ATE83773T1 - 3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a. - Google Patents

3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a.

Info

Publication number: ATE83773T1
Authority: AT; Austria
Prior art keywords: hydrogen; alkyl; branched; straight chained; pyridazinone
Prior art date: 1987-01-20

Application number

AT88100798T

Other languages

English (en)

Inventor

Keizo Tanikawa

Ryozo Sakoda

Ken-Ichi Shikada

Original Assignee

Nissan Chemical Ind Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-01-20

Filing date

1988-01-20

Publication date

1993-01-15

1988-01-20 Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd

1993-01-15 Application granted granted Critical

1993-01-15 Publication of ATE83773T1 publication Critical patent/ATE83773T1/de

Links

AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical compound OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 title abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 11
239000001257 hydrogen Substances 0.000 abstract 11
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 10
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 6
229910052736 halogen Chemical group 0.000 abstract 3
150000002367 halogens Chemical group 0.000 abstract 3
125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 2
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
229910052794 bromium Chemical group 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
125000001309 chloro group Chemical group Cl* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
239000011593 sulfur Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pulmonology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT88100798T 1987-01-20 1988-01-20 3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a. ATE83773T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP1023187		1987-01-20
EP88100798A EP0275997B1 (de)	1987-01-20	1988-01-20	3(2H)Pyridazinon, Verfahren zu dessen Herstellung und dieses enthaltendes Mittel gegen SRS-A

Publications (1)

Publication Number	Publication Date
ATE83773T1 true ATE83773T1 (de)	1993-01-15

Family

ID=11744513

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88100798T ATE83773T1 (de)	1987-01-20	1988-01-20	3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a.

Country Status (10)

Country	Link
US (1)	US4978665A (de)
EP (1)	EP0275997B1 (de)
AT (1)	ATE83773T1 (de)
AU (1)	AU597141B2 (de)
CA (1)	CA1324792C (de)
DD (1)	DD287497A5 (de)
DE (2)	DE3876813D1 (de)
HU (1)	HU198696B (de)
SU (1)	SU1584750A3 (de)
ZA (1)	ZA88309B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0641455B2 (ja) *	1984-12-10	1994-06-01	日産化学工業株式会社	ピリダジノン誘導体
IE62890B1 (en) *	1988-12-06	1995-03-08	Hafslund Nycomed Pharma	New piperazinylalkyl-3(2h)-pyridazinones process for the preparation thereof and the use thereof as agents lowering blood pressure
JPH02256668A (ja) *	1988-12-20	1990-10-17	Nissan Chem Ind Ltd	ピリダジノン誘導体
DE4009761A1 (de) *	1989-07-28	1991-01-31	Bayer Ag	2h-pyridazinon-derivate
HU208124B (en) *	1990-04-25	1993-08-30	Nissan Chemical Ind Ltd	Process for producing pyridazinone derivatives and pharmaceutical compositions comprising such derivatives as active ingredient
JPH0517357A (ja) *	1991-07-05	1993-01-26	Nissan Chem Ind Ltd	血小板減少療法剤
IL110040A (en) *	1993-06-29	2000-07-16	Nissan Chemical Ind Ltd	Pyridazinone derivatives their preparation and pharmaceutical compositions comprising them
US5763439A (en) *	1993-09-06	1998-06-09	Ishihara Sangyo Kaisha Ltd.	Pyridazinone derivatives or their salts, processes for their production, and anti-shock agents containing them
NZ270130A (en) *	1993-12-16	1995-12-21	Nihon Nohyaku Co Ltd	Pyridazinone derivatives, preparation and pharmaceutical compositions thereof
ES2147841T3 (es) *	1994-01-25	2000-10-01	Nissan Chemical Ind Ltd	Derivados de piridazinona.
IL112695A (en) *	1994-02-22	1999-04-11	Green Cross Corp	Pharmaceutical compositions containing pyridazinone derivatives
DE19516350A1 (de) *	1995-05-04	1996-11-07	Du Pont Deutschland	Photothermographisches lichtempfindliches Aufzeichnungsmaterial mit vermindertem Schleier
CN1163230C (zh) *	1998-12-07	2004-08-25	日产化学工业株式会社	勃起功能障碍治疗剂
US7132445B2 (en)	2001-04-16	2006-11-07	Schering Corporation	3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
US20040106794A1 (en)	2001-04-16	2004-06-03	Schering Corporation	3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
MXPA04003439A (es)	2001-10-12	2004-07-08	Schering Corp	Compuestos de maleimida 3,4 disustituidos como antagonistas de receptor de quimiocina cxc.
US6878709B2 (en)	2002-01-04	2005-04-12	Schering Corporation	3,4-di-substituted pyridazinediones as CXC chemokine receptor antagonists
US20040053953A1 (en)	2002-03-18	2004-03-18	Schering Corporation	Treatment of chemokine mediated diseases
CN1720240B (zh)	2002-10-09	2010-10-27	先灵公司	作为cxc-和cc-趋化因子受体配体的噻二唑二氧化物和噻二唑氧化物
JP4939229B2 (ja)	2003-12-19	2012-05-23	シェーリングコーポレイション	Ｃｘｃ−ケモカインレセプターリガンドおよびｃｃ−ケモカインレセプターリガンドとしてのチアジアゾール
WO2005068460A1 (en)	2003-12-22	2005-07-28	Schering Corporation	Isothiazole dioxides as cxc- and cc- chemokine receptor ligands
CA2613428A1 (en)	2005-06-29	2007-01-11	Schering Corporation	5,6-di-substituted oxadiazolopyrazines and thiadiazolopyrazines as cxc-chemokine receptor ligands
CN101253165A (zh)	2005-06-29	2008-08-27	先灵公司	作为cxc－化学活素受体配体的二取代的二唑
SG11202102624SA (en) *	2018-09-27	2021-04-29	Fmc Corp	Intermediates for preparing herbicidal pyridazinones

