ATE86747T1 - Die sm-b/b1-antigene, das klonen der sm-b/b1antigene und der nachweis von systemischem lupus erythematosus unter verwendung der sm b/b1- antigene. - Google Patents

Die sm-b/b1-antigene, das klonen der sm-b/b1antigene und der nachweis von systemischem lupus erythematosus unter verwendung der sm b/b1- antigene.

Info

Publication number: ATE86747T1
Authority: AT; Austria
Prior art keywords: isolated; polypeptides; antigens; assay; living
Prior art date: 1987-09-15

Application number

AT88114945T

Other languages

English (en)

Inventor

Sallie O Hoch

Luis A Rokeach

Jeanne A Haselby

Original Assignee

Agouron Inst

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-09-15

Filing date

1988-09-13

Publication date

1993-03-15

1988-09-13 Application filed by Agouron Inst filed Critical Agouron Inst

1993-03-15 Application granted granted Critical

1993-03-15 Publication of ATE86747T1 publication Critical patent/ATE86747T1/de

Links

201000000596 systemic lupus erythematosus Diseases 0.000 title abstract 3
239000000427 antigen Substances 0.000 title 3
102000036639 antigens Human genes 0.000 title 3
108091007433 antigens Proteins 0.000 title 3
238000010367 cloning Methods 0.000 title 1
238000001514 detection method Methods 0.000 title 1
229920001184 polypeptide Polymers 0.000 abstract 7
102000004196 processed proteins & peptides Human genes 0.000 abstract 7
108090000765 processed proteins & peptides Proteins 0.000 abstract 7
239000000523 sample Substances 0.000 abstract 4
102000004190 Enzymes Human genes 0.000 abstract 3
108090000790 Enzymes Proteins 0.000 abstract 3
238000003556 assay Methods 0.000 abstract 3
238000004587 chromatography analysis Methods 0.000 abstract 3
239000002299 complementary DNA Substances 0.000 abstract 3
229940088598 enzyme Drugs 0.000 abstract 3
102000004169 proteins and genes Human genes 0.000 abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
210000002966 serum Anatomy 0.000 abstract 2
102000002260 Alkaline Phosphatase Human genes 0.000 abstract 1
108020004774 Alkaline Phosphatase Proteins 0.000 abstract 1
239000003298 DNA probe Substances 0.000 abstract 1
108010023244 Lactoperoxidase Proteins 0.000 abstract 1
102000045576 Lactoperoxidases Human genes 0.000 abstract 1
239000000020 Nitrocellulose Substances 0.000 abstract 1
108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
102000004598 Small Nuclear Ribonucleoproteins Human genes 0.000 abstract 1
108010003165 Small Nuclear Ribonucleoproteins Proteins 0.000 abstract 1
125000003275 alpha amino acid group Chemical group 0.000 abstract 1
239000013599 cloning vector Substances 0.000 abstract 1
230000000295 complement effect Effects 0.000 abstract 1
238000001502 gel electrophoresis Methods 0.000 abstract 1
238000004128 high performance liquid chromatography Methods 0.000 abstract 1
229940057428 lactoperoxidase Drugs 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229920001220 nitrocellulos Polymers 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
- G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
- G01N2800/104—Lupus erythematosus [SLE]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Hematology (AREA)
Engineering & Computer Science (AREA)
Urology & Nephrology (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
Rehabilitation Therapy (AREA)
Biotechnology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Rheumatology (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Enzymes And Modification Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT88114945T 1987-09-15 1988-09-13 Die sm-b/b1-antigene, das klonen der sm-b/b1antigene und der nachweis von systemischem lupus erythematosus unter verwendung der sm b/b1- antigene. ATE86747T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US9715987A	1987-09-15	1987-09-15
EP88114945A EP0307858B1 (de)	1987-09-15	1988-09-13	Die SM-B/B1-Antigene, das Klonen der SM-B/B1-Antigene und der Nachweis von systemischem Lupus erythematosus unter Verwendung der SM B/B1-Antigene

Publications (1)

Publication Number	Publication Date
ATE86747T1 true ATE86747T1 (de)	1993-03-15

Family

ID=22261589

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88114945T ATE86747T1 (de)	1987-09-15	1988-09-13	Die sm-b/b1-antigene, das klonen der sm-b/b1antigene und der nachweis von systemischem lupus erythematosus unter verwendung der sm b/b1- antigene.

Country Status (6)

Country	Link
EP (1)	EP0307858B1 (de)
JP (1)	JPH01147369A (de)
AT (1)	ATE86747T1 (de)
DE (1)	DE3879055T2 (de)
ES (1)	ES2053659T3 (de)
GR (1)	GR3007317T3 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5681700A (en) *	1994-05-25	1997-10-28	Oklahoma Medical Research Foundation	Assay for pathogenicity of anti-DNA antibodies
US6280944B1 (en)	1994-05-25	2001-08-28	Oklahoma Medical Research Foundation	Assay for pathogenicity of anti-DNA antibodies
EP0776906A3 (de) *	1995-10-19	1998-02-25	Imtec Immundiagnostika Gmbh	Peptide des Antigens Sm-D und ihre Verwendung, insbesondere für die Diagnostik des SLE
CN101256168B (zh) *	2008-04-22	2012-01-25	内蒙古蒙牛乳业（集团）股份有限公司	一种牛乳中乳过氧化物酶含量的检测方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4564597A (en) *	1981-03-18	1986-01-14	Research Corporation	Anti-Sm hybridoma
JPH01257263A (ja) *	1987-06-19	1989-10-13	Agouron Inst:The	Ｓｍ−ｄ抗原、ｓｍ−ｄ抗原のクローニングとｓｍ−ｄ抗原使用による播種性エリテマトーデの検出

1988
- 1988-09-13 ES ES88114945T patent/ES2053659T3/es not_active Expired - Lifetime
- 1988-09-13 DE DE8888114945T patent/DE3879055T2/de not_active Expired - Fee Related
- 1988-09-13 EP EP88114945A patent/EP0307858B1/de not_active Expired - Lifetime
- 1988-09-13 AT AT88114945T patent/ATE86747T1/de not_active IP Right Cessation
- 1988-09-16 JP JP63230238A patent/JPH01147369A/ja active Pending
1993
- 1993-03-11 GR GR930400333T patent/GR3007317T3/el unknown

Also Published As

Publication number	Publication date
DE3879055T2 (de)	1993-06-24
EP0307858A2 (de)	1989-03-22
EP0307858A3 (en)	1989-05-03
DE3879055D1 (de)	1993-04-15
GR3007317T3 (de)	1993-07-30
JPH01147369A (ja)	1989-06-09
EP0307858B1 (de)	1993-03-10
ES2053659T3 (es)	1994-08-01

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Legal Events

Date	Code	Title	Description
1993-08-15	UEP	Publication of translation of european patent specification
1995-06-15	REN	Ceased due to non-payment of the annual fee