PH26827A - A locally administrable therapeutic composition for inflammatory disease - Google Patents

A locally administrable therapeutic composition for inflammatory disease Download PDF

Info

Publication number
PH26827A
PH26827A PH38108A PH38108A PH26827A PH 26827 A PH26827 A PH 26827A PH 38108 A PH38108 A PH 38108A PH 38108 A PH38108 A PH 38108A PH 26827 A PH26827 A PH 26827A
Authority
PH
Philippines
Prior art keywords
eye
inflammatory
acid
sodium
salt
Prior art date
Application number
PH38108A
Other languages
English (en)
Inventor
Takahiro Ogawa
Yoshikazu Kuribayashi
Original Assignee
Senju Pharma Co
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11923115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH26827(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Senju Pharma Co, Robins Co Inc A H filed Critical Senju Pharma Co
Priority to PH42478A priority Critical patent/PH30230A/en
Publication of PH26827A publication Critical patent/PH26827A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PH38108A 1988-01-27 1989-01-26 A locally administrable therapeutic composition for inflammatory disease PH26827A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PH42478A PH30230A (en) 1988-01-27 1991-05-20 A locally administrable therapeutic composition for inflammatory disease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1668388 1988-01-27

Publications (1)

Publication Number Publication Date
PH26827A true PH26827A (en) 1992-11-05

Family

ID=11923115

Family Applications (1)

Application Number Title Priority Date Filing Date
PH38108A PH26827A (en) 1988-01-27 1989-01-26 A locally administrable therapeutic composition for inflammatory disease

Country Status (12)

