ES3055223T3 (en)	2012-05-03	2026-02-10	Alcon Inc	Pharmaceutical nanoparticles showing improved mucosal transport
US11596599B2 (en)	2012-05-03	2023-03-07	The Johns Hopkins University	Compositions and methods for ophthalmic and/or other applications
JP6128572B2 (ja)	2012-11-19	2017-05-17	ボシュ・アンド・ロム・インコーポレイテッドＢａｕｓｃｈ＆ＬｏｍｂＩｎｃｏｒｐｏｒａｔｅｄ	２−アミノ−３−（４−ブロモベンゾイル）フェニル酢酸を含有する水性液体組成物
HK1217092A1 (zh)	2013-02-15	2016-12-23	Kala Pharmaceuticals, Inc.	治疗性化合物及其用途
BR112015020139A2 (pt)	2013-02-20	2017-07-18	Kala Pharmaceuticals Inc	compostos terapêuticos e usos dos mesmos
US9688688B2 (en)	2013-02-20	2017-06-27	Kala Pharmaceuticals, Inc.	Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof
US20160143869A1 (en)	2013-06-19	2016-05-26	Sentiss Research Center	Stable bromfenac solution
KR20160099084A (ko)	2013-11-01	2016-08-19	칼라 파마슈티컬스, 인크.	치료 화합물의 결정질 형태 및 그의 용도
US9890173B2 (en)	2013-11-01	2018-02-13	Kala Pharmaceuticals, Inc.	Crystalline forms of therapeutic compounds and uses thereof
WO2015087267A2 (en)	2013-12-12	2015-06-18	Sentiss Pharma Private Limited	Stable bromfenac ophthalmic solution
CN106404952B (zh) *	2016-08-31	2019-06-11	辰欣佛都药业（汶上）有限公司	一种溴芬酸钠滴眼液有关物质的测定方法
EP3509423A4 (de)	2016-09-08	2020-05-13	Kala Pharmaceuticals, Inc.	Kristalline formen von therapeutischen verbindungen und verwendungen davon
CA3036336A1 (en)	2016-09-08	2018-03-15	Kala Pharmaceuticals, Inc.	Crystalline forms of therapeutic compounds and uses thereof
CA3036065A1 (en)	2016-09-08	2018-03-15	Kala Pharmaceuticals, Inc.	Crystalline forms of therapeutic compounds and uses thereof
JPWO2019117252A1 (ja) *	2017-12-14	2020-12-17	参天製薬株式会社	２−アミノ−３−（４−ブロモベンゾイル）フェニル酢酸またはその塩を含有する点眼剤
WO2022092868A1 (ko)	2020-10-29	2022-05-05	주식회사태준제약	안과용 조성물
KR102489633B1 (ko)	2021-01-21	2023-01-17	주식회사태준제약	점안 조성물

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AU512570B2 (en) *	1975-08-13	1980-10-16	A.H. Robins Company, Incorporated	Amino benzophenones
CH577461A5 (de) *	1975-08-13	1976-07-15	Robins Co Inc A H
JPS58201710A (ja) *	1982-05-18	1983-11-24	Meiji Seika Kaisha Ltd	口腔内用抗炎症ペ−スト剤
US4568695A (en) *	1983-12-07	1986-02-04	A. H. Robins Company, Incorporated	2-Amino-3-benzoyl-phenethylalcohols and intermediates therefor
US4683242A (en) *	1985-10-28	1987-07-28	A. H. Robins Company, Incorporated	Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters

1989
- 1989-01-24 CA CA000589025A patent/CA1325382C/en not_active Expired - Lifetime
- 1989-01-24 US US07/301,033 patent/US4910225A/en not_active Expired - Lifetime
- 1989-01-25 DE DE8989101237T patent/DE68902649T2/de not_active Expired - Lifetime
- 1989-01-25 ES ES89101237T patent/ES2052784T3/es not_active Expired - Lifetime
- 1989-01-25 AT AT89101237T patent/ATE80043T1/de not_active IP Right Cessation
- 1989-01-25 AU AU28786/89A patent/AU609932B2/en not_active Expired
- 1989-01-25 EP EP89101237A patent/EP0326915B1/de not_active Expired - Lifetime
- 1989-01-26 PH PH38108A patent/PH26827A/en unknown
- 1989-01-27 KR KR1019890000892A patent/KR960005707B1/ko not_active Expired - Lifetime
- 1989-01-27 JP JP1018549A patent/JP2683676B2/ja not_active Expired - Lifetime
1992
- 1992-09-03 GR GR920401848T patent/GR3005586T3/el unknown
1995
- 1995-10-19 HK HK162895A patent/HK162895A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE68902649T2 (de)	1993-02-11
US4910225A (en)	1990-03-20
AU609932B2 (en)	1991-05-09
CA1325382C (en)	1993-12-21
DE68902649D1 (de)	1992-10-08
HK162895A (en)	1995-10-27
JP2683676B2 (ja)	1997-12-03
KR960005707B1 (ko)	1996-05-01
JPH02124817A (ja)	1990-05-14
EP0326915A1 (de)	1989-08-09
KR890011823A (ko)	1989-08-22
AU2878689A (en)	1989-07-27
ES2052784T3 (es)	1994-07-16
GR3005586T3 (de)	1993-06-07
EP0326915B1 (de)	1992-09-02
PH26827A (en)	1992-11-05

