ATE85888T1 - Verfahren zur herstellung dispergierbarer kolloidaler systeme aus amphiphilen lipiden in form von liposomen in submikrongroesse. - Google Patents

Verfahren zur herstellung dispergierbarer kolloidaler systeme aus amphiphilen lipiden in form von liposomen in submikrongroesse.

Info

Publication number: ATE85888T1
Authority: AT; Austria
Prior art keywords: substance; preparation; dispersable; lipids; amphiphilic lipids
Prior art date: 1988-06-30

Application number

AT89401857T

Other languages

English (en)

Inventor

Serge Stainmesse

Hatem Fessi

Jean-Philippe Devissaguet

Francis Puisieux

Original Assignee

Centre Nat Rech Scient

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-06-30

Filing date

1989-06-28

Publication date

1993-03-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9367941&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE85888(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1989-06-28 Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient

1993-03-15 Application granted granted Critical

1993-03-15 Publication of ATE85888T1 publication Critical patent/ATE85888T1/de

Links

150000002632 lipids Chemical class 0.000 title abstract 4
239000002502 liposome Substances 0.000 title abstract 4
239000000084 colloidal system Substances 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
OMOVVBIIQSXZSZ-UHFFFAOYSA-N [6-(4-acetyloxy-5,9a-dimethyl-2,7-dioxo-4,5a,6,9-tetrahydro-3h-pyrano[3,4-b]oxepin-5-yl)-5-formyloxy-3-(furan-3-yl)-3a-methyl-7-methylidene-1a,2,3,4,5,6-hexahydroindeno[1,7a-b]oxiren-4-yl] 2-hydroxy-3-methylpentanoate Chemical compound CC12C(OC(=O)C(O)C(C)CC)C(OC=O)C(C3(C)C(CC(=O)OC4(C)COC(=O)CC43)OC(C)=O)C(=C)C32OC3CC1C=1C=COC=1 OMOVVBIIQSXZSZ-UHFFFAOYSA-N 0.000 abstract 3
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
239000007864 aqueous solution Substances 0.000 abstract 2
239000007791 liquid phase Substances 0.000 abstract 2
239000012071 phase Substances 0.000 abstract 2
239000000243 solution Substances 0.000 abstract 2
239000002904 solvent Substances 0.000 abstract 2
239000011877 solvent mixture Substances 0.000 abstract 2
239000000126 substance Substances 0.000 abstract 2
239000000725 suspension Substances 0.000 abstract 2
238000013019 agitation Methods 0.000 abstract 1
239000002537 cosmetic Substances 0.000 abstract 1
229940126601 medicinal product Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Manufacturing Of Micro-Capsules (AREA)
Cosmetics (AREA)

AT89401857T 1988-06-30 1989-06-28 Verfahren zur herstellung dispergierbarer kolloidaler systeme aus amphiphilen lipiden in form von liposomen in submikrongroesse. ATE85888T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8808874A FR2634375B3 (fr)	1988-06-30	1988-06-30	Procede de preparation de systemes colloidaux dispersibles de lipide amphiphiles sous forme de liposomes submicroniques
EP89401857A EP0349429B2 (de)	1988-06-30	1989-06-28	Verfahren zur Herstellung dispergierbarer kolloidaler Systeme aus amphiphilen Lipiden in Form von Liposomen in Submikrongrösse

Publications (1)

Publication Number	Publication Date
ATE85888T1 true ATE85888T1 (de)	1993-03-15

Family

ID=9367941

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89401857T ATE85888T1 (de)	1988-06-30	1989-06-28	Verfahren zur herstellung dispergierbarer kolloidaler systeme aus amphiphilen lipiden in form von liposomen in submikrongroesse.

Country Status (8)