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA784639A (en) *		1968-05-07	C. Olson Harold	Herbicidal compositions
FR1441438A (fr) *	1963-11-13	1966-06-10	Basf Ag	Procédé pour la préparation de nitro-4 amino-5 pyridazones-6
FR1413955A (fr) *	1964-06-03	1965-10-15	Basf Ag	Procédé pour la préparation d'amino-4 halogéno-5 pyridazones-6
US4296120A (en) *	1980-08-28	1981-10-20	Pfizer Inc.	(Carboxy-oxo-pyrrolidino)phenylalkenamides and esters thereof as SRS-A antagonists
JPH0641455B2 (ja) *	1984-12-10	1994-06-01	日産化学工業株式会社	ピリダジノン誘導体
JPH0641454B2 (ja) *	1985-02-27	1994-06-01	日産化学工業株式会社	ピリダジノン誘導体
EP0201765B1 (de) *	1985-04-27	1991-09-18	Nissan Chemical Industries Ltd.	3(2H) Pyridazinone, Verfahren zu ihrer Herstellung und diese enthaltende anti-allergische Mittel

1988
- 1988-01-15 US US07/144,173 patent/US4978665A/en not_active Expired - Fee Related
- 1988-01-15 HU HU88152A patent/HU198696B/hu not_active IP Right Cessation
- 1988-01-18 ZA ZA880309A patent/ZA88309B/xx unknown
- 1988-01-18 CA CA000556722A patent/CA1324792C/en not_active Expired - Fee Related
- 1988-01-19 DD DD88312298A patent/DD287497A5/de not_active IP Right Cessation
- 1988-01-19 SU SU884355078A patent/SU1584750A3/ru active
- 1988-01-19 AU AU10396/88A patent/AU597141B2/en not_active Ceased
- 1988-01-20 DE DE8888100798A patent/DE3876813D1/de not_active Expired - Fee Related
- 1988-01-20 DE DE3876813T patent/DE3876813T4/de not_active Expired - Lifetime
- 1988-01-20 EP EP88100798A patent/EP0275997B1/de not_active Expired - Lifetime
- 1988-01-20 AT AT88100798T patent/ATE83773T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
DD287497A5 (de)	1991-02-28
EP0275997A1 (de)	1988-07-27
US4978665A (en)	1990-12-18
HU198696B (en)	1989-11-28
DE3876813T2 (de)	1993-04-29
SU1584750A3 (ru)	1990-08-07
AU1039688A (en)	1988-07-21
DE3876813T4 (de)	1995-05-11
EP0275997B1 (de)	1992-12-23
ZA88309B (en)	1988-07-01
HUT46313A (en)	1988-10-28
CA1324792C (en)	1993-11-30
DE3876813D1 (de)	1993-02-04
AU597141B2 (en)	1990-05-24

