ATE84714T1 - Transkutane verabreichung von pharmazeutika. - Google Patents

Transkutane verabreichung von pharmazeutika.

Info

Publication number: ATE84714T1
Authority: AT; Austria
Prior art keywords: pharmaceuticals; transcutaneous administration; enantiomers; transcutaneous; administration
Prior art date: 1987-06-12

Application number

AT88107473T

Other languages

English (en)

Inventor

John Michael Pawelchak

James Ronald Lawter

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-06-12

Filing date

1988-05-10

Publication date

1993-02-15

1988-05-10 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1993-02-15 Application granted granted Critical

1993-02-15 Publication of ATE84714T1 publication Critical patent/ATE84714T1/de

Links

239000003814 drug Substances 0.000 title 1
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 2
239000000203 mixture Substances 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 1
230000037317 transdermal delivery Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Dermatology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Oil, Petroleum & Natural Gas (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT88107473T 1987-06-12 1988-05-10 Transkutane verabreichung von pharmazeutika. ATE84714T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US6184287A	1987-06-12	1987-06-12
EP88107473A EP0294601B1 (de)	1987-06-12	1988-05-10	Transkutane Verabreichung von Pharmazeutika

Publications (1)

Publication Number	Publication Date
ATE84714T1 true ATE84714T1 (de)	1993-02-15

Family

ID=22038497

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88107473T ATE84714T1 (de)	1987-06-12	1988-05-10	Transkutane verabreichung von pharmazeutika.

Country Status (16)

Country	Link
EP (1)	EP0294601B1 (de)
JP (1)	JP2654092B2 (de)
KR (1)	KR970000506B1 (de)
AT (1)	ATE84714T1 (de)
AU (1)	AU609142B2 (de)
CA (1)	CA1305418C (de)
DE (1)	DE3877630T2 (de)
DK (1)	DK171746B1 (de)
ES (1)	ES2043719T3 (de)
GR (1)	GR3006938T3 (de)
IE (1)	IE62735B1 (de)
IL (1)	IL86334A (de)
NO (1)	NO178096C (de)
NZ (1)	NZ224891A (de)
PT (1)	PT87704B (de)
ZA (1)	ZA884186B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5045553A (en) *	1987-06-24	1991-09-03	Fujisawa Pharmaceutical Company, Ltd.	Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter
US5476854A (en) *	1991-11-27	1995-12-19	Sepracor Inc.	Methods and compositions for treating bacterial infection using optically pure (R)-lomefloxacin
US6075024A (en)	1991-11-27	2000-06-13	Sepracor Inc.	Methods for treating infection using optically pure (S)-lomefloxacin
US5834496A (en) *	1991-12-02	1998-11-10	Sepracor, Inc.	Methods for treating hypertension using optically pure S(-) felodipine
AU5596394A (en) *	1992-11-09	1994-06-08	Pharmetrix Corporation	Transdermal delivery of ketorolac
TWI277418B (en)	2001-06-18	2007-04-01	Noven Pharma	Enhanced drug delivery in transdermal systems
WO2004110354A2 (en)	2003-05-15	2004-12-23	Roskamp Research, Llc	Method for reducing amyloid deposition, amyloid neurotoxicity and microgliosis
CN101883564B (zh)	2007-10-05	2013-10-16	阿尔茨海默病学会美国公司	使用(-)-尼伐地平对映体减少淀粉状蛋白沉积、淀粉状蛋白神经毒性和小神经胶质增生的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4284634A (en) *	1975-07-02	1981-08-18	Fujisawa Pharmaceutical Co., Ltd.	1,4-Dihydropyridine derivatives, and pharmaceutical method of the same
US4338322A (en) *	1975-07-02	1982-07-06	Fujisawa Pharmaceutical Co., Ltd.	1,4-Dihydropyridine derivatives, pharmaceutical compositions containing same and methods of effecting vasodilation using same
CA1117117A (en) *	1978-10-10	1982-01-26	Fujisawa Pharmaceutical Co., Ltd.	2-methyl-dihydropyridine compound, processes for preparation thereof and pharmaceutical composition comprising the same
JPS6016917A (ja) *	1983-07-08	1985-01-28	Yamanouchi Pharmaceut Co Ltd	塩酸ニカルジピンまたはニフエジピンの軟膏剤
DE3419128A1 (de) *	1984-05-23	1985-11-28	Bayer Ag, 5090 Leverkusen	Dihydropyridinpraeparate und verfahren zu ihrer herstellung