Country	Link
EP (1)	EP0349429B2 (de)
JP (1)	JPH0824840B2 (de)
KR (1)	KR960014869B1 (de)
AT (1)	ATE85888T1 (de)
DE (1)	DE68904999T3 (de)
ES (1)	ES2054053T5 (de)
FR (1)	FR2634375B3 (de)
GR (2)	GR3007265T3 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20020150539A1 (en)	1989-12-22	2002-10-17	Unger Evan C.	Ultrasound imaging and treatment
DE4013580A1 (de) *	1990-04-24	1991-10-31	Schering Ag	Verfahren zur herstellung von wirkstoffhaltigen waessrigen liposomensuspensionen
ES2071081T3 (es) *	1990-06-11	1995-06-16	Idi Farmaceutici Spa	Liposomas fosfolipidicos que contienen principios activos y un procedimiento para su obtencion.
FR2668063A1 (fr) *	1990-10-17	1992-04-24	Fabre Pierre Cosmetique	Liposomes d'eaux thermales stabilises dans un gel d'adn.
US5205290A (en)	1991-04-05	1993-04-27	Unger Evan C	Low density microspheres and their use as contrast agents for computed tomography
EP0713387B1 (de) *	1993-08-06	1998-03-04	Opperbas Holding B.V.	Herstellungsverfahren von mit biologischen strukturen, biopolymeren und/oder oligomeren beladenen vesikeln
US7083572B2 (en)	1993-11-30	2006-08-01	Bristol-Myers Squibb Medical Imaging, Inc.	Therapeutic delivery systems
US6521211B1 (en)	1995-06-07	2003-02-18	Bristol-Myers Squibb Medical Imaging, Inc.	Methods of imaging and treatment with targeted compositions
US7452551B1 (en)	2000-10-30	2008-11-18	Imarx Therapeutics, Inc.	Targeted compositions for diagnostic and therapeutic use
US20010003580A1 (en)	1998-01-14	2001-06-14	Poh K. Hui	Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
AU2006200015B8 (en) *	1998-01-14	2008-02-21	Dupont Pharmaceuticals Company	Preparation of a lipid blend and a phospholipid suspension containing a lipid blend, and contrast agents based on these
JP4758915B2 (ja) *	2004-08-06	2011-08-31	バイオスペクトラム，インコーポレイテッド	多重層リポソームおよびその製造方法
KR101405417B1 (ko) *	2007-07-19	2014-06-12	(주)아모레퍼시픽	라이소인지질 콜로이드의 상거동을 이용하여 경피흡수도가조절된 피부 외용제의 제조방법
EP3138556B1 (de)	2014-04-30	2022-03-02	FUJIFILM Corporation	Verfahren zur herstellung von liposomen
IL296875A (en)	2014-12-31	2022-12-01	Lantheus Medical Imaging Inc	Fat-wrapped gas microsphere preparations and related methods
CN109641068B (zh)	2016-05-04	2022-09-30	蓝瑟斯医学影像公司	用于制备超声波造影剂的方法及装置
US9789210B1 (en)	2016-07-06	2017-10-17	Lantheus Medical Imaging, Inc.	Methods for making ultrasound contrast agents
IT201900004877A1 (it)	2019-04-01	2020-10-01	Res Pharma Ind S R L	Processo di preparazione di sistemi colloidali concentrati

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH621479A5 (de) *	1977-08-05	1981-02-13	Battelle Memorial Institute
GR77320B (de) *	1980-12-22	1984-09-11	Procter & Gamble
EP0069307B1 (de) *	1981-07-02	1986-03-05	F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft	Verfahren zur Herstellung von Liposomenlösungen
JPS607932A (ja) *	1983-06-29	1985-01-16	Dai Ichi Seiyaku Co Ltd	リポソーム懸濁液およびその製法
US4753788A (en) *	1985-01-31	1988-06-28	Vestar Research Inc.	Method for preparing small vesicles using microemulsification

1988
- 1988-06-30 FR FR8808874A patent/FR2634375B3/fr not_active Expired - Lifetime
1989
- 1989-06-28 DE DE68904999T patent/DE68904999T3/de not_active Expired - Fee Related
- 1989-06-28 EP EP89401857A patent/EP0349429B2/de not_active Expired - Lifetime
- 1989-06-28 AT AT89401857T patent/ATE85888T1/de not_active IP Right Cessation
- 1989-06-28 ES ES89401857T patent/ES2054053T5/es not_active Expired - Lifetime
- 1989-06-29 KR KR1019890009023A patent/KR960014869B1/ko not_active Expired - Fee Related
- 1989-06-30 JP JP1169742A patent/JPH0824840B2/ja not_active Expired - Lifetime
1993
- 1993-03-09 GR GR930400486T patent/GR3007265T3/el unknown
1996
- 1996-12-20 GR GR960403555T patent/GR3022121T3/el unknown

Also Published As

Publication number	Publication date
GR3022121T3 (en)	1997-03-31
EP0349429B2 (de)	1996-11-20
KR900000074A (ko)	1990-01-30
JPH02149336A (ja)	1990-06-07
GR3007265T3 (en)	1993-07-30
EP0349429A2 (de)	1990-01-03
EP0349429B1 (de)	1993-02-24
FR2634375B3 (fr)	1991-07-05
EP0349429A3 (en)	1990-08-22
KR960014869B1 (ko)	1996-10-21
ES2054053T3 (es)	1994-08-01
DE68904999D1 (de)	1993-04-01
FR2634375A1 (fr)	1990-01-26
JPH0824840B2 (ja)	1996-03-13
DE68904999T3 (de)	1997-06-12
DE68904999T2 (de)	1993-09-02
ES2054053T5 (es)	1997-01-16

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Legal Events

Date	Code	Title
1993-09-15	UEP	Publication of translation of european patent specification
1997-06-15	UEP	Publication of translation of european patent specification
2002-03-15	REN	Ceased due to non-payment of the annual fee