Country Link
US (1) US4910225A (de)
EP (1) EP0326915B1 (de)
JP (1) JP2683676B2 (de)
KR (1) KR960005707B1 (de)
AT (1) ATE80043T1 (de)
AU (1) AU609932B2 (de)
CA (1) CA1325382C (de)
DE (1) DE68902649T2 (de)
ES (1) ES2052784T3 (de)
GR (1) GR3005586T3 (de)
HK (1) HK162895A (de)
PH (1) PH26827A (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5897858A (en) 1994-02-03 1999-04-27 Schering-Plough Healthcare Products, Inc. Nasal spray compositions exhibiting increased retention in the nasal cavity
US5475034A (en) * 1994-06-06 1995-12-12 Alcon Laboratories, Inc. Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
US5895645A (en) * 1995-01-31 1999-04-20 Bausch & Lomb Incorporated Opthalmic solution for artificial tears
RU2116070C1 (ru) * 1996-07-08 1998-07-27 Севиньдж Исмаил кызы Акберова Фармацевтическая композиция
AR020661A1 (es) * 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
DE19961307A1 (de) * 1999-12-18 2001-07-12 Krewel Meuselbach Gmbh Medizinprodukt zur Befeuchtung und Reinigung der Nasenschleimhaut
AR030346A1 (es) 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
AU2002247284A1 (en) 2001-04-02 2002-10-15 Alcon, Inc. Method of treating ocular inflammatory and angiogenesis-related disorders using an amide derivative of flubiprofen or ketorolac
US7030149B2 (en) 2002-04-19 2006-04-18 Allergan, Inc. Combination of brimonidine timolol for topical ophthalmic use
US20030207941A1 (en) * 2002-05-03 2003-11-06 Bingaman David P. Method of treating vascular endothelial growth factor mediated vascular disorders
EP1586316B1 (de) * 2003-01-21 2008-04-30 Senju Pharmaceutical Co., Ltd. Wässrige flüssige zubereitung mit 2-amino-3-(4-bromobenzoyl)phenylessigsäure
US20030187072A1 (en) * 2003-02-14 2003-10-02 Kapin Michael A. Method of treating angiogenesis-related disorders
CA2527121A1 (en) * 2003-06-13 2004-12-29 Alcon, Inc. Formulations of non-steroidal anti-inflammatory agents to treat pathologic ocular angiogenesis
ATE552838T1 (de) * 2003-11-14 2012-04-15 Senju Pharma Co Wässrige lösung mit aminoglykosid-antibiotikum und bromfenac
FR2876581B1 (fr) * 2004-10-20 2007-05-18 Interpharm Dev Composition bioadhesive a liberation programmee
CN1993118B (zh) 2004-11-05 2010-06-16 千寿制药株式会社 促进眼内渗透性的水性滴眼剂
TWI358290B (en) * 2004-12-02 2012-02-21 Alcon Inc Topical nepafenac formulations
PT1906916E (pt) * 2005-05-10 2008-12-10 Alcon Inc Suspensão oftálmica compreendendo um fármaco oftálmico, uma poloxamina e um agente de ajuste da tonicidade de glicol, utilização da referida composição para a produção de um medicamento para o tratamento de distúrbios oftálmicos
DK1885336T3 (da) * 2005-05-10 2009-05-25 Alcon Inc Suspensionsformuleringer, der omfatter et aktivt princip, et overfladeaktivt poloxamer- eller meroxapolmiddel og en glycol, samt deres anvendelse til fremstilling af et medikament til behandling af öjenlidelser
US20070254841A1 (en) * 2006-01-25 2007-11-01 Ophthalmic Research Associates, Inc. Formulations and methods for treating dry eye
US20100130580A1 (en) * 2006-01-25 2010-05-27 Aciex Therapeutics, Inc. Formulations and Methods for Treating Dry Eye
TW200812575A (en) * 2006-04-28 2008-03-16 Alcon Inc Formulations containing amide derivatives of carboxylic acid NSAIDs for topical administration to the eye
US20090105245A1 (en) * 2006-12-21 2009-04-23 Bingaman David P Methods for treating macular edema and ocular angiogenesis using an anti-inflammatory agent and a receptor tyrosine kinase inhibitor
US20080153818A1 (en) * 2006-12-21 2008-06-26 Bingaman David P Methods for preventing inflammation during surgery
US20080153819A1 (en) * 2006-12-21 2008-06-26 Bingaman David P Methods for treating macular edema and pathologic ocular angiogenesis using a neuroprotective agent and a receptor tyrosine kinase inhibitor
UY31058A1 (es) * 2007-05-01 2008-10-31 Alcon Res Ltd Formulaciones de aminoacido n-halogenado con compuestos antiinflamatorios
MX2009012645A (es) * 2007-05-24 2010-03-08 Aciex Therapeutics Inc Formulaciones y metodos para tratar el ojo seco.
BRPI0908502A2 (pt) * 2008-02-21 2017-05-23 Ista Pharmaceuticals aines oftálmicos como adjuvantes
US8778999B2 (en) * 2009-03-05 2014-07-15 Insite Vision Incorporated Non-steroidal anti-inflammatory ophthalmic compositions
US8299295B2 (en) 2009-10-15 2012-10-30 Johnson Matthey Public Limited Company Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
GB0919757D0 (en) 2009-11-12 2009-12-30 Johnson Matthey Plc Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
WO2012099142A1 (ja) 2011-01-18 2012-07-26 千寿製薬株式会社 保存効力を有するブロムフェナク水性液剤組成物
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
KR102140989B1 (ko) 2012-05-03 2020-08-04 칼라 파마슈티컬스, 인크. 개선된 점막 수송을 나타내는 제약 나노입자
ES3055223T3 (en) 2012-05-03 2026-02-10 Alcon Inc Pharmaceutical nanoparticles showing improved mucosal transport
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
JP6128572B2 (ja) 2012-11-19 2017-05-17 ボシュ・アンド・ロム・インコーポレイテッドBausch & Lomb Incorporated 2−アミノ−3−(4−ブロモベンゾイル)フェニル酢酸を含有する水性液体組成物
HK1217092A1 (zh) 2013-02-15 2016-12-23 Kala Pharmaceuticals, Inc. 治疗性化合物及其用途
BR112015020139A2 (pt) 2013-02-20 2017-07-18 Kala Pharmaceuticals Inc compostos terapêuticos e usos dos mesmos
US9688688B2 (en) 2013-02-20 2017-06-27 Kala Pharmaceuticals, Inc. Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof
US20160143869A1 (en) 2013-06-19 2016-05-26 Sentiss Research Center Stable bromfenac solution
KR20160099084A (ko) 2013-11-01 2016-08-19 칼라 파마슈티컬스, 인크. 치료 화합물의 결정질 형태 및 그의 용도
US9890173B2 (en) 2013-11-01 2018-02-13 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
WO2015087267A2 (en) 2013-12-12 2015-06-18 Sentiss Pharma Private Limited Stable bromfenac ophthalmic solution
CN106404952B (zh) * 2016-08-31 2019-06-11 辰欣佛都药业(汶上)有限公司 一种溴芬酸钠滴眼液有关物质的测定方法
EP3509423A4 (de) 2016-09-08 2020-05-13 Kala Pharmaceuticals, Inc. Kristalline formen von therapeutischen verbindungen und verwendungen davon
CA3036336A1 (en) 2016-09-08 2018-03-15 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
CA3036065A1 (en) 2016-09-08 2018-03-15 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
JPWO2019117252A1 (ja) * 2017-12-14 2020-12-17 参天製薬株式会社 2−アミノ−3−(4−ブロモベンゾイル)フェニル酢酸またはその塩を含有する点眼剤
WO2022092868A1 (ko) 2020-10-29 2022-05-05 주식회사태준제약 안과용 조성물
KR102489633B1 (ko) 2021-01-21 2023-01-17 주식회사태준제약 점안 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU512570B2 (en) * 1975-08-13 1980-10-16 A.H. Robins Company, Incorporated Amino benzophenones
CH577461A5 (de) * 1975-08-13 1976-07-15 Robins Co Inc A H
JPS58201710A (ja) * 1982-05-18 1983-11-24 Meiji Seika Kaisha Ltd 口腔内用抗炎症ペ−スト剤
US4568695A (en) * 1983-12-07 1986-02-04 A. H. Robins Company, Incorporated 2-Amino-3-benzoyl-phenethylalcohols and intermediates therefor
US4683242A (en) * 1985-10-28 1987-07-28 A. H. Robins Company, Incorporated Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters

Also Published As

Publication number Publication date
DE68902649T2 (de) 1993-02-11
US4910225A (en) 1990-03-20
AU609932B2 (en) 1991-05-09
CA1325382C (en) 1993-12-21
DE68902649D1 (de) 1992-10-08
HK162895A (en) 1995-10-27
JP2683676B2 (ja) 1997-12-03
ATE80043T1 (de) 1992-09-15
KR960005707B1 (ko) 1996-05-01
JPH02124817A (ja) 1990-05-14
EP0326915A1 (de) 1989-08-09
KR890011823A (ko) 1989-08-22
AU2878689A (en) 1989-07-27
ES2052784T3 (es) 1994-07-16
GR3005586T3 (de) 1993-06-07
EP0326915B1 (de) 1992-09-02

Similar Documents

Publication Publication Date Title
PH26827A (en) A locally administrable therapeutic composition for inflammatory disease
US5110493A (en) Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant
NL192821C (nl) Oftalmische oplossing.
HU211972A9 (en) Antiallergic composition for ophthalmic or nasal use
HK27894A (en) Preservative system for ophtalmic formulations
CN107405360B (zh) 新颖碘伏组合物及其使用方法
JPS6038323A (ja) 眼科用消炎剤
JPH0696521B2 (ja) 眼局所投与用眼圧降下剤
CN101175487B (zh) 依布硒啉的制药用途
US10973758B2 (en) Methods of eye treatment using therapeutic compositions containing dipyridamole
JP6320616B1 (ja) 新規眼科用組成物および使用方法
WO2019135779A1 (en) Novel ophthalmic composition and methods of use
JPS5929616A (ja) 抗炎症眼科用液剤およびその製法
EP0728480A1 (de) Verwendung von Ifenprodil zur Behandlung von erhöhtem Augeninnendruck
US5428030A (en) Method of reducing elevated intraocular pressure
RU2657419C1 (ru) Фармацевтическая композиция для назального применения
KR950013745B1 (ko) 안과 제제용 방부 시스템
JPH10203979A (ja) チアプロフェン酸を含有する抗眼炎症剤
JPH0778022B2 (ja) 緑内障治療剤
JPS63201122A (ja) トリフルオロメタンスルホンアミドを含有する緑内障治療配合物
US20180200289A1 (en) Novel ophthalmic composition and methods of use
JP2002322060A (ja) 粘膜適用組成物
JPS63179825A (ja) 局所抗炎症剤
JPH0797318A (ja) オキシフェドリンを必須成分とする眼圧降下剤
JPH09295935A (ja) 抗眼炎症剤