Legal Events

Date	Code	Title
1993-02-15	UEP	Publication of translation of european patent specification
1999-11-15	EEIH	Change in the person of patent owner
2009-04-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
ATE80043T1 (de)	1992-09-15	Lokal anzuwendende arzneizubereitung zur behandlung von entzuendungserkrankungen.
NO912410D0 (no)	1991-06-20	Fremgangsmaate for fremstilling av terapeutisk aktive heterocyklen-derivater.
KR900015722A (ko)	1990-11-10	N-(3,4-디메톡시신나모일) 안트라닐산을 함유하는 약제 조성물
ATE388700T1 (de)	2008-03-15	Therapeutische zusammensetzungen von venösdilatoren und arterielldilatoren
ATE73331T1 (de)	1992-03-15	Verwendung von tetrahydrobiopterinen zur herstellung eines medikaments zur behandlung von kinderautismus.
BR0014179A (pt)	2002-05-21	Modernos derivados de ácido aminodicarboxìlico com propriedades farmacêuticas
KR880000091A (ko)	1988-03-23	국소용 약제학적 조성물 이의 제조방법 및 이의 용도
BRPI0210707B8 (pt)	2021-05-25	composição de solução para administração tópica no tratamento de distúrbios alérgicos ou inflamatórios do olho e do nariz e seu método de preparação
DE4394931T1 (de)	1995-07-20	Verwendung von Norastemizol zur Behandlung von allergischen Erkrankungen
NO166939C (no)	1991-09-18	Analogifremgangsmaate for fremstilling av terapeutisk aktive carboxylsyrederivater.
RU99121654A (ru)	2001-08-20	Средства для предотвращения или лечения болезней, связанных с чрезмерной пролиферацией эпителиальных пигментных клеток сетчатки
US4197301A (en)	1980-04-08	Topical ophthalmic use of Prazosin
JPS6410500B2 (de)	1989-02-22
ATE161725T1 (de)	1998-01-15	Verwendung von phosphatdiestern zur behandlung von erkrankungen der retina
DE69524780D1 (de)	2002-01-31	Verwendung von indolderivaten zur behandlung von dermatologischen krankheiten, peridhren neuropathien, arthritis, allergischen oder chronisch-obstruktiven atemwegserkrankungen, glaukom und augenentzündungen
KR930019224A (ko)	1993-10-18	유산 위험 치료제
ATE110568T1 (de)	1994-09-15	Pharmazeutisches präparat zur behandlung des katarakts.
DK1174131T3 (da)	2007-02-05	Anvendelse af et middel til forbedring af astrocytfunktion til behandling af Parkinsons sygdom
ATE38982T1 (de)	1988-12-15	Guanidinmethylcyclohexancarbonsaeure-derivate, verfahren zur herstellung und pharmazeutische mittel.
KR870006035A (ko)	1987-07-08	신규 항균제 1-티에닐-4-옥소퀴놀린-3-카복실산 화합물의 제법
DE60327179D1 (de)	2009-05-28	Behandlung von augenkrankheiten mit harnstoff und harnstoffderivaten
EP1325918A4 (de)	2004-03-10	Herzmuskelzellen-apoptose hemmstoffe und behandlung/vorbeugung von herzkrankheiten
RU2073523C1 (ru)	1997-02-20	Препарат для лечения ожоговой болезни глаз i-iy степеней
DE69910706D1 (de)	2003-10-02	Medikament zur Behandlung von Glaukoma und ischämischer Retinopathie
ATE212842T1 (de)	2002-02-15	Quinoxalin-derivate zur behandlung von tinnitus