1988
- 1988-05-10 DE DE8888107473T patent/DE3877630T2/de not_active Expired - Lifetime
- 1988-05-10 AT AT88107473T patent/ATE84714T1/de not_active IP Right Cessation
- 1988-05-10 EP EP88107473A patent/EP0294601B1/de not_active Expired - Lifetime
- 1988-05-10 ES ES88107473T patent/ES2043719T3/es not_active Expired - Lifetime
- 1988-05-11 IL IL86334A patent/IL86334A/xx not_active IP Right Cessation
- 1988-06-03 NZ NZ224891A patent/NZ224891A/en unknown
- 1988-06-09 PT PT87704A patent/PT87704B/pt not_active IP Right Cessation
- 1988-06-10 ZA ZA884186A patent/ZA884186B/xx unknown
- 1988-06-10 CA CA000569154A patent/CA1305418C/en not_active Expired - Lifetime
- 1988-06-10 AU AU17610/88A patent/AU609142B2/en not_active Expired
- 1988-06-10 JP JP63141872A patent/JP2654092B2/ja not_active Expired - Fee Related
- 1988-06-10 DK DK316788A patent/DK171746B1/da not_active IP Right Cessation
- 1988-06-10 IE IE174988A patent/IE62735B1/en not_active IP Right Cessation
- 1988-06-10 NO NO882559A patent/NO178096C/no not_active IP Right Cessation
- 1988-06-11 KR KR1019880007020A patent/KR970000506B1/ko not_active Expired - Fee Related
1993
- 1993-01-29 GR GR920402265T patent/GR3006938T3/el unknown

Also Published As

Publication number	Publication date
PT87704B (pt)	1993-03-31
IE881749L (en)	1988-12-12
KR970000506B1 (ko)	1997-01-13
IL86334A (en)	1992-09-06
JP2654092B2 (ja)	1997-09-17
DK316788D0 (da)	1988-06-10
NO882559D0 (no)	1988-06-10
NO882559L (no)	1988-12-13
GR3006938T3 (de)	1993-06-30
IE62735B1 (en)	1995-02-22
JPS6413024A (en)	1989-01-17
EP0294601A3 (en)	1989-10-11
ZA884186B (en)	1989-03-29
NO178096C (no)	1996-01-24
KR890000090A (ko)	1989-03-11
DK171746B1 (da)	1997-05-05
AU609142B2 (en)	1991-04-26
CA1305418C (en)	1992-07-21
DE3877630T2 (de)	1993-06-03
PT87704A (pt)	1988-07-01
AU1761088A (en)	1988-12-15
NZ224891A (en)	1992-06-25
EP0294601B1 (de)	1993-01-20
ES2043719T3 (es)	1994-01-01
DK316788A (da)	1988-12-13
DE3877630D1 (de)	1993-03-04
EP0294601A2 (de)	1988-12-14
NO178096B (no)	1995-10-16

Legal Events

Date	Code	Title	Description
1993-07-15	UEP	Publication of translation of european patent specification
2008-08-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
KR880700675A (ko)	1988-04-11	경피투여 시스템
FI883750A7 (fi)	1989-02-14	Transdermaalinen laastari lääkeaineen antamiseksi
FI895681A0 (fi)	1989-11-28	Farmaceutisk komposition foer systemisk transdermal tillfoersel.
DE3751761D1 (de)	1996-05-02	Penetrationsverbesserer für die transdermale Verabreichung von systemisch wirksamen Arzneimitteln
FI882791A7 (fi)	1988-12-13	Aineita, jotka parantavat määrättyjen 1,4-dihydropyridiinijohdannaisten siirtymistä ihon läpi.
FR2422402A1 (fr)	1979-11-09	Composition a base d'ester 3-b-methoxyethylique et 5-isopropylique de 1,4-dihydro-2,6-dimethyl-4-(3'-nitrophenyl) pyridine, destinee a la therapeutique cerebrale
DK0725779T3 (da)	2001-10-29	Hidtil ukendte (R)-5-Carbamoyl-8-fluor-3-N,N-disubstitueret-amino-3,4-dihydro-2H-1-benzopyraner
ATE211655T1 (de)	2002-01-15	Iontophoresematrix
DE3587794D1 (de)	1994-05-11	Pharmazeutische Präparate.
ATE56138T1 (de)	1990-09-15	Perfluorkohlenwasserstoffe als vehikel zur verabreichung von arzneimitteln.
SE8404065D0 (sv)	1984-08-10	Novel biologically active compounds
DE3877630D1 (de)	1993-03-04	Transkutane verabreichung von pharmazeutika.
IT8722501A0 (it)	1987-11-03	Formulazioni farmaceutiche per somministrazione transdermica.
ATE100465T1 (de)	1994-02-15	Analoge von bradykinin, dessen synthese und dessen benutzung in der therapie.
ATE20230T1 (de)	1986-06-15	Spasmolytisch wirksames (+)s-enantiomer von secoverin.
ATE81971T1 (de)	1992-11-15	Synergistische kombination von decarboxylasehemmern und l-dopa-pellets.
ATE84975T1 (de)	1993-02-15	Pharmazeutische praeparate.
DE3484155D1 (de)	1991-04-04	Fr-900216-verbindung, durch kultivierung von atcc 20577 gewonnen, als aktive therapeutische verbindung genutzt, und sie enthaltende antitumorale pharmazeutische zusammensetzung von fr-900216.
ATE26709T1 (de)	1987-05-15	Sparsomycin(sc-rs)-derivate; pharmazeutische zusammensetzung mit antitumorwirkung.