Legal Events

Date	Code	Title	Description
1993-06-15	UEP	Publication of translation of european patent specification
1997-10-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE83773T1 (de)	1993-01-15	3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a.
JPS568361A (en)	1981-01-28	Pyroglutamic acid derivative and analogue
FI892787A0 (fi)	1989-06-07	Analogiamenetelmä terapeuttisesti käyttökelpoisten 1-indolyylialkyyli-4-(substituoitu pyridinyyli)piperatsiinien valmistamiseksi
MY102866A (en)	1993-03-31	Amide derivatives.
EP0787726A4 (de)	1997-08-06
TW368501B (en)	1999-09-01	7-(2-aminoethyl)-benzothiazolones
GB0018272D0 (en)	2000-09-13	Chemical compounds IV
DE69129175D1 (de)	1998-05-07	1-Methylcarbapenemderivate und Verfahren zu ihrer Herstellung
ATE44748T1 (de)	1989-08-15	4-substituierte 6-alkylidene-androsten-3,17-dion- derivate und verfahren zu ihrer herstellung.
CO4980887A1 (es)	2000-11-27	Nueva 3,4-diariltiazolina-2-uno o 2-tiono derivados, sus metodos de preparacion y su uso terapeutico
ATE53032T1 (de)	1990-06-15	2-thiazolylimidazo(1,2-a)pyrimidine und ihre salze, verfahren zu ihrer herstellung, ihre anwendung als arzneimittel und diese enthaltende zubereitungen.
ES2073258T3 (es)	1995-08-01	Nuevos derivados de la urea, su preparacion y su aplicacion en terapeutica.
NZ221699A (en)	1990-03-27	Pyridazinone derivatives; pharmaceutical compositions and intermediates
GR3030234T3 (en)	1999-08-31	4-Phenylcarbamoyl-3-isoxazolecarboxylic acid derivatives with antiinflammatory activity
ES455741A1 (es)	1978-04-16	Un procedimiento para la preparacion de nuevos derivados de 1,3-bencenodimetanol.
MY109714A (en)	1997-04-30	Process for preparing 8-chloroquinolone derivatives
AP1518A (en)	2005-12-12	Novel octahydro-6, 10-dioxo-6h-pyridazino/1,2-a/ /1,2/diazepin-1-carboxylic acid derivatives, preparation method and use for preparing therapeutically active compounds.
ZA807337B (en)	1982-08-25	2-phenylamino-imidazolines-(2),processes for their preparation,and pharmaceutical compositions thereof
NZ504299A (en)	2001-01-26	1-aza-2-alkyl-6-aryl-cycloalkane compounds, a process for their preparation and pharmaceutical compositions containing them
ES479110A1 (es)	1979-07-01	Procedimiento para preparar derivados de benzamidina.
ATE52509T1 (de)	1990-05-15	Thiazolidinderivate und verfahren zu ihrer herstellung.
DE69303352D1 (de)	1996-08-01	Verfahren zur Herstellung 5-Pyrazolomerkaptan-Derivate und dessen zwischenprodukte
ATE53839T1 (de)	1990-06-15	2,3-dihydro-3-phenyl-benzofuran-2-onacetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
HUP0204144A2 (en)	2003-05-28	N-(1-phenylethyl)-5-phenyl-imidazole-2-amine compounds, their compositions and uses
EP0443474A3 (en)	1992-04-22	1-phenoxycarbonyl-2-pyrrolidinone derivatives and nootropic agents